Clinical trials: Tremor
Essential Tremor, Parkinson's Disease (PD)
Closed-loop TMS for Tremor
This study investigates the potential of phase-locked transcranial magnetic stimulation (TMS) as a non-invasive intervention for tremor in patients with Essential Tremor (ET) and Parkinson's Disease (PD).
- Trial name
- NCT07574164
- Testing
- TMS
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- University of Oxford
Essential Tremor
Essential Tremor in Children and Adolescent
Essential tremor (TE) is the most common abnormal movement of the adult. His diagnosis is based on a bundle of clinical arguments (Movement Disorders Society, 1998).
- Trial name
- NCT03487705
- Testing
- electromyographic essential tremor
- Where
- France
- Volunteers
- 18 people
- Sponsor
- University Hospital, Montpellier
Tremor
Electrophysiological Study of the Effects of Limb Cooling on Essential Tremor
To determine the effects of upper limb forearm cooling on Essential Tremor upper limb tremor using a more practical method of limb cooling through a forearm cold pack.
- Trial name
- NCT01093027
- Testing
- 15 - 30, 30 - 15
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Ataxia, Cerebrovascular Accident
PET Scan to Study Brain Control of Human Movement
Positron Emission Tomography (PET) is a technique used to investigate activity in areas of the brain. The PET technique allows researchers to study the normal processes in the brain (central nervous system) of normal individuals…
- Conditions
- Ataxia, Cerebrovascular Accident, Healthy, Movement Disorder
- Trial name
- NCT00001324
- Where
- United States
- Volunteers
- 510 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Alcohol Withdrawal Syndrome
Treatment of Alcohol Withdrawal Syndrome With Alpha-2 Agonists and/or Anticonvulsants
Complicated alcohol withdrawal syndrome (AWS) increases morbidity and mortality of hospitalized, medically ill patients. The Psychosomatic Medicine Service is commonly consulted to assist in the management of these patients when…
- Trial name
- NCT05438641
- Testing
- BZDP-Sparing Protocol, BZDP-Based Protocol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Stanford University
Kidney Transplant; Complications, Toxicity
Effect of Tacrolimus Formulation on Neurological Side Effects in Older Kidney Transplant Recipients
Previous studies have shown that elderly patients experience higher trough levels of tacrolimus and are more sensitive to the effects of medications, they experience higher occurrence and severity of such medication related…
- Conditions
- Kidney Transplant; Complications, Toxicity, Drug Toxicity, Neurotoxicity
- Trial name
- NCT03461445
- Testing
- Envarsus, IR Tacrolimus
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- University of California, Davis
Essential Tremor
Boston Scientific Registry of Deep Brain Stimulation for Treatment of Essential Tremor (ET)
To compile characteristics of real-world outcomes for Boston Scientific Corporation's commercially approved Deep Brain Stimulation (DBS) Systems, when used according to the applicable Directions for Use, for the treatment of…
- Trial name
- NCT04032470
- Testing
- Deep Brain Stimulation Systems (DBS)
- Where
- 20 sites in Austria, Belgium and 7 more
- Volunteers
- 500 people
- Sponsor
- Boston Scientific Corporation
Essential Tremor, Parkinson Disease
Physiology, Imaging and Modeling of Essential Tremor
This project aims to investigate novel ways to deliver brain stimulation to Essential Tremor (ET) patients by introducing software changes to their existing devices.
- Conditions
- Essential Tremor, Parkinson Disease, Dystonia
- Trial name
- NCT03811405
- Testing
- Active biphasic pulse stimulation---Home Settings, Active biphasic pulse stimulation---VIN Biphasic, Active biphasic pulse stimulation---Stimulator Off
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Florida
Essential Head Tremor
Evaluation of Botulinum Toxin Injection Efficacy in the Treatment of Head Essential Tremor
Essential head tremor (HT) does not usually respond to drug treatment such as propranolol or primidone or to surgical treatment such as deep brain stimulation of the thalamic ventralis intermedius nucleus.
- Trial name
- Btx-HT (NCT02555982)
- Testing
- BOTOX ® 200 Unités
- Where
- 17 sites in France
- Volunteers
- 120 people
- Sponsor
- University Hospital, Clermont-Ferrand
Parkinsons Disease (PD)
Directional PSA Versus STN DBS for TD-PD
The aim of this study is to compare the effectiveness of the deep brain stimulation in the posterior subthalamic area (PSA) versus the subthalamic nucleus (STN) using directional lead for the treatment of tremor-dominant…
- Trial name
- NCT07700862
- Testing
- directional Deep brain stimulation
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Ruijin Hospital
Essential Tremor, Dystonic Tremor
VIM DBS Respiratory Modulation: N-of-1 Trial
Research from our group has demonstrated modulation of PEFR in patients with STN and PAG stimulation. However, the effect of VIM (motor thalamus) stimulation remains to be investigated.
- Trial name
- NCT05381688
- Testing
- VIM DBS
- Sponsor
- University of Oxford
Muscle Damage, Inflammation
Compared Effect of a Fruit Milk Shake With a Protein-Carbohydrate Supplement on Recovery After Resistance Exercise
The aim of this study is to assess the effect of ingesting a commercial carbohydrate and protein dietary supplement in powder form (P-CHO supplement) or a milk shake with skimmed milk, strawberries and banana (MS), after…
- Conditions
- Muscle Damage, Inflammation, Oxidative Stress, Functional Recovery
- Trial name
- NCT01555775
- Testing
- P-CHO supplement, Fruit Milk Shake
- Where
- Portugal
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Universidade do Porto
Parkinson's Disease, Movement Disorders
Effects of Targeted Temporal Interference Stimulation of Cerebellar Nuclei on Tremor and Gait Disturbance in Parkinson's Disease Patients
The goal of this clinical trial is to explore the effects of cerebellar nuclei TIS stimulation on improving tremor and gait disorders in PD patients.
- Trial name
- NCT07384442
- Testing
- Real Temporal Interference Stimulation
- Where
- China
- Volunteers
- 50 people
- Sponsor
- YangPan
Essential Tremor, Upper Extremity Essential Tremor
Coordinated Reset Deep Brain Stimulation for Essential Tremor
Deep brain stimulation (DBS) is a surgical procedure for the treatment of Essential Tremor (ET). A novel approach to current DBS approaches is called coordinated reset DBS (CR-DBS) which uses different patterns of stimulation at…
- Trial name
- NCT05897775
- Testing
- Deep brain stimulation
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Minnesota
Essential Tremor
A Study to Evaluate the Long-term Safety and Tolerability of SAGE-324 in Participants With Essential Tremor
The primary purpose of this study is to evaluate the long-term safety and tolerability of SAGE-324 in participants with essential tremor (ET).
- Trial name
- NCT05366751
- Testing
- SAGE-324
- Where
- 38 sites in United States
- Volunteers
- 97 people
- Sponsor
- Sage Therapeutics
Essential Tremor
Proof of Concept Study on BP1.4979 Effect on Essential Tremor
The goal of this clinical trial is to learn if drug BP1.4979 works to treat essential tremors in adults. It will also learn about the safety of drug BP1.4979.
- Trial name
- NCT07074002
- Testing
- BP1.4979
- Where
- 14 sites in France
- Volunteers
- 50 people
- Sponsor
- Bioprojet
Tremor, Essential Tremor
Deep Brain Stimulation of the Deep Cerebellar Nuclei for Refractory Tremor
This objective of this study is to document the safety and feasibility of electrical stimulation of the deep cerebellar nuclei for refractory tremor using the Medtronic Percept RC Deep Brain Stimulation System.
- Trial name
- rT DBS (NCT07049003)
- Testing
- Deep Brain Stimulation
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- The Cleveland Clinic
Essential Tremor, Cervical Dystonia
Neurophysiologic Study of Patient With Essential Tremor and Dystonic Tremor
Background: Essential tremor is when a person has tremor, but no other neurological symptoms. Dystonic tremor is when a person also has dystonia. Dystonia is a condition in which muscle contraction causes changes in posture.
- Conditions
- Essential Tremor, Cervical Dystonia, Focal Dystonia
- Trial name
- NCT03041714
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Tremor
Investigating Cerebellar Inhibition and Its Clinical Significance in Parkinsonian Tremor and Intention Tremor
Cerebellocerebral connection plays an important function in motor control. Nowadays it can be investigated with neuroimaging and physiological methods in humans.
- Trial name
- NCT05512299
- Testing
- Transcranial Magnetic Stimulation
- Where
- Taiwan
- Volunteers
- 84 people
- Sponsor
- China Medical University Hospital
Tremor, Involuntary Movements
Hyperkinetic Movements in Patients With Disease of Motor Neurons and Their Response to Treatment With Nusinersen
Hyperkinetic movement disorders in patients with diseases of motor neurons will be studied. Patients with spinal muscular atrophy (SMA) and motor neuron disease patients will be studied.
- Conditions
- Tremor, Involuntary Movements, SMA, MND (Motor Neurone DIsease)
- Trial name
- NCT04825119
- Testing
- Nusinersen
- Where
- Slovenia
- Volunteers
- 110 people
- Sponsor
- University Medical Centre Ljubljana