Clinical trials: Triglycerides
Mild Cognitive Impairment
Effect of Medium Chain Triglyceride Oil Supplementation in Mild Cognitive Impairment
The primary aim of this study is to assess whether daily dosing with medium chain triglycerides in subjects with mild cognitive impairment (MCI) will improve cognitive performance.
- Trial name
- NCT01669200
- Testing
- Medium Chain Triglyceride Oil
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Pennington Biomedical Research Center
Hypertriglyceridemia
Effect of Maraviroc on Metabolic Function in Obese Subjects (Phase I)
The purpose of this study is to determine the effect of maraviroc therapy in obese insulin resistant subjects on: 1. Plasma triglyceride concentration 2. Plasma HDL-cholesterol and LDL-cholesterol concentrations 3.
- Trial name
- NCT01133210
- Testing
- Maraviroc
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Washington University School of Medicine
Alzheimer's Disease
Medium Chain Triglycerides and Brain Metabolism in Alzheimer's Disease
Evaluate and compare the changes in brain ketone and glucose uptake after taking two different MCT oil emulsions (60-40 oil or C8 oil) for one month, in a group of people with Alzheimer's disease and a control group.
- Trial name
- MCT-MA (NCT02709356)
- Testing
- 1-month of 60-40 MCT oil, 1-month of C8 MCT oil
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Coronary Artery Disease, Diabetes
Homburg Cream & Sugar Study
The purpose of this study is to prospectivly analyze the correlation of triglyceride tolerance and glucose tolerance with cardiovascular morbidity and mortality in patients with stable coronary artery disease within 18 months and…
- Conditions
- Coronary Artery Disease, Diabetes, Metabolic Syndrome, Glucose Tolerance
- Trial name
- HCS (NCT00628524)
- Where
- Germany
- Volunteers
- 514 people
- Sponsor
- Universität des Saarlandes
Obesity
The Role of Brown Adipose Tissue in Triglyceride Clearance in People
The recent discovery of functional brown adipose tissue (BAT) in humans has led to a paradigm shift in adipose tissue biology; it is now believed that adipocytes may play a significant role in regulating substrate metabolism.
- Trial name
- BAT-TG (NCT02786251)
- Testing
- Cold exposure, Exposure to thermoneutral conditions
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Diabetes Mellitus, Type 2, Obesity
Culturally Adapted Dietary Clinical Trial in PR
This project will determine whether a diet culturally adapted to adults in Puerto Rico can effectively decrease cardiometabolic risk factors.
- Conditions
- Diabetes Mellitus, Type 2, Obesity, Hypertension, Dyslipidemias
- Trial name
- PRECISION (NCT05962372)
- Testing
- Culturally tailored food and diet advice, Standard healthy eating advice
- Where
- Puerto Rico
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Triglycerides
Curcumin & Astaxanthin for Lowering Triglyceride Readings and Inflammation
Two dietary supplements are each being compared to a placebo for the ability to help maintain triglycerides in the normal range. The subjects will be adult men and women with moderately high TG values.
- Trial name
- NCT07063056
- Testing
- Curcumin (Longvida™), Half Dose Curcumin (Longvida™), Astaxanthin
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Medinutra LLC
Major Cardiovascular Events
Impact of Triglyceride-Glucose Index on Cardiovascular Outcomes in Patients Presented With MINOCA
This work was designed to explore the role of the triglyceride-glucose (TyG) index in the prediction of cardiovascular outcomes in Patients Presented with myocardial infarction with nonobstructive coronary arteries.
- Trial name
- NCT06066177
- Testing
- Triglyceride glucose index TyG
- Volunteers
- 100 people
- Sponsor
- Assiut University
Absorption of Omega-3, Omega-3 Supplementation
A Study in Healthy Adults to Compare the Bioavailability of EPA + DHA From Two Microalgal Sources to One Fish Source and Placebo
This is a randomised, double-blind, parallel, placebo-controlled study in healthy adults to compare the absorption of two microalgal formulations, to a fish oil and a placebo.
- Conditions
- Absorption of Omega-3, Omega-3 Supplementation, Healthy Participants
- Trial name
- GOBO 2 (NCT07241377)
- Testing
- life'sTM omega O1035DS nTG, life'sTM omega O3020DS nTG, MEG-3 3323rTG
- Where
- Australia
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Obesity
Comparison of MAG and Fish Oil Efficacy
A potential application for unstructured monoacylglycerol (MAG) containing long chain polyunsaturated fatty acids (LC-PUFA)can be to provide essential fatty acids to humans who chronically consume lipases inhibitor such as…
- Trial name
- NCT01797757
- Testing
- Fish oil enriched with EPA, MAG-EPA oil, Orlistat
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Société des Produits Nestlé (SPN)
Healthy
Effect of MCT Emulsification on Ketogenesis in Human Adults
Lower brain glucose uptake is present before the onset of cognitive deterioration and may increase the risk of cognitive decline in Alzheimer's disease. Ketones are the brain's main alternative energy substrates.
- Trial name
- NCT02409927
- Testing
- MCT oil 10g, MCT homogenate 10g, Control
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Université de Sherbrooke
Healthy
Metabolic Effects of Honey or Fructose:Glucose Mixtures
The metabolic effects of 7-day weight-maintenance diets containing 10% total energy as acacia honey or a fructose:glucose mixture will be assessed in a group of healthy male volunteers.
- Trial name
- HONEY (NCT02747446)
- Testing
- added sugar
- Where
- Switzerland
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Luc Tappy, MD
Hypertriglyceridemia
A Phase 3 STudy of CaPRe in LOwering Very hiGh TriglYcerides (TRILOGY 2)
The primary objective of this study is to determine the efficacy of CaPre 4 g daily, compared to placebo, in lowering fasting TG levels in subjects with fasting TG levels ≥500 mg/dL and ≤1500 mg/dL (≥5.7 mmol/L and ≤17.0 mmol/L)…
- Trial name
- TRILOGY 2 (NCT03361501)
- Testing
- CaPre
- Where
- 68 sites in United States, Canada and 1 more
- Volunteers
- 278 people
- Sponsor
- Grace Therapeutics Inc.
Alzheimer's Disease, Primary Progressive Non-fluent Aphasia
A Medium Chain Triglyceride Intervention for Patients With Alzheimer Disease
The purpose of this study is to determine safety, tolerability, and pharmacokinetics/dynamics of a ketogenic dietary supplement containing medium chain triglycerides (MCTs) in patients with Alzheimer disease (AD).
- Conditions
- Alzheimer's Disease, Primary Progressive Non-fluent Aphasia, Frontotemporal Dementia (FTD)
- Trial name
- MINT-01 (NCT02912936)
- Testing
- Ketogenic medium chain triglyceride drink (MCT drink)
- Where
- Canada
- Volunteers
- 43 people
- Sponsor
- University of British Columbia
Atherosclerosis, Cardiovascular Diseases
Genetic and Environmental Determinants of Triglycerides (GOLDN)
To characterize the genetic basis of the variable response of triglycerides to two environmental contexts, one that raises triglycerides (dietary fat), and one that lowers triglycerides (fenofibrate treatment.)
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Heart Diseases
- Trial name
- NCT00083369
- Volunteers
- 1,327 people
- Sponsor
- University of Alabama at Birmingham
Healthy Adult Females
Postprandial Triglyceride Concentrations Across Menstrual Cycle Phases
The goal of this clinical trial is to investigate the effect of menstrual cycle phases on postprandial triglyceride concentrations in healthy young female adults.
- Trial name
- NCT07459465
- Testing
- Early Follicular Phase, Mid-Luteal Phase
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
Dyslipidemia
Study of Atorvastatin/Fenofibrate (LCP-AtorFen) Combination Therapy in Dyslipidemia
The current study is designed to test the efficacy, safety and tolerability of LCP-AtorFen, a combination of atorvastatin and fenofibrate.
- Trial name
- NCT00504829
- Testing
- LCP-AtorFen, atorvastatin, fenofibrate
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Veloxis Pharmaceuticals
Nutrition Disorder, Infant, Biliary Atresia
Nutritional Intervention for Biliary Atresia
Infants with biliary atresia (Biliary atresia, BA) have an increased risk of malnutrition due to insufficient dietary intake to maintain normal growth, impaired intestinal absorption, increased metabolic rate, and damage to some…
- Trial name
- NCT06764082
- Testing
- high MCT formula, normal oral intake of the traditional formula
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Tongji Hospital
Hyperlipidemias, Triglycerides High
Effects of MCDG Oil on Postprandial Lipid Metabolism
It is well known that medium chain triglycerides (MCTs) and diacylglycerols (DGs) have effects on lowering circulating triglycerides (TGs).
- Trial name
- NCT03415568
- Testing
- LCT oil, MCDG oil
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Fetal Macrosomatia, Lipid Metabolism Disorders
Influence of TyG Index and TG/HDL-C Ratio on Fetal Macrosomia
Metabolic disorders that can occur during pregnancy, in particular disorders of lipid metabolism and insulin resistance, can have a detrimental effect on pregnancy and the fetus.
- Conditions
- Fetal Macrosomatia, Lipid Metabolism Disorders, Hyperlipidemias
- Trial name
- NCT06463990
- Testing
- TyG index
- Where
- Turkey (Türkiye)
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- Ankara Etlik City Hospital