Clinical trials: Ulcerative Colitis in Remission
Ulcerative Colitis, Crohn's Disease
Probiotics in GastroIntestinal Disorders
All of us have millions of bacteria living in our gut. These bacteria are very important to our health providing us with protection against infections of the gut, allowing us to gain extra nutritional value from food we eat and…
- Trial name
- PROGID (NCT00510978)
- Testing
- Bifidobacterium infantis 35624, Lactobacillus salivarius UCC118
- Where
- Ireland
- Volunteers
- 360 people
- Sponsor
- University College Cork
Ulcerative Colitis
Vedolizumab Monotherapy Vs Combination Therapy With Tacrolimus in UC
The aim of this study is to assess if a combination therapy of tacrolimus and vedolizumab is superior to vedolizumab monotherapy for induction of remission in moderate to severe UC, and its effect on long and short-term outcomes…
- Trial name
- COVET (NCT02954159)
- Testing
- Tacrolimus, Vedolizumab
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Medical College of Wisconsin
Ulcerative Colitis
Diet Treatment of Patients With Ulcerative Colitis in Remission
The study examines the effect of a low FODMAP diet in patients with UC in remission but still having GI symptoms (IBS in IBD). 15 patients will be on watchful waiting. 15 patients will be on low FODMAP diet.
- Trial name
- NCT02469220
- Testing
- Low FODMAP, Standardized FODMAP
- Where
- Denmark
- Volunteers
- 19 people
- Sponsor
- Regionshospital Nordjylland
Ulcerative Colitis
Mesalamine 4 g Sachet for the Induction of Remission in Active, Mild to Moderate Ulcerative Colitis (UC)
The purpose of this trial is to investigate the efficacy of mesalamine for the induction of clinical and endoscopic remission in subjects with active, mild to moderate UC.
- Trial name
- NCT02522767
- Testing
- Mesalamine
- Where
- 93 sites in United States, Bulgaria and 9 more
- Volunteers
- 228 people
- Sponsor
- Ferring Pharmaceuticals
Ulcerative Colitis
Study of Freeze-dried Black Raspberry in Maintenance of Ulcerative Colitis
This research study is about adding Black Raspberry powder to the treatment regimen of patients with ulcerative colitis who are currently in remission and doing well.
- Trial name
- BRB (NCT02267694)
- Testing
- Freeze-dried black raspberry powder
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- UConn Health
Ulcerative Colitis
Profermin® in Active Ulcerative Colitis
In this study the investigators aim was to investigate the safety and possible efficacy of Profermin® in patients with ulcerative colitis.
- Trial name
- CUPE-1 (NCT01245465)
- Testing
- Profermin
- Volunteers
- 39 people
- Sponsor
- Nordisk Rebalance A/S
Ulcerative Colitis
Efficacy and Safety of Adalimumab in Subjects With Moderately to Severely Active Ulcerative Colitis
This was a Phase 3, multicenter, randomized, double-blind, placebo-controlled trial designed to evaluate the efficacy and safety of the human anti-tumor necrosis factor (TNF) monoclonal antibody adalimumab (ADA) in patients with…
- Trial name
- NCT00408629
- Testing
- adalimumab
- Where
- 108 sites in United States, Argentina and 16 more
- Volunteers
- 518 people
- Sponsor
- Abbott
Crohn Disease, Ulcerative Colitis
5-HTP in Patients With IBD in Clinical and Biologic Remission:Effect on Fatigue Scores
This placebo cross-over trial aims to study the effect of the oral intake of an essential amino-acid 5-OH tryptophan, the precursor of serotonin, on the fatigue scores in IBD patients in deep clinical and biological remission.
- Conditions
- Crohn Disease, Ulcerative Colitis, Fatigue, Remission
- Trial name
- TRP-IBD (NCT03574948)
- Testing
- 5-HTP
- Where
- 13 sites in Belgium
- Volunteers
- 175 people
- Sponsor
- University Hospital, Ghent
Ulcerative Colitis (UC)
A Study to Evaluate the Effect of Fecal Transplant and Dietary Changes on Disease Activity in Patients With Newly Diagnosed Active Ulcerative Colitis
Ulcerative colitis (UC) is a chronic inflammatory condition affecting the colon and rectum, characterized by mucosal inflammation and symptomslike diarrhea, abdominal pain, and rectal bleeding.
- Trial name
- ALTER-UC (NCT06895252)
- Testing
- Anti inflammatory diet, Fecal Microbial Transplantation
- Where
- 6 sites in India
- Volunteers
- 220 people
- Sponsor
- All India Institute of Medical Sciences
Ulcerative Colitis
ChAracterizing the Remission Status in Patients With Ulcerative Colitis Treated by 5-ASA
For the last years the aim of the management of ulcerative colitis (UC) has become more ambitious including not only clinical remission but also the achievement of biological remission, endoscopic and histological healing, which…
- Trial name
- CARUC-ASA (NCT05992142)
- Testing
- 5-ASA
- Where
- 16 sites in Belgium
- Volunteers
- 200 people
- Sponsor
- Belgian Inflammatory Bowel Disease Research and Development (BIRD) VZW
Ulcerative Colitis, FMT
Refined Fecal Microbiota Transplantation (FMT) for Ulcerative Colitis (UC)
The researchers intend to prospectively study the safety, clinical efficacy and microbial outcomes in patients with recently diagnosed UC with FMT capsule therapy derived from pre-defined donors.
- Conditions
- Ulcerative Colitis, FMT, Fecal Microbiota Transplant
- Trial name
- REFOCUS (NCT04968951)
- Testing
- Metronidazole, Vancomycin, Fecal Microbiota Transplantation
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Ari M Grinspan
Ulcerative Colitis
Efficacy of Treatment With Berberine to Maintain Remission in Ulcerative Colitis
The research aim to find out whether berberine can reduce the annual recurrence rate of ulcerative colitis in remission. A total of 238 patients with ulcerative colitis in remission will be randomly divided into two groups.One…
- Trial name
- NCT02962245
- Testing
- berberine, regular treatment
- Sponsor
- Xijing Hospital of Digestive Diseases
Ulcerative Colitis in Remission
Effect of Procyanidins in Leaky Gut Repairing in IBD
The goal of this clinical trial is to learn if the Grape Seed Extract Ecovitis, featuring low monomeric catechins content and a high concentration of oligo-polymeric procyanidins, could modulate the Gut Microbiota composition of…
- Trial name
- EcoVitis (NCT06576700)
- Testing
- Grape Seed Extracts
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- University of Padova
Ulcerative Colitis
Fecal Biotherapy for the Induction of Remission in Active Ulcerative Colitis
Ulcerative colitis is a condition that mainly affects young adults where the lining of the bowel is inflamed causing bloody diarrhea.
- Trial name
- NCT01545908
- Testing
- Fecal transplant
- Where
- 2 sites in Canada
- Volunteers
- 130 people
- Sponsor
- Hamilton Health Sciences Corporation
Ulcerative Colitis
Methotrexate in Induction and Maintenance of Steroid Free Remission in Ulcerative Colitis
There are fewer therapeutic options for patients with active ulcerative colitis (UC) compared to patients with active Crohn's disease (CD) and the investigators are facing a persistent unmet need for additional effective and…
- Trial name
- Merit-UC (NCT01393405)
- Testing
- Methotrexate
- Where
- 31 sites in United States
- Volunteers
- 179 people
- Sponsor
- University of North Carolina, Chapel Hill
Ulcerative Colitis
LFMT vs Placebo in New Biologic Start for Ulcerative Colitis
To compare the safety and efficacy of concomitant LFMT versus placebo in UC patients who are starting vedolizumab or ustekinumab.
- Trial name
- NCT05327790
- Testing
- Lyophilized fecal microbiota (LFMT)
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- University of Alberta
Ulcerative Colitis
Study of Effects and of Modifications in Apoptosis Regulators Observed After Stopping 5-ASA Treatment in Patients With Inactive Ulcerative Colitis
Male or female, 18 years of age or older. Ulcerative Colitis described according usual criteria, diagnosed for at least 1 year. Oral maintenance treatment with 5-aminosalicylic acid (5-ASA) only for at least 3 months with a…
- Trial name
- NCT00209287
- Testing
- Observe patients with inactive ulcerative colitis
- Where
- France
- Volunteers
- 6 people
- Sponsor
- Ferring Pharmaceuticals
Ulcerative Colitis
Efficacy, Safety and Immunogenicity of the Proposed Biosimilar Vedolizumab PB016 in Comparison With Entyvio®
This is a multi-center, randomized, parallel arm, double-blind study with approximately 750 participants with moderately to severely active Colitis Ulcerosa randomized to receive either PB016 or Entyvio®
- Trial name
- UCESIVE (NCT05771155)
- Testing
- Intravenous (IV) infusions
- Where
- Georgia
- Volunteers
- 750 people
- Sponsor
- Polpharma Biologics S.A.
Ulcerative Colitis, Inflammatory Bowel Diseases
FMT for Remission of Active Ulcerative Colitis in Adults
The goal of this study is to establish the safety and effectiveness of lyophilized (LYO) fecal microbiota transplant (FMT) for treating ulcerative colitis (UC) in adults.
- Trial name
- NCT04202211
- Testing
- FMT oral, FMT enema
- Where
- 3 sites in Canada
- Sponsor
- University of British Columbia
Ulcerative Colitis
Ability to Maintain or Achieve Clinical and Endoscopic Remission With MMX Mesalamine Once Daily in Adults With Ulcerative Colitis
This study was designed to evaluate if subjects who achieve complete remission after 8 weeks of acute therapy with MMX mesalamine/mesalazine 4.8g/day given QD have better long-term outcomes and remain in remission longer compared…
- Trial name
- NCT01124149
- Testing
- MMX mesalamine/ mesalazine
- Where
- 105 sites in United States, Belgium and 13 more
- Volunteers
- 759 people
- Sponsor
- Shire