Clinical trials: Trigeminal Neuralgia
Trigeminal Neuralgia
The Alternative Effects of Electroacupuncture in the Treatment of Trigeminal Neuralgia
Trigeminal neuralgia (TN), characterized by its refractory nature and recurrence, frequently leads to anxiety, depression, and insomnia, thereby significantly diminishing patients' quality of life and potentially inducing…
- Trial name
- NCT06977932
- Testing
- Carbarmazepine, Electroacupuncture
- Volunteers
- 126 people
- Sponsor
- Yuanyuan Wu
Trigeminal Neuralgia, Trigeminal Nerve Diseases
Artificial Intelligence to Predict Surgical Outcomes and Assess Pain Neuromodulation in Trigeminal Neuralgia Subjects
Trigeminal neuralgia (TN) is the most common cause of facial pain. Medical treatment is the first therapeutic choice whereas surgery, including Gamma Knife radiosurgery (GKRS), is indicated in case of pharmacological therapy…
- Conditions
- Trigeminal Neuralgia, Trigeminal Nerve Diseases, Virtual Reality, Artificial Intelligence
- Trial name
- NCT05810428
- Testing
- GKRS-VR training, Control Group
- Where
- Italy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Cluster Headache, Cluster Headaches and Other Trigeminal Autonomic Cephalgias
The Will Erwin Headache Research Center - Cluster Headache Study
The Will Erwin Headache Research Center Study of Cluster Headache and Trigeminal Neuralgia is a prospective, multicenter, observational research network for subjects with Cluster Headache and/or Trigeminal Neuralgia.
- Conditions
- Cluster Headache, Cluster Headaches and Other Trigeminal Autonomic Cephalgias, Paroxysmal Hemicrania, SUNCT
- Trial name
- WEC1 (NCT02910323)
- Where
- United States
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Trigeminal Neuralgia, Microvascular Decompression
Impact of Teflon Technique on Recurrence After Microvascular Decompression for Trigeminal Neuralgia
The study aims to see if shredded Teflon placed away from the trigeminal nerve is equally effective in pain control in Trigeminal Neuralgia while minimizing the risks of pain recurrence due to granuloma formation when this…
- Conditions
- Trigeminal Neuralgia, Microvascular Decompression, Teflon
- Trial name
- NCT07046247
- Testing
- Microvascular decompression for trigeminal neuralgia
- Where
- Spain
- Volunteers
- 150 people
- Sponsor
- University of Valencia
Trigeminal Neuralgia, Glossopharyngeal Neuralgia
Anti-CGRP for Inflammation and Pain Modulation in Small Fiber Neuropathy/Fibromyalgia
The investigators will treat patients (targeting enrollment of n=20) who suffer from trigeminal or glossopharyngeal nerve pain in the context of painful small fiber neuropathy.
- Trial name
- NCT04158752
- Testing
- Galcanezumab
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Duke University
Trigeminal Neuralgia
An Efficacy and Safety Study of Basimglurant (NOE-101) in Patients With Trigeminal Neuralgia.
Trigeminal neuralgia (TN), also called "tic douloureux", is the most common form of craniofacial neuropathic pain and is considered the cause of one of the most painful afflictions known in medical practice.
- Trial name
- NCT05217628
- Testing
- Basimglurant
- Where
- 34 sites in United States, Denmark and 6 more
- Volunteers
- 166 people
- Sponsor
- Noema Pharma AG
Trigeminal Neuralgia
OnabotulinumtoxinA for Trigeminal Neuralgia
A randomized controlled trial comparing Onabotulinumtoxin A to saline (placebo) for Trigeminal Neuralgia.
- Trial name
- NCT06216886
- Testing
- OnabotulinumtoxinA 100 UNT [Botox], Sodium Chloride 0.9% for Injection, Preservative Free
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Stanford University
Trigeminal Neuralgia
Resting-State fMRI Study of Functional Connectivity After Gamma Knife Radiosurgery in Trigeminal Neuralgia
Trigeminal neuralgia is a severe chronic pain condition with a major impact on quality of life. Although Gamma Knife radiosurgery is an established treatment for pharmacoresistant trigeminal neuralgia, its mechanisms of action…
- Trial name
- DOCTRINE (NCT07357025)
- Testing
- Resting-State Functional MRI
- Volunteers
- 28 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Trigeminal Neuralgia, Temporomandibular Disorder
Comorbid Painful TMD Among Trigeminal Neuralgia
An observational study following up with trigeminal neuralgia patients to understand their comorbid facial pain condition, specifically temporomandibular disorder.
- Conditions
- Trigeminal Neuralgia, Temporomandibular Disorder, Myofascial Pain, Trigeminal Neuropathy
- Trial name
- TNTMD (NCT05914558)
- Testing
- Clinical appointment
- Where
- 2 sites in United States
- Sponsor
- University of Minnesota
Trigeminal Neuralgia
Efficacy and Safety of Irregular Pulsed Radiofrequency (Sluijter-Teixera Poisson) Versus Regular Pulsed Radiofrequency to the Gasserian Ganglion for Treatment of Primary Trigeminal Neuralgia
This study aims to compare between the Efficacy and safety of irregular pulsed radiofrequency STP versus regular pulsed radiofrequency to the gasserian ganglion for treatment of primary trigeminal neuralgia.
- Trial name
- NCT07275229
- Testing
- Irregular pulsed Radiofrequency, Regular pulsed Radiofrequency
- Volunteers
- 62 people
- Sponsor
- Sohag University
Trigeminal Neuralgia, Neuropathic Pain
Nucleo CMP and Neurorubine Versus Carbamazepine for Classical Trigeminal Neuralgia
Trigeminal neuralgia is a severe facial pain condition that significantly impacts quality of life. While the standard medication, carbamazepine, provides relief, it is often associated with side effects and rapid pain recurrence…
- Trial name
- NCT07304453
- Testing
- Conventional Carbamazepine Therapy, Nucleo CMP and Neurorubine Combination
- Where
- Iraq
- Volunteers
- 38 people
- Sponsor
- Karbala University
Trigeminal Neuralgia, Rhizotomy
Trigeminal Evoked Responses to Improve Rhizotomy
Trigeminal neuralgia (TGN) is a debilitating pain syndrome where electrical, shock- like jolts of pain affect the face. Trigeminal somatosensory evoked potentials (TSEPs) provide a promising modality for measuring the trigeminal…
- Trial name
- NCT05738096
- Testing
- TSEP + rhizotomy surgery, TSEPs recording only
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Trigeminal Neuralgia
Comparison b/w Carbamazepine vs Oxcarbazepine in Treatment of Trigeminal Neuralgia
In this Study investigator is comparing the effectiveness and outcomes of two drugs used un the treatment of trigeminal neuralgia , Carbamazepine vs Oxcarbazepine
- Trial name
- NCT07252453
- Testing
- Carbamazepine, oxcarbazepine
- Where
- Pakistan
- Volunteers
- 122 people
- Sponsor
- Abbasi Shaheed Hospital
Trigeminal Neuralgia
Risk Factors for Recurrence of Trigeminal Neuralgia After Percutaneous Balloon Compression
The goal of this observational study is to develop and validate a machine learning-based model for predicting pain recurrence risk after percutaneous balloon compression (PBC) in adult patients with primary trigeminal neuralgia…
- Trial name
- NCT07238244
- Testing
- Percutaneous Balloon Compression
- Volunteers
- 700 people
- Sponsor
- Second Xiangya Hospital of Central South University
Trigeminal Neuralgia
Trigeminal Neuralgia Electrophysiology
The study intervention is to perform standard somatosensory evoked responses limited to the face during rhizotomy procedures of the gasserian ganglion (trigeminal ganglion) for the treatment of trigeminal neuralgia.
- Trial name
- NCT05269472
- Testing
- Trigeminal Electrophysiology
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Trigeminal Neuralgia
RAD 1501: A Trial of Virtual Cone Trigeminal Neuralgia Radiosurgery
To determine the feasibility of frameless Virtual Cone trigeminal neuralgia radiosurgery at a single institution prior to multi-institutional enrollment.
- Trial name
- NCT02708810
- Testing
- Unframed Virtual Cone, 80 Gy Radiation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Alabama at Birmingham
Trigeminal Neuralgia, Microvascular Decompression Surgery
Post-Operative Trigeminal Pain After Microvascular Decompression for Trigeminal Neuralgia
The goal of this observational study is to learn about the long-term effects of microvascular decompression (MVD) in patients with trigeminal neuralgia (TN).
- Conditions
- Trigeminal Neuralgia, Microvascular Decompression Surgery, Post-operative Pain
- Trial name
- NCT07216547
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Rutgers, The State University of New Jersey
Trigeminal Neuralgia, Tic Douloureux
Prospective Register Study to Assess Eligibility for and Efficacy of Surgical Treatment in Patients With nEuRovascular Conflict
The aim of the registry is a multicenter, prospective long-term data collection of patients suspected neurovascular conflict and referred for possible microvascular decompression (Jannetta procedure).
- Conditions
- Trigeminal Neuralgia, Tic Douloureux, Facial Pain, Glossopharyngeal Neuralgia
- Trial name
- PETER registry (NCT07135024)
- Where
- 2 sites in Germany, Switzerland
- Volunteers
- 5,001 people
- Sponsor
- Gerrit A Schubert
Postherpetic Neuralgia, Peripheral Neuropathic Pain
Clinical Trial of the Safety and Efficacy of Peripheral Nerve Stimulation in the Treatment of Peripheral Neuropathic Pain.
The goal of this clinical trial is to evaluate safety and efficacy of percutaneous peripheral nerve stimulation in patients with peripheral neuropathic pain. The main questions it aims to answer are: 1.
- Conditions
- Postherpetic Neuralgia, Peripheral Neuropathic Pain, Trigeminal Neuralgia
- Trial name
- NCT06290661
- Testing
- Active electrostimulation
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Trigeminal Neuralgia
The Synergism and Attenuation Effects of Electroacupuncture in the Treatment of Trigeminal Neuralgia
Trigeminal neuralgia (TN), characterized by its refractory nature and recurrence, frequently leads to anxiety, depression, and insomnia, thereby significantly diminishing patients' quality of life and potentially inducing…
- Trial name
- NCT07074561
- Testing
- CBZ, Electroacupuncture
- Volunteers
- 28 people
- Sponsor
- Yuanyuan Wu