Clinical trials: Urethral Stricture
Urethral Stricture
Dorsal vs. Ventral Buccal Graft Dorsal vs. Ventral Buccal Graft
This is a randomized non-blinded comparison of dorsal vs. ventral approach for buccal mucosa graft urethroplasty in the bulbar urethra. Buccal mucosa graft is a common method of repairing the strictured urethra.
- Trial name
- DoVeBuG (NCT02551783)
- Testing
- Urethroplasty with buccal mucosa graft, Ventral Buccal
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Minnesota
Urethral Stricture
Functional Outcome of Urethral Reconstructive Surgery
The analysis of the long-term outcomes and quality-of-life parameters after urethral reconstruction surgery.
- Trial name
- NCT01982136
- Testing
- end-to-end urethroplasty, substitution urethroplasty (buccal mucosa), substitution urethroplasty (pedicled skin flap)
- Where
- Belgium
- Volunteers
- 175 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Urethral Stricture, Urethral Stricture, Anterior
Re-Establishing Flow Via Drug Coated Balloon for the Treatment of Urethral Stricture Disease - Registry Study
The ROBUST IV study is designed to collect and better understand "real-world" outcomes for men undergoing urethral dilation using the Optilume Drug Coated Balloon (DCB) for treatment of urethral stricture.
- Conditions
- Urethral Stricture, Urethral Stricture, Anterior, Lower Urinary Tract Symptoms, Anterior Urethral Stricture
- Trial name
- ROBUST IV (NCT03851952)
- Testing
- Optilume Drug Coated Balloon
- Sponsor
- Urotronic Inc.
Urethral Stricture
A Study of Dorsal Versus Ventral Buccal Mucosa Graft Onlay for Bulbar Urethroplasty
The investigators propose a randomized non-blinded comparison of dorsal vs. ventral approach for buccal mucosa graft urethroplasty in the bulbar urethra. Buccal mucosa graft is a common method of repairing the strictured urethra.
- Trial name
- DvV (NCT02634619)
- Testing
- Ventral buccal mucosa onlay urethroplasty, Dorsal buccal mucosa onlay urethroplasty
- Where
- United States
- Volunteers
- 95 people
- Sponsor
- University of California, San Francisco
Elective Penile Surgeries, Hypospadias
Effects of Dexmedetomidine as Adjunct to Pudendal Block for Pediatric Penile Surgery
Caudal block is often performed to relieve postoperative pain in pediatric urological surgery. Recently, pudendal block is also used in penile surgery and it has advantage because of less side effects such as transient weakness…
- Conditions
- Elective Penile Surgeries, Hypospadias, Urethral Fistula or Stricture After Hypospadias Repair, Penile Curvature
- Trial name
- NCT02848157
- Testing
- Dexmedetomidine, plain ropivacaine, Ropivacaine
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Urethral Stricture
Liquid Buccal Mucosa Graft Urethroplasty
Study Objectives The current definitive treatment options for urethral stricture disease include endoscopic urethrotomy known as Direct Vision Internal Urethrotomy (DVIU) or open reconstruction known as urethroplasty (1-6).
- Trial name
- LBMG (NCT03061344)
- Testing
- DVIU treated with liquid buccal mucosal graft
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- State University of New York - Upstate Medical University
Hypospadias Repair
Hemostasis During Hypospadias Surgery
A comparison between the two hemostatic methods of hypospadias repairing operation, in terms of early and mid-term (up to 6 months) failure rate (wound dehiscence and urethral stricture needing reoperation) between the two…
- Trial name
- NCT02268019
- Testing
- tourniquet application, epinephrine injection
- Where
- Iran
- Volunteers
- 70 people
- Sponsor
- Isfahan University of Medical Sciences
Urethral Strictures in Males
Effectiveness and Safety of Autologous Adipose-Derived Regenerative Cells for the Treatment of Urethral Strictures
Autologous adipose-derived regenerative cells (ADRC) extracted using Celution 800/CRS System (Cytori Therapeutics Inc)from a portion of the fat harvested from the patient's front abdominal wall.
- Trial name
- NCT01889888
- Testing
- Submucosal injection of ADRC
- Where
- Russia
- Volunteers
- 12 people
- Sponsor
- Burnasyan Federal Medical Biophysical Center
Urethral Strictures
Efficiency of Cold vs. Laser Internal Urethrotomy Treatment of Urethral Strictures
The purpose of this study is to determine whether laser internal urethrotomy (IU) is as efficient as cold knife internal urethrotomy for treatment of anterior urethral strictures regarding post operative urination outflow…
- Trial name
- IU (NCT01196572)
- Testing
- Internal Urethrotomy
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
Urethral Stricture
Memokath® 044TW Stent for Treatment of Urethral Stricture
The purpose of this study is to evaluate if the placement of a temporary urethral stent for up to 12 months, following dilation or internal urethrotomy (cutting open), results in a higher rate of urethral patency during the first…
- Trial name
- NCT00270504
- Testing
- Memokath stenting
- Where
- 7 sites in United States
- Volunteers
- 92 people
- Sponsor
- Pnn Medical DK
Urethral Stricture
Effect of Mitomycin C on Urethral Stricture Recurrence After Internal Urethrotomy
The aim of this study is to evaluate the efficacy of local injected mitomycin C at the time of internal urethrotomy in order to prevent the recurrence of urethral strictures.
- Trial name
- NCT00918528
- Testing
- Internal urethrotomy, Mitomycin C - local injection
- Where
- Israel
- Sponsor
- Hillel Yaffe Medical Center
Urethral Stricture
Role of Uttarbasti in the Management of Mutra Marga Sankoch (Urethral Stricture)
Uttarbasti is per urethral administration of medicated oil which has been recommended by Sushrut for urinary track disorders. As far as conventional surgery is concerned urethral stricture still remains a challenge due to post…
- Trial name
- NCT00535717
- Testing
- uttarbasti (per urethral administration of medicated oil )
- Volunteers
- healthy volunteers welcome
- Sponsor
- Maharashtra University of Health Sciences