Clinical trials: Uterine Injury
Thrombopenia, Cervical Cancer
Herombopag for the Prevention of Radio-chemotherapy Induced Thrombocytopenia in Cervical Cancer
Exploring and evaluating the efficacy of herombopag in preventing thrombocytopenia due to radiotherapy for cervical cancer
- Conditions
- Thrombopenia, Cervical Cancer, Radiotherapy Side Effect, Chemotherapeutic Toxicity
- Trial name
- NCT06745219
- Testing
- herombopag
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Peking University Cancer Hospital & Institute
Episiotomy Wound, Anemia
Use of Tranexamic Acid After Vaginal Delivery with Episiotomy a RCT Placebo Control Trail
The objective of this study is to assess the effect of TA treatment on decline in Hb levels following vaginal delivery with an episiotomy, compared to a control group not receiving TA.
- Conditions
- Episiotomy Wound, Anemia, Early Postpartum Hemorrhage, Hemoglobin
- Trial name
- NCT05448456
- Testing
- Tranexamic acid
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Obstetrical Complications, Monitoring Injury of Scalp of Newborn
Maternal-Fetal Monitoring by Connected Abdominal Patch - MOMA
During a previous clinical trial (RCF-abdo: 2018-A01194-51), trans-abdominal signals were collected in 90 patients at the maternity Jeanne de Flandre.
- Trial name
- MOMA (NCT05263427)
- Testing
- TOCONAUTE
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Lille
Infertility, Endometrial Diseases
Endometrial Injury In Recurrent Implantation Failure
The aim of this study is to investigate that the efficacy of the endometrial injury before IVF in recurrent implantation failure patients.
- Trial name
- NCT03748238
- Testing
- Endometrial Injury with Hysteroscopy
- Where
- Turkey (Türkiye)
- Volunteers
- 230 people
- Sponsor
- Gurgan Clinic
Cervical Cancer, Endometrial Cancer
Compliance to Vaginal Dilation Therapy in Patients Who Have Undergone Radiation Therapy For Stage IB, Stage IIA, Stage IIB, Stage IIIA, or Stage IIIB Cervical Cancer or Stage IA, Stage IB, Stage IIA, or Stage IIB Endometrial Cancer
RATIONALE: Understanding how well patients comply with their treatment regimen may help doctors determine best treatment and ongoing care for future patients.
- Conditions
- Cervical Cancer, Endometrial Cancer, Radiation Toxicity, Sexuality and Reproductive Issues
- Trial name
- NCT00735514
- Testing
- compliance monitoring, questionnaire administration, assessment of therapy complications
- Where
- 8 sites in United States
- Volunteers
- 83 people
- Sponsor
- Case Comprehensive Cancer Center
Cesarean Section, Repeated, Cesarean, Uterine Scar Thickness
Impact of Uterine Closure Techniques on the Cesarean Scar Thickness After Repeated Cesarean Section
We compares two techniques of uterine closure on myometrium thickness at the site of uterine scar of women who underwent repeated cesarean section.
- Conditions
- Cesarean Section, Repeated, Cesarean, Uterine Scar Thickness, Cesarean, Residual Myometrial Thickness, Cesarean Section Complications
- Trial name
- NCT03644433
- Testing
- Single layer closure, Double layer closure after resection uterine scar
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ataturk University
Pregnancy, Cesarean Section
Vaginal Birth After Caesarean Section - Effect on Maternal Psychosocial Function
The incidence of caesarean section has reached 15-20% in most developed countries. Encouraging vaginal birth after caesareans section (VBAC) has been considered a key component of a strategy to reduce the caesarean section rate.
- Conditions
- Pregnancy, Cesarean Section, Uterine Rupture
- Trial name
- NCT00517140
- Testing
- Repeat Caesaen section, vaginal delivery
- Where
- China
- Volunteers
- 262 people
- Sponsor
- Hospital Authority, Hong Kong
Operation Wound; Infection, Endometritis
Use of Antiseptic Solution for Vaginal Wash Before Cesarean Section
To evaluate the rate of infections after cesarean sections in patients with premature rupture of membranes after vaginal wash either with an antiseptic solution (clorhexidine solution) vs. saline solution (placebo).
- Trial name
- NCT03442218
- Testing
- Clorhexidine, Saline solution
- Where
- Panama
- Volunteers
- 203 people
- Sponsor
- Saint Thomas Hospital, Panama
Complications; Cesarean Section
Vaginal Cleansing Before Cesarean Delivery to Reduce Infection
The purpose of this study is to test the hypothesis that vaginal cleansing with povidone-iodine solution immediately prior to cesarean delivery reduces postcesarean infectious morbidity.
- Trial name
- NCT02495753
- Testing
- Vaginal Cleansing, Abdominal Cleansing
- Where
- United States
- Volunteers
- 608 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Triple Negative Breast Cancer, Diffuse Large B Cell Lymphoma
A Dose Escalation and Dose Expansion Study of Intratumoral ONM-501 Alone and in Combination With Cemiplimab in Patients With Advanced Solid Tumors and Lymphomas.
A phase 1, multicenter, open label, non-randomized dose escalation and dose expansion study to examine the maximum tolerated dose, (MTD), minimum effective dose (MED) and/or recommended dose for expansion (RDE) of intratumoral…
- Conditions
- Triple Negative Breast Cancer, Diffuse Large B Cell Lymphoma, Follicular Lymphoma, Lymphoma, Non-Hodgkin
- Trial name
- ON-5001 (NCT06022029)
- Testing
- ONM-501, Cemiplimab
- Where
- 16 sites in United States, Australia
- Volunteers
- 168 people
- Sponsor
- OncoNano Medicine, Inc.
Uterine Rupture, Mode of Delivery
Uterine Rupture During Labor Among Women With a Prior Cesarean Delivery
Although a rare event, uterine rupture during labour is one of the most serious obstetric complications because of the dramatic maternal-fetal consequences that can result.
- Trial name
- NCT04566705
- Testing
- Risks factors, maternal and neonatal outcomes/complications
- Where
- France
- Volunteers
- 95 people
- Sponsor
- University Hospital, Montpellier
Preterm Birth, Intra-uterine Growth Restriction
Consequences of Antiangiogenic Factors Involved in Preeclampsia on Intra-uterine Growth Restricted Preterm Newborn
Preeclampsia complicates about 2-7% of pregnancies and is a major contributor to maternal and neonatal morbidity and mortality worldwide.
- Conditions
- Preterm Birth, Intra-uterine Growth Restriction, Maternal Preeclampsia, Bronchopulmonary Dysplasia
- Trial name
- ANGIODYS (NCT01648855)
- Testing
- Biological samples
- Where
- France
- Volunteers
- 33 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Biopsy Wound, Endometrial Hyperplasia
Effect of Stress Ball Use on Anxiety Level During Endometrial Biopsy Procedure
The aim of this study is to determine the effect of stress ball application on the anxiety level during the endometrial biopsy procedure. This research is planned as a randomised controlled study.
- Conditions
- Biopsy Wound, Endometrial Hyperplasia, Endometrial Neoplasms
- Trial name
- NCT06171581
- Testing
- stress ball, control
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Zonguldak Bulent Ecevit University
Cesarean Section Complications
Vertical Splitting of Muscle Layer in Lower Segment Cesarean Sections to Avoid Uterine Vessels Injury
Cesarean section is one of the oldest surgical interventions in the history of medicine.Many variations in cesarean section technique have been studied.The investigatory team are aiming to decrease blood loss during cesarean…
- Trial name
- NCT03224247
- Testing
- Transverse cutting, vertical splitting
- Where
- Egypt
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cervical Cancer, Radiotherapy Side Effect
Circadian as A Prognostic Factor For Radiation Response in Cervical Cancer
The study was a Randomized Clinical Trial (RCT) or clinical trial comparing the results of radiation treatment of 2 treatment groups, i.e.
- Trial name
- NCT05511740
- Testing
- Afternoon Radiation
- Volunteers
- 71 people
- Sponsor
- Universitas Indonesia
Leiomyoma, Uterine, Liver Injury
Liver Safety Assessment During Ulipristal Acetate Treatment for Uterine Fibroids (LISA)
Uterine fibroids are are the most common gynecological tumor. Among the pharmacological treatment options, ulipristal acetate (UPA) has proven to be effective in control of bleeding and reduction of size of fibroids.
- Conditions
- Leiomyoma, Uterine, Liver Injury, Treatment Side Effects
- Trial name
- LISA (NCT04004884)
- Testing
- Ulipristal Acetate
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
C.Delivery; Penetration, Pregnant Uterus, by Instrument, Obesity
Cesarean Wound Closure in Women With BMI 40 or Greater
The purpose of this randomized controlled prospective trial is to guide physicians on the most effective evidenced based skin closure during a cesarean section for the obese gravida, defined as a BMI of 40 or greater.
- Trial name
- NCT02549131
- Testing
- Randomizing to Suture or Staple closure of Cesarean section
- Where
- 2 sites in United States
- Volunteers
- 232 people
- Sponsor
- Pediatrix
ALS, Amyotrophic Lateral Sclerosis
NYSCF Scientific Discovery Biobank
The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate diverse disease research using cells from the body (such as skin or blood cells) to make stem cells and other types of cells…
- Conditions
- ALS, Amyotrophic Lateral Sclerosis, Alzheimer Disease, Alzheimer Disease, Early Onset
- Trial name
- NCT06203106
- Testing
- Biological Sample Collection
- Where
- United States
- Volunteers
- 10,000 people
- Sponsor
- New York Stem Cell Foundation Research Institute
Cesarean Section Complications
Effect of Autologous Platelet-rich Plasma in Uterine Wound Healing
The aim of this study is to evaluate the efficacy of intramuscular autologus platelet rich plasma on uterine wound healing after primary cesarean section
- Trial name
- NCT03497325
- Testing
- autologus platelet rich plasma
- Where
- Egypt
- Volunteers
- 134 people
- Sponsor
- Ain Shams University
Cesarean Section, Wound Dehiscence
A New Technique for Uterine Incision Closure at The Time of Cesarean Section: Does it Make a Difference
The purpose of this study was to compare the short term operative outcomes of three different surgical techniques for uterine incision closure during cesarean section (CS).
- Trial name
- NCT04681378
- Testing
- double layer step up-step down technique
- Volunteers
- 120 people
- Sponsor
- Menoufia University