Clinical trials: Ultrasonography, Interventional
Breast Cancer
Prospective Ultrasound Data Collection Study for AI-Based Detection of Breast Biopsy Markers
The goal of this observational study is to collect ultrasound imaging data to support the development and refinement of an artificial intelligence (AI)-enhanced ultrasound software designed to detect and localize standard-of-care…
- Trial name
- NCT07427407
- Testing
- Breast Ultrasound Imaging With Investigational AI Software
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- AURA Health Technologies
Coronary Artery Disease, Coronary Artery Disease Risk High
IVUS CHIP UPP Registry
The IVUS CHIP UPP Registry is a prospective, observational, multicenter, single-arm registry. A total of 1010 patients with complex coronary lesions will be enrolled in up to 2 years, with at least 500 men and women.
- Conditions
- Coronary Artery Disease, Coronary Artery Disease Risk High, Complex Coronary Artery Disease
- Trial name
- NCT06625801
- Testing
- IVUS
- Where
- 18 sites in United States
- Volunteers
- 1,010 people
- Sponsor
- ECRI bv
Jejunostomy; Complications, Enteral and Supplement Feeds Adverse Reaction
Clinical Pilot Study of the Percutaneous Ultrasound Jejunostomy Procedure
The purpose of this study is to evaluate the feasibility and performance of the Percutaneous Ultrasound Jejunostomy (PUJ) procedure that utilizes a novel device (PUMA-J System) in conjunction with widely available ultrasound…
- Conditions
- Jejunostomy; Complications, Enteral and Supplement Feeds Adverse Reaction, Safety Issues
- Trial name
- NCT06095804
- Testing
- Percutaneous Ultrasound Jejunostomy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- CoapTech
Percutaneous Access
Feasibility of Robotic Instrument Guidance System to Perform Safe Ultrasound-Guided Percutaneous Procedures During Routine Medical Procedures.
The Mendaera Guidance System ("Study Device") is intended to provide guidance for precise instrument placement of common percutaneous devices by positioning the device relative to the ultrasound transducer and the resulting image…
- Trial name
- ACCESS (NCT07358351)
- Testing
- Mendaera Guidance System
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Mendaera, Inc
Cataract
Cataract Surgery: Femto LDV Z8 Versus Conventional
The aim of the study is to demonstrate the performance and safety of the Femtosecond laser-assisted anterior capsulotomy and lens fragmentation on human eyes using the FEMTO LDV Z8 compared to conventional technique in cataract…
- Trial name
- COMFORT (NCT02351271)
- Testing
- Femto LDV Z8, Manual capsulorhexis&lens fragmentation
- Volunteers
- 130 people
- Sponsor
- Ziemer Ophthalmic Systems AG
Complex Coronary Lesions
Intravascular Ultrasound Guidance for Complex High-risk Indicated Procedures
The IVUS CHIP trial is a post-marketing strategy study in which patients with complex coronary lesions, undergoing percutaneous coronary intervention (PCI), are treated either with intravascular ultrasound (IVUS) guided PCI or…
- Trial name
- IVUS-CHIP (NCT04854070)
- Testing
- IVUS, Angio
- Where
- 37 sites in Belgium, France and 5 more
- Volunteers
- 2,020 people
- Sponsor
- ECRI bv
Iliac Venous Compression
Venogram vs. Intravascular Ultrasound (IVUS) for Diagnosing Iliac Vein Obstruction
The purpose of this study is to demonstrate that IVUS identifies more instances of significant iliac and common femoral vein outflow obstruction than multiplanar venography.No hypothesis testing is planned.
- Trial name
- VIDIO (NCT02142062)
- Where
- 14 sites in United States, Italy and 2 more
- Volunteers
- 100 people
- Sponsor
- Volcano Corporation
Venous Ulcer of Leg
Intravascular Ultrasound-Guided Intervention for Venous Leg Ulcers (IGuideU)
This clinical study is a global, prospective, multi-center, randomized controlled trial to determine if the use of intravascular ultrasound (IVUS) as an adjunctive imaging modality and as an interventional treatment guide will…
- Trial name
- IGuideU (NCT04696354)
- Testing
- IVUS, Continued Compression Therapy/Stockings
- Where
- 17 sites in United States, Australia and 3 more
- Volunteers
- 12 people
- Sponsor
- Philips Clinical & Medical Affairs Global
Structural Cardiac Defects
Three-dimensional (3D) Holographic Display for Ultrasound-Guided Structural Heart Disease Procedures
This study is intended to evaluate the use of the holographic display of 3D images acquired during ultrasound based cardiac procedures and to assess the clinical use of the HOLOSCOPE-i, in providing 3D spatial understanding to…
- Trial name
- NCT05514626
- Testing
- 3D Holographic Display
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- RealView Imaging
Haemophilia A (Moderate or Severe), Hemophilia, Classic
A Study to Investigate the Course of Synovial Hypertrophy in Patients With Haemophilia A on Efanesoctocog Alfa Prophylaxis
The rationale for conducting this open-label phase 4 study is to assess whether once-weekly prophylaxis with efanesoctocog alfa (50 IU/kg) improves the disease course of existing synovial hypertrophy and prevents the risk of…
- Conditions
- Haemophilia A (Moderate or Severe), Hemophilia, Classic, Haemophilia, Hemophilia
- Trial name
- NCT06752850
- Testing
- Efanesoctocog alfa
- Where
- 10 sites in Italy, Norway and 2 more
- Volunteers
- 37 people
- Sponsor
- Swedish Orphan Biovitrum
Physiologic Venous Dilation, Air Travel
Prospective Repeated-Measures Study of Popliteal Vein Diameter During the First 48 Hours After Commercial Air Travel to Bogota for a Plastic Surgery Intervention
This prospective repeated-measures study will evaluate how long popliteal vein dilation persists after international commercial air travel to Bogota.
- Trial name
- NCT07808411
- Testing
- Commercial Air Travel Exposure, Standardized Bilateral Popliteal Vein Duplex Ultrasound
- Where
- Colombia
- Volunteers
- 100 people
- Sponsor
- Research Inc
Structural Heart Diseases, Atrial Septal Defect
Cardiac Interventional ICE Imaging Trial
The INTELICE trial is a prospective, multicenter, 1:1 randomized controlled non-inferiority study. It aims to compare a novel intracardiac echography (ICE) catheter and combined ultrasound system with existing commercial ones.
- Conditions
- Structural Heart Diseases, Atrial Septal Defect, Patent Foramen Ovale, Arrhythmias, Cardiac
- Trial name
- INTELICE (NCT06344494)
- Testing
- Arch EchoTM Intracardiac Ultrasound catheter and ultrasound system, SOUNDSTAR 3D Diagnostic Ultrasound catheter and ACUSON P500 system
- Where
- 4 sites in China
- Volunteers
- 130 people
- Sponsor
- ICE Intelligent Healthcare Co., Ltd
Image-Guided Biopsies and/or Ablations
Comparison of a Novel Ultrasound System Versus Standard Imaging Modalities
This is an observational study comparing a novel ultrasound-based imaging system (MAUI K3900) to standard-of-care (SoC) imaging systems used to guide and/or manage interventional radiologic procedures such as solid organ biopsies…
- Trial name
- NCT05748106
- Testing
- Ultrasound-based imaging
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- MAUI Imaging, Inc.
CT Guided Biopsy, CT Guided Drain Placement Within the Abdomen or Pelvis
Ultrasound-CT Fusion System for Interventional Radiology Procedures
The objective of this research is to use the Clear Guide SCENERGY technology, an FDA approved Ultrasound-CT fusion imaging system, that allows the user to fuse CT images onto a real-time ultrasound that is being performed on the…
- Conditions
- CT Guided Biopsy, CT Guided Drain Placement Within the Abdomen or Pelvis, CT Guided Injection of Muscle or Nerve Within the Pelvis
- Trial name
- NCT03226535
- Testing
- Ultrasound-CT Fusion
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Clear Guide Medical
Cosmetic Surgery
Effectiveness Study of MIST Therapy After Cosmetic Surgery Procedures of the Face and Body
A clinical trial to evaluate the effect of MIST Therapy on outcomes after cosmetic procedures(including facelifts, blepharoplasties, breast augmentations and reductions, mastopexies, and abdominoplasties) traditionally associated…
- Trial name
- NCT01206855
- Testing
- MIST Therapy, Standard Postoperative Incision Care
- Where
- United States
- Volunteers
- 3,440 people
- Sponsor
- Celleration, Inc.
Learning Anesthesia Procedures
Training and Evaluation of Ultrasound-Guided Procedures
38 certified registered nurse anesthetist (CRNA) students will learn 5 different ultrasound-guided regional anesthesia blocks both with and without a novel device, the EDU which gives the student help finding the right needle…
- Trial name
- NCT05889923
- Testing
- With EDU
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Clear Guide Medical
Cardiovascular Diseases, Arrhythmias, Cardiac
Intracardiac Echocardiography Catheter Supply-Chain Reliability and Clinical Access Study
The ICE-ACCESS study is a prospective observational study designed to evaluate how procurement reliability, distribution restrictions, supply-chain interruptions, and device availability affect access to intracardiac…
- Conditions
- Cardiovascular Diseases, Arrhythmias, Cardiac, Atrial Fibrillation
- Trial name
- ICE-ACCESS (NCT07788040)
- Testing
- Intracardiac Echocardiography Catheter
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Truway Health, Inc.
Primary Parathyroid Adenomas
Observation of Histological Changes in Parathyroid Adenomas Following High Intensity Focused Ultrasound (HIFU) Treatment Procedure
This study is a multicentre, open, uncontrolled trial for the observation of histological changes in parathyroid adenomas following high intensity focused ultrasound (HIFU).
- Trial name
- NCT01060982
- Testing
- Ultrasonic ablation device
- Where
- 2 sites in France
- Volunteers
- 5 people
- Sponsor
- Theraclion
Solid Tumor, Colorectal Cancer
PS101-mediated ACT With Chemotherapy in Liver Metastases From Cancer of Gastrointestinal Origin
Part 1: This clinical study will first test the safety and initial effect on the tumour of PS101-mediated ACT when given in combination with standard of care chemotherapy in patients with liver metastases (initially those with…
- Trial name
- ACT (NCT04021277)
- Testing
- 20 uL/kg PS101, 40 uL/kg PS101, Ultrasound
- Where
- 4 sites in Norway, United Kingdom
- Volunteers
- 11 people
- Sponsor
- EXACT Therapeutics AS
Uncontrolled Hypertension
Feasibility Study of Renal Denervation for the Treatment of Resistant Hypertension
The aim of this study is to assess the potential therapeutic benefit of catheter-based renal sympathetic denervation using therapeutic unfocussed ultrasound in a single-arm feasibility trial.
- Trial name
- SoundITV (NCT01865591)
- Testing
- Ultrasound-based Renal Denervation
- Where
- Czechia
- Volunteers
- 30 people
- Sponsor
- Sound Interventions, Inc.