Clinical trials: Urinary Incontinence,Stress, open to volunteers
Urinary Incontinence, Urinary Bladder Overactive
Does Use of a Pre-Procedure Educational Video for Urodynamic Testing Reduces Anxiety?
The objective of this randomized prospective study is to evaluate whether viewing an educational video before urodynamic testing reduces anxiety among women undergoing evaluation for pelvic floor or urinary symptoms.
- Conditions
- Urinary Incontinence, Urinary Bladder Overactive, Urinary Incontinence , Stress
- Trial name
- VIDEO-U (NCT07740629)
- Testing
- video
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Yair Daykan
Stress Urinary Incontinence
Effectiveness and Cost-effectiveness of PelviSense, a Novel Biofeedback Device for Stress Urinary Incontinence in Women
Aims: (1) Investigate the efficacy of PelviSense-assisted PFMT compared with PFMT alone for improving SUI symptom severity in women; (2) Compare the cost-effectiveness of the PelviSense device against PFMT alone for treating SUI…
- Trial name
- NCT05627726
- Testing
- PelviSense-assisted pelvic floor muscle training group, Active comparator
- Where
- 2 sites in Hong Kong
- Volunteers
- 142 people
- Sponsor
- The Hong Kong Polytechnic University
Urinary Incontinence
Prospective and Comparative Evaluation of a Medical Device Composed of a Perineal Probe Connected to a Mobile Application in the Management of Stress Urinary Incontinence.
Stress urinary incontinence (SUI) affects around 40% of women and has a major impact on quality of life. The gold standard for the treatment of SUI is pelvicfloor rehabilitation, but this presents constraints in terms of…
- Trial name
- PRIME (NCT06285292)
- Testing
- EMY
- Where
- France
- Volunteers
- 138 people
- Sponsor
- Nantes University Hospital
Stress Urinary Incontinence
Observational Registry for Iltamiocel Compared to Placebo for Urinary Sphincter Repair in Post-surgical Female Stress Incontinence
The main purpose of this registry is to collect observational, long-term safety and effectiveness data in subjects who have received at least one dose of iltamiocel as part of the CLBT clinical study.
- Trial name
- CLBT RGST (NCT06743620)
- Testing
- iltamiocel
- Where
- United States
- Volunteers
- 96 people
- Sponsor
- Cook MyoSite
Stress Urinary Incontinence (SUI)
PFU vs. UDS in SUI
The goal of this observational stury is to test the diagnostic accuracy of Pelvic Floor Ultrasound in evaluating women with stress urinary incontinence compared to the reference standard Urodynamic Studies.
- Trial name
- UDS - PFU (NCT06886997)
- Testing
- Pelvic Floor Ultrasound, Urodynamic studies
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Stress Urinary Incontinence
Efficacy/Safety of Midurethral Sling
The trans-obturator tape (TOT), which exhibits a satisfactory cure rate and a relatively diminished invasiveness, has been increasingly accepted as a surgical treatment of stress urinary incontinence (SUI) patients.
- Trial name
- NCT05255289
- Testing
- Urodynamic investigations before and after a trans-obturator tape protocol., Urodynamic investigations before and after a tension-free vaginal tape-obturator (TVT-O), Urodynamic investigations before and after a mini Arc protocol.
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- Mackay Medical College
Stress Urinary Incontinence
MoVo-guided Traditional Chinese Kegel Exercises for Preventing Postpartum Urinary Incontinence.
The goal of this clinical trial is to determine whether a prenatal exercise program integrating Liuzijue qigong with traditional levator ani training, guided by the MoVo (Motivation-Volition) theory and delivered via a supervised…
- Trial name
- NCT07742202
- Testing
- Routine Verbal Instruction Group, App-Supervised Kegel Exercise Group, Liuzijue & Levator Ani Training Group
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Yu xin Qian
Urinary Incontinence,Stress
A Study of Orforglipron in Female Participants With Stress Urinary Incontinence Who Have Obesity or Overweight
The GZPS master protocol will support two independent studies, J2A-MC-GZS1 and J2A-MC-GZS2. Each study will see how well and safely orforglipron works in adult female participants with stress urinary incontinence (SUI) who have…
- Trial name
- RESTRAIN-SUI (NCT07202884)
- Testing
- Orforglipron
- Where
- 120 sites in United States, Canada and 7 more
- Volunteers
- 1,000 people
- Sponsor
- Eli Lilly and Company
Urinary Incontinence,Stress
Synchronous and Asynchronous Telerehabilitation for Women With Urinary Incontinence
In the adult female Greek population,approximately 27% suffer from urinary incontinence (UI). Nowadays, the conservative, evidence-based and 'gold standard' therapy of UI involves pelvic floor muscles (PFM) training programs…
- Trial name
- NCT06848517
- Testing
- BSATP Group, FtFS Group, Control Group (CG)
- Where
- Greece
- Volunteers
- 60 people
- Sponsor
- University of Patras
Stress Urinary Incontinence (SUI), Dynamic Neuromuscular Stabilization
Dynamic Neuromuscular Stabilization vs Pelvic Floor Muscle Training in Women With Stress Urinary Incontinence
This randomized controlled trial aims to compare the pre- and post-treatment effects of Dynamic Neuromuscular Stabilization (DNS) training and Pelvic Floor Muscle Training (PFMT) on pelvic floor muscle function, pelvic floor…
- Conditions
- Stress Urinary Incontinence (SUI), Dynamic Neuromuscular Stabilization, Pelvic Floor Muscle Training, Muscle Morphology
- Trial name
- DYNA-SUI (NCT07075900)
- Testing
- Dynamic Neuromuscular Stabilization Training, Pelvic Floor Muscle Training
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Izmir Katip Celebi University
Prostate Cancer (Post Prostatectomy)
The Application of Somatosensory Interactive Pelvic Floor Muscle Training for Stress Urinary Incontinence in Men Underwent Radical Prostatectomy
The study aims to compare the efficacy of different pelvic floor muscle training (PFMT) modes on improving urinary incontinence (UI) recovery in prostate cancer (PCa) patients after radical prostatectomy (RP).
- Trial name
- NCT06740071
- Testing
- somatosensory interactive pelvic floor muscle training, pelvic floor magnetic stimulation therapy, standard pelvic floor muscle training
- Where
- 2 sites in China, Hong Kong
- Volunteers
- 100 people
- Sponsor
- The University of Hong Kong
Pelvic Organ Prolapse Vaginal Surgery, Stress Urinary Incontinence in Women
The AMPER Study: Evaluation of the Efficacy of Human Amniotic Membrane Grafting in Preventing Mesh Exposure in Vaginal Reconstructive Surgery Using Polypropylene Mesh.
This study evaluates the efficacy of adding a human amniotic membrane graft to polypropylene mesh surgery for pelvic prolapse and stress urinary incontinence.
- Trial name
- AMPER (NCT07414849)
- Testing
- Sacrospinous Hysteropexy with Mesh, Retropubic Mid-urethral Sling (Bottom-Up), Transobturator Mid-urethral Sling (Out-In)
- Where
- Argentina
- Volunteers
- 330 people
- Sponsor
- Hospital General de Agudos J. M. Penna
Stress Urinary Incontinence
Peri-Urethral Platelet-Rich Plasma Injections for Postmenopausal Female Stress Urinary Incontinence
his prospective interventional study will evaluate the effectiveness and safety of peri-urethral injections of platelet-rich plasma for treating stress urinary incontinence in postmenopausal women.
- Trial name
- NCT07807982
- Testing
- Autologous Platelet-Rich Plasma
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Benha University
Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI)
Suzetrigine for Opioid-Sparing Postoperative Analgesia Following Transvaginal Pelvic Reconstructive Surgery
Suzetrigine is a selective NaV1.8 inhibitor that provides peripheral analgesia without opioid-related CNS effects. This single-center stepped-wedge randomized clinical trial evaluates whether a suzetrigine-based postoperative…
- Conditions
- Pelvic Organ Prolapse (POP), Stress Urinary Incontinence (SUI), Postoperative Pain
- Trial name
- NCT07600697
- Testing
- Suzetrigine, Opioid Analgesics (Tramadol or Oxycodone), Scheduled Acetaminophen and Ibuprofen
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- University of California, Los Angeles
Urinary Incontinence,Stress, Stress Urinary Incontinence
Synchronized Core-Pelvic Floor Activation in Urinary Incontinence
This study aims to investigate whether co-activation of the pelvic floor and core muscles improves treatment outcomes in individuals with urinary incontinence.
- Conditions
- Urinary Incontinence,Stress, Stress Urinary Incontinence, Mixed Incontinence Due to Prolapse of Female Genital Organ, Urinary Incontinence
- Trial name
- NCT07387640
- Testing
- Conventional Pelvic Floor Muscle Training, Pelvic Floor and Core Muscle Co-activation Training
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Bezmialem Vakif University
Urinary Incontinence , Stress
Pilot Study of the ARTUS® Artificial Urinary Sphincter on Women
The subjects will be implanted with the ARTUS® medical device and then be followed up to 2 years post-implantation, with the primary endpoints measured at 3-month post-implantation.
- Trial name
- SPHIN-X (NCT07641218)
- Testing
- Artificial Urinary Sphincter ARTUS
- Where
- 2 sites in France
- Volunteers
- 6 people
- Sponsor
- Myopowers Medical Technologies France SAS
Urinary Incontinence (UI), Pelvic Floor Disorders
Pelvic Floor Muscle Training and Neuromuscular Performance in Women's Rugby
This randomized controlled trial will evaluate whether a rugby-tailored pelvic floor muscle training programme reduces urinary incontinence symptoms and influences neuromuscular performance in professional and semi-professional…
- Trial name
- NCT07757633
- Testing
- Rugby-Tailored Pelvic Floor Muscle Training Programme
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Benign Prostatic Hyperplasia, Benign Prostatic Obstruction
Anterior Bridge-Preserving Versus Conventional Early Apical Release During Holmium Laser Enucleation of the Prostate
Holmium laser enucleation of the prostate (HoLEP) is an effective operation for men with urinary obstruction caused by a benign enlarged prostate. Some men leak urine for a period after the operation.
- Conditions
- Benign Prostatic Hyperplasia, Benign Prostatic Obstruction, Stress Urinary Incontinence, Lower Urinary Tract Symptoms (LUTS) in Men With Benign Prostatic Hyperplasia (BPH)
- Trial name
- ABPS-EAR-HOLEP (NCT07892599)
- Testing
- Anterior Bridge-Preserving Semicircular Early Apical Release (ABP-S-EAR), Conventional Early Apical Release (EAR)
- Volunteers
- 230 people
- Sponsor
- Ahmed Ebrahim Zahran
Stress Urinary Incontinence, Urinary Incontinence
Trial of Transurethral Bulking Agent Injection Versus Single-Incision Sling for Stress Urinary Incontinence
This is a multicentered, double-blind, randomized controlled, surgical trial of 358 women with inadequate symptom relief of stress urinary incontinence (SUI) or stress predominant mixed urinary incontinence (MUI) after…
- Conditions
- Stress Urinary Incontinence, Urinary Incontinence, Mixed Urinary Incontinence
- Trial name
- BASIS (NCT06480227)
- Testing
- Solyx Single-incision Sling, Bulkamid Transurethral Bulking Agent
- Where
- 7 sites in United States
- Volunteers
- 358 people
- Sponsor
- NICHD Pelvic Floor Disorders Network
Stress Urinary Incontinence (SUI)
Long-term Evaluation of the I-STOP Sling in Stress Urinary Incontinence Treatment
Evaluate quality of life and rate of reoperation after implantation of the I-STOP sling for stress urinary incontinence
- Trial name
- VIGI-ISTOP (NCT06665698)
- Volunteers
- 500 people
- Sponsor
- DILO Medical