Clinical trials: Vascular Access
Thrombosis, Venous Thrombosis
Safety and Efficacy Study of Alfimeprase in Subjects With Occluded Catheters
To evaluate the safety profile of alfimeprase as assessed by monitoring of adverse events, serious adverse events and major bleeding events for up to 120 minutes following the instillation of study drug to an occluded central…
- Conditions
- Thrombosis, Venous Thrombosis, Catheter Occlusion
- Trial name
- NCT00322270
- Testing
- Alfimeprase
- Where
- 18 sites in United States
- Sponsor
- ARCA Biopharma, Inc.
Severe Aortic Stenosis
Comparison of a Single Versus Double Perclose Technique for TAVR
Transcatheter aortic valve replacement (TAVR) has become widely recognized as a minimally invasive approach for aortic valve replacement in patients with severe aortic stenosis.
- Trial name
- Single (NCT06173115)
- Testing
- Perclose Proglide system
- Where
- 25 sites in China
- Volunteers
- 876 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Coronary Artery Disease, Radial Artery Spasm
Association Between Radial Artery Access Point and Radial Artery Spasm
This prospective clinical study aims to investigate whether the puncture site distance from the radial styloid process affects the incidence of radial artery spasm (RAS) during coronary angiography.
- Trial name
- NCT07060820
- Testing
- Radial Artery Puncture at 0-20 mm, Radial Artery Puncture at >21 mm
- Where
- Turkey (Türkiye)
- Volunteers
- 380 people
- Sponsor
- Mersin Medicalpark Hastanesi
Multiple Myeloma
Expanded Access Protocol (EAP) for Participants Receiving Idecabtagene Vicleucel That is Nonconforming for Commercial Release
This study is designed to evaluate the safety and efficacy of nonconforming idecabtagene vicleucel (ide-cel) in participants with multiple myeloma per the approved prescribing information.
- Trial name
- NCT04771078
- Testing
- Nonconforming idecabtagene vicleucel
- Sponsor
- Celgene
Malaria Infection, Pregnancy
Diagnostic Access to Self-Care and Health Services in Low and Middle Income Countries (DASH) - Phase II
Our primary goal is to determine if on-demand, home-based rapid testing, or rapid testing done by a community health worker (CHW) results in people testing for diseases more frequently and getting care more quickly.
- Conditions
- Malaria Infection, Pregnancy, HIV, Diabetes
- Trial name
- DASH (NCT06588790)
- Testing
- Home-based rapid testing, Community health worker rapid testing
- Where
- 3 sites in Kenya, South Africa and 1 more
- Volunteers
- 2,250 people, healthy volunteers welcome
- Sponsor
- University of Washington
Vascular Access Complication
Comparison of Brachial Wrist Index Before and After Implantation of Arteriovenous Fistulas, Based on Brachial Artery
Arterio-Venous Fistula (AVF) is the most recommended vascular access for hemodialysis. Steal syndrome is a potential complication of AVF implantation and occurs secondary to diversion of the arterial flow of a limb to the venous…
- Trial name
- NCT06365489
- Where
- Iran
- Volunteers
- 78 people
- Sponsor
- Golestan University of Medical sciences
End Stage Renal Disease, Arteriovenous Fistula
Role of Monocytes Adhesion and Vascular Lesions in Vascular Access Success or Failure in Uremic Patients
This study is designed to identify novel predictors of vascular access success or failure in chronic kidney disease patients. Despite efforts to improve placement of arteriovenous fistula (AVF) the primary failure rates are…
- Trial name
- ROMAVAS (NCT03231410)
- Where
- Poland
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Wroclaw Medical University
Radial Artery Occlusion, Cardiac Catheterization
Manual vs Pneumatic Compression to Prevent Radial Artery Occlusion After Transradial Procedures
This study evaluates two commonly used methods of achieving hemostasis after transradial cardiac catheterization: manual compression and pneumatic compression with gradual deflation.
- Trial name
- RADIAL-HEMO (NCT07621185)
- Testing
- Manual Radial Compression, Pneumatic Radial Compression Device
- Where
- Spain
- Volunteers
- 1,168 people
- Sponsor
- Hospital Clinic of Barcelona
Vascular Access Complication
Ultrasound vs Veinviewer in Patients With Difficulty IV Access
Patients with difficulty intravenous access frequently have delay of care in emergency departments because Emergency Department (ED) personnel could not establish intravenous (IV) access for diagnostic blood test or treatment.
- Trial name
- NCT02618252
- Testing
- Zonare, Veinviewer
- Where
- United States
- Sponsor
- University of Maryland, Baltimore
Crohn Disease, Ulcerative Colitis
Expanded Access to Upadacitinib
This is an expanded access program (EAP) for eligible participants. This program is designed to provide access to upadacitinib prior to approval by the local regulatory agency. Availability will depend on territory eligibility.
- Conditions
- Crohn Disease, Ulcerative Colitis, Idiopathic Arthritis (Including sJIA, pJIA, or JPsA), Atopic Dermatitis
- Trial name
- NCT04159597
- Testing
- Upadacitinib
- Sponsor
- AbbVie
Arteriovenous Fistula Complications and Failure
Clipped Versus Handsewn Arteriovenous Fistula Anastomosis
The purpose of this study is to determine whether handsewn anastomosis versus clipped technique is associated with more complications, fistula failures, surgical cost and surgical time.
- Trial name
- NCT01669850
- Testing
- Clipped anastomosis, Handsewn anastomosis
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Gundersen Lutheran Medical Foundation
Atrial Fibrillation (AF), Vascular Access
StatSeal vs Figure-of-Eight Suture for Vascular Closure in AF Ablation
This study, titled aims to compare two vascular closure techniques after catheter ablation for atrial fibrillation (AF). Catheter ablation is a common procedure used to treat AF, but after the procedure, It is important to close…
- Trial name
- NCT06627959
- Testing
- Statseal, Figure of eight suture
- Where
- 3 sites in United Kingdom
- Volunteers
- 160 people
- Sponsor
- Mid and South Essex NHS Foundation Trust
Vascular Access Complications
Micropuncture vs. Standard Common Femoral Artery Access
Vascular access complications can occur during or after cardiac or peripheral arterial catheterization. These complications increase patient morbidity and mortality, as well as healthcare costs.
- Trial name
- NCT02026180
- Testing
- Micropuncture Access
- Where
- United States
- Volunteers
- 552 people
- Sponsor
- North Texas Veterans Healthcare System
Unspecified Adult Solid Tumor, Protocol Specific, Vascular Access Device Complications
Study Comparing Two Types of Ports in Patients With Cancer Receiving Intravenous Chemotherapy
RATIONALE: Giving chemotherapy drugs through an implanted port reduces the need for multiple needle sticks. It is not yet known whether one type of port is more effective than another in reducing infections and other side effects…
- Trial name
- NCT00607880
- Testing
- vascular access device placement
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Renal Failure Chronic Requiring Hemodialysis
Hemodialysis Reliable Outflow (HeRO) Vascular Access Patency Study
Compare the HeRO Vascular Access Device to a conventional ePTFE graft.
- Trial name
- NCT00890045
- Testing
- HeRO Vascular Access Device, Conventional ePTFE hemodialysis graft
- Where
- 11 sites in United States
- Volunteers
- 72 people
- Sponsor
- Merit Medical Systems, Inc.
Waldenström Macroglobulinemia
A Single-Arm, Expanded Access Study of Zanubrutinib in Participants With B-cell Malignancies
This is a multicenter expanded access study of zanubrutinib monotherapy for participants with B-cell malignancies who are ineligible to enroll into any available zanubrutinib clinical trials
- Trial name
- NCT04052854
- Testing
- Zanubrutinib
- Where
- 10 sites in United States
- Sponsor
- BeiGene
Atherosclerotic Cardiovascular Disease, ASCVD
Managed Access Programs for TQJ230, Pelacarsen
The purpose of this registration is to list Managed Access Programs (MAPs) related to TQJ230, pelacarsen
- Trial name
- NCT07000695
- Testing
- Pelacarsen
- Sponsor
- Novartis Pharmaceuticals
Acute Coronary Syndrome
AngioSeal Versus Radial Approach in Acute Coronary Syndrome
Among non-ST-segment elevation acute coronary syndrome patients submitted to early invasive strategy and randomized for the transfemoral or transradial approach, the AngioSeal vascular closure device would decrease the prevalence…
- Trial name
- ARISE (NCT01653587)
- Testing
- Percutaneous coronary intervention
- Where
- Brazil
- Volunteers
- 240 people
- Sponsor
- Irmandade Santa Casa Misericórdia Marília
Cardiac Arrest Due to Underlying Cardiac Condition, Ventricular Fibrillation
ACCESS to the Cardiac Cath Lab in Patients Without STEMI Resuscitated From Out-of-hospital VT/VF Cardiac Arrest
To determine if survival to hospital discharge with good neurological outcome for adults ages 18-75 who are resuscitated from out-of-hospital VT/VF cardiac arrest without clinical signs of a heart attack do better by going…
- Conditions
- Cardiac Arrest Due to Underlying Cardiac Condition, Ventricular Fibrillation, Cardiopulmonary Arrest With Successful Resuscitation
- Trial name
- NCT03119571
- Testing
- Initial CCL admission, Initial ICU admission
- Where
- 23 sites in United States, Canada
- Volunteers
- 65 people
- Sponsor
- University of Minnesota
Pain, Child, Only
The Effect of The Musical Toy Used During Peripheral Vascular Access on Children's Pain, Fear And Parents' Satisfaction
The research was carried out as a randomized controlled experimental study in order to examine the effects of the child's pain, fear and parent's satisfaction before and after vascular access with a musical toy-xylophone, which…
- Conditions
- Pain, Child, Only, Parents
- Trial name
- NCT05689411
- Testing
- Musical Toy
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Ordu University