Clinical trials: Ureteral Stone, open to volunteers
Kidney Stone, Ureteric Stone
Safety and Efficacy of Combination of Tamsulosin 0.4 mg Plus Tadalafil 5mg Versus 2.5 mg
Ureteral stenting is a common urological procedure performed to relieve obstruction and facilitate urinary drainage. Despite its effectiveness, stent-related symptoms (SRS) such as dysuria, frequency, urgency, flank pain, and…
- Trial name
- NCT07562282
- Testing
- Tamsulosin
- Where
- Egypt
- Volunteers
- 140 people
- Sponsor
- Ain Shams University
Renal Stones, Retrograde Intrarenal Surgery
Tamsulosin and Intraureteral Aminophylline for Ureteral Access During RIRS
This multicenter randomized controlled trial will evaluate whether preoperative tamsulosin, intraureteral aminophylline, or their combination can improve ureteral access during primary retrograde intrarenal surgery for renal…
- Conditions
- Renal Stones, Retrograde Intrarenal Surgery, Ureteral Access Sheath Placement
- Trial name
- TAM-AMIN-UAS (NCT07623876)
- Testing
- Tamsulosin, Intraureteral Aminophylline
- Where
- 3 sites in Egypt
- Volunteers
- 322 people
- Sponsor
- Beni-Suef University
Ureteral Stone
Patient Positioning for Treatment of Proximal Ureteral Stones
Ureteroscopic management of proximal ureteral stones presents technical challenges including stone retropulsion, prolonged operative time, and conversion to intrarenal treatment.
- Trial name
- NCT07601932
- Testing
- Reverse Trendelenburg Position, T-Tilt Position
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Kidney Stone, Retrograde Intrarenal Surgery
Ureteral Stenting After Retrograde Intrarenal Surgery for Renal Stones
Several studies evaluated the benefit of a short-term external ureteral catheter (UC) compared to double-J (DJ) ureteral stent after flexible ureteroscopy (URS); the results were controversial.
- Conditions
- Kidney Stone, Retrograde Intrarenal Surgery, Ureteral Stent
- Trial name
- NCT05738304
- Testing
- Retrograde intrarenal surgery with external ureteral catheter, Retrograde intrarenal surgery with double J internal ureteral stent
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Al-Azhar University
Pediatric Urolithiasis, Kidney Stone
Standard Versus Flexible and Navigable Suction Ureteral Access Sheath in Pediatric Flexible Ureterorenoscopy for Renal Stones < 2 cm
This randomized controlled trial aims to compare the efficacy and safety of a Flexible and Navigable Suction Ureteral Access Sheath (FANS) versus a standard ureteral access sheath during flexible ureterorenoscopy (FURS) in…
- Conditions
- Pediatric Urolithiasis, Kidney Stone, Nephrolithiasis
- Trial name
- FANS-UAS (NCT07689565)
- Testing
- Standard Ureteral Access Sheath (Boston Scientific)., Flexible and Navigable Suction UAS (ClearPetra).
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Tanta University
Ureteral Stent Placement, Kidney Stone
NSAIDs Stent Study
This is a pilot study to (1) evaluate the effect of Ketorolac on inflammatory response and its impact on stent related symptoms in patients undergoing stent placement procedure and (2) assess feasibility of recruitment…
- Trial name
- NCT03638999
- Testing
- Ketorolac Trometamol 30Mg/1mL Injection, Normal saline
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- Washington University School of Medicine
Acute Obstructive Nephropathy
Primary Ureteroscopy for Acute Obstructive Nephropathy Due to Ureteral Stones: A Prospective Non-randomized Feasibility and Safety Trial
Ureteroscopy (URS) is a widely used minimally invasive procedure for the management of ureteral and renal stones (1). While the procedure is generally safe and effective, patient factors such as renal function, operative time…
- Trial name
- NCT07177313
- Testing
- Ureteroscopy
- Volunteers
- 60 people
- Sponsor
- Assiut University
Ureteral Calculi
Comparison of Mirabegron and Tamsulosin for Ureteral Stone Expulsion
This randomized controlled trial compares the efficacy and safety of four treatment strategies for ureteral stone expulsion: Mirabegron alone, Tamsulosin alone, a combination of both, and standard conservative care.
- Trial name
- NCT07310797
- Testing
- Mirabegron, Tamsulosin
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation
Kidney Calculi, Ureteral Calculi
New Laser and Suction Sheath for Kidney Stone Treatment
The goal of this clinical trial is to learn if the combination of super pulsed thulium fiber laser (sTFL) with a flexible negative pressure suction sheath is more effective and safer than sTFL with a conventional sheath in…
- Trial name
- NCT06667466
- Testing
- Super Pulsed Thulium Fiber Laser (sTFL) + Flexible Negative Pressure Ureteral Access Sheath (UAS) Intervention, Super Pulsed Thulium Fiber Laser (sTFL) + Conventional Ureteral Access Sheath (UAS) Intervention
- Volunteers
- 140 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Renal Stone Disease, Ureteral Stricture
Long-term Safety of UAS-assisted vs Sheathless RIRS in Non-prestented Patients
This retrospective comparative cohort study will include adult patients who underwent primary RIRS for renal stones ≤20 mm at Al-Azhar University Hospitals between January 2020 and December 2025.
- Conditions
- Renal Stone Disease, Ureteral Stricture, Hydronephrosis, Urolithiasis
- Trial name
- NCT07767773
- Testing
- Ureteral access sheath-assisted RIRS, Sheathless RIRS
- Where
- Egypt
- Volunteers
- 1,200 people
- Sponsor
- Al-Azhar University
Urinary Stone
Differences in Postoperative Symptoms With Four Ureteral Stents
This is a prospective randomized controlled trial designed to assess the differences in postoperative symptoms related to placement of a 6Fr Percuflex ureteral stents, 6Fr Tria ureteral stents, 4.8Fr Percuflex ureteral stents…
- Trial name
- NCT06083051
- Testing
- 6Fr Percuflex ureteral stents, 6Fr Tria ureteral stents, 4.8Fr Tria ureteral stents
- Where
- United States
- Volunteers
- 272 people
- Sponsor
- University of Wisconsin, Madison
Urinary Calculi, Ureterocele
Shuotongo Ureteroscopy for Upper Urinary Tract Stones
The purpose of this study is to use the Shuotong ureteroscopy for surgical treatment of patients with upper urinary tract stones, taking advantage of the fact that the Shuotong mirror can be used for simultaneous lithotripsy and…
- Trial name
- SFUUTS (NCT05712785)
- Testing
- Use of shuotong ureteroscopy
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Handan First Hospital
Ureteral Stone
UPURS Trial for Patient-centered Management of Symptomatic Obstructing Stones
A prospective, non-blinded, randomized controlled trial studying the management of symptomatic ureteral stones. This study will compare upfront ureteroscopy vs observation and delayed intervention for patients presenting to the…
- Trial name
- UPURS (NCT05715086)
- Testing
- Ureteroscopy
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Urolithiasis, Kidney Calculi
Human Voice vs AI-Cloned Voice Audio Added to Written Consent Before Ureteroscopy or Retrograde Intrarenal Surgery (AUDIO-CONSENT)
Before kidney stone surgery with a flexible or semirigid ureteroscope, patients must read and sign a written consent form, but many patients find these forms long and hard to understand.
- Conditions
- Urolithiasis, Kidney Calculi, Ureteral Calculi, Informed Consent
- Trial name
- AUDIO-CONSENT (NCT07859436)
- Testing
- Standard written informed consent, Human-voice audio consent recording, AI-cloned-voice audio consent recording
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 240 people
- Sponsor
- Aydin Adnan Menderes University
Kidney Calculi; Ureteral Calculi
Evaluation of Enhanced Lithotripsy System (ELS) in the Treatment of Urinary Stones, A Pivotal Trial
The purpose of this study is to evaluate the safety and performance of the ELS to treat urinary stones. The ELS is intended to break urinary stones into small fragments that can pass during or after the procedure with less or no…
- Trial name
- ELS (NCT06942949)
- Testing
- ELS (Enhanced Lithotripsy System)
- Where
- 20 sites in United States
- Volunteers
- 101 people
- Sponsor
- Avvio Medical
Kidney Stones
Comparison of Smart Pressure-Controlled Flexible Ureteroscopy and Flexible Suction Ureteral Access Sheath-Assisted Flexible Ureteroscopy for 2-3 cm Renal Stones
This prospective, multicenter, randomized, non-inferiority controlled trial aims to compare the efficacy and safety of smart pressure-controlled flexible ureteroscopy and flexible ureteroscopy assisted by a distal flexible…
- Trial name
- NCT07909577
- Testing
- Smart Pressure-Controlled Flexible Ureteroscopy, Distal Flexible Suction Ureteral Access Sheath-Assisted Flexible Ureteroscopy
- Volunteers
- 750 people
- Sponsor
- The First Affiliated Hospital of Guangzhou Medical University
Upper Urinary Tract Calculi
A Comparative Study of Three Ureteral Stenting Strategies After Ureteroscopic Lithotripsy for Upper Urinary Tract Calculi
In recent years, with the widespread popularization of the enhanced recovery after surgery (ERAS) concept, tubeless ureteroscopic lithotripsy (URL) has gradually become a research hotspot.
- Trial name
- NCT07616505
- Testing
- Upper urinary tract calculi
- Volunteers
- 90 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Renal Stones
Ureteroscopic Lithotripsy for Renal Stones Using a Sheathless Approach or Using a Flexible and Navigable Ureteral Access Sheath (FANS)
The primary aim of the study is to compare stone free rates following ureteroscopic (URS) lithotripsy for renal stones with Thulium Fiber Laser (TFL) using a sheathless approach (low power laser settings) or using a flexible and…
- Trial name
- NCT07741084
- Testing
- Sheathless URS, FANS, low power, FANS, high power
- Where
- Norway
- Volunteers
- 225 people
- Sponsor
- Haukeland University Hospital
Kidney Stones, Nephrolithiasis
Effect of Complete Suction-Induced Collapse of the Renal Collecting System at the End of RIRS on Early Postoperative Outcomes
The purpose of this study is to evaluate whether actively suctioning the renal collecting system to induce a "collapse" state at the end of retrograde intrarenal surgery (RIRS) can reduce postoperative pain and infection in…
- Conditions
- Kidney Stones, Nephrolithiasis, Renal Calculi
- Trial name
- NCT07535281
- Testing
- Complete suction-induced collapse, Standard RIRS with natural drainage
- Where
- South Korea
- Volunteers
- 90 people
- Sponsor
- Kangdong Sacred Heart Hospital
Distal Ureteral Stone, Urolithiasis
L-Citrulline Versus Tamsulosin for Medical Expulsive Therapy of Distal Ureteral Stones
This study will compare L-citrulline and tamsulosin as medical expulsive therapy for adults with single distal ureteral stones. Eligible participants with a single distal ureteral stone measuring 5 to 10 mm will be randomly…
- Conditions
- Distal Ureteral Stone, Urolithiasis, Ureteral Calculi
- Trial name
- NCT07617909
- Testing
- L-Citrulline, Tamsulosin
- Where
- Egypt
- Volunteers
- 120 people
- Sponsor
- Beni-Suef University