Clinical trials: Upper Endoscopy
Healthy
Remimazolam Versus Midaszolam for Sedation in Diagnostic Upper Gastrointestinal Endoscopy
The goal of this clinical trial is to compare the efficacy of remimazolam with midazolam in patients undergoing gastrointestinal endoscopy.
- Trial name
- NCT05836545
- Testing
- Remimazolam, Midazolam
- Where
- South Korea
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Gastrointestinal Hemorrhage, Gastrointestinal Neoplasms
Hemostatic Powder Versus Clinical Management for the Treatment of Upper Gastrointestinal Bleeding From Tumor Lesions
This study evaluates the efficacy of the endoscopic hemostatic powder for the treatment of bleeding from malignant lesions of the upper GI tract.
- Trial name
- NCT02820077
- Testing
- Hemospray (Endoscopic treatment with hemostatic powder)
- Volunteers
- 62 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Dysphagia, GERD
Does Use of Topical Lidocaine in EGD Reduce Amount of IV Midazolam and Fentanyl Required and Shorten Recovery Time
Patients will be randomized to a placebo or study group who will receive topical lidocaine prior to EGD. Amount of medication used, recovery time, patient/endoscopist satisfaction will then be assessed.
- Conditions
- Dysphagia, GERD, Abdominal Pain
- Trial name
- NCT02620501
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- Brooke Army Medical Center
Dyspepsia, Gastroesophageal Refluxdisease
Study of Long-Term Use of Proton-Pump-Inhibitors in General Practice
The primary purpose of the study is to determine the effect of esomeprazole compared to placebo in patients from general practice who have previously been treated with proton-pump-inhibitors (PPI) and who have no upper endoscopic…
- Conditions
- Dyspepsia, Gastroesophageal Refluxdisease, Ulcer
- Trial name
- NCT00363701
- Testing
- esomeprazole
- Where
- Denmark
- Volunteers
- 150 people
- Sponsor
- Glostrup University Hospital, Copenhagen
Urothelial Carcinoma
Phase I Study of Percutaneous Valrubicin for Upper Tract Urothelial Carcinoma
The purpose of this study is to learn more about how well the drug valrubicin (VALSTAR®) works to help treat the patient's cancer when administered through a nephrostomy tube inserted through their back into their kidney.
- Trial name
- NCT01606345
- Testing
- Valrubicin
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- H. Lee Moffitt Cancer Center and Research Institute
Dyspepsia, Malabsorption Syndrome
Evaluation of Topical Lidocaine Spray as Adjuvant to Upper Gastrointestinal Endoscopy in Children
There is some controversy in the medical literature regarding the effectiveness of topical lidocaine in children as an adjuvant drug to upper gastrointestinal endoscopy.
- Conditions
- Dyspepsia, Malabsorption Syndrome, Gastroesophageal Reflux Disease, Abdominal Pain
- Trial name
- NCT00521703
- Testing
- Lidocaine, Tannic acid
- Where
- Brazil
- Volunteers
- 78 people
- Sponsor
- Hospital Infantil Cândido Fontoura
Hiatus Hernia
Prevalence of Hiatus Hernia in Gastro-Esophageal Reflux Disease Patients Underwent Upper Endoscopy
To study the prevalence of hiatus hernia in GERD patients underwent upper endoscopy To study the effect of hiatus hernia on the severity of GERD symptoms.
- Trial name
- NCT06155851
- Testing
- Upper Endoscopy
- Volunteers
- 100 people
- Sponsor
- Assiut University
Diagnostic Esophagogastroduodenoscopy
Premedication With Alprazolam and Midazolam for Upper Gastrointestinal Endoscopy
Diagnostic upper GI endoscopy can be uncomfortable and stressful for many patients. Various methods are available for sedation during this procedure.
- Trial name
- NCT03130842
- Testing
- Sublingual alprazolam, Oral midazolam
- Where
- Iran
- Volunteers
- 136 people
- Sponsor
- Isfahan University of Medical Sciences
Upper Gastrointestinal Bleeding
Single-use Versus Reusable Gastroscopes in Patients With Upper Gastrointestinal Bleeding.
Controlled-randomized trial evaluating single-use versus reusable gastroscopes in patients with upper gastrointestinal bleeding.
- Trial name
- OneScopeII (NCT06192355)
- Testing
- Endoscopic hemostasis using a Esophagogastroduodenoscopy
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- University Hospital Augsburg
Early Gastric Cancer, Barrett Esophagus
Linked Color Imaging vs White Light Imaging for Detection of Gastric Cancer Precursors
This study aims to examine the use of Linked Color Imaging in detection of gastric cancer precursors, as well as oesophageal and duodenal lesions.
- Trial name
- NCT03990025
- Testing
- Linked Color Imaging, White Light Imaging
- Where
- 2 sites in Singapore
- Volunteers
- 90 people
- Sponsor
- Changi General Hospital
Acute Pancreatitis (AP)
ENDoscopic Assessment in Acute PANcreatitis Study (ENDOPAN Study)
This is a prospective observational cohort study designed to evaluate early upper gastrointestinal endoscopic findings in adult patients hospitalized with acute pancreatitis.
- Trial name
- NCT07714850
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- Jan Kochanowski University
Gastrointestinal Diseases
Propofol Versus Midazolam in Sedation for Upper and Lower Gastrointestinal Endoscopy.
There has been rapid growth in the number and complexity of gastrointestinal (GI) endoscopic procedures performed during the last decade.
- Trial name
- NCT06358131
- Testing
- Endoscopy
- Where
- 2 sites in Egypt
- Volunteers
- 656 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Bleeding Peptic Ulcer, Active Bleeding
Urgent vs. Early Endoscopy in High Risk Patients With Upper Gastrointestinal Bleeding (UGIB)
Acute upper gastrointestinal bleeding (UGIB) is one of the commonest medical emergencies. The condition accounts for 150 per 100,000 populations. A National United Kingdom reported a crude overall mortality rate of 10%.
- Conditions
- Bleeding Peptic Ulcer, Active Bleeding, Gastrointestinal Bleeding
- Trial name
- NCT01675856
- Testing
- Urgent endoscopy, Early endoscopy
- Where
- China
- Volunteers
- 516 people
- Sponsor
- Chinese University of Hong Kong
Upper Gastrointestinal Bleeding, Gastro Intestinal Bleeding
Pediatric Acute Gastrointestinal Bleeding Registry
The goal of this study is to identify significant clinical and laboratory risk factors in pediatric patients with significant upper gastrointestinal bleeding.
- Trial name
- TRIAGE (NCT03090945)
- Testing
- This is an obsevational cohort study
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Boston Children's Hospital
Esophageal Varices, Portal Hypertension
Non-invasive Predictors of Esophageal Varices and Their Correlation to Upper Endoscopic Findings
The goal of this observational study: To evaluate the diagnostic accuracy of non-invasive markers in predicting the presence and grading of esophageal varices in children with portal hypertension.
- Trial name
- NCT07464522
- Volunteers
- 51 people
- Sponsor
- Assiut University
Foreign Body Ingestion
A Novel Strategy for Endoscopic Dual-instrument Retrieval of Upper GI Foreign Body
We describe a single-center, retrospective case series (n = 10) for the utilization of dual instruments to extract foreign body at physiological narrowing.
- Trial name
- NCT07649382
- Where
- China
- Volunteers
- 10 people
- Sponsor
- Shanghai Zhongshan Hospital
Hypoxia
Comparison of Hypoxia Between HFNC and SNC in Patient Undergoing UGI Endoscopic Procedures in Deep Sedation
Hypoxia frequently occurs as a complication during upper gastrointestinal endoscopic procedures performed under deep sedation. Traditional oxygen delivery methods, such as the simple nasal cannula, are commonly used to prevent…
- Trial name
- NCT06482879
- Testing
- Oxygen delivery
- Where
- Nepal
- Volunteers
- 122 people
- Sponsor
- National Academy of Medical Sciences, Nepal
Anxiety
Acupuncture Treatment in Adults Undergoing Diagnostic OGD : A Double-Blind Placebo Controlled Randomized Trial
To find out how the application of acupuncture needles to the proposed acupuncture points: Heart 7 (HT 7) and Pericardium 6 (PC 6) for reducing anxiety during Esophago-gastro-duodenoscopy (EGD)
- Trial name
- NCT00449241
- Testing
- Acupuncture
- Where
- China
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Anesthesia
Intranasal Dexmedetomidine Versus Intranasal Midazolam as a Premedication in Pediatrics Undergoing Upper GI Endoscopy
compare the effectiveness of intranasal dexmedetomidine and midazolam as a premedication in sedation of preschool children in GI endoscopy
- Trial name
- NCT06181682
- Testing
- Dexmedetomidine, Midazolam
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Obstructive Sleep Apnea
Assessment of the Effect of Hypoglossal Nerve Stimulation Therapy on Upper Airway Collapsibility During Drug-induced Sleep Endoscopy
This clinical trial will evaluate the effect of treatment with hypoglossal nerve stimulation on the underlying mechanisms of obstructive sleep apnea.
- Trial name
- HNS-CoDSE (NCT07337239)
- Testing
- Additional measurements during clinical standard follow-up drug-induced sleep endoscopy (DISE)
- Where
- Belgium
- Volunteers
- 21 people
- Sponsor
- University Hospital, Antwerp