Clinical trials: Trigeminal Neuralgia
Trigeminal Neuralgia
An Evaluation of the Effect of a Surface Acoustic Wave Patch Device on the Symptons of Trigeminal Neuralgia
This is a double blinded randomized control trial of a Surface Acoustic Wave Patch device for the treatment of Trigeminal Neuralgia. This will be a crossover study for the group that receives the sham device.
- Trial name
- NCT02801630
- Testing
- PainShield SAW Patch Device
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Rosenblum, Jonathan I., DPM
Trigeminal Neuralgia
Randomized Study of L-Baclofen in Patients With Refractory Trigeminal Neuralgia
OBJECTIVES: I. Evaluate the efficacy of L-baclofen in patients with refractory trigeminal neuralgia. II. Evaluate the safety and tolerance of L-baclofen in these patients.
- Trial name
- NCT00004431
- Testing
- L-baclofen
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Primary Headache
Two US-guided Techniques for Greater Occipital Nerve Blocks
Headache is one of the most common reasons for patients to access healthcare. Greater occipital nerve (GON) block with local anesthetic and steroid has been described for the management of primary headache refractory to…
- Trial name
- GON (NCT02031822)
- Testing
- US-guided Greater Occipital Nerve Injection
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University Health Network, Toronto
Trigeminal Neuralgia (TN)
Neurophysiologic Signatures of Trigeminal Neuralgia Pain
Trigeminal neuralgia (TN) is an idiopathic pain disorder that is characterized by episodic attacks of intense facial pain, described as paroxysms of stabbing, electric, or explosive pain, and lasting for a few seconds or longer…
- Trial name
- NCT03778177
- Testing
- transcranial electrical brain stimulation
- Where
- 2 sites in United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Florida
Trigeminal Neuralgia
Classical Trigeminal Neuralgia and Sodium Channel Mutations
The most common cause of trigeminal neuralgia is considered to be a neurovascular contact. However, this etiological factor only seem to be present in half of the patient group. Thus the etiology of the other half is unknown.
- Trial name
- NCT03656497
- Testing
- Observational
- Volunteers
- 33 people
- Sponsor
- Danish Headache Center
Trigeminal Neuralgia
Botulinum Toxin for Trigeminal Neuralgia
Trigeminal neuralgia (TN) is one of the most painful and common types of neuropathic pain encountered by clinicians. It is typically treated pharmacologically with anticonvulsants,but these can be ineffective, or can lose their…
- Trial name
- EASTERN (NCT03331913)
- Testing
- Botulinum Toxin type A (intradermal / submucosal injection at pain area), Botulinum Toxin type A (intra-masseter injection on the ipsilateral of pain involved)
- Where
- 5 sites in China
- Volunteers
- 150 people
- Sponsor
- The First Affiliated Hospital of Zhengzhou University
Trigeminal Neuralgia
Comparison of Pulsed and Thermal Radiofrequency for Trigeminal Neuralgia
The goal of this clinical trial is to compare the effectiveness of Pulsed Radiofrequency (PRF) with Pulsed and Thermal Radiofrequency (PRF + TRF) in treating Trigeminal Neuralgia (TN) in adults.
- Trial name
- NCT06684275
- Testing
- Pulsed Radiofrequency (PRF), Pulsed and Thermal Radiofrequency (PRF + TRF)
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Zagazig University
Trigeminal Neuralgia
The Alternative Effects of Electroacupuncture in the Treatment of Trigeminal Neuralgia
Trigeminal neuralgia (TN), characterized by its refractory nature and recurrence, frequently leads to anxiety, depression, and insomnia, thereby significantly diminishing patients' quality of life and potentially inducing…
- Trial name
- NCT06977932
- Testing
- Carbarmazepine, Electroacupuncture
- Volunteers
- 126 people
- Sponsor
- Yuanyuan Wu
Trigeminal Neuralgia
Observational Study on the Treatment of Trigeminal Neuralgia by Radiosurgery
This study aims to evaluate the outcome of patient treated by radiosurgery on LINAC with high dose rate for classical trigeminal neuralgia
- Trial name
- NATURE (NCT05677243)
- Where
- Monaco
- Volunteers
- 150 people
- Sponsor
- Centre Hospitalier Princesse Grace
Trigeminal Neuralgia
Prognosis of Trigeminal Neuralgia When Enrolled in a Multidisciplinary Management Program
Background: Prognosis of medically treated trigeminal neuralgia patients is assumed to be poor, but the evidence is lacking. Thus, prospective real-life studies of medical management of trigeminal neuralgia are warranted.
- Trial name
- NCT03838393
- Testing
- multidisciplinary management
- Volunteers
- 186 people
- Sponsor
- Danish Headache Center
Inferior Alveolar Nerve Injuries, Impacted Third Molar Tooth
The Impact of 3D-CBCT Imaging on Nerve Injuries During Wisdom Tooth Surgery
The investigators aim to investigate if the additional information available from a 3D scan of the wisdom tooth can reduce the risk of nerve injury during wisdom tooth surgery compared to conventional 2D images.
- Trial name
- IMPACTION (NCT06261853)
- Testing
- 3D-CBCT, 2D-OPG
- Where
- 2 sites in United Kingdom
- Volunteers
- 1,292 people
- Sponsor
- University of Aberdeen
Trigeminal Neuralgia
Trigeminal Neuralgia Electrophysiology
The study intervention is to perform standard somatosensory evoked responses limited to the face during rhizotomy procedures of the gasserian ganglion (trigeminal ganglion) for the treatment of trigeminal neuralgia.
- Trial name
- NCT05269472
- Testing
- Trigeminal Electrophysiology
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Trigeminal Neuralgia
Comparing Clinical Benefits of Gamma Knife and Microvascular Decompression for Trigeminal Neuralgia
Clinical randomized study to compare the clinical effectiveness between two modalities of treatment of trigeminal neuralgia namely gamma knife radio surgery and microvascular decompression
- Trial name
- NCT03991039
- Testing
- Gamma knife
- Volunteers
- 84 people
- Sponsor
- University of Baghdad
Zoster; Herpes, Trigeminal Neuralgia (Etiology)
Esketamine Combined Pulsed Radiofrequency for Acute/Subacute Zoster-associated Trigeminal Neuralgia
To assess the 1-month effects and safety of esketamine combined PRF and standardized treatment to relieve pain in patients with acute/subacute zoster-related trigeminal neuralgia(ZRTN).
- Trial name
- NCT06890897
- Testing
- Esketamine group, PRF group
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Beijing Tiantan Hospital
Trigeminal Neuralgia
802NP301 Efficacy and Safety Study of BIIB074 in Participants With Trigeminal Neuralgia
The primary objective of the study is to evaluate the efficacy of BIIB074 in treating pain experienced by participants with trigeminal neuralgia (TN).
- Trial name
- SURGE-1 (NCT03070132)
- Testing
- BIIB074
- Sponsor
- Biogen
Trigeminal Neuropathy, Traumatic
Botulinum Toxin Injections for Oral Neuropathic Pain
Peripheral painful traumatic trigeminal neuropathy (PPTTN) are poorly relieved by existing treatments which in addition induce many adverse effects.
- Trial name
- TRIGTOX (NCT03555916)
- Testing
- BOTOX®, Allergan
- Where
- France
- Volunteers
- 43 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Inferior Alveolar Nerve Injuries
Risk of Nerve Damage After Administration of Local Anesthesia
This research aims to evaluate of the risk of nerve damage following the administration of articaine 4% and lidocaine 2% for Inferior Alveolar nerve Block (IANB).
- Trial name
- NCT06564987
- Testing
- 4% Articaine with 1:200,000 epinephrine, 2% lidocaine with 1:100,000 epinephrine
- Where
- 2 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cleveland Dental Institute
Trigeminal Neuralgia
Nasal Carbon Dioxide for the Symptomatic Treatment of Classical Trigeminal Neuralgia
A placebo-controlled, single-blind study to evaluate the safety and preliminary efficacy of nasal carbon dioxide for the symptomatic treatment of classical trigeminal neuralgia.
- Trial name
- NCT02473016
- Testing
- Carbon Dioxide Drug Delivery System (CDDS)
- Where
- 6 sites in United States
- Volunteers
- 30 people
- Sponsor
- Capnia, Inc.
Inferior Alveolar Nerve Injury, Nerve Injury
Platelet-rich Fibrin and Grooving for Sagittal Split Osteotomy
Sagittal split osteotomy (SSO) is a common operation done to move the mandible to correct dentofacial deformities and obstructive sleep apnea (OSA).
- Conditions
- Inferior Alveolar Nerve Injury, Nerve Injury, Neurosensory Disorder, Mandibular Nerve Injury
- Trial name
- NCT04706182
- Testing
- Platelet-rich fibrin (PRF), Proximal segment grooving (PSG)
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Jesse Han
Cluster Headache, Cluster Headaches and Other Trigeminal Autonomic Cephalgias
The Will Erwin Headache Research Center - Cluster Headache Study
The Will Erwin Headache Research Center Study of Cluster Headache and Trigeminal Neuralgia is a prospective, multicenter, observational research network for subjects with Cluster Headache and/or Trigeminal Neuralgia.
- Conditions
- Cluster Headache, Cluster Headaches and Other Trigeminal Autonomic Cephalgias, Paroxysmal Hemicrania, SUNCT
- Trial name
- WEC1 (NCT02910323)
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston