Clinical trials: Trauma Patients
Surgical Site Infection
PICO Dressings for Emergency Laparotomy
SSI (Surgical Site Infection) rate is an important consideration after emergency laparotomy. SSIs carry a high financial burden for health institutes with the cost of major SSIs after emergency laparotomy to add an additional…
- Trial name
- NCT05090462
- Testing
- PICO dressing
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- North Middlesex University Hospital NHS Trust
Carpal Tunnel Syndrome
Platelet Rich Plasma and Perineural Injection Therapy for Carpal Tunnel Syndrome
Carpal tunnel syndrome (CTS) is the most common peripheral entrapment neuropathy with involving compression of the median nerve in the carpal tunnel.
- Trial name
- NCT02696161
- Testing
- platelet rich plasma, 5% dextrose
- Where
- Taiwan
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Tri-Service General Hospital (TSGH)
Postoperative Pain
Factors Influencing Postoperative Pain After Gingival Graft Harvesting
This prospective cohort study aims to evaluate patient-related, psychological, and clinical factors influencing postoperative pain following gingival graft harvesting from the palate.
- Trial name
- NCT07377370
- Testing
- Gingival graft harvesting from the palate
- Where
- Spain
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Diabetes Mellitus, Gingival Recession, Generalized
Palatal Wound Healing After Free Gingival Graft Harvest in Diabetic Patients: A Clinical Trial
The goal of this clinical trial is to evaluate local and systemic factors involved in palatal mucosal healing after Free Gingival Graft harvest in diabetic patients and to compare them with those in non-diabetic patients.
- Conditions
- Diabetes Mellitus, Gingival Recession, Generalized, Gingival Recession, Localized
- Trial name
- NCT07500935
- Testing
- Free gingival graft
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Mauro Santamaria
Cesarean Section, Wound Complications
Cesarean Trial of Staples vs. Sutures
To determine whether the rate of wound complications differs based on method of closure of skin incision (staples vs. suture) after cesarean delivery.
- Conditions
- Cesarean Section, Wound Complications, Patient Satisfaction, Pain Measurement
- Trial name
- CROSS (NCT01211600)
- Testing
- Staples, Suture
- Where
- 2 sites in United States
- Volunteers
- 746 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Spinal Cord Injuries
The Enteric Nervous System in Spinal Cord Injury: Study of the Enteric Nervous System and the Intestinal Epithelial Barrier Via Colonic Biopsies in Spinal Cord Injury Patients
The goal of this clinical trial is to learn more about the enteric nervous system (ENS) and the intestinal epithelial barrier (IEB) in patients with spinal cord injury (SCI).
- Trial name
- TENS-SCI (NCT05954845)
- Testing
- biopsies
- Where
- 2 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Spinal Cord Injuries, Rehabilitation
Study on Rehabilitation Exercise Program for Community-based Spinal Cord Injury Patients
In the case of spinal cord injury, patients have shown a passive attitude towards participating in leisure sports or exercise programs, and there is a lack of suitable guidelines or experience in the local community for coaching…
- Conditions
- Spinal Cord Injuries, Rehabilitation, Exercise Program
- Trial name
- NCT05878145
- Testing
- Structured rehabilitation exercise program
- Where
- South Korea
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Pusan National University Yangsan Hospital
Scar, Skin Scarring
Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
Patients will be randomized either to receive standard daily dressing or hydrocolloid dressing using a randomization generator. After closing the wound with the sutures,the scar will be covered by a hydrocolloid dressing, which…
- Conditions
- Scar, Skin Scarring, Skin Cancer, Wound Heal
- Trial name
- NCT05618912
- Testing
- Hydrocolloid dressing, Petrolatum jelly dressing
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Indiana University
Mild Traumatic Brain Injury
Functional MRI Study of Attention in Normal Controls and Traumatic Brain Injured Patients
The purpose of this study will be to assess the attentional ability of patients with mild to moderate traumatic brain injury (TBI) using the functional Magnetic Resonance Imaging (fMRI) technique.
- Trial name
- NCT00580918
- Testing
- functional magnetic resonance imaging fMRI
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Irvine
Acute Lung Injury
Exploratory Clinical Study of Neutrophil Activation Probe (NAP) for Optical Molecular Imaging in Human Lungs
Seriously ill patients may develop a complication called acute lung injury (ALI), a form of inflammation in which lung tissue is filled by fluid containing white blood cells called neutrophils.
- Trial name
- NAP (NCT01532024)
- Testing
- Microdose of NAP
- Where
- 3 sites in United Kingdom
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Subacromial Impingement Syndrome
Effects of Exercise Trainings on Pain, Function and AHD in Patients With SPS
Abnormal reduction of the AHD has been considered as one of the possible mechanisms in the aetiology of subacromial pain syndrome.
- Trial name
- NCT03494192
- Testing
- Scapula Retraction Exercise Group, Scapula Retraction +Glenohumeral Rotational Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Traumatic Brain Injury
Assessment of Noninvasive Neuromodulation in a Group of Traumatic Brain Injured Patients and Healthy Volunteers
Background: Severe traumatic brain injury, particularly diffuse axonal injury (DAI), often leads to lasting neurological issues.
- Trial name
- NCT07373366
- Testing
- Subjects in the intervention group receive low-frequency radioelectric therapy
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Operative Incision
Effect of Intraoperative Ankle Nerve Blocks on Postoperative Discharge in Patients Undergoing Orthopaedic Foot Surgery
Postoperative pain is an important clinical issue which negatively affects patient's satisfaction, delays discharge and repeated admission after discharge in orthopedic surgery.
- Trial name
- NCT03550677
- Testing
- general anesthesia, ankle block
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Diskapi Teaching and Research Hospital
Extraction Socket Healing
Assessment of Topical Application of Chitosan 0.2% Chlorhexidine Gel on Wound Healing in Diabetic Patients
Despite efforts to prevent postoperative discomfort, immediate side effects of surgical extraction of lower molars include bleeding at the site of extraction, inflammation, pain, and alveolar osteitis especially in diabetic…
- Trial name
- NCT07429812
- Testing
- Surgical extraction of the offending tooth will be performed under local anesthesia using inferior alveolar nerve block technique with buccal mucosa infiltration, make an incision on the gingival tis
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Tanta University
Complex Regional Pain Syndrome, Carpal Tunnel Syndrome
Examination of the Pathophysiologic Mechanisms of CRPS by Using QST, CPM, RIC, and Heart Rate Variability QST
This study aims for a better understanding of the pathophysiological mechanisms of the complex regional pain syndrome (CRPS). This will be done by testing the quantitative sensory testing, the remote ischemic conditioning, the…
- Conditions
- Complex Regional Pain Syndrome, Carpal Tunnel Syndrome, Neuralgia
- Trial name
- NCT02261012
- Where
- Germany
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ruhr University of Bochum
Intubation, Cardiac Arrest
ETI During Spinal Trauma
The aim of this study was to compare time, success rates of different tracheal tubes (standard tube and ETView VivaSight SL) for intubation with an immobilized cervical spine in a standardized manikin model.
- Trial name
- NCT02295631
- Testing
- Standard tracheal tube, ETView VivaSight SL
- Where
- Poland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- International Institute of Rescue Research and Education
Postoperative Wound Complications
Negative Pressure Wound Therapy in Cesarean Section
The investigators propose a prospective, randomized trial evaluating the use of negative pressure wound therapy (NPWT) with high risk obstetrical patients.
- Trial name
- NPWTCS (NCT02289157)
- Testing
- Negative pressure wound therapy
- Where
- United States
- Volunteers
- 441 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Craniocerebral Trauma, Traumatic Brain Injury
Effect of Passive Gait Training on the Cortical Activity in Patients With Severe Traumatic Brain Injury.
The aim of this study is to determine whether passive gait training increases arousal, demonstrated as changes in EEG (electroencephalogram) activity.
- Conditions
- Craniocerebral Trauma, Traumatic Brain Injury, "Rehabilitation"
- Trial name
- NCT00430703
- Testing
- body weight support treadmill training
- Where
- Denmark
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Brain Concussion
The s100β Levels in Patients With Mild Brain Injury.
Mild traumatic brain injury (TBI) accounts for the majority of TBI. At present, whether TBI has traumatic intracranial lession is mainly diagnosed by computed tomography (CT), while only 5% of mild TBI has positive CT results.
- Trial name
- NCT06131242
- Testing
- It is an observational study
- Volunteers
- 494 people, healthy volunteers welcome
- Sponsor
- Sumei Lu
Critical Illness, Cardiac Arrest
Swecrit Biobank - Blood Samples From Critically Ill Patients and Healthy Controls
Blood samples are collected and stored in a biobank for later analysis of circulating substances in peripheral blood and genetic variations in patients with severe critical illness and risk of death.
- Conditions
- Critical Illness, Cardiac Arrest, Sepsis, Influenza
- Trial name
- SWECRIT (NCT04974775)
- Testing
- Blood collection, Blood collection, serial sampling
- Where
- 4 sites in Sweden
- Volunteers
- 8,500 people, healthy volunteers welcome
- Sponsor
- Skane University Hospital