Clinical trials: Type1diabetes
Type1diabetes
Butyrate Adjuvant Therapy for Type 1 Diabetes
The investigators are interested to evaluate the effect of BKR-017 (colon-targeted 500 mg butyrate tablets) as adjuvant therapy on metabolic control in type 1 diabetes (TID) subjects.
- Trial name
- NCT03999853
- Testing
- BKR-017
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Type1diabetes
Evaluation of a Decision Support System for People With Diabetes Who Use Multiple Daily Insulin Injections- Feasibility and Proof of Concept Studies
The study comprises of two segments: a feasibility segment and a Proof of Concept segment. The study is open label, prospective study that will include up to 72 subjects in segment 1 and up to 40 subjects in segment 2.
- Trial name
- NCT04653961
- Testing
- DreaMed Advisor Pro DSS-MDI algorithm
- Where
- 2 sites in Israel
- Volunteers
- 48 people
- Sponsor
- Rabin Medical Center
Type1diabetes
Skeletal Fragility in Type 1 Diabetes: Glycemic Control and Bone Strength
The purpose of this research study is to find out how bones are affected in children and adolescents with type 1 diabetes (T1D) as compared to children and adolescents without type 1 diabetes.
- Trial name
- NCT04289727
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Columbia University
Type1diabetes
Home-HIT and Type 1 Diabetes
This study aimed to use a multi-disciplinary approach to evaluate a 6-week home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes.
- Trial name
- NCT03545802
- Testing
- Home-HIT
- Where
- United Kingdom
- Volunteers
- 11 people
- Sponsor
- Liverpool John Moores University
type1diabetes, Obesity
Physiologic Markers of Cardiometabolic Risk in People With Type 1 Diabetes
More than 40% of young adults with type 1 diabetes (T1D) also have overweight or obesity. Each of these diagnoses increase the risk of adverse cardiovascular events.
- Trial name
- NCT06105931
- Testing
- Hyperinsulinemic-euglycemic clamp, High Fat Mixed Meal Tolerance Test
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yale University
type1diabetes
Response to BNT162b2 Vaccine in Adolescents With Type 1 Diabetes
Adolescents with type 1 diabetes may be at increased risk for severe coronavirus disease-2019 (COVID-19) and are therefore prioritized for access to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination.
- Trial name
- NCT05620251
- Testing
- Blood test
- Where
- Turkey (Türkiye)
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- Istanbul Medeniyet University
Type1diabetes, Hypoglycemia
Galactose - the Ideal Carbohydrate Supplement for Exercise in Type 1 Diabetes
In this study, 14 subjects with type 1 diabetes are studied in a randomized crossover study in which the subjects cycle at a fixed intensity at 60% of their maximum oxygen capacity (VO2 max) for 1 hour.
- Conditions
- Type1diabetes, Hypoglycemia, Hyperglycemia
- Trial name
- NCT05557227
- Testing
- 1-hour cycling
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- University of Aarhus
Type1diabetes
Development of Predictive Biomarkers
Investigators aim to further the understanding of the various factors that govern the progression of beta-cell death in individuals recently diagnosed with Type 1 diabetes (T1D).
- Trial name
- NCT03423862
- Testing
- Mixed Meal Tolerance Test
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medical College of Wisconsin
type1diabetes, Diabetes Mellitus, Type 1
A Fully Automated Lyumjev and Pramlintide Delivery System for Adults With Type 1 Diabetes
The aim of this clinical trial is to investigate whether a fully automated Lyumjev-and-pramlintide delivery system improves glycemic outcomes in adults with type 1 diabetes.
- Trial name
- FCL (NCT06046417)
- Testing
- Pramlintide, Lyumjev, Automated Insulin Delivery (AID) system
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Type1diabetes
Technical Evaluation Of JewelPUMP In Type 1 Diabetic Patients Treated With Extern Insulin Pump
The main objective of the study is to verify the reliability of the solutes volumes issued by the Debiotech JewelPUMPTM controlled by its remote.
- Trial name
- DIABELOOP (NCT01640210)
- Testing
- JewelPUMP (insulin patch pump)
- Where
- 2 sites in France
- Volunteers
- 28 people
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
Type1diabetes
New Insulin Therapy by Multiwave Bolus
The aim of the study is to evaluate the effect of insulin therapy when the bolus dose of insulin is calculated on the basis of protein and fat content in food intake, in addition to that of carbohydrates in T1D patients treated…
- Trial name
- EVANEWFIT2 (NCT03311516)
- Testing
- New functional insulin therapy, functional insulin therapy
- Where
- 6 sites in France
- Volunteers
- 150 people
- Sponsor
- Central Hospital, Nancy, France
Type1diabetes
Clinical Trial to Evaluate the Efficacy of the Smart Insulin Pen Compared to a Closed Loop System in Patients With Type 1 Diabetes (EBIACE-1)
Analysis of glycemic control, frequency of hypoglycemia, glycemic variability, patient satisfaction and patient-perceived quality of life in patients with type 1 diabetes mellitus and continuous real-time glucose monitoring, the…
- Trial name
- EBIACE-1 (NCT05708040)
- Testing
- InPen Medtronic, Minimed 780G system
- Where
- Spain
- Volunteers
- 48 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal
Type1diabetes, Celiac Disease
Newborn Screening for Genetic Susceptibility to Type 1 Diabetes and Celiac Disease and Prospective Follow-up Study
This is an observational study, in which newborn infants from the general population are screened at birth for HLA-conferred susceptibility to type 1 diabetes and celiac disease.
- Trial name
- BABYSCREEN (NCT04958356)
- Where
- Finland
- Volunteers
- 9,690 people, healthy volunteers welcome
- Sponsor
- University of Helsinki
Type1diabetes
Observational Study of the Use of DBLG1 System in Real Life
This study will be conducted on human subjects and is observational, prospective and uncontrolled, defined as a category 3 according to the Jardé Law (RIPH3). It is a national and multicentric study.
- Trial name
- SP12 (NCT04749693)
- Testing
- DBLG1 System
- Where
- 20 sites in France
- Volunteers
- 348 people
- Sponsor
- Diabeloop
Type1diabetes
Check It! 2.0: Positive Psychology Intervention for Adolescents With Type 1 Diabetes
The treatment regimen for type 1 diabetes is complex and demanding, and many adolescents have problems with adherence. The proposed study will pilot test a positive psychology intervention for adolescents with type 1 diabetes…
- Trial name
- NCT02984709
- Testing
- Positive Psychology Intervention, Education
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Vanderbilt University
Type1diabetes
HIT on Hypoglycemic Risk in Type 1 Diabetes (T1D)
There is clear evidence that regular exercise improves wellbeing and reduces the risk of diabetes related complications in people with type 1 diabetes. However, many people with type 1 diabetes do not exercise regularly.
- Trial name
- NCT03598400
- Testing
- high intensity interval training, moderate intensity continous training
- Where
- United Kingdom
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
Type1diabetes
Motivational Interviewing and Self-care in Type 1 Diabetes: Randomized Controlled Clinical Trial.
Type 1 diabetes requires a high level of involvement of patients to obtain good control by following complex therapeutic recommendations.
- Trial name
- NCT03906786
- Testing
- motivational interviewing
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Hospital Universitario Insular Gran Canaria
Type1diabetes, Type 2 Diabetes
Diabetes Registry Graz for Biomarker Research
The Diabetes registry for biomarker research Graz is a prospective cohort-study including subjects with type 1 and type 2 diabetes, rare types of diabetes, obesity and dyslipidemia, aiming to collect data, blood and urine samples…
- Conditions
- Type1diabetes, Type 2 Diabetes, Adiposity
- Trial name
- GIRO (NCT05324488)
- Testing
- No intervention
- Where
- Austria
- Volunteers
- 2,000 people
- Sponsor
- Medical University of Graz
type1diabetes
Type 1 Diabetes Virtual Self-management Education and Support
OVERVIEW: People living with type 1 diabetes (T1D) are expected to fit self-management and regular clinical consultations into busy lives.
- Trial name
- T1ME (NCT05756829)
- Testing
- High frequency, low touch virtual health care
- Where
- 9 sites in Canada
- Volunteers
- 580 people
- Sponsor
- Unity Health Toronto
Type1diabetes, Fatty Liver
Night Hyperglycemia and Fatty Liver in Type 1 Diabetes
This clinical trial aims to discover the relationship between hyperglycemia at night and early morning hours and the presence of fatty liver in patients with type 1 diabetes.
- Trial name
- NCT05933018
- Testing
- liver elastography
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- HaEmek Medical Center, Israel