Clinical trials: Type1diabetes
Type1diabetes
Safety and Efficacy of 7-day Wear Infusion Set vs. Control Infusion Set.
The purpose of this study is to evaluate the Extended Wear (EW) infusion set seven day functioning in patients with Type 1 diabetes compared to the Quick-set infusion set.
- Trial name
- NCT04208282
- Testing
- 7 day infusion set
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Sheba Medical Center
type1diabetes, Pediatrics
AI for Glycemic Events Detection Via ECG in a Pediatric Population
Paediatric Type 1 Diabetes (T1D) patients are at greater risk for developing severe hypo and hyperglycaemic events due to poor glycaemic control and incorrect Insulin administration.
- Trial name
- NCT05278143
- Where
- Italy
- Volunteers
- 64 people
- Sponsor
- Bambino Gesù Hospital and Research Institute
Type1diabetes, Pediatric ALL
CloudCare in the Treatment of Type 1 Diabetes in Pediatrics
This prospective cohort study aims to estimate the effect of the CloudCare application in daily practice on treatment satisfaction and emotional burden for pediatric patients and their parents/caregivers, patients' glycemic…
- Trial name
- NCT06018324
- Where
- Netherlands
- Volunteers
- 600 people
- Sponsor
- Diabeter Nederland BV
Type1diabetes, Type1 Diabetes Mellitus
Evaluation of Coffee Therapy for Improvement of Renal Oxygenation
Over 1.25 million Americans have Type 1 Diabetes (T1D), increasing risk for early death from cardiovascular disease (CVD). Despite advances in glycemic and blood pressure control, a child diagnosed with T1D is expected to live up…
- Conditions
- Type1diabetes, Type1 Diabetes Mellitus, Diabetic Kidney Disease, Juvenile Diabetes
- Trial name
- COFFEE (NCT03878277)
- Testing
- Starbucks® Cold brew - 325ml bottle
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Colorado, Denver
Type1diabetes
Fasted Exercise in People With Type 1 Diabetes
This study aims to compare the effect of a bout of high-intensity interval training (HIT) with a bout of moderate-intensity continuous training (MICT) on glucose concentrations over the subsequent 24h period.
- Trial name
- NCT03544684
- Testing
- Effects of the type of exercise on blood glucose concentrations
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Liverpool John Moores University
type1diabetes
Unannounced Meal Handling of Advanced Closed Loop Insulin Delivery in Monitored Condition
The study will follow participants for the periods of 3 months while using an advanced hybrid closed loop algorithm in free living conditions . Each period will have a different meal handling protocols.
- Trial name
- NCT04479826
- Testing
- Advanced hybrid closed loop system
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- Sheba Medical Center
type1diabetes, Renal Failure
Kidney Alone Versus Islet-After-Kidney in Type 1 Diabetic Kidney Transplant Recipient.
Islet transplantation is associated with a benefit on glycaemic control compared to optimized insulin therapy in recent clinical trials.
- Conditions
- type1diabetes, Renal Failure, End Stage Renal Disease
- Trial name
- KA-IAK (NCT05662267)
- Testing
- Pancreatic islet transplantation after kidney transplantation
- Where
- France
- Volunteers
- 327 people
- Sponsor
- University Hospital, Lille
Type1diabetes
Alleviating Carbohydrate-Counting Burden in T1DM Using Artificial Pancreas and Empagliflozin
One of the challenges in the design of the artificial pancreas (AP) is preventing postprandial hyperglycemia. Beyond algorithmic solutions, one countermeasure to postprandial hyperglycemia that may enhance performance of the AP…
- Trial name
- CLASS15 (NCT03510000)
- Testing
- Empagliflozin 25mg, Single hormone artificial pancreas, Meal strategies
- Where
- 3 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Type1diabetes
Mobile Physical Activity for Type 1 Diabetes
The study is the formative observation stage of behavioral intervention development. Sedentary adults with type 1 diabetes will be given access to a mobile application that incorporates biosensor feedback, teleconsultation, and…
- Trial name
- NCT04204733
- Testing
- Mobile application
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Yale University
Type1diabetes
REACHOUT Mental Health Support Mobile App
The purpose of this study is to investigate the effectiveness of participation in a 6-month peer-led mental health support program, delivered via a mobile app (REACHOUT), to adults with type 1 diabetes compared to a wait-list…
- Trial name
- NCT05668507
- Testing
- REACHOUT Virtual Mental Health Support
- Where
- Canada
- Volunteers
- 225 people
- Sponsor
- University of British Columbia
Type1diabetes, Fear of Hypoglycemia
Intervention to Reduce Fear of Hypoglycemia and Optimize Type 1 Diabetes Outcomes
The overall objective and Primary Aim of this Limited Competition: Small Grant Program (R03) is to address the critical need of identifying and decreasing fear of hypoglycemia, which will be accomplished by conducting a pilot…
- Trial name
- NCT03039933
- Testing
- Fear of Hypoglycemia, Treatment As Usual
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- University of Colorado, Denver
Type1diabetes
SGLT2i, Pioglitazone, and Ketone Production in T1D
Participants are being asked to be in a research study. Scientists do research to answer important questions which might help change or improve treatment of participants disease in the future.
- Trial name
- NCT07056699
- Testing
- Dapagliflozin 10mg Tab, Pioglitazone 15 MG and 30mg
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- The University of Texas Health Science Center at San Antonio
type1diabetes
Feasibility Trial of a Mindfulness Based Intervention in Youth With Type 1 Diabetes
Type 1 diabetes (T1D) is one of the most common chronic illnesses of childhood. The involved treatment regimen, including daily insulin administration/pump management, frequent blood glucose checks, and careful track-ing of food…
- Trial name
- BREATHE-T1D (NCT05268393)
- Testing
- BREATHE-T1D
- Where
- United States
- Volunteers
- 42 people
- Sponsor
- Children's National Research Institute
Type1diabetes
4T Sustainability Program
The goal of the 4T program is to implement proven methods and emerging diabetes technology into clinical practice to sustain tight glucose control from the onset of type 1 diabetes (T1D) and optimize patient-reported and…
- Trial name
- NCT06314048
- Testing
- CGM and RPM
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Stanford University
Type1diabetes
Glycemic Variations During the Menstrual Cycle in Women With Type 1 Diabetes
In clinical practice, women living with type 1 diabetes frequently report that insulin requirements change across the menstrual cycle. Consequently, glycemic fluctuations are observed.
- Trial name
- GLYMETY (NCT05258292)
- Testing
- Continuous glucose monitoring, Insulin, Premenstrual symptoms
- Where
- Canada
- Volunteers
- 86 people
- Sponsor
- Institut de Recherches Cliniques de Montreal
Non-Nutritive Sweetener, Type 1 Diabetes
Cardiometabolic Effects of Non-Nutritive Sweeteners (NNS) in Type 1 Diabetes (T1D)
This project will apply a novel non-nutritive sweetener (NNS) dietary assessment tool with measurement of circulating NNS levels in a pediatric population, allowing correlation of NNS exposure to clinically meaningful…
- Conditions
- Non-Nutritive Sweetener, Type 1 Diabetes, type1diabetes, Type 1 Diabetes Mellitus
- Trial name
- NCT07434544
- Testing
- Cherry Sports Drink
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Medical College of Wisconsin
Diabetic Pregnancy, Insulin Resistance
Metformin Use to Improve Pregnancy Outcome in Women With Type 1 Diabetes.
The study investigates whether additional metformin medication in combination with regular insulin treatment will decrease the need of insulin for women with diabetes mellitus type 1 during pregnancy.
- Conditions
- Diabetic Pregnancy, Insulin Resistance, Type1diabetes
- Trial name
- NCT03765359
- Testing
- metforminhydrochloride
- Where
- 5 sites in Finland
- Volunteers
- 101 people
- Sponsor
- Tampere University Hospital
Type1diabetes
Management of Prolonged Aerobic exeRcise in Patients With Type 1 Diabetes on Advanced Technologies
The purpose of this study is to compare three different therapeutic and nutritional approaches during a prolonged aerobic exercise in moderately active type 1 diabetes people using advanced technologies, to identify the best…
- Trial name
- MARTA-walk (NCT05936203)
- Testing
- Insulin therapy adjustment, Nutritional adjustment, Combination of strategies
- Where
- Italy
- Volunteers
- 18 people
- Sponsor
- Federico II University
Diabetes Mellitus, Type 1, Type1diabetes
Group Education Trial to Improve Transition in Type 1 Diabetes
The investigators will conduct a randomized controlled trial (RCT) to examine group education visits as an innovative and potentially cost-effective approach to transition care delivery, that can be easily integrated into usual…
- Conditions
- Diabetes Mellitus, Type 1, Type1diabetes, Insulin Dependent Diabetes
- Trial name
- GET-IT-T1D (NCT03703440)
- Testing
- Active arm, Control arm
- Where
- 2 sites in Canada
- Volunteers
- 212 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Type1diabetes
Transition to Adult Care in Type 1 Diabetes
Successful transition to an adult diabetes clinic is an essential part of both clinical and psychosocial care for emerging adults with type 1 diabetes (T1D).
- Trial name
- NCT03886974
- Where
- United States
- Volunteers
- 260 people
- Sponsor
- Hoag Memorial Hospital Presbyterian