Clinical trials: Trauma Wounds
Partial-thickness Burn Wounds
Evaluating Whether Intact Fish Skin Graft Can Decrease the Need for Autograft in the Treatment of Deep Partial-Thickness Burns
The goal of this randomized controlled clinical trial is to determine whether use of Kericis Intact Fish Skin Graft (IFSG) can decrease the amount of autograft tissue needed for treatment of deep partial-thickness burns in…
- Trial name
- LOGI (NCT07326657)
- Testing
- Intact fish skin graft, autograft
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Kerecis Ltd.
Chronic Pain
Targin® for Chronic Pain Management in Patients With Spinal Cord Injury
The study will be investigating the effectiveness of oxycodone-naloxone (brand name Targin®) at treating chronic pain in individuals with spinal cord injury.
- Trial name
- NCT03179475
- Testing
- Oxycodone Naloxone Combination
- Where
- Canada
- Volunteers
- 1 people
- Sponsor
- University of British Columbia
Chronic Diabetic Foot Ulcers
Pilot Study on Auricular Vagus Nerve Stimulation Effects in Chronic Diabetic Wounds
The purpose of this pilot study is to evaluate the effect of auricular autonomous nervous system stimulation on vital parameters of wound healing in diabetics.
- Trial name
- NCT02098447
- Testing
- PrimeStim
- Where
- Austria
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Fractured Tooth, Decayed Tooth
TetricCAD Crown Clinical Study
This investigation will be a clinical trial to study the performance of a new resin-based ceramic material for crowns. The material has been approved by the FDA for patient treatment.
- Conditions
- Fractured Tooth, Decayed Tooth, Unsatisfactory Restoration of Tooth
- Trial name
- NCT03716817
- Testing
- Tetric CAD
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- University of Michigan
CTS, Carpal Tunnel Syndrome (CTS)
Comparative Efficacy of Neuromobilization, Tendon Gliding Exercises, and Combined Techniques in Mild to Moderate Carpal Tunnel Syndrome
focuses on the comparative efficacy of Neuromobilization techniques, tendon gliding exercises, and their combined application in the management of mild to moderate Carpal Tunnel Syndrome through a randomized controlled trial (RCT)
- Trial name
- NCT07653789
- Testing
- Combined Intervention Group, Neuromobilization Group, Tendon Gliding Exercise Group
- Where
- Pakistan
- Volunteers
- 52 people
- Sponsor
- Ibadat International University, Islamabad
Traumatic Brain Injury
Remifentanil for Sedation of Patients With Traumatic Brain Injury (TBI)
This is a descriptive retrospective study designed to measure the efficacy of remifentanil sedation and the ability to perform frequent neurological examinations of patients with traumatic brain injuries.
- Trial name
- NCT02049320
- Testing
- Remifentanil
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Joseph D. Tobias
Chronic Pain, Trauma
Brief Intervention for Chronic Pain and History of Stressful Experiences
The goal of this study is to understand whether a brief, three session program can be helpful in reducing symptoms related to both chronic pain and stressful experiences/trauma.
- Conditions
- Chronic Pain, Trauma, Adverse Childhood Experiences
- Trial name
- NCT06983327
- Testing
- Trauma Focused Emotional Awareness and Expression Therapy (EAET)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Brigham and Women's Hospital
ACL Injury
Neuromuscular Intervention Targeted to Mechanisms of ACL Load in Female Athletes
Females who participate in cutting and landing sports suffer anterior cruciate ligament (ACL) injuries at a 2 to 10-fold greater rate than males participating in the same high-risk sports.
- Trial name
- NCT01034527
- Testing
- Neuromuscular Training
- Where
- United States
- Volunteers
- 593 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Distal Radius Fractures
ORIF Distal Radius Blood Flow Restriction Therapy
Patients commonly experience a significant amount of muscular atrophy following open reduction internal fixation (ORIF) surgery of distal radius fractures, associated with an increased risk of re-injury, and an increase in time…
- Trial name
- ORIF DR BFR (NCT06136286)
- Testing
- Blood Flow Restriction (BFR) Cuff
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- The Methodist Hospital Research Institute
Trauma
Evaluation of the Effectiveness of a Regional Trauma Care System for the Treatment of Patients With Severe Trauma
Severe trauma imposes a heavy burden to society and family because of its high mortality and disability rate. Based on the implementation plan of "one region", "two links", and "three teams", the Trauma Medicine Center of Peking…
- Trial name
- NCT05799170
- Testing
- regional trauma care
- Volunteers
- 3,200 people
- Sponsor
- Peking University People's Hospital
Femoral Neck Fractures
This is a Study to Verify if Periarticular Hip Injection of Corticosteroid After Hip Replacement Reduce the Pain and the Hospitalisation Time
The investigators are going to evaluate if periarticular corticosteroid injection during endoprothesis implantation can lead to any advantage to the patients, namely if it can reduce post-operative pain, lenght and cost of…
- Trial name
- NCT05023369
- Testing
- Dexamethasone is a steroid drug and will be administered as an injectable solution (4mg/ml)
- Where
- Switzerland
- Volunteers
- 110 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Distal Femur Fracture
Carbo-fix Lateral Plate Devices and Standard Plate-Nail Constructs in Distal Femur Fractures
The purpose of this randomized clinical trial is to decrease non-union rates in distal femur fracture fixation. Carbo-fix lateral femur plate and standard intramedullary nail-plate constructs have been shown to have lower…
- Trial name
- NCT07280169
- Testing
- Carbo-fix Lateral Plate Device, Standard Plate-Nail Construct
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Missouri-Columbia
Fractures
Virtual Reality in Reducing Acute Orthopedic Pain
The primary aim of this research is to show that a virtual reality (VR) service line is feasible and can sustain itself with the ability to take care of patients.
- Trial name
- NCT06624969
- Testing
- virtual reality
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Mayo Clinic
Inhalation Injury, Burn Injury
Trial of Nebulized Heparin Versus Placebo for Inhalation Trauma
The purpose of this international multi-center double-blind randomized placebo-controlled trial is to determine the effect of nebulized heparin, compared to placebo, on the number of ventilator-free days at day 28, in burn…
- Trial name
- Hepburn (NCT01773083)
- Testing
- unfractionated heparin
- Where
- 8 sites in Australia, Belgium and 1 more
- Volunteers
- 13 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Hip Fracture, Blood Loss
Prevention of Postoperative Bleeding in Subcapital Femoral Fractures
The main hypothesis of this clinical trial is that the use of intra-articular tranexamic acid and the fibrin glue plus usual hemostasis will reduce at least a 25% the postoperative blood loss with respect to usual hemostasis in…
- Trial name
- TRANEXFER (NCT02150720)
- Testing
- Tranexamic Acid, Fibrin glue, Electrocauterization
- Where
- 6 sites in Spain
- Volunteers
- 161 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Traumatic Brain Injury
Effects of Intranasal Nerve Growth Factor for Traumatic Brain Injury
Traumatic bain injury(TBI) remains a hidden epidemic involving individuals affected predominantly at a young age who in the most severe cases remain with permanent physical,psychological and cognitive deficits.This study will…
- Trial name
- NCT01212679
- Testing
- nerve growth factor, nomral saline
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Jinling Hospital, China
Blow-Out Fractures
Reconstruction of Orbital Floor Blow-out Fractures by Titanium Mesh Versus Autogenous Iliac Graft
Blow-out fractures result from direct blunt impacts to the orbit which causes an immediate rise increase in intra-orbital pressure. Decompression via fracture of the orbital floor then occurs.
- Trial name
- NCT07340879
- Testing
- Titanium mesh, autogenous iliac graft
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Assiut University
Brain Concussion, Knowledge, Attitudes, Practice
Comparing Concussion Education Types
The purpose of this study is to determine if there are differences in knowledge, self-efficacy, and empathy surrounding concussions, as well as intent to report a concussion, after viewing concussion education (CrashCourse and…
- Trial name
- NCT05836662
- Testing
- CrashCourse Concussion Education in Virtual Reality
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Piya Sorcar
Head Injuries, Penetrating, Head Injuries, Closed
Concordance Between Ultra-low Dose (ULD) and Standard Dose CT Scans in the Search for Traumatic Brain Injury
The aim of this research is to evaluate the diagnostic concordance of ultra low-dose and standard dose reconstructed computed tomography acquisitions using the ADMIRE algorithm to search for intracranial lesions - both…
- Trial name
- ULD-CRANE (NCT04939688)
- Testing
- Conventional dose AND ultra low-dose CT scanning in the search for cranial lesions
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Spinal Cord Injury
Evaluation of a Specialized Yoga Program for Persons With Spinal Cord Injury (SCI)
The purpose of this randomized controlled study is to evaluate psychological variables, mindfulness, and pain in the context of a specialized yoga program for individuals with SCI.
- Trial name
- SCI (NCT02656927)
- Testing
- Yoga Condition
- Volunteers
- 22 people
- Sponsor
- University Health Network, Toronto