Clinical trials: Upper Extremity Paralysis
Acute Stroke
Robot Assisted Upper Limb Neuro-Rehabilitation
Our long term objectives are to understand the mechanisms of motor impairment following neurologic injury and to develop interventions to improve motor recovery.
- Trial name
- NCT00011583
- Testing
- Robot-assisted therapy, Traditional therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- US Department of Veterans Affairs
Hemiplegic Cerebral Palsy
Effects of Plyometric Training Versus Virtual Reality Among Hemiplegic Cerebral Palsy
The purpose of this study is to compare the effects of plyometric training versus virtual reality on upper limb among hemiplegic cerebral palsy
- Trial name
- NCT05931640
- Testing
- Virtual Reality, Plyometric Training
- Where
- Pakistan
- Volunteers
- 28 people
- Sponsor
- Riphah International University
Nerve Injury, Peripheral Nerve Injuries
Promoting Healing of Injured Nerves With Electrical Stimulation Therapy
This study is evaluating a new therapeutic use of electrical stimulation to promote nerve healing and improve functional recovery following surgical intervention for peripheral nerve injury in arm.
- Conditions
- Nerve Injury, Peripheral Nerve Injuries, Peripheral Nerve Injury Upper Limb, Nerve Palsy
- Trial name
- PHINEST (NCT05884125)
- Testing
- Checkpoint BEST System
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Checkpoint Surgical Inc.
Upper Extremity Paresis, Hemiplegia and/or Hemiparesis Following Stroke
Task or Virtual Reality Intervention for Improving UE Function
People with one arm that does not function well due to a stroke, head injury, or cerebral palsy, and a fully functional other arm, will be randomly assigned to receive one of the two interventions first, followed by the other…
- Conditions
- Upper Extremity Paresis, Hemiplegia and/or Hemiparesis Following Stroke, Hemiplegic Cerebral Palsy
- Trial name
- NCT03811275
- Testing
- Virtual Reality (A) then Task (B), Task (B) then Virtual Reality (A)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Idaho State University
Unilateral Cerebral Palsy
HEMImprove 1.0 in Children and Adolescents With Unilateral Cerebral Palsy
This study aims to evaluate the effectiveness and usability of HEMImprove 1.0, a gamified mobile application designed to improve upper limb motor function in adolescents with unilateral cerebral palsy.
- Trial name
- HEMImprove-APP (NCT07041944)
- Testing
- HEMImprove APP, exercises to upper limb
- Volunteers
- 36 people
- Sponsor
- University of Castilla-La Mancha
Cerebral Palsy
Upper Extremity Selective Voluntary Motor Control in Children With Unilateral Cerebral Palsy
The aim of the study was to determine upper extremity selective motor control (SMC) in Children with Unilateral Cerebral Palsy (CP).
- Trial name
- NCT03504787
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Gazi University
Cerebral Palsy (CP), Diplegic Cerebral Palsy
Effect of Intensive Segmental Trunk Training on Upper Extremity Function and Seated Postural Stability in Children With Spastic Diplegic Cerebral Palsy
The goal of this randomized controlled trial is to evaluate whether intensive segmental trunk training (ISTT) can improve upper extremity function and seated postural stability in children aged 4-12 years with spastic diplegic…
- Conditions
- Cerebral Palsy (CP), Diplegic Cerebral Palsy, Trunk Mobility, Upper Extremity Function
- Trial name
- NCT07692087
- Testing
- Intensive Segmental Trunk Training, Standard Physical Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- University of Lahore
Cerebral Palsy
Strength and Dexterity of Less Affected Hand of Hemiparetic Cerebral Palsy Children
The contralateral hand deficits are often masked by the complex clinical presentation of the more affected hand in children with spastic hemiparesis.
- Trial name
- NCT05546164
- Testing
- Assessment of hand grip strength, Assessment of pinch strength, Assessment of upper limb dexterity
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Unilateral Spastic Cerebral Palsy
Muscle Elastography in Spastic Cerebral Palsy
To date, clinical tests are unable to differentiate between the cause of muscle stiffness, although a manual instrumented spasticity assessment for the lower limb that utilizes surface electromyogram has recently been proposed.
- Trial name
- NCT03112434
- Testing
- Botulinum toxin type A
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Hospital for Special Surgery, New York
Unilateral Cerebral Palsy
Sensitivity of an Upper Limb Motion Analysis Protocol to Changes in Kinematics and Muscle Activity After Constraint Induced Therapy in Children With Hemiplegia
In France, Cerebral Palsy (CP) affects 1 in 450 births. It results from lesions of the brain, before, during, or shortly after birth. These non-progressive lesions cause muscle impairments, responsible for activity limitations.
- Trial name
- MouvsupTCIHemi (NCT03099993)
- Testing
- Measurement of maximal forces of elbow pronosupination and flexion-extension
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Hemiplegia, Cerebral Palsy Spastic Hemiplegic
Arm More + Camp: An Implementation Study
Our primary aim is to evaluate the implementation cost of a full day modified constraint induced movement therapy camp for children with hemiparesis.
- Conditions
- Hemiplegia, Cerebral Palsy Spastic Hemiplegic, Acquired Brain Injury (Including Stroke)
- Trial name
- NCT07065916
- Testing
- Modified Constraint Induced Movement Therapy
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Calgary
Hemiplegia, Upper Extremity Problem
Unaffected Hand in Hemiplegia
The primary aim of our study is to evaluate the functional status of the unaffected hand in hemiplegic patients. The secondary aims are to compare the functional states of the unaffected hand between right and left hemiplegias…
- Trial name
- NCT05194501
- Testing
- Nine Hole Peg Test, Jamar dynamometer, pinchmeter
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Cerebral Palsy Infantile
Effect of Transcranial Direct Current Stimulation on Upper Extremity of Children With Hemiparesis
Purpose: The aim of the study is to determine the combined effect of transcranial direct current stimulation (tDCS) and activities in virtual reality on the functional recovery of the upper extremity function of the children with…
- Trial name
- NCT04257981
- Testing
- Brain stimulator v3.0
- Where
- 2 sites in Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- Majmaah University
Cerebral Palsy Infantile, Chronic Pain
Trunk and Upper Extremities Program Effect in Decreasing Compensation Patterns in Unilateral Cerebral Palsy Children
The goal of this clinical trial is to test the effectiveness of a trunk and upper extremities exercise program. The main questions it aims to answer are: Whether the program decreases compensation patterns in unilateral cerebral…
- Conditions
- Cerebral Palsy Infantile, Chronic Pain, Upper Extremity Dysfunction
- Trial name
- TUPEX (NCT06069765)
- Testing
- TUPEX
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fundacio Aspace Catalunya
Tetraplegia
Electrical Stimulation in Denervated Muscles of the Upper Limbs
In the last decade the stimulation of denervated muscles got more attention. Not at least because of the promising results of the RISE project (Use of electrical stimulation to restore standing in paraplegics with long-term…
- Trial name
- NCT03698136
- Testing
- Stimulation of denervated muscles
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Swiss Paraplegic Research, Nottwil
Cerebral Palsy Spastic Diplegia
Effect of Botulinum Toxin on Selective Motor Control and Pain in Diplegic Cerebral Palsy
The aim of this study is to investigate the effects of Botulinum Neurotoxin-A (BoNT-A) injection applied to spastic muscles on pain sensation and Selective Motor Control (SMC) in cases diagnosed with diplegic spastic Cerebral…
- Trial name
- NCT06583343
- Testing
- OnabotulinumtoxinA, Conventional Physical Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Cerebral Palsy, Hemiplegia
Constraint-induced Movement Therapy (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegic Cerebral Palsy
A randomized control trial of bimanual training. The protocols have been developed at Columbia University to be child friendly and draws upon our experience since 1997 with constraint-induced movement therapy in children with…
- Conditions
- Cerebral Palsy, Hemiplegia, Children, Pediatric
- Trial name
- NCT00305006
- Testing
- Constraint-Induced Movement Therapy (CIMT), Hand-Arm Bimanual Intensive Therapy (HABIT)
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Teachers College, Columbia University
Stroke, Hemiplegia
A Pilot Study Investigating the Feasibility of the Saebo Arm Training Program on an Inpatient Population
Study Objectives: 1. To document the safe and effective application of the F.T.M. Arm Training Program using the SaeboFlex to an inpatient post stroke rehabilitation population. 2.
- Trial name
- NCT00489580
- Testing
- SaeboFlex Dynamic Hand Orthosis, Saebo F.T.M. Arm Training Program
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Kessler Foundation
Cerebral Palsy
Utility of Upper-Extremity Plyometrics in Children With Unilateral Cerebral Palsy
This study was set out to evaluate the effect of a 12-week upper extremity plyometric exercise (Plyo-Ex) on muscle strength and upper extremity function in children with hemiparetic cerebral palsy (Hemi-CP).
- Trial name
- NCT06980246
- Testing
- Plyometric Exercise, Standard exercise program
- Where
- Saudi Arabia
- Volunteers
- 58 people
- Sponsor
- Cairo University
Hemiplegia, Hemiplegic Cerebral Palsy
Actigraphs for Detection of Asymmetries
In hemiplegia quantitatively measurement of the asymmetry in the use of upper limbs could overcome the limitation of many outcome measures in which scores are dependent on the experience and training of the therapist.
- Trial name
- NCT03054441
- Testing
- Actigraph
- Where
- Italy
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- IRCCS Fondazione Stella Maris