Clinical trials: Trauma Centers
Neurogenic Overactive Bladder, Urinary Incontinence
Efficacy Study of Pudendal Neuromodulation for the Treatment of Neurogenic Overactive Bladder
The study is designed to demonstrate that treatment with low level stimulation of the bladder muscles reduces symptoms of urinary incontinence in comparison with no stimulation.
- Conditions
- Neurogenic Overactive Bladder, Urinary Incontinence, Detrusor Overactivity
- Trial name
- ACCEPTANCE (NCT01023269)
- Testing
- InterStim Therapy
- Where
- 8 sites in Belgium, France and 4 more
- Volunteers
- 17 people
- Sponsor
- MedtronicNeuro
Brain Edema, Craniocerebral Trauma
A Comparison Between Two Techniques for Performing Decompressive Craniectomy
The purpose of this study is to compare two surgical techniques for a neurosurgical procedure used to treat cerebral edema (decompressive craniectomy): with watertight duraplasty vs.
- Conditions
- Brain Edema, Craniocerebral Trauma, Infarction, Middle Cerebral Artery
- Trial name
- NCT02594137
- Testing
- Without watertight duraplasty
- Volunteers
- 58 people
- Sponsor
- Hospital of the Restoration, Recife
Trauma (Including Fractures), Trauma Abdomen
5 Minute 'HOT' Trauma CT Rates Of Detection Study
Many injured patients receive urgent CT imaging to identify major injury. CT imaging of trauma patients is often time critical and the accurate detection of life-threatening findings on this CT is essential.
- Conditions
- Trauma (Including Fractures), Trauma Abdomen, Trauma Blunt, Trauma Centers
- Trial name
- NCT07314437
- Testing
- Education
- Where
- United Kingdom
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- University Hospital Plymouth NHS Trust
Spine Fracture, Osteoporosis
Controlled Reduction of AO Spine B3 Fractures in Ankylosing Spinal Disorders Using an Inflatable Positioning Device: Technical Note and Retrospective Single-centre Case Series
Retrospective observational
- Conditions
- Spine Fracture, Osteoporosis, Spondylitis, Ankylosing
- Trial name
- NCT07847320
- Volunteers
- 23 people
- Sponsor
- Diakonie-Klinikum Stuttgart
Spinal Cord Injuries
Self-Management Across the Care Continuum
Persons with spinal cord injury (SCI) face many challenges as they transition from inpatient care to outpatients and on into the community.
- Trial name
- NCT04540679
- Testing
- VIP4SCI
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE)
Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)
This international study, organized by Healing Hope International, is an observational registry designed to collect real-world data on participants living with chronic hypoxic ischemic encephalopathy (HIE) who receive an emerging…
- Conditions
- Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE), Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest, Hypoxic Ischemic Encephalopathy of Newborn
- Trial name
- GEN-HOPE (NCT07264166)
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Healing Hope International
Scapular Fracture
Operative Management of Scapular Fractures
Assessment of functional outcome of operative management of scapular fractures through Arabic version DASH score
- Trial name
- NCT05982327
- Testing
- ORIF
- Volunteers
- 20 people
- Sponsor
- Assiut University
Disorder of Consciousness, Consciousness, Loss of
SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury
Early prediction of outcomes after acute brain injury (ABI) remains a major unsolved problem. Presently, physicians make predictions using clinical examination, traditional scoring systems, and statistical models.
- Conditions
- Disorder of Consciousness, Consciousness, Loss of, Trauma, Brain, Traumatic Brain Injury
- Trial name
- NCT06083441
- Testing
- SeeMe, Coma Recovery Scale-Revised (CRS-R)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Quality Improvement, Informed Consent
Quality Improvement Study on Operative Consent Forms
A Quality Improvement Project was undertaken to improve the completion of operative consent forms within a UK hospital plastic surgery department.
- Trial name
- NCT04493866
- Testing
- Messages to departmental employees to improve quality of consent form completion
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Barts & The London NHS Trust
Spinal Cord Injuries, Neurogenic Bladder
Below the Belt: Non-invasive Neuromodulation to Treat Bladder, Bowel, and Sexual Dysfunction Following Spinal Cord Injury
Recent findings have demonstrated that electrical stimulation to the spinal cord (i.e. implanted electrodes) can significantly recover bladder, bowel, and sexual function after injury.
- Conditions
- Spinal Cord Injuries, Neurogenic Bladder, Neurogenic Bowel, Spinal Cord Stimulation
- Trial name
- NCT04604951
- Testing
- Transcutaneous Spinal Cord Stimulation
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- University of British Columbia
Spinal Cord Injuries
VO2peak and Exercise Efficiency in Upper-body Poling
This study compares peak oxygen uptake (VO2peak) and exercise efficiency in upper-body poling versus arm crank ergometry in trained able-bodied and paraplegic participants.
- Trial name
- NCT03284086
- Testing
- upper-body double-poling, arm crank ergometry
- Where
- Norway
- Volunteers
- 18 people
- Sponsor
- Norwegian University of Science and Technology
Traumatic Brain Injury
Effects of Exercise on Memory in Healthy and Brain-Injured Individuals
Background: Research has shown that one exercise session may improve a person s ability to recall information they learned before the exercise.
- Trial name
- NCT01939769
- Testing
- Exercise - Low-intensity exercise, Exercise - High-intensity exercise
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Sport Related Concussion
Salivary Biomarkers for Concussion
Concussion (CC) (also called mild head trauma), which accounts for 85% of all head injuries, is very common in professional and amateur athletes.
- Trial name
- SportCo (NCT06149351)
- Testing
- Bio-fluid analysis for the implementation of a diagnostic test for sport related concussion
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sys2Diag
Amputations, Peripheral Nerve Injury
Micro-Electrodes Implanted in a Human Nerve
The main objective of the intervention in the study is devise feasibility using high-count microelectrode arrays implanted into peripheral nerves of patients with limb amputations or peripheral nerve injury.
- Conditions
- Amputations, Peripheral Nerve Injury, Spinal Cord Injury
- Trial name
- NCT02034461
- Testing
- Utah Slanted Electrode Array
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Utah
Spinal Cord Injuries (SCI), Upper Limb Function
FES Arm Cycling on Functional Ability and Strength in People With SCI
The goal of this feasibility study is to determine if Functional Electrical Stimulation (FES) arm cycling can be used to improve arm functional ability and arm strength in people with Spinal Cord Injury (SCI).
- Trial name
- NCT07385456
- Testing
- Functional electrical stimulation (FES) arm cycling
- Where
- United Kingdom
- Volunteers
- 6 people
- Sponsor
- Glasgow Caledonian University
Periacetabular Tumor
A Randomized Controlled Study Evaluating Modified Cup Anteversion Placement in Prevention of Postoperative Dislocation in Patients Undergoing Acetabular Tumor Resection and Reconstruction
The purpose of this clinical study is to investigate whether patients who receive modified anteversion angle (( α-15°)±10°) of the acetabular cup have a lower risk of dislocation within one year after surgery, compared to…
- Trial name
- NCT05593146
- Testing
- modified anteversion angle placement(( α-15°)±10°), conventional anteversion angle placement ( α±10°)
- Where
- China
- Volunteers
- 118 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
COVID-19, Acute Kidney Injury
Kidney Disease After COVID-19
To understand the long-term epidemiology, develop effective risk-prediction and stratification tools, and understand the pathobiology of kidney disease in COVID-19 survivors.
- Conditions
- COVID-19, Acute Kidney Injury, Chronic Kidney Injury
- Trial name
- NCT05328986
- Where
- 5 sites in United States
- Volunteers
- 1,753 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Cardiac Disease
Efficacy and Safety of Sivelestat in Preventing Postoperative Acute Lung Injury or Acute Respiratory Distress Syndrome After Cardiac Surgery
The aim of this study is to assess the effectiveness and safety of sivelestat sodium in preventing acute lung injury and/or acute respiratory distress syndrome (ALI/ARDS) following cardiac surgery, with the objective of providing…
- Trial name
- NCT06276569
- Testing
- Sivelestat
- Where
- China
- Volunteers
- 382 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Spinal Cord Injuries
Transcutaneous Spinal Cord Stimulation and Robotic Therapy
Lumbosacral spinal stimulation activates the neural network involved in the control of locomotion at the spinal level. However, its effects are limited to the production of robust rhythmic patterns of alternating movement, being…
- Trial name
- tscs_Lokomat (NCT05210166)
- Testing
- Active tSCS and Lokomat
- Where
- Spain
- Volunteers
- 27 people
- Sponsor
- University of Castilla-La Mancha
Traumatic Brain Injury
Different Feeding in Traumatic Brain Injury Patients
This was a multicenter randomized controlled study of 98 severe Traumatic Brain Injury patients with tracheostomy. Patients enrolled were divided randomly into the observation group with Intermittent Oro-esophageal Tube Feeding…
- Trial name
- NCT06249022
- Testing
- Rehabilitation therapy, Intermittent Oro-esophageal Tube Feeding, Nasogastric tube feeding
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Zeng Changhao