Clinical trials: Vaginal Delivery
Numerical Rating Pain Score, the Total Doses of Pethidine Needed Through-out Delivery Will be Measured
Thoracic Erector Spinae Plane Block for Painless 1st Stage Normal Vaginal Delivery: Randomized Controlled Study
this study will test a novel indication for bilateral erector spinae plane block (painless 1st stage normal vaginal delivery) it depends on the hypnosis that the erector spinae plane block blocks the visceral pain also by…
- Conditions
- Numerical Rating Pain Score, the Total Doses of Pethidine Needed Through-out Delivery Will be Measured, the Incidence of Failed Delivery and Need of Cesarean Section Will be Assessed, the Incidence of Transient Fetal Bradycardia or Deceleration After the Administration of the Block Will be Recorded
- Trial name
- NCT04981353
- Testing
- bilateral erector spinae plane block at T11
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ain Shams University
Vaginal Delivery
Failed Epidural Anesthesia During Labor: Evaluation of Risk Factors and Outcome
Women requesting epidural analgesia will receive a bolus of intravenous infusion of lactated Ringer's solution before initiation of the procedure.
- Trial name
- NCT03129022
- Testing
- epidural anaesthesia
- Where
- Egypt
- Volunteers
- 500 people
- Sponsor
- Cairo University
Fear of Childbirth, Primiparous Women
QR-Based Virtual Tour and Childbirth Outcomes
Childbirth is a unique experience that affects maternal health physiologically, emotionally, and socially, and represents a crucial step in the transition to motherhood.
- Conditions
- Fear of Childbirth, Primiparous Women, Vaginal Birth Rate, Childbirth Readiness
- Trial name
- VIRTU-BIRTH (NCT07496879)
- Testing
- Virtual Delivery Room Tour via QR Codes
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Obstetric Labor, Premature
Randomized Controlled Trial of Vaginal Progesterone in Women With Threatened Preterm Labor
Prematurity remains the most important single factor in perinatal morbidity and mortality. Unfortunately, the rate of premature delivery is increasing in Canada and is especially high in Alberta with 7.5% of pregnancies ending…
- Trial name
- PROTO (NCT01286246)
- Testing
- Vaginal progesterone
- Where
- Canada
- Volunteers
- 34 people
- Sponsor
- University of Calgary
Labor Induction, Induced Delivery
Foley Catheter Versus PGE2 for Labor Induction at Term: a Pilot Study
Induction of labor is one of the most common interventions in obstetrics. In the past decade, the rates of labor induction at term have doubled from approximately 9% to 23% in the United States and from 10% to 20.4% in China.
- Trial name
- NCT04780269
- Testing
- Induction of labor with Foley catheter, Induction of labor with PGE2
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Pelvic Floor Disorders
Effects of Flourish HEC Vaginal Care System on Birth-Related Pelvic Floor Disorders
The goal of this clinical trial is to learn about how the vaginal microbiome affects pelvic floor disorders in women who have recently given birth.
- Trial name
- NCT05665569
- Testing
- Flourish HEC, which contains BioNourish, Routine pelvic physical therapy
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Vaginal Biome Science
Bacterial Vaginosis, Fetal Membranes, Premature Rupture
Perinatal Infections in Pakistan
There are large differences in health outcomes related to pregnancy and birth between developed and developing countries. This study will investigate how infections, medical history, health care behavior and psychosocial issues…
- Conditions
- Bacterial Vaginosis, Fetal Membranes, Premature Rupture, Chorioamnionitis, Pregnancy
- Trial name
- NCT00070746
- Where
- Pakistan
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- NICHD Global Network for Women's and Children's Health
Post Partum Hemorrhage
Amr Maneuver for Prevention of Postpartum Hemorrhage
The patients were divided randomly in to 2 GROUPS: control group: 153 patients received Oxytocin 10 IU I.V shot administered at the time of delivery of the anterior shoulder of the baby according to the WHO recommendation for…
- Trial name
- NCT04401839
- Testing
- Oxytocin IV shot, Oxytocin IV drip, Amr maneuver
- Where
- Egypt
- Volunteers
- 306 people, healthy volunteers welcome
- Sponsor
- Cairo University
Forceps Delivery Affecting Fetus or Newborn, Ventouse Extraction;Liveborn
Learning Curves of Different Devices for Vaginal Birth on Mannequin
Learning curves for residents and specialists for devices applied on operative vaginal birth on mannequin (Odòn, Kiwi, Simpson forceps)
- Conditions
- Forceps Delivery Affecting Fetus or Newborn, Ventouse Extraction;Liveborn, Birth; Forced
- Trial name
- NCT06923319
- Testing
- Odòn, Kiwi, Simpson skills
- Where
- 2 sites in Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- G. d'Annunzio University
Site Infection, Cesarean Section; Complications, Wound, Infection (Following Delivery)
Vaginal Microbiota and Post-cesarean SSI
The goal of this observational study is to investigate the relationship between vaginal microbiota composition and the development of post-cesarean section wound infection in women undergoing cesarean delivery.
- Trial name
- NCT06840041
- Testing
- Vaginal swab and culture
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Preterm
Cerclage Plus Progesterone vs Progesterone Alone in Twin Short Cervix
This study aims to compare the effectiveness of cervical cerclage combined with progesterone versus progesterone alone in preventing preterm birth among women with twin pregnancies and a short cervix (cervical length ≤ 30 mm).
- Trial name
- VNTWINC (NCT07372495)
- Testing
- Cervical cerclage, Progesterone
- Where
- 6 sites in Vietnam
- Volunteers
- 260 people
- Sponsor
- National Hospital of Obstetrics and Gynecology
Trial of Labor After Cesarean, Vaginal Birth After Cesarean
Balloon Catheter Combined With Oxytocin Induction Among the Pregnant Women With Previous Cesarean Section
This study is a multi-center, prospective, observational clinical trial study. 924 full-term pregnant women will be enrolled as subjects, and the ratio of eligible subjects in the two groups is 1:1.
- Conditions
- Trial of Labor After Cesarean, Vaginal Birth After Cesarean, Bishop Score, Failed Mechanical Induction
- Trial name
- NCT05246761
- Testing
- Balloon catheter
- Where
- China
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Antifungal Drug Adverse Reaction
An Open-label Study to Evaluate the Effects of Concurrent Administration of Vaginal Antimycotic Medication Miconazole Nitrate on the Pharmacokinetics of Nestorone and Ethinyl Estradiol Delivered by a Contraceptive Vaginal Ring in Normal Ovulating Women
To evaluate the pharmacokinetics (PK) of EE and NES released from the CVR in the presence of a single dose and multiple doses of antimycotic co-medication (miconazole nitrate suppository or cream).
- Trial name
- NCT02215395
- Testing
- NES/EE CVR
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Population Council
Delivery Uterine
Noninvasive Continuous Measurement of SpHb After Spontaneous Vaginal Delivery
Aim of this study is to determine the physiological reference individual values (RI) of maternal continuous SpHb immediately after delivery in the post-partum period (continuous monitoring up to 2 hours after delivery) in order…
- Trial name
- NCT01505192
- Testing
- continuous Hb monitor
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- Città di Roma Hospital
Postpartum Hemorrhage
Administration Of Calcium Gluconate for The Reduction of Blood Loss During Vaginal Delivery
Postpartum hemorrhage is one of the leading causes of maternal morbidity following childbirth. Even when excessive bleeding is not clinically recognized, some women experience a significant decrease in hemoglobin levels after…
- Trial name
- NCT07714902
- Testing
- calcium gluconate
- Where
- Israel
- Volunteers
- 710 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Induced; Birth, Cervical Dilatation
Induction to Labour With Double Cervical Ballon at Home Versus at Hospital
The goal of this clinical trial] is to compare the outcomes between induction to labour at home versus hospitalized. The main questions it aims to answer are: Can the induction to labour at home with cervical rippening ballon…
- Conditions
- Induced; Birth, Cervical Dilatation, Live Birth
- Trial name
- INDOBAMHOS (NCT06053073)
- Testing
- Cervical rippening at home, Cervical rippening in the hospital
- Where
- Spain
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Low Back Pain and Core Muscle
Low Back Pain Intensity and Core Muscle Strength After Different Delivery Modes
Cesarean delivery (CD) may trigger an increase in low back pain (LBP) intensity and induce core muscle weakness. This study will assess the correlation between low back pain intensity and core muscle strength of transverse…
- Trial name
- NCT05493891
- Testing
- Visual analogue scale (VAS), Pressure Biofeedback Unit (PBU)
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- South Valley University
Postpartum Hemorrhage, Vaginal Delivery
Reducing Postpartum Hemorrhage After Vaginal Delivery
Postpartum hemorrhage is the primary cause threatening the life safety of pregnant women in the world and China, and also the main cause of hysterectomy for women giving birth.
- Trial name
- NCT05501106
- Testing
- Integrated Improvement strategies
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Peking University Third Hospital
Contraception, Birth Control
Safety of a Contraceptive Copper Vaginal Ring
Many birth control options today come with unwanted side effects or risks. Hormonal methods can affect both mental and physical health, while devices like copper IUDs carry risks such as uterine perforation or infection.
- Conditions
- Contraception, Birth Control, Pregnancy Prevention
- Trial name
- NCT07666997
- Testing
- Vaginal Ring
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Elle, MD Biotechnologies Inc.
Healthy
Ethylvinyl Acetate (EVA) Vaginal Ring Delivery System Study
This research study is looking at how well a new drug delivery system, called the vaginal ring, works to get hormones into your body as a form of birth control.
- Trial name
- VaginalRing (NCT00706784)
- Testing
- Ethylvinyl Acetate (EVA) Vaginal Ring Delivery System
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital