Clinical trials: VT Ablation
Ventricular Tachycardia, Sustained, Ventricular Tachycardia, Monomorphic
Cryoablation for Monomorphic Ventricular Tachycardia (VTS)
The objective of this clinical study is to evaluate the safety and effectiveness of the Adagio Medical vCLAS Ventricular Ablation System (including VTS Catheter and Console) in the ablation treatment of Sustained Monomorphic…
- Trial name
- FULCRUM-VT (NCT07650032)
- Testing
- Ultra Low Temperature Ablation (ULTA)
- Where
- 10 sites in United States, Canada
- Volunteers
- 100 people
- Sponsor
- Adagio Medical
Ventricular Tachycardia, End-stage Heart Failure
Ventricular Tachycardia Ablation in LVAD Patients
The CHANNELED-Registry is a multicenter retrospective study to (1) systematically assess the mechanism and origin of ventricular tachycardia in patients with end-stage heart failure carrying an left ventricular assist device…
- Conditions
- Ventricular Tachycardia, End-stage Heart Failure, Ventricular Arrythmia, LVAD (Left Ventricular Assist Device)
- Trial name
- CHANNELED (NCT06063811)
- Testing
- Ablation
- Volunteers
- 50 people
- Sponsor
- Universitätsklinikum Köln
Ventricular Tachycardia (VT)
Dynamic Voltage Mapping to Personalise the Ventricular Tachycardia Substrate
Ventricular tachycardia (VT) is a life-threatening heart rhythm disorder and one of the commonest causes of heart-related sudden death. It often affects people who have had a heart attack or other structural heart damage.
- Trial name
- DYNAMITE-VT (NCT07573579)
- Testing
- Dynamic Voltage Mapping, Standard of Care Ablation
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Ventricular Tachycardia, Ischemic Cardiomyopathy
Ablation at Virtual-hEart pRedicted Targets for VT
The goal of this study is to test the efficacy of the new imaging/simulation ("virtual heart") approach for determining the optimal ablation sites in patients with VT, which render post-infarction VT non-inducible.
- Trial name
- AVERT-VT (NCT03536052)
- Testing
- Virtual Heart Guided Ablation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Johns Hopkins University
Cerebral Oxygenation
Cerebral Oxygenation and Awareness During VT Ablation
It is aimed to examine the effect of the decrease in blood pressure that occurs during the ventricular tachycardia ablation process on cerebral oxygenation and awareness.
- Trial name
- NCT05097170
- Testing
- NIRS during ventricular tachycardia ablation
- Where
- Turkey (Türkiye)
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Focal Ventricular Arrhythmias, Premature Ventricular Contractions
Treatment of Focal Ventricular Tachycardias Using a Pulsed Field Ablation From a Point Ablation Catheter Short Title FOCUS-PFA
The purpose of this study is to examine the use of a point ablation catheter (Farapoint, Boston Scientific) in the mapping and ablation of focal ventricular arrhythmias (premature ventricular contractions or ventricular…
- Conditions
- Focal Ventricular Arrhythmias, Premature Ventricular Contractions, Ventricular Tachycardias
- Trial name
- FOCUS PFA (NCT06747013)
- Testing
- Point Ablation Catheter
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Vivek Reddy
Ventricular Tachycardia (VT)
Pan-Asia United States PrEvention of Sudden Cardiac Death Catheter Ablation Trial
The current standard of care for ventricular tachycardia (VT) includes the use of medicine called anti-arrhythmic drugs (AADs) and Implantable Cardioverter Defibrillator (ICD) therapy.
- Trial name
- PAUSE-SCD (NCT02848781)
- Testing
- Implantable Cardioverter Defibrillator (ICD), Catheter Ablation
- Where
- 12 sites in United States, China and 3 more
- Volunteers
- 180 people
- Sponsor
- University of Arizona
Ventricular Tachycardia, Ischemic Heart Disease
Real-time Automated Program for IDentification of VT Origin
RAPID-VT Pilot is a single centre prospective cohort pilot study to assess the feasibility, safety and efficacy of catheter ablation of ventricular tachycardia (VT) guided by a novel real-time software to localize the origin of…
- Trial name
- RAPIDVTPilot (NCT03523286)
- Testing
- RAPID-VT Software guided ablation
- Where
- Canada
- Volunteers
- 8 people
- Sponsor
- Amir AbdelWahab
Heart Failure
Primary Preventive Ventricular Tachycardia Ablation In High-Risk Patients Who Receive A Prophylactic Implantable Cardioverter Defibrillator
This prospective, multicenter, open-label, randomized-controlled trial compares two treatment strategies in high-risk ischemic cardiomyopathy (ICM) patients referred for primary ICD implantation.
- Trial name
- PREVENT-VT (NCT06543173)
- Testing
- Prophylactic Catheter-based VT Ablation
- Where
- 5 sites in Denmark, France and 1 more
- Volunteers
- 62 people
- Sponsor
- University of Rochester
Ischemic Monomorphic Ventricular Tachycardia
Physician Assessment of the Clinical Utility of a Patient-Specific 3D Electro-Anatomical Heart Model in VT Ablation
ACE-VT is a clinical pilot study designed to evaluate the ability of the CardioSolv Software System to generate an output for the physician to review in a timely fashion, consistent with the standard of care VT ablation workflow.
- Trial name
- ACE-VT (NCT04841382)
- Testing
- Supporting information.
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- CardioSolv Ablation Technologies
Ventricular Tachycardia
Physiologically Guided VT Ablation
The purpose of this study is to determine the efficacy of VT ablation guided by functional evaluation of the substrate to specifically target the reentry-vulnerable zones in patients with infarct-related VT.
- Trial name
- NCT04004624
- Testing
- Ablation
- Volunteers
- 80 people
- Sponsor
- Center for Cardiovascular Reseach and Innovation
Ventricular Tachycardia
Bipolar Ventricular Tachycardia (VT) Study
This non-randomized study will examine the safety and efficacy of irrigated bipolar radiofrequency (RF) ablation in the treatment of ventricular tachycardia (VT) in patients for whom standard VT unipolar RF ablation has been…
- Trial name
- NCT02374476
- Testing
- Bipolar Ablation
- Where
- 6 sites in United States
- Volunteers
- 145 people
- Sponsor
- Srinivas Dukkipati
Ventricular Tachycardia, Arrhythmia
Imaging With a Radio Tracer to Guide VT Ablations
Some patients are at risk for life-threatening fast heart rates. These can frequently be treated by using a catheter inside the heart to burn away the cells that create the fast heart rates.
- Trial name
- NCT01250912
- Testing
- 123I-metaiodobenzylguanidine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Maryland, Baltimore
Ventricular Tachycardia, Catheter Ablation
Stepwise Approach To sUbstrate Modification for Ventricular Tachycardia
The goal of this trial is to test the impact of a step-wise approach for catheter ablation of recurrent ventricular tachycardia, (irregular heart rhythms that originate in the bottom chambers of the heart), in patients with a…
- Conditions
- Ventricular Tachycardia, Catheter Ablation, Tachycardia, Ventricular
- Trial name
- STRATUM VT (NCT01546207)
- Testing
- catheter-based ablation
- Where
- 10 sites in United States, Brazil and 3 more
- Volunteers
- 4 people
- Sponsor
- Vivek Reddy
Ventricular Tachycardia (VT), Ischemic Cardiomyopathy
Targeted Ablation to Isolate Scar Channels Causing Ventricular Tachycardia
The goal of this study is to map conducting channels within scar that cause ventricular tachycardia (VT) in patients with scar in their hearts in order to block these channels from causing VT with targeted radiofrequency ablation…
- Conditions
- Ventricular Tachycardia (VT), Ischemic Cardiomyopathy, Nonischemic Cardiomyopathy
- Trial name
- NCT07814079
- Testing
- Selective Substrate Isolation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- New York Medical College
Refractory Ventricular Tachycardia
Saline Enhanced Radiofrequency (SERF) Needle Ablation for Refractory VT
The Thermedical Ablation System and Durablate catheter is indicated for use in patients with recurrent, sustained, monomorphic ventricular tachycardia (SMVT) refractory to drug therapy and conventional (approved) catheter…
- Trial name
- NCT05337241
- Testing
- Saline Enhanced Radiofrequency (SERF) Ablation
- Where
- 7 sites in United States, Canada
- Volunteers
- 130 people
- Sponsor
- Thermedical, Inc.
Ventricular Tachycardia (VT), Premature Ventricular Contraction (PVC)
Computational Cardiac Imaging Analysis to Guide Ventricular Tachycardia Ablation Procedures (AI-VT)
The purpose of this study is to evaluate the clinical outcomes (clinical efficacy and safety) of using supplemental non-invasive computational ECG and cardiac imaging analysis tools to help guide ablation of ventricular…
- Conditions
- Ventricular Tachycardia (VT), Premature Ventricular Contraction (PVC), Ventricular Fibrillation
- Trial name
- AI-VT (NCT06964152)
- Testing
- Computational electrocardiography and cardiac computed tomography mapping
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of California, San Diego
Tachycardia, Ventricular
Comparison of VT Ablation Outcomes Using Remote MAGNETIC Navigation Versus Manual Approach in a Low LVEF Population
The study purpose is to demonstrate that ventricular tachycardia (VT) ablation using the Niobe™ ES system results in superior outcomes compared to a manual approach in subjects with ischemic scar VT in a low ejection fraction…
- Trial name
- MAGNETIC-VT (NCT02637947)
- Testing
- catheter ablation using magnetic navigation, catheter ablation using manual navigation
- Where
- 16 sites in United States, Australia and 5 more
- Volunteers
- 182 people
- Sponsor
- Stereotaxis
Atrial Fibrillation (AF), Atrial Flutter
Electrophysiological Registry Duesseldorf
This registry at University Hospital Düsseldorf collects retrospective and prospective (from 2019 onward) data on patients undergoing electrophysiological studies (EPS), catheter ablation, and electrical cardioversion.
- Conditions
- Atrial Fibrillation (AF), Atrial Flutter, Supraventricular Tachycardias, Ventricular Tachycardia (VT)
- Trial name
- NCT07196176
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Ischemic Ventricular Tachycardia
Dynamic Substrate Mapping (DSM) for Ischemic VT
This is a prospective, non-randomized study to determine the feasibility of using a new technique called Dynamic Substrate Mapping (DSM) to help guide the treatment of ischemic ventricular tachycardia (IVT).
- Trial name
- DSM (NCT00558857)
- Testing
- Dynamic Substrate Mapping-guided ablation
- Where
- 3 sites in United States
- Volunteers
- 5 people
- Sponsor
- Abbott Medical Devices