Clinical trials: Validity and Safety
Penicillin Allergy
Amoxicillin Challenge for Penicillin Allergy Diagnosis
False diagnosis of penicillin allergy are frequently reported, and have been proven detrimental to patients. Current guidelines for the assessment of drug allergies recommend that penicillin allergy be evaluated first with prick…
- Trial name
- Pen-VIE (NCT03757052)
- Testing
- Penicillin Skin Testing
- Where
- Canada
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Quality of Life, Epilepsy (treatment Refractory)
Evaluation of the Epilepsy-related Quality of Life, Seizure-related Accidents and Validation of the Mjn-SERAS Solution in the Normalised Patient Environment with Real-World Data
The study will be prospective, multicentre, postmarketing clinical study, with a controlled and randomized design, to perform the analysis of 130 subjects with a clinical diagnosis of epilepsy, patients whose clinical semiology…
- Trial name
- SERAS_Home_RWD (NCT05845255)
- Testing
- mjn-SERAS
- Where
- 6 sites in Germany, Spain and 1 more
- Volunteers
- 130 people
- Sponsor
- MJN Neuroserveis, S.L
Alzheimer Disease
The Safety and Scientific Validity of Low-dose Whole Brain Radiotherapy in Alzheimer's Disease.
Alzheimer's disease is the most frequent neurocognitive disorder associated with dementia, with a constantly increasing prevalence associated with an aging population.
- Trial name
- NCT04203121
- Testing
- low dose whole brain radiation to treat Alzheimer disease
- Where
- South Korea
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Kyung Hee University Hospital at Gangdong
Sepsis
Evaluation of the Patient Safety Screening Tool (PSST) for Sepsis
The Patient Safety Screening Tool (PSST) for Sepsis solution is a tool to assist with the early detection of Sepsis and management of the administration of bundle packages as defined by the Institute for Healthcare Improvement…
- Trial name
- NCT00698542
- Where
- United States
- Volunteers
- 221 people
- Sponsor
- Vanderbilt University
HIV Infections
Safety and Efficacy Study of KP-1461 to Treat ART-Experienced HIV+ Patients
The primary purpose of the study is to investigate the safety and efficacy of KP-1461 given every 12 hours for 124 days to HIV+ patients who have failed multiple antiretroviral regimens.
- Trial name
- NCT00504452
- Testing
- KP-1461
- Where
- 31 sites in United States, Puerto Rico
- Volunteers
- 27 people
- Sponsor
- Koronis Pharmaceuticals.
Healthy Subjects, Chronic Conditions, Multiple
Heart Rate and Respiratory Rate Measurements by a Novel, Radar-based Device
A single center, single blinded, prospective validation (including extension0 study for the accuracy and safety evaluation of Neteera 130H, a novel, radar-based contact-free device for heart and respiratory rate measurements.
- Trial name
- NCT04796181
- Testing
- Neteera 130H
- Where
- 2 sites in United States, Israel
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Neteera Technologies Ltd.
Cervical Intraepithelial Neoplasia, Cervical Cancer
Visual Inspection With Acetic Acid Compared to Lugol's Iodine in HIV-infected Women
The clinical trial is part of a larger study to evaluate the safety and efficacy of screening techniques for cervical cancer among HIV-infected women.
- Conditions
- Cervical Intraepithelial Neoplasia, Cervical Cancer, HIV
- Trial name
- SAVE (NCT02237326)
- Testing
- Visual Inspection with Acetic Acid, Visual Inspection with Lugol's Iodine
- Where
- Kenya
- Volunteers
- 654 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Idiopathic Pulmonary Fibrosis
Study to Test the Validity of the Treatment of Idiopathic Pulmonary Fibrosis With Cotrimoxazole
First study to test the validity of the treatment of idiopathic pulmonary fibrosis, which causes inflammation and fibrosis (scarring) of the lung tissue, with cotrimoxazole.
- Trial name
- TriSulfa-FPI (NCT01777737)
- Testing
- Cotrimoxazole
- Where
- Spain
- Volunteers
- 3 people
- Sponsor
- Fundación Pública Andaluza para la gestión de la Investigación en Sevilla
Cancer
Validation of an Adjusted Dosing Algorithm of Carboplatin
An adjusted dosing algorithm for the dosing of the anticancer drug carboplatin has been developed, that accounts for high BMI, low serum creatinine values and maximal calculated renal function.
- Trial name
- NCT02103244
- Testing
- Carboplatin
- Where
- Netherlands
- Volunteers
- 24 people
- Sponsor
- Rijnstate Hospital
Functional Dyspepsia
Phase Ⅱc Sutdy of Aolanti Weikang Tablets in FD PDS Patients
The purpose of this study is to evaluate the safety and validity of Aolanti Weipang Tablets in Patients with Postprandial Discomfort Syndrome of Functional Dyspepsia
- Trial name
- NCT03971383
- Testing
- Aolanti Weipang Tablets
- Where
- China
- Volunteers
- 236 people
- Sponsor
- Jiangxi Qingfeng Pharmaceutical Co. Ltd.
Chronic Kidney Diseases, Protein-Energy Malnutrition
Effect of a Specialized Oral Supplement on Nutritional Status and Quality of Life in Non-dialysis CKD
Patients whit chronic kidney disease (CKD) there is a high prevalence of nutritional disorders and negative changes in body composition, which is strongly associated with an increased risk of morbidity and mortality.
- Trial name
- NCT06576479
- Testing
- Nutritious Shake, Nutritional counseling
- Where
- Mexico
- Volunteers
- 50 people
- Sponsor
- NIN Institute
Stroke, Exercise
Community-based Complex Exercise for Stroke Patients
A lot of physical and social effects of exercise programs and daily physical education have already been proven for stroke patients after discharge.
- Trial name
- COB-CEPS (NCT06012396)
- Testing
- Stoke complex exercise program
- Where
- South Korea
- Volunteers
- 126 people
- Sponsor
- Pusan National University Yangsan Hospital