Clinical trials: Urinary Tract Stone Surgery
Stone, Kidney
Endoscopic Combined Intrarenal Surgery Versus Multi-Tract Percutaneous Nephrolithotomy for Complex Renal Stones:
The aim of this study is to compare outcomes of endoscopic combined intrarenal surgery (ECIRS) with the multi-tract percutaneous nephrolithotomy for management of complex renal stones.
- Trial name
- NCT05460559
- Testing
- Group A (p-PCNL) procedure, Group B (s-ECIRS) procedure
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Mansoura University
Kidney Stone
SEARCH FOR OPTIMAL ANAESTHESIA IN RETROGRADE INTRARENAL SURGERY
Patients undergoing retrograde intrarenal surgery for kidney stones from November 2017 to May 2018 were prospectively recruited to participate in the study.
- Trial name
- NCT03999255
- Testing
- combined respiratory support (CRS)
- Where
- Russia
- Volunteers
- 38 people
- Sponsor
- St. Petersburg State Pavlov Medical University
Kidney Calculi, Radiation Exposure
Safety and Efficacy of Fluoroscopy-free Technique During Retrograde Intrarenal Surgery for Renal Stones
Aiming to reduce radiation exposure to patients and physicians, the investigators conduct this study protocol to evaluate the possibility of performing retrograde intrarenal surgery (RIRS) under direct visualization without…
- Conditions
- Kidney Calculi, Radiation Exposure, Retrograde Intrarenal Surgery
- Trial name
- NCT05269108
- Testing
- Fluoroscopy-free RIRS, Standard RIRS
- Where
- Egypt
- Volunteers
- 503 people
- Sponsor
- Al-Azhar University
Stone, Kidney, Lithiasis Renal
Standard-PCNL vs Mini-PCNL vs Super-mini PCNL for the Treatment of ≥2 cm Renal Stone
Background: Standard-PCNL was considered as the first choice for ≥2 cm renal stones. Miniaturized technique Mini-PCNL has also been implicated in the past two decades.
- Conditions
- Stone, Kidney, Lithiasis Renal, Surgery
- Trial name
- NCT03771365
- Testing
- Standard-PCNL, Mini-PCNL, SMP
- Volunteers
- 3,000 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Kidney Stone, Retrograde Intrarenal Surgery (RIRS)
Multimodal Opioid-Free Anesthesia in RIRS
The goal of this clinical trial is to evaluate whether a dexmedetomidine-ketamine based opioid-free anesthesia (OFA) protocol can provide effective analgesia compared to conventional fentanyl-based anesthesia in adult patients…
- Conditions
- Kidney Stone, Retrograde Intrarenal Surgery (RIRS), Postoperative Pain
- Trial name
- NCT07636070
- Testing
- Dexmedetomidine-Ketamine Opioid-Free Anesthesia, Fentanyl-Based Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- murat sahin
Kidney Calculi, Renal Calculi
Sheathless, Traditional, and Suction Access Sheath RIRS for Renal Stones ≤2 cm
This completed randomized clinical study was designed to compare three different techniques of retrograde intrarenal surgery (retrograde intrarenal surgery) for the treatment of kidney stones that are 2 centimeters or smaller.
- Conditions
- Kidney Calculi, Renal Calculi, Urolithiasis, Nephrolithiasis
- Trial name
- NCT07289230
- Testing
- Traditional ureteral access sheath retrograde intrarenal surgery, Suction ureteral access sheath retrograde intrarenal surgery, Sheathless retrograde intrarenal surgery
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Urolithiasis
Differences in Urine NGAL Levels in Patients Undergoing RIRS With or Without Ureteral Access Sheath
This study will include patients aged between 18 and 65 who will undergo retrograde infrarenal surgery (RIRS) due to renal stone(s).
- Trial name
- NCT02485002
- Testing
- RIRS with ureteral access sheath, RIRS without ureteral access sheath
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Selcuk University
Postoperative Pain Management, Urolithiasis
The Use of Intranasal Ketoralac for Pain Management (Sprix)
Despite an overall reduction in the perioperative complication rate, post operative pain management after ureteroscopic removal of stones (URS) remains a major factor delaying discharge of patients.
- Trial name
- NCT01736358
- Testing
- Intranasal Ketoralac
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Montefiore Medical Center
Urinary Stone
Results of Safety Guidewire Use in Ureteroscopic Stone Surgery
Up-to-date, urology guidelines introduce safety guidewire (SGW) as an integral tool in ureteroscopy and recommended its routine use.
- Trial name
- NCT03108053
- Testing
- Semirigid Ureteroscopy (URS) With Guide Wire, Semirigid Ureteroscopy (URS) Without Guide Wire
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people
- Sponsor
- Marmara University
Kidney Stones, Nephrolithiasis
Comparison of Different Ventilation Modes for Reducing Kidney Motion During Retrograde Intrarenal Surgery
This randomized clinical trial will compare four ventilation strategies during retrograde intrarenal surgery performed under general anesthesia.
- Trial name
- RIRS-VENT (NCT07705646)
- Testing
- Standard Ventilation, Hypoventilation, Intermittent Apnea Ventilation
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey
Urolithiasis, Kidney Calculi
Human Voice vs AI-Cloned Voice Audio Added to Written Consent Before Ureteroscopy or Retrograde Intrarenal Surgery (AUDIO-CONSENT)
Before kidney stone surgery with a flexible or semirigid ureteroscope, patients must read and sign a written consent form, but many patients find these forms long and hard to understand.
- Conditions
- Urolithiasis, Kidney Calculi, Ureteral Calculi, Informed Consent
- Trial name
- AUDIO-CONSENT (NCT07859436)
- Testing
- Standard written informed consent, Human-voice audio consent recording, AI-cloned-voice audio consent recording
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Aydin Adnan Menderes University
Kidney Stones, Urolithiasis
Evaluation of Stone Composition in Surgical Kidney Stone Patients in Vietnam
This is a prospective observational study conducted at Binh Dan Hospital, Ho Chi Minh City, Vietnam, from July to December 2023.
- Conditions
- Kidney Stones, Urolithiasis, Nephrolithiasis
- Trial name
- STONE-VN (NCT07038954)
- Testing
- Stone Composition Analysis
- Where
- Vietnam
- Volunteers
- 222 people
- Sponsor
- Binh Dan Hospital
Retrograde Intrarenal Surgery, Stone, Kidney
Homework in Retrograde Intrarenal Surgery
To evaluate the effectiveness of this homework on stone clearance rates after retrograde intrarenal surgery (RIRS) by instructing the patient in the home environment and suggesting percussion and movement/position changes to…
- Trial name
- NCT06795256
- Testing
- Percussion and position change in retrograde intrarenal surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Adiyaman University
Kidney Calculi
Effect of Anesthesia Type on Surgeon Workload During Endoscopic Kidney Stone Surgery
This prospective observational study aims to evaluate the association between anesthesia type and surgeon-perceived workload and surgical ergonomics in adult patients undergoing flexible ureteroscopy and retrograde intrarenal…
- Trial name
- RIRS-ERG (NCT07763600)
- Testing
- General Anesthesia (GA), Spinal Anesthesia (SA)
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Malatya Governor Research Hospital
Bariatric Surgery Candidate, Kidney Stone
GI Oxalate Absorption
This study aims to learn more about how oxalate, a compound found in many foods, may affect a person's chances of forming kidney stones. Active participation in this study will last for around one week.
- Trial name
- NCT05356000
- Testing
- Special low-oxalate diet followed by all-day visit to University of Chicago research clinic
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Chicago
Urinary Calculi
Endoscopic Combined Intrarenal Surgery vs. Percutaneous Nephrolithotomy for Treatment of Staghorn Calculi
This is a prospective randomized study to compare endoscopic combined intrarenal surgery and PCNL as modalities of treatment for staghorn stones. In terms of efficacy and safety
- Trial name
- NCT06519812
- Testing
- Combined Intrarenal Surgery and percutaneous nephrolithotomy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University
Renal Stone
Comparison of Surgical Outcomes Between MPCNL and RIRS
The objective of this research is to investigate the surgical outcomes of minimally invasive percutaneous nephrolithotomy(MPCNL) and retrograde intrarenal surgery (RIRS)for patients with renal stone larger than 1cm.
- Trial name
- NCT02067221
- Testing
- RIRS, MPCNL
- Where
- South Korea
- Volunteers
- 70 people
- Sponsor
- Seoul National University Hospital
Renal Calculi
Cost-Effectiveness of Different Treatment Options for Lower Calyceal Stones
The aim of the present study to perform a full cost analysis for the complete clearance of calyceal stones by retrograde intrarenal surgery (RIRS) and percutaneous nephrolithotomy (PNL) for the treatment of lower calyceal stones…
- Trial name
- NCT03614247
- Testing
- Retrograde intrarenal surgery, Micro-PNL, Ultra-mini PNL
- Volunteers
- 175 people
- Sponsor
- Ankara Training and Research Hospital
Colorectal Carcinoma, Rectal Prolapse
Prospective Evaluation of Cornerstone Robotics Sentire Surgical System in Major Gastrointestinal and Urologic Surgery
Robotic assisted surgery has been performed for more than two decades with good success and safety profile. However, there was only one dominating robotic surgical system available in the past which led to high cost for robotic…
- Conditions
- Colorectal Carcinoma, Rectal Prolapse, Prostate Cancer (Adenocarcinoma), Bladder Cancer
- Trial name
- NCT06926374
- Testing
- Robotic surgery using the Sentire Surgical System
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Chinese University of Hong Kong
Kidney Stones
Comparison of Multiple-, Single- and Zero-dose of Ciprofloxacin Prophylaxis in Retrograde Intrarenal Surgery
The purpose of this study is to compare the postoperative systemic inflammatory response syndrome (SIRS) rates undergoing retrograde intrarenal surgery (RIRS) after multiple-, single-, zero-dose of ceftriaxone prophylaxis in a…
- Trial name
- RIRS (NCT02304822)
- Testing
- Multiple-dose of Ciprofloxacin prophylaxis, Single-dose of Ciprofloxacin prophylaxis, Zero-dose of Ciprofloxacin prophylaxis
- Where
- China
- Volunteers
- 450 people
- Sponsor
- Guohua Zeng