Clinical trials: Upper Gastrointestinal Endoscopy
Anesthesia, Anxiety
Media Use, Anxiety, Sedation, and Recovery in Children Having Upper GI Endoscopy
This observational study will investigate whether problematic digital media use is associated with anxiety in children undergoing a planned upper gastrointestinal endoscopy, a camera examination of the upper digestive tract.
- Trial name
- PMU-ASR-ENDO (NCT07916168)
- Testing
- Problematic Media Use
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Healthy Individual
CDSS-assisted UGI Endoscopy vs. Routine Screening Endoscopy
This study aimed to find the CDSS-assisted upper GI endoscopy has clinical benefit compared to conventional routine screening upper GI endoscopy. Investigators will conduct a pilot randomized controlled study.
- Trial name
- NCT05452473
- Testing
- CDSS-assisted upper GI endoscopy, no intervention
- Where
- South Korea
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Chuncheon Sacred Heart Hospital
Obstructive Sleep Apnea
Evaluation of Post-surgical Improvement in OSA Patients After Imaging of Upper Airway Using CBCT and DISE vs DISE Only
CBCT is considered an innovative imaging modality that can view the upper respiratory airway anatomy in a 3D manner. Recent studies tried to evaluate the accuracy of CBCT in analyzing the upper respiratory airway and its related…
- Trial name
- NCT04727346
- Testing
- CBCT, DISE
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Cairo University
Endoscopy, Education
Simulation-assisted Teaching in Learning Gastroscopy
This project is a single-blinded randomized controlled trial investigating the effect of simulation-based teaching in learning gastroscopy for medical doctors.
- Conditions
- Endoscopy, Education, Gastroscopy, Esophagogastroduodenoscopy
- Trial name
- NCT04247399
- Testing
- Simulation-based learning
- Where
- Denmark
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Anders Bo Nielsen
Undergoing Esophagogastroduodenoscopy (EGD)
High Resolution Optical Imaging of the Esophagus Using the Nvision Volumetric Laser Endomicroscopy (VLE™) Imaging System
This is a single center, single arm, open label observational trial of patients undergoing EGD. The primary objective of this clinical trial is to evaluate the ability of physicians to position the NvisionVLE catheter to acquire…
- Trial name
- NCT01844921
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NinePoint Medical
Barrett Esophagus
Does Laparoscopic Sleeve Gastrectomy Lead to Barrett's Esophagus, 5-year Esophagogastroduodenoscopy Findings: A Retrospective Cohort Study
Introduction Laparoscopic Sleeve Gastrectomy (LSG) is one of the most prevalent approaches to tackle obesity and its co-morbidities.
- Trial name
- NCT04587310
- Testing
- Laparoscopic Sleeve Gastrectomy
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Eliana Al Haddad
Anesthesia
Intermittent Boluses Versus Infusion of Propofol During Gastroscopy
It is unclear whether continuous infusion or intermittent bolus injection of propofol is better for achieving adequate sedation during a standard upper endoscopy.
- Trial name
- NCT06378879
- Testing
- Propofol 100 MG in 10 ML Injection
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al-Balqa Applied University
Capnography as an Adjunct to Standard Monitoring During Midazolam and Propofol Sedation for Interventional Upper GI Endoscopy
Capnography During Upper GI Endoscopy
In this randomized controlled trial the utility of capnography and IPI gets evaluated. Hypoxemia may occur during sedation with midazolam and propofol.
- Trial name
- NCT01242345
- Testing
- Capnography
- Where
- 3 sites in Germany
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Anesthesia Morbidity
HIFLO ENDO-High Flow Nasal Cannula in GI Endoscopy
Millions of patients undergo upper GI endoscopy in the United States each year. A large number of these patients have anesthesia to assist with their comfort during the procedure.
- Trial name
- NCT03028688
- Testing
- High flow nasal cannula oxygen
- Where
- United States
- Volunteers
- 262 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Anesthesia
Intranasal Dexmedetomidine Versus Intranasal Midazolam as a Premedication in Pediatrics Undergoing Upper GI Endoscopy
compare the effectiveness of intranasal dexmedetomidine and midazolam as a premedication in sedation of preschool children in GI endoscopy
- Trial name
- NCT06181682
- Testing
- Dexmedetomidine, Midazolam
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Obesity, Bariatrics
Ketamine and Propofol Combination Versus Propofol for Upper Gastrointestinal Endoscopy
Propofol is one of the most popular anesthetic drugs used for sedation during upper gastrointestinal endoscopies due to its quick onset and quick resolution of symptoms allowing patients to leave the hospital sooner.
- Conditions
- Obesity, Bariatrics, Sleep Apnea Syndromes, Gastric Bypass
- Trial name
- NCT02643979
- Testing
- Ketofol, Propofol, Saline
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Capsule Endoscopy
Detachable String MCE for Upper Gastrointestinal Tract and Small Bowel
This study aims to evaluate the feasibility and safety of DS-MCE with a novel way for complete examination in UGI tract and small bowel, compared with EGD.
- Trial name
- NCT04329468
- Testing
- DS-MCE
- Where
- China
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Zhuan Liao
Type 2 Diabetes
Intraluminal Imaging of Duodenal Layer Morphometry in Patients With and Without Type 2 Diabetes
This observational study is conducted to determine how the duodenal layer thicknesses (mucosa, submucosa, and muscularis) vary with several factors in patients with and without type 2 diabetes.
- Trial name
- NCT02688920
- Testing
- EUS and OCT imaging
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Victoria Gomez
Endoscopic Diagnosis in Esophagus
The Diagnostic Yield of Cap Assisted Upper Endoscopy in Esophagus
Cap assisted colonoscopy, a simple technique of fixing a transparent plastic cap to the tip of the colonoscope, was proven to increase the adenoma detection rate during screening colonoscopy by helping to depress and flatten…
- Trial name
- Kappa-III (NCT02883621)
- Testing
- cap assisted upper endoscopy, standard upper endoscopy
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Technical University of Munich
Sedative During Endoscopy
Implementing Virtual Reality (VR) to Reduce Sedation
The study is a prospective pilot patients aged 21 to 65 undergoing screening colonoscopy or diagnostic upper endoscopy. Patients are administered minimal sedation (2 mg of Versed and 25 mg of Fentanyl) and are given Virtual…
- Trial name
- NCT06349564
- Testing
- Pico 4 Enterprise headset with noise cancelling headphones
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Symptoms and Signs, Malignancy
Correlation of Endoscopic Findings and Symptoms in Patients Undergoing the First Upper Gastrointestinal Endoscopy
Endoscopy is the best means of finding early stage of upper gastrointestinal diseases, especially early cancer and benign ulcers.
- Conditions
- Symptoms and Signs, Malignancy, Ulcer Peptic
- Trial name
- NCT03736824
- Testing
- endoscopy
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Gastric Residual Volume, Upper Endoscopy
The Effect of Carbohydrate Loading 2 Hours Before Gastroscopy on Gastric Residual Volume and Patient's Well-being Score
This is a single-blind randomized controlled trial with a stratified (diabetes mellitus, non-diabetes mellitus), balanced randomization (1:1), placebo-controlled study regarding the effect of carbohydrate loading 2 hours prior to…
- Trial name
- Carborie (NCT05106933)
- Testing
- Plain water, Carborie
- Where
- Malaysia
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Hospital Universiti Sains Malaysia
Advanced Colorectal Neoplasms, Throat Cancer
Fecal Screening Assay for Taiwanese Population
Fecal occult blood test (FOBT) is a convenient tool for the screening of asymptomatic gastrointestinal (GI) bleeding while 「guaiac-based fecal occult test (G-FOBT) 」 is increasingly replaced by the use of an 「immunochemical-based…
- Conditions
- Advanced Colorectal Neoplasms, Throat Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT01341197
- Testing
- Fecal immunochemical test, guaiac fecal occult-blood test, and Helicobacter pylori stool antigen test
- Where
- Taiwan
- Volunteers
- 3,172 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
EGD Procedure
Moderate Sedation for Elective Upper Endoscopy With Balanced Propofol Versus Propofol Alone: a Randomized Clinical Trial
Since introduction in 1989, propofol has gained wide acceptance for sedation during endoscopic procedures. The optimal sedation drug during esophagogastroendoscopy (EGD) is not established.
- Trial name
- NCT02174588
- Testing
- Midazolam + propofol, propofol
- Where
- South Korea
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Capsule Endoscopy
The Second-Generation MCCG for Upper Gastrointestinal Tract.
The aim of this study is to evaluate the clinical application of the second-generation MCCG with higher image resolution and frame rate for upper gastrointestinal tract compared with the first-generation.
- Trial name
- NCT03977935
- Testing
- the second-generation MCCG
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital