Clinical trials: VT
Ventricular Tachycardia (VT)
Cardiac RadiothErapy for VEntricular Tachycardia II
Steoreotactic therapy radioablation has become a standard of care option for patients with therapy-refractory ventricular tachycardia, yet long-term outcome is lacking.
- Trial name
- CREVET II (NCT06744530)
- Testing
- stereotactic radiotherapy ablation
- Where
- Belgium
- Volunteers
- 50 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Heart Failure With Reduced Ejection Fraction (HFrEF), Ventricular Tachycardia (VT)
Metabolomic Profiling in Ischemic and Non-Ischemic Cardiomyopathy Patients With Ventricular Arrhythmias
This single-center prospective observational study aims to evaluate differences in metabolomic pathways between patients with ischemic and non-ischemic cardiomyopathy with reduced left ventricular ejection fraction and documented…
- Conditions
- Heart Failure With Reduced Ejection Fraction (HFrEF), Ventricular Tachycardia (VT), Ischemic Cardiomyopathy, Non-ischemic Cardiomyopathy
- Trial name
- MET-CMP (NCT07507539)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Muhammed Heja Geçit
Ventricular Tachycardia (VT)
Sympathetic Ablation for Ventricular Arrhythmias
Enrolled patients will undergo an acute procedure in which a catheter is inserted near the heart to ablate a sympathetic nerve, reducing signals that trigger ventricular arrhythmias.
- Trial name
- NCT07501819
- Testing
- Central sympathetic nerve ablation
- Volunteers
- 10 people
- Sponsor
- SymKardia
Ventricular Tachycardia (VT)
Non-Invasive Programmed Stimulation (NIPS) to Guide the Subsequent VT Therapeutic Strategies
The aim of this study is to define the importance of non-invasive programmed stimulation (NIPS) in risk stratification of ventricular tachycardia (VT) recurrence after catheter ablation and to determine the optimal treatment…
- Trial name
- NCT06669299
- Testing
- Re-Do ventricular tachycardia ablation, Antiarrhythmic Drug Therapy (amiodarone, sotalol, or mexiletine)
- Where
- Italy
- Volunteers
- 51 people
- Sponsor
- IRCCS Ospedale San Raffaele
Atrial Fibrillation, Atrioventricular Block, Second and Third Degree
Predicting Severe Cardiac Arrhythmias in the Perioperative Period Using AI-ECG
During the preoperative examination, in addition to the standard examination recommended before high-risk cardiac surgeries, a digital single-lead ECG is recorded using portable CardioQUARK devices.
- Conditions
- Atrial Fibrillation, Atrioventricular Block, Second and Third Degree, Sinus Node Dysfunction, Ventricular Tachycardia (VT)
- Trial name
- NCT07348991
- Testing
- digital single-channel ECG recording
- Volunteers
- 300 people
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Atrial Fibrillation (AF), Atrial Flutter
Electrophysiological Registry Duesseldorf
This registry at University Hospital Düsseldorf collects retrospective and prospective (from 2019 onward) data on patients undergoing electrophysiological studies (EPS), catheter ablation, and electrical cardioversion.
- Conditions
- Atrial Fibrillation (AF), Atrial Flutter, Supraventricular Tachycardias, Ventricular Tachycardia (VT)
- Trial name
- NCT07196176
- Where
- Germany
- Volunteers
- 1,000 people
- Sponsor
- Heinrich-Heine University, Duesseldorf
Myocarditis, Premature Ventricular Contractions
Myocarditis Causing Premature Ventricular Contractions:Insights From the MAVERIC Registry
To assess potential link between unrecognized myocardial inflammation (myocarditis) and premature ventricular contractions (PVCs) associated with and without reduced Left ventricular ejection fraction (LVEF) through comprehensive…
- Conditions
- Myocarditis, Premature Ventricular Contractions, Ventricular Tachycardia (VT)
- Trial name
- MAVERIC (NCT05158751)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Ventricular Tachycardia (VT), Atrial Tachycardia
Clinical Study on the Efficiency of Rapid Arrhythmia Mapping Using EasyStars™ High Density Mapping Catheter Applications
The primary objective of this study was to evaluate the clinical feasibility, safety, and surgical characteristics of the EasyStars™ High Density Mapping Catheterin in patients with complex arrhythmias.
- Conditions
- Ventricular Tachycardia (VT), Atrial Tachycardia, Typical Atrial Flutter, Paroxysmal Atrial Fibrillation (PAF)
- Trial name
- Rapid Arrhythm (NCT07079813)
- Testing
- EasyStars™ High Density Mapping Catheter
- Volunteers
- 300 people
- Sponsor
- Shanghai MicroPort EP MedTech Co., Ltd.
Premature Ventricular Complexes, Ventricular Tachycardia (VT)
Transcutaneous Vagus Nerve Stimulation for Ventricular Arrhythmias
Ventricular arrhythmias are abnormal heart rhythms that arise from the bottom chambers of the heart. They can cause debilitating symptoms when they occur intermittently (these are called premature ventricular ectopics or PVCs)…
- Conditions
- Premature Ventricular Complexes, Ventricular Tachycardia (VT), Ventricular Arrhythmias
- Trial name
- TREAT-VT (NCT07026695)
- Testing
- transcutaenous vagal nerve stimulation
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- University College, London
Ventricular Tachycardia, Monomorphic, Ventricular Tachycardia, Sustained
Stereotactic Radiosurgery as Second-line Therapy for Ventricular Tachycardia
The aim of the study is to compare the efficacy and safety of treating recurrent sustained Ventricular Tachycardia (sVT) after prior Catheter Ablation (CA) in patients with Implanted Cardioverter-Defibrillator (ICD) between re-do…
- Conditions
- Ventricular Tachycardia, Monomorphic, Ventricular Tachycardia, Sustained, Ventricular Tachycardia (VT), Ventricular Tachycardia (V-Tach)
- Trial name
- STAR-4VT (NCT07017855)
- Testing
- Stereotactic Arrhythmia Radioablation (STAR), Catheter Ablation
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Silesia
Ventricular Tachycardia (VT)
Ventricular Tachycardia Ablation Through Radiation Therapy Consortium: Concept Description of an Observational Retrospective Multicentric Trial
Recurrent ventricular tachycardia (VT) is a potentially life-threatening arrhythmia in patients with structural heart disease. Despite the use of antiarrhythmic drugs, implantable cardioverter-defibrillators (ICDs), and…
- Trial name
- VT-ART R (NCT06990139)
- Where
- Italy
- Volunteers
- 149 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Ventricular Tachycardia (VT)
VT ART Consortium: Radioablation for Ventricular Tachycardia
The overall objective of the study is to evaluate the efficacy and safety of stereotactic radiation therapy in the non invasive ablation of ventricular tachycardia refractory to any other type treatment.
- Trial name
- VT-ART-P (NCT06922214)
- Testing
- Stereotactic Body Radiation Therapy (SBRT)
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Ventricular Tachycardia (VT), Premature Ventricular Contraction (PVC)
Computational Cardiac Imaging Analysis to Guide Ventricular Tachycardia Ablation Procedures (AI-VT)
The purpose of this study is to evaluate the clinical outcomes (clinical efficacy and safety) of using supplemental non-invasive computational ECG and cardiac imaging analysis tools to help guide ablation of ventricular…
- Conditions
- Ventricular Tachycardia (VT), Premature Ventricular Contraction (PVC), Ventricular Fibrillation
- Trial name
- AI-VT (NCT06964152)
- Testing
- Computational electrocardiography and cardiac computed tomography mapping
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of California, San Diego
Ventricular Tachycardia (VT)
Antiarrhythmics or Ablation for Ventricular Tachycardia 2
A multicenter, randomized clinical trial to assess whether catheter ablation or antiarrhythmic drug therapy provides the most effective control of important clinical outcomes for patients with prior myocardial infarction and…
- Trial name
- VANISH2 (NCT02830360)
- Testing
- Antiarrythmic Drug Therapy, Catheter ablation
- Where
- 22 sites in United States, Canada and 1 more
- Volunteers
- 416 people
- Sponsor
- John Sapp
Ischemic Ventricular Tachycardia (VT)
Paced Electrogram Feature Analysis (PEFA) for Ablation Targeting in Ischaemic Ventricular Tachycardia
Canadian multicentre prospective cohort study of 40 patients with ischaemic heart disease and therapy from an implantable cardioverter defibrillator (ICD).
- Trial name
- PEFA-VT (NCT03870854)
- Testing
- PEFA VT ablation technique
- Where
- 3 sites in Canada
- Volunteers
- 40 people
- Sponsor
- Dr. Damian Redfearn
Arrhythmia, Ventricular Tachycardia (VT)
A Study to Evaluate the Effect of Vagus Nerve Stimulation in Patients Undergoing VT Ablation
Vagus nerve stimulation (VNS) has been shown to be beneficial in multiple studies including heart failure. The goal of this clinical investigation is to gain additional information about how vagus nerve stimulation relates to…
- Trial name
- NCT04359004
- Testing
- Vagus Nerve Stimulation (VNS)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of California, Los Angeles
Ventricular Tachycardia (VT)
Pan-Asia United States PrEvention of Sudden Cardiac Death Catheter Ablation Trial
The current standard of care for ventricular tachycardia (VT) includes the use of medicine called anti-arrhythmic drugs (AADs) and Implantable Cardioverter Defibrillator (ICD) therapy.
- Trial name
- PAUSE-SCD (NCT02848781)
- Testing
- Implantable Cardioverter Defibrillator (ICD), Catheter Ablation
- Where
- 12 sites in United States, China and 3 more
- Volunteers
- 180 people
- Sponsor
- University of Arizona
Aortic Stenosis, Non-Sustained VT
Mechanisms of Excess Risk in Aortic Stenosis
Aortic stenosis (AS) is caused by narrowing of one of the main heart valves. Replacing the valve is the only treatment to prevent the heart from failing or death.
- Conditions
- Aortic Stenosis, Non-Sustained VT, Heart Failure
- Trial name
- MASTER (NCT04627987)
- Testing
- Cardiac MRI scan, Serum biomarkers (High sensitivity troponin, NT-proBNP, Implantable Loop Recorder
- Where
- United Kingdom
- Volunteers
- 192 people
- Sponsor
- University College, London
Chronic Systolic Heart Failure, Paroxysmal VT
Cardiac MRI for Optimal Heart Failure Outcomes With CRT Upgrades
This study will investigate the use of cardiac MRI in patients with standard ICDs and pacemakers to inform how cardiac resynchronization therapy (CRT) can best be implemented in these patient and which patients are the best…
- Trial name
- NCT03504891
- Testing
- MRI prior to CRT Upgrade, MRI prior to de novo CRT
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Virginia
Bacterial Vaginosis, HUDC_VT
Clinical Study to Evaluate the Efficacy of HUDC_VT in Patients With Bacterial Vaginosis
The objective of the study is to confirm the pharmacological mechanism and evaluate the efficacy and safety after HUDC-VT administration compared to placebo in patients with bacterial vaginosis.
- Conditions
- Bacterial Vaginosis, HUDC_VT, Haudongchun
- Trial name
- NCT03357666
- Testing
- HUDC_VT(Glucose 200mg/Sodium chloride 200mg), HUDC_VT (Glucose 400mg/Sodium chloride 200mg), HUDC_VT (Glucose 400mg)
- Where
- South Korea
- Volunteers
- 150 people
- Sponsor
- Haudongchun Co., Ltd.