Clinical trials: Upper Respiratory Infection
Cough, Upper Respiratory Tract Infections
Effect of Over-the-counter NSAIDS on Cough Reflex Sensitivity in Patients with Upper Respiratory Tract Infections
The goal of this mechanism of disease study is to investigate the effect of flurbiprofen, a non-steroidal anti-inflammatory drug (NSAID), on the cough hypersensitivity associated with upper respiratory tract infections (URTI).
- Trial name
- NCT05955885
- Testing
- Flurbiprofen Oral Lozenge, Difflam, Flurbiprofen 8.75 MG
- Where
- Australia
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Hay Fever, Asthma
Evaluating the Potential of Large Language Models for Respiratory Disease Consultations
The clinical trial aimes to evaluate multiple large language models in respiratory disease consultations by comparing their performance to that of human doctors across three major medical consultation scenarios.
- Conditions
- Hay Fever, Asthma, Acute Upper Respiratory Infection, Pulmonary Embolism
- Trial name
- EPLLMMRDC (NCT06457269)
- Testing
- Diagnosis by three human doctors, Diagnosis by ChatGPT-3.5 (with search capabilities), Diagnosis by ChatGPT-3.5 (without search capabilities)
- Where
- China
- Volunteers
- 703 people
- Sponsor
- North Sichuan Medical College
Immune Response, Upper Respiratory Tract Infection
Walnut and Immunity Study
The main objective of the study is to determine if eating walnuts enhances immune function, in older free-living men and postmenopausal women with overweight.
- Trial name
- walnutimmune (NCT05915390)
- Testing
- walnuts, Habitual diet
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Loma Linda University
Acute Upper Respiratory Tract Infection, Bacterial Infections
A Cluster Randomized Controlled Trial to Compare the Rate of Antibiotic Infusion
Acute upper respiratory tract infection, commonly known as upper respiratory infection, is an acute inflammation primarily affecting the nose, pharynx, or larynx caused by various viruses and/or bacteria.
- Trial name
- NCT06620341
- Testing
- drug education
- Where
- China
- Volunteers
- 11,900 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Upper Respiratory Tract Infection (URTI)
Poplar-type Propolis Dry Extract ESIT12 : Immunomodulation Efficacy Study
The aim of the present investigation is to evaluate the immunomodulation effect of ESIT12, a poplar-type propolis dry extract standardized in polyphenols, and its efficacy in subjects at risk of contracting upper respiratory…
- Trial name
- NCT05598749
- Testing
- Verum
- Where
- Spain
- Volunteers
- 309 people, healthy volunteers welcome
- Sponsor
- Fytexia
Viral Infection, Acute Respiratory Infection
Urgent Care Management of Respiratory Illness Enabled With Novel Testing Pathway
Rapid diagnosis and precise treatment have become possible with multiplex polymerase chain reaction (PCR) panels that can identify a variety of causative agents of acute respiratory illnesses such as bacterial and viral…
- Conditions
- Viral Infection, Acute Respiratory Infection, Upper Resp Tract Infection
- Trial name
- URGENT (NCT05467007)
- Testing
- BioFire® Respiratory Panel 2.1-EZ
- Where
- 2 sites in United States
- Volunteers
- 360 people
- Sponsor
- Andrew Meltzer
Upper Respiratory Tract Infections, Gastrointestinal Infection
Preventive Effect of Cow's Milk Fermented With Lactobacillus Paracasei CBA L74 on Common Infectious Diseases in Children
this is a double-blind randomized placebo controlled clinical trial. 200 healthy children aged 12-48 months, attending day care or preschool for at least 5 days a week, regularly checked by the family pediatrician (FP) involved…
- Conditions
- Upper Respiratory Tract Infections, Gastrointestinal Infection, Children, Only
- Trial name
- FERCT19 (NCT05484102)
- Testing
- milk fermented with lactobacillus paracasei CBA L74
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Bari
Upper Respiratory Tract Infections, Perioperative Respiratory Complications
Interest of Lidocaine in Children with Upper Airway Infection Undergoing General Anesthesia
The goal of this clinical trial is to determine whether intravenous (IV) lidocaine reduces the incidence of perioperative respiratory complications (PRCs) in children with upper respiratory tract infections undergoing general…
- Trial name
- NCT06584461
- Testing
- Lidocaine (drug)
- Where
- Tunisia
- Volunteers
- 102 people
- Sponsor
- Tunis University
Upper Respiratory Tract Infections
LiveSpo Navax® Supports the Treatment of Acute Rhinosinusitis and Otitis Media
Acute respiratory tract infections (ARTIs), such as acute rhinosinusitis (ARS) and acute otitis media (AOM), are common worldwide and caused by viruses or bacteria entering the body through the mouth and nose.
- Trial name
- NCT05804123
- Testing
- 0.9% NaCl physiological saline Nasal-spraying, LiveSpo Navax®, Augmentin 500Mg Tablet
- Where
- Vietnam
- Volunteers
- 175 people
- Sponsor
- Anabio R&D
Acute Upper Respiratory Tract Infection, Traditional Chinese Medicine
Clinical Study on the Efficacy and Safety of Qingre Heji in the Treatment of Acute Upper Respiratory Tract Infection
Originating from China, TCM complements conventional approaches by alleviating symptoms, balancing physical conditions, and enhancing immunity. Clinical studies have shown TCM to be safe and effective in treating AURI.
- Conditions
- Acute Upper Respiratory Tract Infection, Traditional Chinese Medicine, Randomised Controlled Trial
- Trial name
- NCT06520618
- Testing
- Qing Re He Ji, Shuanghuanglian Oral Liquid
- Where
- China
- Volunteers
- 268 people
- Sponsor
- Shengjing Hospital
Upper Respiratory Tract Infections
A Study for Assessing the Efficacy and Safety ParActin® in Individuals With Upper Respiratory Tract Infections
The present study is a randomized, double-blind, placebo-controlled, comparative study. 176 individuals will be screened, and considering a screening failure rate of 15 percent approximately 150 will be randomized in a ratio of…
- Trial name
- NCT06355661
- Testing
- ParActin®: 300 mg + MCC: 100 mg (± 10%) per Capsule, MCC: 400 mg (± 10%) per Capsule
- Where
- 9 sites in India
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Upper Respiratory Tract Infections, Virus
Edinburgh and Lothian Virus Intervention Study in Kids
ELVIS Kids is a parallel, open label, randomised controlled trial (RCT) of Hypertonic Saline (HS) nose drops (~2.6% NaCl) vs. standard care in children <7 years of age with symptoms of an Upper Respiratory Tract Infection (URTI).
- Conditions
- Upper Respiratory Tract Infections, Virus, Virus Shedding, Pediatric ALL
- Trial name
- ELVIS Kids (NCT03463694)
- Testing
- Na Cl solution
- Where
- United Kingdom
- Volunteers
- 407 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Upper Respiratory Tract Infections
Phenotype of Headache and Facial Pain in Upper Respiratory Tract Infections
The goal of this longitudinal study is to assess headache and facial pain features in patients with upper respiratory tract infections (URTI). The main question it aims to answer are: 1.
- Trial name
- NCT06127186
- Testing
- Swab test for viral antigens
- Where
- Poland
- Volunteers
- 223 people
- Sponsor
- Marcin Straburzynski
Immunomodulation, Respiratory Tract; Infection, Upper (Acute)
Effect of an Immune-boosting Food Supplement on the Severity and Frequency of Pediatric Respiratory Tract Infections
The goal of this clinical trial is to evaluate the efficacy of the product in developing immune reinforcement that results in decreased susceptibility to respiratory infections of viral origin in children aged 3 to 10 years with…
- Trial name
- NCT06218225
- Testing
- Verum
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera Universitaria Policlinico "G. Martino"
Upper Respiratory Tract Infection
A Study to Evaluate the Efficacy of EQ-778 on Upper Respiratory Tract Health Status in Healthy Adults
This study is a randomized, double-blind, Placebo Controlled study to evaluate the efficacy of 180 days administration of EQ-778 on upper respiratory tract health status in healthy adults
- Trial name
- NCT05835375
- Testing
- EQ-778
- Where
- 13 sites in India
- Volunteers
- 374 people, healthy volunteers welcome
- Sponsor
- Vedic Lifesciences Pvt. Ltd.
Upper Respiratory Tract Infections, Acute Respiratory Tract Infection
Implementation of Academic Detailing Interventions on Prescribing of Antimicrobial Drugs in Primary Health Care
World increase in mortality from consequences of antimicrobial resistance (AMR) represents a significant public health problem. Irrational prescribing of antimicrobial drugs (AMD) in general population is one of the main causes…
- Conditions
- Upper Respiratory Tract Infections, Acute Respiratory Tract Infection, Viral Infection
- Trial name
- NCT05090475
- Testing
- Academic detailing intervention
- Where
- Croatia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- General Hospital Koprivnica
Infection of Upper Respiratory Tract Caused by 2019-nCoV
SA55 Injection Phase II Study in the Treatment of Mild/Moderate COVID-19 Patients
Evaluating the efficacy and safety of SA55 injection in light/medium COVID-19 patients
- Trial name
- NCT06042764
- Testing
- SA55 Injection
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Sinovac Life Sciences Co., Ltd.
Respiratory Tract; Infection, Upper (Acute), Colonization, Asymptomatic
Studying Respiratory Infections and Colonisation in Children Using Daily Minimally-invasive Nasal Sampling
Rationale: Respiratory tract infections (RTI) are a major cause of morbidity in young children in high- income countries and the major cause of mortality in developing countries.
- Trial name
- SAMSAM (NCT06049537)
- Where
- Netherlands
- Volunteers
- 46 people
- Sponsor
- Leiden University Medical Center
Upper Respiratory Tract Infection, Lower Respiratory Infection
Bioequivalence Study of Azithromycin Capsule and Reference Formulation Sumamed * in Healthy Adult Subjects in China
Main research purpose To investigate the pharmacokinetics of the test preparation azithromycin capsule and the reference preparation azithromycin capsule (Sumamed®) in Chinese healthy adult subjects by single oral administration…
- Conditions
- Upper Respiratory Tract Infection, Lower Respiratory Infection, Skin Infection, Subcutaneous Tissues Infection
- Trial name
- NCT06149117
- Testing
- test product (T) azithromycin capsule and reference product (R) azithromycin capsule "Sumamed®"
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Peking University People's Hospital
Upper Respiratory Tract Infection
Effect of eHealth on AB Use of Children With Acute, Uncomplicated URTIs
The goal of this clinical trial is to test the effectiveness of two self-care eHealth applications in parents of children with uncomplicated upper respiratory tract infections (URTIs).
- Trial name
- NCT06140446
- Testing
- FeverApp, DMT App
- Where
- Netherlands
- Volunteers
- 411 people
- Sponsor
- Max Nieuwdorp