Clinical trials: Upper Extremity Injuries
Stress Disorders, Post-Traumatic
Study To Evaluate The Efficacy And Safety Of Balovaptan In Adults With Post-Traumatic Stress Disorder (PTSD)
This study will evaluate the efficacy and safety of 10 mg of oral administration balovaptan once a day (QD) compared with matching placebo in adults with PTSD.
- Trial name
- NCT05401565
- Testing
- Balovaptan
- Where
- 15 sites in United States
- Volunteers
- 29 people
- Sponsor
- Hoffmann-La Roche
Elbow Fracture
The Post-Operative Pain Management of Pediatric Supracondylar Elbow Fractures
The goal of this study is to compare different ways of treating pain after surgery. This research study involves subjects who have a supracondylar elbow fracture and need surgery.
- Trial name
- NCT01328782
- Testing
- Oxycodone with Acetaminophen, Bupivacaine 0.25%, Ropivacaine 0.20%
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- University of Colorado, Denver
Acquired Brain Injury
Effects of Combined Spinal Direct Current Stimulation on Upper Limb Recovery in Acquired Brain Injury
This study will compare different polarities of transcutaneous spinal direct current stimulation combined with robotic-assisted arm training (RAT) in adults with acquired brain injury (ABI).
- Trial name
- NCT03100370
- Testing
- tsDCS-Anodal Stimulation, tsDCS-Cathodal Stimulation, Robotic-assisted training of arm and hand functions
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- The University of Texas Health Science Center, Houston
Rotator Cuff Injury
Suture Anchor Comparison in Rotator Cuff Repairs
Patients will be randomized to receive HEALICOIL™ REGENESORB (the study anchor) or TWINFIX Ultra HA, a similar comparative product, for use in the repair of their shoulder injury.
- Trial name
- NCT02350647
- Testing
- Suture Anchor HEALOCOIL, Suture anchor Twinfix Ultra HA
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- The Hawkins Foundation
Pressure Injury Prevention
Biatain Silicone Sacral for Pressure Injury Prevention in Hospital-admitted Patients at Risk
A post market clinical follow-up study investigating the safety of Biatain Silicone Sacral while used as prevention in hospital admitted patients at risk of developing a pressure injury.
- Trial name
- NCT05619003
- Testing
- Biatain Silicone Sacral dressing
- Where
- 3 sites in Denmark
- Volunteers
- 67 people
- Sponsor
- Coloplast A/S
Postoperative Wound Infection Superficial Incisional, Postoperative Wound Infection Deep Incisional Surgical Site
Safety and Efficacy of D-PLEX in the Prevention of Sternal Infection Post Cardiac Surgery.
This study is aimed to assess the anti-infective efficacy of D-PLEX over a period of 3 months post operation as well as the safety over a period of 6 months, by preventing sternal infection post cardiac surgery in patients above…
- Trial name
- NCT02731573
- Testing
- D-PLEX, Open heart surgery
- Where
- 5 sites in Israel
- Volunteers
- 81 people
- Sponsor
- PolyPid Ltd.
Acute Injury of Upper Extremity
Impact of Keeping a Personal Recovery Diary on Upper Extremity Disability
Primary null hypothesis: Keeping a personal diary has no effect on upper-extremity disability (assessed w/ PROMIS [Patient Reported Outcome Measurement Information System] upper extremity) 8 weeks after injury.
- Trial name
- NCT02361580
- Testing
- Diary
- Volunteers
- 9 people
- Sponsor
- Massachusetts General Hospital
Lower Limb Amputation Above Knee (Injury)
C-Leg 3 and C-Leg 4 Study in Transfemoral Amputees
The aim of this post-market study is to confirm that the microprocessor controlled prosthetic knee components (C-Leg 3 and C-Leg 4) in comparison to mechanical knee joints can bring additional benefit to the users primarily on…
- Trial name
- NCT02765035
- Testing
- C-Leg 4, C-Leg 3
- Where
- 2 sites in Austria, Belgium
- Volunteers
- 18 people
- Sponsor
- Otto Bock Healthcare Products GmbH
Corneal Disease, Corneal Opacity
First in Human (FIH) Study to Assess Safety and Efficacy of the CorNeat KPro for the Treatment of Corneal Blindness
Prospective, open label, single arm, First in Human (FIH) clinical study to assess safety and efficacy of the CorNeat Keratoprosthesis, a synthetic cornea, for the treatment of corneal blindness
- Conditions
- Corneal Disease, Corneal Opacity, Corneal Injuries
- Trial name
- NCT04485858
- Testing
- CorNeat KPro
- Where
- 8 sites in United States, Canada and 3 more
- Volunteers
- 10 people
- Sponsor
- CorNeat Vision Ltd.
Shoulder Injury
Blood Flow Restriction Therapy Following Acute Shoulder Injury Patients
Atrophy and weakness of the shoulder are a common problem following treatment of a number of shoulder and elbow pathologies. Even with relatively short periods of reduced activity, the magnitude of muscle loss can be quite…
- Trial name
- BFR (NCT06223373)
- Testing
- Blood Flow Restriction
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Wake Forest University Health Sciences
Heterotopic Ossification, Humeral Fractures
HO Prophylaxis Therapy for Distal Humerus Fractures
To determine the effectiveness of 500 cGy dose of radiation therapy vs. an untreated group in the prophylactic treatment of heterotopic ossification in distal humerus fractures
- Conditions
- Heterotopic Ossification, Humeral Fractures, Radiation Therapy
- Trial name
- NCT03724422
- Testing
- Radiation
- Where
- 2 sites in United States
- Volunteers
- 3 people
- Sponsor
- University of Louisville
Incisional Hernia
Xen Matrix™ AB Surgical Graft in Ventral or Incisional Midline Hernias
This study aims to prospectively explore the use of XenMatrix™ AB Surgical Graft for ventral or incisional midline hernia repair in patients across all wound classes ("All Comers") through 24 months post repair.
- Trial name
- NCT02691962
- Testing
- Xen Matrix AB
- Where
- 11 sites in United States
- Volunteers
- 75 people
- Sponsor
- C. R. Bard
Radius; Fracture, Lower or Distal End
Cast vs. Splints for Minimally Displaced Distal Radius Fractures in the Elderly
The purpose of this prospective randomized study is to add to the body of knowledge on the treatment of minimally displaced distal radius fractures in patients over 60 years of age.
- Trial name
- NCT02066857
- Testing
- Cast made of generic plaster or fiberglass cast material, Generic "off the shelf" removable splint
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Emory University
Elbow Injury, Elbow Fracture
Pocket Sized Ultrasound (PsUS) and Pediatric Elbow Fractures
The main purpose of this project is to investigate the accuracy of pocket-sized ultrasound (PsUS) in the diagnosis of pediatric elbow fractures.
- Trial name
- NCT05870345
- Testing
- Butterfly IQ
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Edema Arm, Fracture; Wrist
Taping to Control Edema in Patients With Forearm Plaster for Wrist Fracture.
Wrist fractures are a very common event affecting patients of all ages and are estimated to account for approximately 10% -25% of all fractures. 70-90% of fractures are treated with closed reduction and forearm cast.
- Trial name
- NCT04683887
- Testing
- Tape application
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- Azienda Unita Sanitaria Locale di Piacenza
Acute Lung Injury, End Stage Lung Disease
Voxelotor for Improving Oxygen Saturation in Adults
The purpose of the study is to evaluate the efficacy of voxelotor for increasing oxygen saturation in 20 patients with hypoxemia.
- Trial name
- Voxelotor (NCT05289570)
- Testing
- Voxelotor
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Duke University
Grade I/II Ankle Sprain
Evaluate the Efficacy and Safety of Diclofenac Diethylamine 2.32% Gel Applied Twice or Three Times Daily in Patients With Acute Ankle Sprain
The main purpose of this trial is to compare the efficacy and safety of diclofenac diethylamine 2.32% gel applied twice (b.i.d) or three times a day (t.i.d.) with placebo in the treatment of acute ankle sprains (distortions).
- Trial name
- NCT00955513
- Testing
- diclofenac diethylamine gel 2.32%
- Where
- 5 sites in Germany
- Volunteers
- 242 people
- Sponsor
- Novartis
Distal Radius Fracture
Postsurgical Bupivacaine Extended-release Liposome Injection for Open-reduction Internal Distal Radius Fixation.
For patients undergoing open-reduction internal-fixaton (ORIF) of isolated distal radius fractures, administration of 66.5 mg of liposomal bupivacaine to operative field may decrease the need for post-operative narcotic pain…
- Trial name
- NCT02515851
- Testing
- Exparel
- Volunteers
- 30 people
- Sponsor
- University of Louisville
Hand Injuries, Wrist Injuries
Study of A Long Lasting Local Anesthestic for Hand, Wrist or Finger Surgery
The purpose of this study is to compare Exparel, a new, long-lasting numbing medication and a shorter-acting nerve block to a traditional single-shot nerve block in patients having hand, wrist or finger surgery.
- Conditions
- Hand Injuries, Wrist Injuries, Finger Injuries
- Trial name
- NCT02058303
- Testing
- Exparel Forearm block, Bupivacaine supraclavicular block
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Jose Soberon, MD
Elbow Fracture
Radiation Therapy for Heterotopic Ossification Prophylaxis Acutely After Elbow Trauma
The investigators hypothesized that radiation therapy could be safely administered acutely after elbow trauma, and it would decrease the number of patients that would require surgical excision of heterotopic ossification.
- Trial name
- ElbowHO (NCT00991887)
- Testing
- Radiation Therapy (XRT)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences