Clinical trials: Type 2 Diabetes Treated With Insulin
Diabetes Mellitus, Type 2
A Research Study to See How Well the New Weekly Medicine IcoSema, Which is a Combination of Insulin Icodec and Semaglutide, Controls Blood Sugar Level in People With Type 2 Diabetes Compared to Weekly Insulin Icodec
This study will compare the new medicine IcoSema, which is a combination of insulin icodec and semaglutide, taken once a week, to insulin icodec taken once a week in people with type 2 diabetes.
- Trial name
- COMBINE 1 (NCT05352815)
- Testing
- IcoSema, Insulin icodec
- Where
- 281 sites in United States, Australia and 20 more
- Volunteers
- 1,291 people
- Sponsor
- Novo Nordisk A/S
Diabetes, Diabetes Mellitus, Type 2
Effect of Liraglutide on Blood Glucose Control in Subjects With Type 2 Diabetes
This trial is conducted in Africa, Asia, Europe and South America. This trial is designed to show the effect of treatment with liraglutide added to existing glimepiride and metformin combination therapy and to compare it with the…
- Trial name
- LEAD-5 (NCT00331851)
- Testing
- liraglutide, insulin glargine, metformin
- Where
- 116 sites in Argentina, Austria and 16 more
- Volunteers
- 584 people
- Sponsor
- Novo Nordisk A/S
Diabetes, Diabetes Mellitus, Type 2
Observational Study to Evaluate the Safety and Efficacy of Levemir® in Type 2 Diabetes
This study is conducted in Africa. The aim of this study is to assess the safety and efficacy of Levemir® treatment for insulin naive patients with type 2 diabetes under normal clinical practice conditions in Algeria.
- Trial name
- IDEALS (NCT00700830)
- Testing
- insulin detemir
- Where
- Algeria
- Volunteers
- 1,976 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes
FreeStyle Libre- Effect on QOL in Type 2 Diabetes Patients
This is a randomized controlled study in type 2 diabetic patients who are presently uncontrolled on at least 2 injections of insulin daily with an A1C >7.5 % and <10%.
- Trial name
- NCT02809365
- Testing
- FreeStyle Libre, personal glucometer
- Where
- 2 sites in Israel
- Volunteers
- 100 people
- Sponsor
- Wolfson Medical Center
Diabetes Mellitus
Safety and Efficacy Study of Alogliptin on Glycemic Control in Subjects With Type 2 Diabetes.
The purpose of this study is to determine the safety and efficacy of alogliptin, once daily (QD), compared to diet and exercise, sulfonylurea, metformin and a combination of sulfonylurea and metformin for treating subjects with…
- Trial name
- NCT00755846
- Testing
- Alogliptin
- Volunteers
- 265 people
- Sponsor
- Takeda
Type 2 Diabetes, Type 2 Diabetes Treated With Insulin
Anxiety Reduction in Type 2 Diabetes Through Breathing ExercisesPatients With Type 2 Diabetes
Injection-related anxiety is a significant barrier to the management of type 2 diabetes, adversely affecting treatment adherence and glycemic control.
- Trial name
- NCT06519903
- Testing
- BREATH technique
- Where
- Turkey (Türkiye)
- Volunteers
- 65 people
- Sponsor
- Goztepe Prof Dr Suleyman Yalcın City Hospital
Type 2 Diabetes Treated With Insulin
In-Home Study With MiniMed™ 780G Pump Automated Control in Type 2-Evaluation of the AHCL System in Adults With Insulin-requiring Type 2 Diabetes
The objective of the study is to assess the safety and effectiveness of MiniMed™ 780G system in adult subjects with insulin-requiring type 2 diabetes in a home setting.
- Trial name
- NCT05238142
- Testing
- MiniMed™ 780G Insulin Pump system
- Where
- 31 sites in United States
- Volunteers
- 574 people
- Sponsor
- Medtronic MiniMed, Inc.
Type 2 Diabetes Treated With Insulin
C-peptide Concentrations in Type 2 Diabetes Treated With Insulin; is it Time to Revise the Treatment of Type 2 Diabetes
C-peptide is used to evaluate beta cell reserves. Patients with type 2 diabetes are treated with insulin for different indications.
- Trial name
- NCT04005261
- Testing
- C-peptide concentrations
- Where
- Turkey (Türkiye)
- Volunteers
- 249 people
- Sponsor
- Goztepe Training and Research Hospital
Diabetes, Diabetes Mellitus, Type 2
Comparing Efficacy and Safety of Insulin Detemir Plus Insulin Aspart and NPH Insulin Plus Human Soluble Insulin With or Without Metformin in Chinese Patients With Type 2 Diabetes
This trial is conducted in Asia. The aim of this trial is to compare efficacy and safety of insulin detemir plus insulin aspart and NPH insulin plus human soluble insulin both in a basal bolus regimen with or without metformin in…
- Trial name
- NCT01486966
- Testing
- insulin detemir, insulin aspart, insulin NPH
- Where
- 6 sites in China
- Volunteers
- 58 people
- Sponsor
- Novo Nordisk A/S
Type 1 Diabetes, Type 2 Diabetes
Comparison of Insulin Pump and MDI for Pregestational Diabetes During Pregnancy
This study is investigating whether insulin treatment with the insulin pump or with multiple daily injections (MDI) gives better outcomes for mother and baby in pregnant women with pregestational diabetes.
- Conditions
- Type 1 Diabetes, Type 2 Diabetes, Pregnancy
- Trial name
- NCT02064023
- Testing
- insulin pump, multiple daily insulin injection
- Where
- 2 sites in Canada
- Volunteers
- 2 people
- Sponsor
- University of British Columbia
Type 2 Diabetes Mellitus
Effects of Miglitol on Daily Plasma Glucose in type2 Diabetes Treated With Insulin
In this study, the effect of miglitol on daily plasma glucose will be evaluated in type 2 diabetic patients treated with insulin.
- Trial name
- NCT00213122
- Testing
- miglitol
- Where
- Japan
- Sponsor
- Sanwa Kagaku Kenkyusho Co., Ltd.
Type 2 Diabetes Mellitus
Effect of Exenatide Plus Metformin vs. Insulin Aspart Plus Metformin on Glycemic Control and Hypoglycemia in Patients With Type 2 Diabetes
This study in Germany is designed to compare the effects of twice-daily exenatide plus metformin and twice-daily premixed human insulin aspart plus metformin with respect to glycemic control, as measured by HbA1c, combined with…
- Trial name
- NCT00434954
- Testing
- exenatide twice daily (BID), premixed insulin aspart twice daily (BID)
- Where
- 39 sites in Germany
- Volunteers
- 494 people
- Sponsor
- AstraZeneca
Diabetes, Autoimmune, Diabetes Mellitus, Adult-Onset
Early Insulin Treatment in Patients With Latent Autoimmune Diabetes
Among adult patients diagnosed with type 2 diabetes, about 6% have autoantibodies directed against the insulin producing beta cells in the pancreas.
- Trial name
- NCT01109927
- Testing
- Insulin
- Volunteers
- 42 people
- Sponsor
- Lund University Hospital
Non-insulin-dependent Diabetes
Statin Compliance of Patients With Non-insulin-dependent Diabetes
The diabetic population has an increased cardiovascular risk compared to the general population. Hydroxymethylglutaryl-CoA reductase (HMG-CoA reductase) inhibitors, or "statins", are considered as the standard treatment for…
- Trial name
- DIOS (NCT04007133)
- Testing
- Girerd test
- Where
- France
- Volunteers
- 119 people
- Sponsor
- Lille Catholic University
Type 2 Diabetes Mellitus Without Insulin Treatment
Study to Compare the Effect of Vytorin (Simvastatin/Ezetimibe) 10/20mg Versus Atorvastatin 20mg on ApoB/ApoA1 Ratio in Subjects With Diabetes
A single center, open label, randomized, clinical trial comparing ApoB/ApoA ratio of Vytorin 10/20mg vs atorvastatin 20mg treatment. DM2 patients will be screened for inclusion criteria.
- Trial name
- NCT01185236
- Testing
- simvastatin/ezetimibe, atorvastatin 20mg
- Where
- South Korea
- Volunteers
- 132 people
- Sponsor
- Seoul National University Hospital