Clinical trials: Urinary
Kidney Stones, Nephrolithiasis
Comparing Efficiency and Stone-Free Rates Mini PCNL vs Flex URS
The objective of the study is to compare the stone free rates with ureteroscopy utilizing the ClearPETRA suction ureteral access sheath, and mini-PCNL; both procedures and ClearPETRA sheaths are standard of care and are used…
- Conditions
- Kidney Stones, Nephrolithiasis, Urolithiasis
- Trial name
- NCT07072598
- Testing
- ClearPETRA suction access sheath
- Where
- United States
- Sponsor
- Northwestern University
Lower Urinary Tract Symptoms, Skeletal Muscle
Examining the Relationship Between Core Muscles and Bladder Issues in Children
The goal of this observational study is to learn about functional bladder problems in children. The main questions it aims to answer are: Does bladder symptoms in children have an effect on core muscles? How do core muscles…
- Trial name
- NCT06317116
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Izmir Bakircay University
Cystinuria
TCUPS- Tolvaptan Use in Cystinuria and Urolithiasis: A Pilot Study
The goal of this research project is to establish that in short-term use, tolvaptan is a safe and potentially effective new therapy for cystinuria, by conducting a short-term pilot study of the safety and tolerability of this…
- Trial name
- TCUPS (NCT02538016)
- Testing
- Tolvaptan
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Caleb Nelson
Urinary Stress Incontinence
TVT-ABBREVO Versus SERASIS for the Treatment of Female Urinary Stress Incontinence: 1 Year Outcomes of a Comparative Study With 2 Trans-obturator Sub Mid Urethral Slings
Abstract: Urinary Stress Incontinence (USI)- is a discomforting condition that negatively affects the quality of life of many female individuals and frequently treated by surgical intervention.
- Trial name
- NCT02867748
- Testing
- TVT-Abbrevo, Serasis
- Where
- 2 sites in Israel
- Volunteers
- 99 people
- Sponsor
- Western Galilee Hospital-Nahariya
Urothelial Cancer, Bladder Cancer
A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies
Background: Tumors in the genitourinary tracts can occur in the kidney, bladder, prostate, and testicles and can have common and rare histologies. Some cancers that occur along the genitourinary (GU) tract are rare.
- Conditions
- Urothelial Cancer, Bladder Cancer, Genitourinary Cancer, Urogenital Neoplasms
- Trial name
- NCT04923178
- Where
- United States
- Volunteers
- 1,100 people
- Sponsor
- National Cancer Institute (NCI)
Recurrent Bladder Urothelial Carcinoma, Recurrent Renal Pelvis Urothelial Carcinoma
Erlotinib Hydrochloride in Treating Participants With Muscle Invasive or Recurrent Urothelial Cancer
This phase II trial studies how well erlotinib hydrochloride works in Treating participants with muscle invasive urothelial cancer or urothelial cancer that has come back.
- Conditions
- Recurrent Bladder Urothelial Carcinoma, Recurrent Renal Pelvis Urothelial Carcinoma, Recurrent Ureter Urothelial Carcinoma, Recurrent Urethral Urothelial Carcinoma
- Trial name
- NCT00749892
- Testing
- Erlotinib Hydrochloride
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- M.D. Anderson Cancer Center
Prostatic Hyperplasia of the Medial Lobe
Rezum for 30-80ml Patients With Moderate-severe LUTS to Study Surgical Principles for Median Lobe Enlargement
This study was created to determine the safety and efficacy of treating prostatic hyperplasia with or without prominent median lobe enlargement with the REZUM technique.
- Trial name
- NCT06177821
- Testing
- Rezum®
- Where
- South Korea
- Volunteers
- 44 people
- Sponsor
- Seoul National University Hospital
Overactive Bladder
Risk Factors for Treatment Failure in Women With Detrusor Overactivity Receiving Combined Pharmacotherapy
This study evaluated the outcomes of women with detrusor overactivity treated with combined pharmacotherapy to identify risk factors for treatment failure.
- Trial name
- NCT07337252
- Testing
- Combined pharmacotherapy
- Where
- Taiwan
- Volunteers
- 61 people
- Sponsor
- Mackay Memorial Hospital
Bladder Outlet Obstruction, Lower Urinary Tract Symptoms
The Value of Multiple Urine Flow Rate Measurements in Male Benign Prostatic Hyperplasia (BPH) Subjects
Crossover comparison of different flow meters with a digital home flow meter as a reference. Main hypothesis: Reapeated home flow measurements with a disposable device will provide a better understanding of the patients urinary…
- Trial name
- NCT00710749
- Testing
- Disposable device, Digital device, Clinic flow measurement
- Where
- 4 sites in United States, Netherlands and 2 more
- Volunteers
- 60 people
- Sponsor
- Wellspect HealthCare
Sexual Activity
Female Sexual Function After Cystectomy
Cystectomy with bladder replacement, with or without urinary diversion, is the preferred treatment option for benign pathologies responsible for neurogenic bladder or sphincter dysfunction after failure of conservative…
- Trial name
- FSFAC (NCT04592848)
- Testing
- Questionnaires
- Where
- France
- Volunteers
- 36 people
- Sponsor
- Hospices Civils de Lyon
Nephrolithiasis
Percutaneous Nephrolithotomy: A Registry and Database
Kidney stones vary in size from a tiny grain of sand to as large as filling the inside of the kidney. Treatment decisions depend on the size, location, and composition of the stone.
- Trial name
- NCT00159393
- Testing
- registry and database
- Where
- 2 sites in United States
- Volunteers
- 1,697 people
- Sponsor
- Indiana Kidney Stone Institute
Urinary Incontinence
Quality of Life Among Hungarian Women with Urinary Incontinence
The aim of this study is to assess the prevalence of urinary incontinence among Hungarian women. In addition to that, we aim evaluate the health related quality of life among Hungarian women with urinary incontinence and to…
- Trial name
- NCT05618184
- Where
- Hungary
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Pecs
Lung Diseases, ERAS
Minimally Invasive Lung Surgery Under ERAS With Completely Tubeless Protocol Compared With That With Partially Tubeless Protocol
Previous studies have shown the feasibility of ERAS on minimally invasive lung surgery, but it is unknown whether completely tubeless protocol is safe and better.
- Conditions
- Lung Diseases, ERAS, Surgery
- Trial name
- NCT05269784
- Testing
- Minimally Invasive Lung Surgery Under ERAS With Completely Tubeless Protocol, Minimally Invasive Lung Surgery Under ERAS With partially Tubeless Protocol
- Where
- China
- Volunteers
- 600 people
- Sponsor
- The Second Hospital of Shandong University
Urinary Tract Infections in Children
7-day Compared With 10-day Antibiotic Treatment for Febrile Urinary Tract Infections in Children
The investigators aim to assess the effectiveness of a 7-day compared with a 10-day course of antibiotic treatment for febrile urinary tract infections (UTIs) in children.
- Trial name
- NCT03221504
- Testing
- Longer therapy duration, Shorter therapy duration
- Where
- 2 sites in Poland
- Volunteers
- 221 people
- Sponsor
- Medical University of Warsaw
Pneumonia, Blood Stream Infection
Optimizing Clinical Use of Polymyxin B
Polymyxin B is already being used extensively in the USA and other parts of the world; its use is likely to rapidly increase due to the greater burden of infections caused by MDR Gram-negative bacteria and the growing awareness…
- Conditions
- Pneumonia, Blood Stream Infection, Urinary Tract Infections, Respiratory Tract Infection (Including Tracheobronchitis)
- Trial name
- NCT02682355
- Where
- 6 sites in United States, Brazil and 1 more
- Volunteers
- 155 people
- Sponsor
- Rutgers, The State University of New Jersey
Inguinal Hernias
Urinary Catheterization Versus No Catheterization in Laparoscopic Total Extraperitoneal Inguinal Hernia Repair
The goal of this randomized controlled clinical trial is to determine whether avoiding routine urinary catheterization reduces postoperative urinary symptoms in patients undergoing laparoscopic totally extraperitoneal (TEP)…
- Trial name
- TEP-CAT (NCT07886814)
- Testing
- Routine Urinary Catheterization, No Routine Urinary Catheterization
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Ugur Duman
Hospital Infection, Urinary Tract Infections
The Global Prevalence of Infections in Urology Study
Urology departments from all over the world are invited to join the Global Prevalence Study on Infections in Urology (GPIU-study) and the GPIU Prostate Biopsy Side Study.
- Trial name
- GPIU (NCT03665467)
- Where
- 4 sites in Germany, Hungary and 2 more
- Volunteers
- 2,000 people
- Sponsor
- European Association of Urology Research Foundation
Urinary Bladder, Overactive, Pelvic Organ Prolapse
Study of Overactive Bladder in Women With Prolapse
Pelvic organ prolapse (POP) is a common problem. Symptoms of overactive bladder (OAB) are present in approximately 50% of patients with POP.
- Trial name
- SOAP (NCT01540214)
- Testing
- Pre- and postoperative evaluations
- Where
- Netherlands
- Volunteers
- 100 people
- Sponsor
- Radboud University Medical Center
Complicated Urinary Tract Infection, Acute Pyelonephritis
Study of Cefepime-zidebactam (FEP-ZID) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP)
This is a Phase 3, randomized, double-blind, multicenter, non-inferiority study to evaluate the efficacy, safety, and tolerability of FEP-ZID vs. meropenem in the treatment of hospitalized adults with cUTI or AP.
- Trial name
- NCT04979806
- Testing
- Cefepime-zidebactam (FEP-ZID), Meropenem
- Where
- 48 sites in United States, Bulgaria and 7 more
- Volunteers
- 530 people
- Sponsor
- Wockhardt
Overactive Bladder
Composur: Study to Understand the Performance of Vibegron in Participants with Overactive Bladder (OAB)
This study will evaluate the treatment satisfaction, discontinuation, reasons for discontinuation, quality of life, healthcare resource utilization, and safety with Vibegron for the treatment of OAB in the context of real-world…
- Trial name
- NCT05067478
- Testing
- Vibegron
- Where
- 64 sites in United States
- Volunteers
- 403 people
- Sponsor
- Urovant Sciences GmbH