Clinical trials: Trauma/Injury Problem, open to volunteers
Trauma Injury, Trauma, Multiple
Effectiveness of a Self-management Program After Traumatic Injury
Traumatic injuries, defined as a physical injury with sudden onset, are a leading cause to disability and impaired health. Persons who sustain a traumatic injury often report problems in daily life activities and reduced quality…
- Conditions
- Trauma Injury, Trauma, Multiple, Polytrauma
- Trial name
- SEMPO (NCT06305819)
- Testing
- self-management support program, Control group
- Where
- Norway
- Volunteers
- 220 people
- Sponsor
- Oslo University Hospital
Urologic Diseases, Male Urogenital Diseases
Bioengineered Penile Tissue Constructs for Irreversibly Damaged Penile Corpora
The primary objective of this clinical trial is to evaluate the safety of autologous engineered corpora cavernosa + albuginea constructs for treatment of complex penile deformities.
- Conditions
- Urologic Diseases, Male Urogenital Diseases, Penile Diseases, Corpus Callosum Malformation
- Trial name
- NCT03463239
- Testing
- Autologous tissue engineered corpora
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Wake Forest University Health Sciences
Trauma (Including Fractures), Trauma ICU Patients
Mortality of Trauma in the Intensive Care Unit.
In this study, it was planned to establish the factors associated with severe trauma discharged from the intensive care unit and mortality.
- Conditions
- Trauma (Including Fractures), Trauma ICU Patients, Trauma Injury, Trauma Patients in ICU
- Trial name
- MOTRAM-ICU-COL (NCT07208110)
- Testing
- Exposed to trauma, Not exposed
- Where
- Colombia
- Volunteers
- 500 people
- Sponsor
- Hospital Departamental de Villavicencio
Trauma Injury, Coagulopathy
Predictive Accuracy of PLR and PNR in Detecting ETIC
Observational study to know what is the predictive accuracy of platelet-neutrophil ratio (PNR) and platelet-lymphocyte ratio (PLR) done in patients presenting to ED( emergency department)within 6 hours of trauma; in detecting…
- Trial name
- ETIC (NCT07046858)
- Where
- India
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Jubilee Mission Medical College and Research Institute
Trauma Injury
Bioimpedance for Ortho Trauma
Patients with high-energy extremity trauma will undergo imaging with an EIT device in the Emergency Department, Operating Room, Orthopaedic Clinic, and In-patient hospital rooms.
- Trial name
- NCT06858488
- Testing
- Extremity Surgery
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
SCI - Spinal Cord Injury, Upper Extremity Dysfunction
The Utilization Effects of Powered Wearable Orthotics in Improving Upper Extremity Function and ADL in Persons With SCI
To evaluate the usefulness of an upper extremity assistive device, called (MyoPro) in improving upper extremity activities in people with incomplete spinal cord injury. The Department of Defense is supporting this study.
- Conditions
- SCI - Spinal Cord Injury, Upper Extremity Dysfunction, Upper Extremity Problem
- Trial name
- NCT06349434
- Testing
- MyoMo, conventional therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Kessler Foundation
PTSD, Alcohol; Use, Problem
Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma
The U.S. Deaf community - a group of more than one million Americans who communicate using American Sign Language (ASL) - experiences nearly triple the rate of lifetime problem drinking and twice the rate of trauma exposure…
- Trial name
- NCT06278922
- Testing
- Seeking Safety + Signs of Safety toolkit, Treatment as usual
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Massachusetts, Worcester
Trauma Injury, Modified Trauma Scoring Systems
FOUR Score-Modified Trauma Scores for Mortality Prediction
The goal of this multicenter prospective observational cohort study is to develop and validate FOUR Score-modified trauma scoring systems for mortality prediction in adult trauma patients.
- Conditions
- Trauma Injury, Modified Trauma Scoring Systems, FOUR Score
- Trial name
- FOUR-TRAUMA (NCT07819279)
- Where
- Iraq
- Volunteers
- 2,000 people
- Sponsor
- Al-Nahrain University
Problem Behavior, Aggression
Extensions of Resurgence as Choice
Although behavioral treatments for decreasing destructive behavior, such as differential reinforcement of alternative behavior (DRA), are effective in the clinic, problem behavior often returns when a caregiver does not give the…
- Conditions
- Problem Behavior, Aggression, Self-Injury
- Trial name
- NCT05537610
- Testing
- CDT, Control
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Vascular Injury, Arterial Injury
Multicenter Study to Evaluate the Safety and Efficacy of SYMVESS™ in a Real World Setting in Patients With Extremity Arterial Injury Requiring Urgent Repair
The goal of this post-marketing observational study is to further assess the long-term safety and efficacy of Symvess in a real-world setting in adult patients with extremity arterial injury.
- Conditions
- Vascular Injury, Arterial Injury, Trauma Injury
- Trial name
- NCT07762794
- Testing
- Acellular Tissue Engineered Vessel
- Volunteers
- 125 people
- Sponsor
- Humacyte, Inc.
Injury Traumatic, Survivorship
Human-centered Injury Thrivorship Pathway for Survivors of Physical Trauma
The goal of this clinical trial is to pilot and evaluate a human-centered injury thrivorship pathway in injury survivors. The main question it aims to answer is: Is the pathway appropriate, acceptable, and feasible to meet the…
- Conditions
- Injury Traumatic, Survivorship, Trauma Injury
- Trial name
- NCT06292039
- Testing
- Human-Centered Injury Thrivorship Pathway
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of California, San Francisco
Pelvic Bone Injury, Pelvis Injury
RELIEVED (REgionaL anesthesIa PElVic fracturEs stuDy) Study. Regional Anesthesia (RA) Techniques for Pain Management in Pelvic Fractures: A Prospective, Monocentric, Pilot Cohort Study.
The goal of this observational clinical trial is to assess the impact of Regional Anesthesia (RA) techniques with the strongest anatomical and scientific support in controlling acute post-operative pain in pelvic/acetabular…
- Conditions
- Pelvic Bone Injury, Pelvis Injury, Acetabular Fractures, Acetabular Surgery
- Trial name
- RELIEVED (NCT07072286)
- Testing
- Regional Anesthesia, Multimodal analgesia
- Where
- Italy
- Volunteers
- 177 people
- Sponsor
- A.O.U. Città della Salute e della Scienza
Psychiatric Problem, Child Neglect
Implementing Dyadic Developmental Psychotherapy (DDP) - Evaluation Research
The objective of this study is to evaluate the implementation and use of Dyadic Developmental Psychotherapy (DDP) in three centra, with particular focus on its potential effects on the quality of the observable caregiver-child…
- Conditions
- Psychiatric Problem, Child Neglect, Maltreatment, Child Behavior Problem
- Trial name
- NCT04763720
- Testing
- Dyadic Developmental Psychotherapy
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Sykehuset Telemark
Traumatic Injury
Ketogenic Feeding for Muscle Preservation After Trauma
The purpose of this study is to determine whether a ketogenic diet, provided as tube feeding, compared with a standard hospital tube feeding, is safe and feasible and helps preserve muscle mass and improve metabolic health in…
- Trial name
- KETO TRAUMA (NCT07827820)
- Testing
- Ketogenic feeding, Standard feeding
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Alabama at Birmingham
Trauma Centers, Trauma Patients
Assess the Efficacy of Tailored Patient Information and Voluntary Patient-managed Outpatient Digital Follow-up (I-POD) as an Adjunct to Standard Treatment According to National Guidelines in the National Trauma Plan Among Adult Trauma Patients in Norway.
The POSTRAUMA trial is a clinical trial at The Regional trauma centre of Western Norway, Haukeland University Hospital. Trauma is the leading cause of death worldwide in patients aged 1-45 years.
- Conditions
- Trauma Centers, Trauma Patients, Trauma (Including Fractures), Trauma Injury
- Trial name
- POSTRAUMA (NCT07268716)
- Testing
- The intervention is a tailored patient Information and Patient-managed Outpatient Digital follow-up treatment
- Where
- Norway
- Volunteers
- 256 people
- Sponsor
- Haukeland University Hospital
Autism Spectrum Disorder, Challenging Behaviour
Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism
The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors.
- Conditions
- Autism Spectrum Disorder, Challenging Behaviour, Aggression, Severe Disruptive Behaviour Disorders
- Trial name
- NCT07091279
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Jeremy Veenstra-vanderweele
Executive Function Deficits (EFD), Developmental Coordination Disorder
Let's CO-OPerate! Together we Are Stronger
The goal of this replicated single case experimental study using a randomized multiple baseline design across participants and goals is to enable children/adolescents (aged 8-16 years) with developmental coordination disorders…
- Conditions
- Executive Function Deficits (EFD), Developmental Coordination Disorder, Acquired Brain Injury (Including Stroke), Brain Injury, Fetus and Neonate
- Trial name
- NCT07085403
- Testing
- Cognitive Orientation to daily Occupational Performance (CO-OP) is a cognitive problem-solving approach
- Where
- France
- Volunteers
- 12 people
- Sponsor
- Hopitaux de Saint-Maurice
Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms
Personalizing Treatment Delivery
Anxiety and anxiety-related disorders frequently co-occur with alcohol use problems resulting in an enormous humanitarian and economic cost to society.
- Conditions
- Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms, Alcohol; Use, Problem; Alcohol Use Disorder
- Trial name
- NCT05821634
- Testing
- Personalized intervention condition: Cognitive behavioral therapy skills, Therapeutic control condition: Cognitive behavioral therapy skills, Tracking control condition: Supportive counseling
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Rutgers, The State University of New Jersey
Trauma Injury
Retrospective Assessment of Referral of a Major Trauma Patient
The aim of this study is to find out whether major trauma patients from the Val d'Oise are referred to the appropriate trauma centre for their care and to assess the quality of triage within the Val d'Oise department.
- Trial name
- SAMU-TRAUMAS (NCT06551350)
- Testing
- Data Collection
- Where
- France
- Volunteers
- 461 people
- Sponsor
- Hôpital NOVO
Depression and Quality of Life, Sexual Violence
Empowerment Self Defense Program for Adult Native Women Survivors of Sexual Violence
The purpose of this study is to culturally adapt and evaluate an empowerment self-defense (ESD) program (i.e., IMpower) for AI/AN women who have experienced SV in their lifetime and currently experiencing moderate to severe…
- Conditions
- Depression and Quality of Life, Sexual Violence, PTSD, Suicidal Ideation
- Trial name
- ESD (NCT07712796)
- Testing
- Empowerment self-defense training
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Michigan