Clinical trials: Trigeminal Neuralgia
Trigeminal Neuralgia
Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion
The aim of this study is to assess the feasibility of deep brain stimulation for refractory trigeminal neuralgia due to a pontine lesion, as is usually seen in the context of multiple sclerosis.
- Trial name
- NCT05451251
- Testing
- Deep brain stimulation
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Université de Sherbrooke
Postherpetic Neuralgia, Peripheral Neuropathic Pain
Clinical Trial of the Safety and Efficacy of Peripheral Nerve Stimulation in the Treatment of Peripheral Neuropathic Pain.
The goal of this clinical trial is to evaluate safety and efficacy of percutaneous peripheral nerve stimulation in patients with peripheral neuropathic pain. The main questions it aims to answer are: 1.
- Conditions
- Postherpetic Neuralgia, Peripheral Neuropathic Pain, Trigeminal Neuralgia
- Trial name
- NCT06290661
- Testing
- Active electrostimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Trigeminal Neuropathy
Erenumab-aooe for the Management of Trigeminal Neuropathic Pain.
This study is a single center, placebo-controlled, double blind, randomized, phase II pilot to evaluate the efficacy of erenumab-aooe in the management of trigeminal neuropathic pain comparing erenumab-aooe vs Placebo.
- Trial name
- NCT05142228
- Testing
- Erenumab-Aooe
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Maryland, Baltimore
Trigeminal Neuralgia, Headache Disorders
Trigeminal Ganglion RFT vs Maxillary/Mandibular PRF in the Treatment of Trigeminal Neuralgia
Trigeminal ganglion (TG) radiofrequency thermocoagulation (RFT) and ultrasound (US)-guided maxillary or mandibular (max/mand) pulsed radiofrequency (PRF) are two interventional procedures for the treatment of trigeminal neuralgia…
- Trial name
- NCT06366139
- Testing
- Radiofrequency thermocoagulation of the trigeminal ganglion, Maxillary/Mandibular nerve pulsed radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Diskapi Teaching and Research Hospital
Trigeminal Neuralgia (Burchiel Type I), Trigeminal Neuralgia (Burchiel Type II)
Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain.
This study is an open-label study to determine the feasibility of Motor Cortex Stimulation (MCS) in the treatment of patients with chronic pain of the face or upper extremity.
- Conditions
- Trigeminal Neuralgia (Burchiel Type I), Trigeminal Neuralgia (Burchiel Type II), Trigeminal Neuropathic Pain, Trigeminal Deafferentation Pain
- Trial name
- NCT02321566
- Testing
- Epidural Motor Cortex Stimulation
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Johns Hopkins University
Stroke, Guillain-Barre Syndrome
Artificial Intelligence-powered Virtual Assistant for Emergency Triage in Neurology
This study examines the use of an AI-powered virtual assistant for quickly identifying and handling neurological emergencies, particularly in places with limited medical resources.
- Conditions
- Stroke, Guillain-Barre Syndrome, Facial Palsy, Migraine
- Trial name
- AIDEN (NCT06334796)
- Testing
- Virtual Assistant
- Where
- Argentina
- Volunteers
- 10 people
- Sponsor
- Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia
Trigeminal Neuralgia (TN)
Pulsed Radiofrequency Treatment Of the Gasserian Ganglion for tRigeminal nEuralgia: a retroSpective Study
With the Pulsed Radiofrequency treatment (PRF) Of the Gasserian ganglion for tRigeminal nEuralgia: a retroSpective Study (PROGRESS) the objective is to document the outcome of PRF (Pulsed Radiofrequency treatment) for patients…
- Trial name
- Progress (NCT06174818)
- Testing
- PRF
- Where
- Belgium
- Volunteers
- 85 people
- Sponsor
- Ziekenhuis Oost-Limburg
Facial Pain
Transcranial Stimulation (tDCS) For the Treatment of Neuropathic Facial Pain
A study to determine if transcranial direct current stimulation (tDCS, the device that regulates brain activity, can improve pain in people with neuropathic facial pain and compare which modality (inhibitory tDCS over the…
- Trial name
- TDCS (NCT01849796)
- Testing
- tDCS
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Beth Israel Medical Center
Trigeminal Neuralgia
Comparison of the Radiofrequency Treatments for the Treatment of Trigeminal Neuralgia.
The aim of this study is to compare the efficacy of radiofrequency of the Gasserian ganglion versus peripheral branches of the trigeminal nerve for the treatment of trigeminal neuralgia.
- Trial name
- NCT05516888
- Testing
- radiofrequency of gasserian ganglion, radiofrequency of the peripheral trigeminal branches
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Diskapi Teaching and Research Hospital
Cluster Headache, Cluster Headaches and Other Trigeminal Autonomic Cephalgias
The Will Erwin Headache Research Center - Cluster Headache Study
The Will Erwin Headache Research Center Study of Cluster Headache and Trigeminal Neuralgia is a prospective, multicenter, observational research network for subjects with Cluster Headache and/or Trigeminal Neuralgia.
- Conditions
- Cluster Headache, Cluster Headaches and Other Trigeminal Autonomic Cephalgias, Paroxysmal Hemicrania, SUNCT
- Trial name
- WEC1 (NCT02910323)
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Trigeminal Neuralgia
Efficacy and Tolerability of Erenumab in Patients With Trigeminal Neuralgia
A placebo-controlled, double-blind, randomized proof-of-concept study to evaluate the efficacy and tolerability of the CGRP receptor antibody erenumab in treating pain experienced by subjects with TN.
- Trial name
- NCT04054024
- Testing
- Erenumab
- Where
- Denmark
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Danish Headache Center
Trigeminal Neuralgia
Pulsed Radiofrequency in Trigeminal Neuralgia
The current study investigated the efficacy of pulsed radiofrequency in pain reduction in TN patients and compared the efficacy and the impact on the quality of life of the standard technique with a prolonged duration technique…
- Trial name
- NCT04355221
- Testing
- pulsed radiofrequency
- Volunteers
- 60 people
- Sponsor
- Mansoura University
Trigeminal Neuralgia, Microvascular Decompression
Impact of Teflon Technique on Recurrence After Microvascular Decompression for Trigeminal Neuralgia
The study aims to see if shredded Teflon placed away from the trigeminal nerve is equally effective in pain control in Trigeminal Neuralgia while minimizing the risks of pain recurrence due to granuloma formation when this…
- Conditions
- Trigeminal Neuralgia, Microvascular Decompression, Teflon
- Trial name
- NCT07046247
- Testing
- Microvascular decompression for trigeminal neuralgia
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- University of Valencia
Trigeminal Neuralgia
Comparision Efficacy of Carbamazepine & Oxcarbazepine in the Treatment of Trigeminal Neuralgia- a Randomised Clinical Trial
Trigeminal neuralgia is a neuropathic facial pain condition, characterized by unilateral paroxysmal pain which can be described as stabbing or electric shock like, in the distribution of one or more divisions of trigeminal nerve…
- Trial name
- NCT04996199
- Testing
- Oxcarbazepine, Carbamazepine
- Where
- 2 sites in India
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Postgraduate Institute of Dental Sciences Rohtak
Malaria
A Community Setting Study of Malaria After Systematic Treatment of Symptomatic Carriers of P. Falciparum With COA566 (Coartem®)
This study assessed the impact of the systematic detection by Rapid Diagnostic Test (RDT) and treatment of asymptomatic carriers of malaria parasites (P.
- Trial name
- NCT01256658
- Testing
- COA566
- Where
- 3 sites in Burkina Faso
- Volunteers
- 14,075 people
- Sponsor
- Novartis
Trigeminal Neuralgia
Comparative Study Between Transcoronoid and Infrazygomatic Anterior Maneuvers
new technique in targeting V2 under ultrasound guidance
- Trial name
- NCT05712993
- Testing
- V2 thermal radio frequency
- Where
- Iraq
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Iraqi Board of medical specialties
Trigeminal Neuralgia
Prognosis of Trigeminal Neuralgia When Enrolled in a Multidisciplinary Management Program
Background: Prognosis of medically treated trigeminal neuralgia patients is assumed to be poor, but the evidence is lacking. Thus, prospective real-life studies of medical management of trigeminal neuralgia are warranted.
- Trial name
- NCT03838393
- Testing
- multidisciplinary management
- Volunteers
- 186 people
- Sponsor
- Danish Headache Center
Trigeminal Neuralgia
High-intensity Laser Therapy Versus Low Level Laser Therapy in the Treatment of Trigeminal Neuralgia
Trigeminal neuralgia (TN) is the most common and severe type of neuropathic pain disorder affecting the orofacial region. It is characterized by sudden, intense, episodic attacks of pain in the distribution of trigeminal nerve…
- Trial name
- NCT07590414
- Testing
- 1064 nm Nd-YAG Laser, 940 nm Diode laser
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Alexandria University
Arteriovenous Malformation, Schwannoma
Hippocampal Radiation Exposure and Memory
Neurocognitive impairment as a result of gamma knife radiosurgery has not been well studied and is poorly understood. Radiosurgery to the base of skull for the treatment of benign and malignant disorders may consequently impair…
- Conditions
- Arteriovenous Malformation, Schwannoma, Trigeminal Neuralgia
- Trial name
- NCT00603694
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University Health Network, Toronto
Trigeminal Neuralgia
Research Study to Test Safety and Effectiveness of Investigational Drug in Patients With Trigeminal Neuralgia
This research study will look at the safety (e.g., the occurrence of side effects) and efficacy (how well the drug works in reducing trigeminal neuralgia attacks) of a drug called lamotrigine in adults with trigeminal neuralgia.
- Trial name
- NCT00203229
- Testing
- lamotrigine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Thomas Jefferson University