Clinical trials: Trauma/Injury Problem
Trauma Injury, Maxilla Fracture
Prospective Study to Evaluate the Performance and the Safety of Global D's Implants of Craniomaxillofacial Surgery (CMF) Ranges Indicated for Trauma Surgery
This study is set up within the framework of the European Union regulation 2017/745 on medical devices. Its objective is to confirm the performance and safety of the Global D implants (ORTRAUTEK® and MINITEK/MICROTEK®) used for…
- Conditions
- Trauma Injury, Maxilla Fracture, Maxillofacial Trauma
- Trial name
- NCT05742932
- Testing
- Trauma surgery using Global D's implants.
- Where
- 2 sites in France
- Volunteers
- 99 people
- Sponsor
- Global D
Critical Illness, Heart Failure
Self-directed Mobile Mindfulness to Address ICU Survivors' Psychological Distress
Serious acute heart and lung illnesses like heart failure, severe COVID, and sepsis often leave survivors struggling not only physically, but also with lasting depression, anxiety, and stress.
- Conditions
- Critical Illness, Heart Failure, Sepsis, Ards
- Trial name
- Lift 3 (NCT07634419)
- Testing
- Lift mobile mindfulness, Enlighten Recovery education program
- Where
- 3 sites in United States
- Volunteers
- 450 people
- Sponsor
- Duke University
Trauma Injury
Using the GTOS to Stratify the Mortality Risk of Adult Trauma Patients
Trauma significantly impacts both short- and long-term health outcomes, resulting in substantial mortality. Early identification and risk stratification in trauma patients are crucial for timely medical interventions.
- Trial name
- NCT06475612
- Testing
- Death, Survival
- Where
- Taiwan
- Volunteers
- 40,068 people
- Sponsor
- Chang Gung Memorial Hospital
Brain Concussion
Enhanced Problem-Solving Training
Mild traumatic brain injury (mTBI) is among the most common injuries sustained by Veterans of Operations Enduring and Iraqi Freedom.
- Trial name
- E-PST (NCT03759223)
- Testing
- Enhanced Problem-Solving Training (E-PST), Healthy Living Messages (HLM), Enhanced Problem-Solving Training (E-PST) (non-randomized)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- VA Office of Research and Development
Autism Spectrum Disorder, Challenging Behaviour
Propranolol for Aggression, Self-Injury, and Severe Disruptive Behavior in Adolescents and Adults With Autism
The goal of this clinical trial is to learn if propranolol can help reduce challenging behaviors associated with Autism Spectrum Disorder, including aggression, self-injury, and severe disruptive behaviors.
- Conditions
- Autism Spectrum Disorder, Challenging Behaviour, Aggression, Severe Disruptive Behaviour Disorders
- Trial name
- NCT07091279
- Testing
- Propranolol
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Jeremy Veenstra-vanderweele
Emergency Service, Hospital, Child/Adolescent Problem
A RCT of a Combination of Analgesics for Pain Management in Children With a Suspected Fracture
MSK-I is the most common cause for ED visits for children with pain, with a child's risk of sustaining a fracture ranging from 27-42% by the age of 16 years.
- Conditions
- Emergency Service, Hospital, Child/Adolescent Problem, Acute Pain, Fentanyl
- Trial name
- CAST (NCT02985177)
- Testing
- INF2.0 + IBU, INF1.0 + IBU
- Where
- 3 sites in Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Trauma Injury
ICG Fluorescence Imaging in Open Fracture Trauma Patients
This is a prospective observational study that will evaluate the association between bone and tissue perfusion, as measured by indocyanine green (ICG) fluorescence imaging, and complications, in an effort to develop ICG…
- Trial name
- NCT04416412
- Testing
- Immunofluorescence Imaging
- Where
- 4 sites in United States
- Volunteers
- 124 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Trauma Injury, Bone Infection
ICG 24h Prior to Operative Treatment of Orthopaedic Infection
The focus of this study is to (1) Explore variability in distribution of 24h ICG in bone and soft tissue infection (2) Evaluate the change in 24h ICG distribution from pre to post debridement (3) Preliminarily determine whether…
- Trial name
- NCT04927637
- Testing
- imaging 24 hours following intravenous administration of ICG
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Trauma Injury, Old Injury
Epidemiological Characteristics of Elderly Trauma Patients in Zhejiang Province and Development of Geriatric Trauma Short-term Mortality Prediction Model
This is a retrospective study. Trauma patients aged 65 years or older will be included. The aims of this study are explore the epidemiological characteristics of elderly trauma patients in Zhejiang Province; establishment of…
- Trial name
- NCT04954768
- Where
- China
- Volunteers
- 350 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Trauma Injury, Thromboembolism
Antithrombin to Improve Thromboprophylaxis and Reduce the Incidence of Trauma-Related Venous Thromboembolism
The purpose of this study is to determine if additional interventions will assist with decreasing the risk and/or severity of thromboembolism (clotting complications) in patients who have experienced a major traumatic event.
- Conditions
- Trauma Injury, Thromboembolism, Venous Thromboembolism
- Trial name
- TRAIT (NCT05794165)
- Testing
- Thrombate infusion
- Where
- 5 sites in United States
- Volunteers
- 314 people
- Sponsor
- Bryan Cotton
Behavior Problem
Improving Initial Management of the Injured at Ghanaian District and Regional Hospitals With a Trauma Intake Form
Brief Summary: Improving care of the injured (trauma care) is a way to the large burden of injury in low- and middle-income countries. The important initial period of trauma care is often chaotic and prone to errors.
- Trial name
- NCT04547192
- Testing
- Improving initial care of the injured
- Where
- Ghana
- Volunteers
- 4,105 people
- Sponsor
- Kwame Nkrumah University of Science and Technology
Care Partners of Patients With Traumatic Brain Injury (TBI)
Problem Solving Training for Care Partners of Adults With Traumatic Brain Injury
Importance: The chronic consequences of TBI are established, but ongoing support for adults with TBI living in the community is limited.
- Trial name
- CP-PST (NCT03739450)
- Testing
- Problem Solving Training (PST), Education
- Where
- 4 sites in United States
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Balance Disorders, Foot Injury
The Effect of Subtalar Joint Pronation Amount on Lower Extremity Alignment and Performance
The lower extremity consists of segments that can be affected by the relative position of each other. Deviation of one segment from its normal alignment in the lower extremity also affects the alignment of other segments.
- Conditions
- Balance Disorders, Foot Injury, Lower Extremity Problem
- Trial name
- NCT06300671
- Testing
- Foot Posture Index-6
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Trauma Injury
How Many Patients Suffering Major Trauma Would be Eligible for a Pre-hospital Transfusion
The aim of the study is to measure the number of patients being cared for by a medical team for major trauma who could benefit from a transfusion labile blood products and thus provide a scientific argument in favour of supplying…
- Trial name
- TRAP (NCT06494293)
- Testing
- Data Collection
- Where
- 4 sites in France
- Volunteers
- 200 people
- Sponsor
- Hôpital NOVO
Rib Fracture, Rib Fracture Multiple
Orthosis of Acute Traumatic Rib Fractures Via RibFx Belt for Pain Alleviation and Improved Pulmonary Function
Acute traumatic rib fractures are a common issue for patients of trauma surgeons. They inflict substantial morbidity, the most dreaded and consequential of which are pulmonary complications.
- Conditions
- Rib Fracture, Rib Fracture Multiple, Trauma, Trauma Chest
- Trial name
- RibFx (NCT03846024)
- Testing
- RibFx Orthosis Belt
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Vermont Medical Center
Aging, Mental Health Issue
Nordic Walking Training Program for Sustaining Independent Walking in Older Adult Evacuees
Abstract: The purpose of this pilot study is to examine the effect and feasibility of a Nordic walking group training intervention on the physical and mental health of older adults evacuated from their homes to Haifa.
- Conditions
- Aging, Mental Health Issue, War-Related Trauma
- Trial name
- NCT06404216
- Testing
- Nordic walking group training
- Where
- Israel
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Trauma Injury, Intensive Care Neurological Disorder
Experiences and Attitudes Towards Agitated Behaviours in TBI ICU Patients: a Protocol for an Interprofessional Mixed-method Study
EXSTATIC is a multicenter mixed methods convergent study exploring experiences and attitudes of ICU healthcare professionals caring of agitated traumatic brain injury (TBI) patients.
- Trial name
- EXSTATIC (NCT04741399)
- Volunteers
- 98 people
- Sponsor
- Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal
Trauma Injury, Child, Only
Using mHealth to Improve Emotional Recovery After Pediatric Injury
Nearly 300,000 U.S. children experience injuries that require them to be hospitalized this year. These children, and their caregivers, are at high risk for emotional and behavioral problems, as well as poor quality of life.
- Conditions
- Trauma Injury, Child, Only, Posttraumatic Stress Disorder, Parents
- Trial name
- NCT04579198
- Testing
- Caregivers' Aid to Accelerate Recovery after pediatric Emergencies (CAARE)
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Head Trauma, Craniocerebral Injuries
Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas
The goal of this study is to determine the sensitivity, specificity, and positive and negative predictive values of the a portable near-infrared-based device (portable NIR-based device), the InfraScanner 2000™, to detect…
- Conditions
- Head Trauma, Craniocerebral Injuries, Crushing Skull Injury, Head Injuries
- Trial name
- NCT04505293
- Testing
- InfraScanner 2000™
- Where
- 2 sites in United States, Uganda
- Volunteers
- 672 people
- Sponsor
- Duke University
Trauma Injury, Bleeding
Micro Plug Set - Post Market Clinical Follow-up (PMCF) Plan
This is an observational, post market clinical follow-up (PMCF) intended to evaluate the residual risks of the Micro Plug Set which is intended for use during arterial embolization of the peripheral vasculature.
- Trial name
- NCT04218292
- Testing
- Micro Plug Set
- Where
- Germany
- Volunteers
- 40 people
- Sponsor
- KA Medical, LLC