Clinical trials: Trauma, Multiple
Polytrauma, Psychological Distress
Psychological Distress in Relatives of Severely Injured Patients
Patients who have sustained and survived a polytrauma do heavily depend on the support and functioning of their family. This is only possible if the family members are physically and mentally able to cope with the situation.
- Conditions
- Polytrauma, Psychological Distress, Relatives
- Trial name
- NCT03137420
- Testing
- Numeric Scale of Family Distress
- Where
- Switzerland
- Volunteers
- 100 people
- Sponsor
- University of Zurich
Multiple Trauma
A Feasibility Study to Assess Pre Admission Status and Six Month Outcomes After Major Trauma
This study aims to assess the feasibility of obtaining details about a patients previous level of function from the patient of friend/relative, after they have been admitted an intensive care unit (ICU).
- Trial name
- NCT02917694
- Where
- United Kingdom
- Volunteers
- 57 people
- Sponsor
- Oxford University Hospitals NHS Trust
Multiple Trauma, Sepsis
The Role of Post-traumatic Inhibition of the Innate and Adaptive Immune System in the Development of Infectious Complications in Severely Injured Patients
Patients admitted to the Intensive Care Unit after severe injury are prone to suffer from infectious complications and even sepsis.
- Conditions
- Multiple Trauma, Sepsis, Innate Immune Response, Disorder of Neutrophils
- Trial name
- POSEIDON (NCT03489577)
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- UMC Utrecht
Multiple Trauma/Injuries
A Multicenter, Randomized Study of Early Assessment by CT Scanning in Severely Injured Trauma Patients
Computed tomography (CT) scanning has become essential in the early diagnostic phase of trauma care because of its high diagnostic accuracy.
- Trial name
- REACT-2 (NCT01523626)
- Testing
- Total body Computed Tomography., Conventional imaging and selective CT scanning.
- Where
- 5 sites in Netherlands, Switzerland
- Volunteers
- 1,083 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Multiple Trauma
Return to Work After Potential Severe Injury
In Norway an estimated 10 % of the population is injured annually. Of these 36.000 sustain permanent functional impairment, 1.200 receive disability pension, and approximately 2.500 die because of their injuries.
- Trial name
- NCT02602405
- Where
- 8 sites in Norway
- Volunteers
- 1,741 people
- Sponsor
- Norwegian University of Science and Technology
Trauma, Multiple Trauma
Establishment of Regional Severe Trauma Management System
To evaluate the effects of trauma treatment team establishment on the treatment of patients with severe trauma.
- Conditions
- Trauma, Multiple Trauma, Emergencies
- Trial name
- NCT03363880
- Testing
- trauma treatment team, Basic experimental settings
- Volunteers
- 7,250 people
- Sponsor
- Peking University People's Hospital
Burns, Trauma
Microcirculatory Assessment in Patients With Trauma and Severe Burns
Predict the development of multiple organ failure in patients with trauma and severe burns.
- Trial name
- NCT01922960
- Testing
- micro-imaging
- Where
- United States
- Sponsor
- University of South Alabama
Shock, Hemorrhagic, Fractures, Bone
Retroperitoneal Packing or Angioembolization for Hemorrhage Control of Pelvic Fractures
This study is designed to answer whether minimal invasive vessel clotting (angioembolization) or open surgery (retroperitoneal packing) is more effective for pelvic fractures with massive bleeding.
- Conditions
- Shock, Hemorrhagic, Fractures, Bone, Multiple Trauma
- Trial name
- NCT02535624
- Testing
- PACKING, ANGIO
- Where
- China
- Volunteers
- 56 people
- Sponsor
- Uppsala University
Geriatrics
Geriatric Polytrauma SOP
This study investigated whether there were improvements in the in-hospital mortality, infection rate, and rate of palliative care among geriatric trauma patients after the implementation of new standard operating procedures…
- Trial name
- NCT03319381
- Testing
- Following new SOPs
- Volunteers
- 311 people
- Sponsor
- University of Zurich
Acute Pain, Multiple Trauma
Ketamine Patient-Controlled Analgesia for Acute Pain
This study will compare ketamine and hydromorphone as alternative patient-controlled interventions for trauma-related pain. Patients receiving ketamine PCA are expected to require less total and breakthrough opioid and to have…
- Conditions
- Acute Pain, Multiple Trauma, Fractures
- Trial name
- NCT02062879
- Testing
- Ketamine, Hydromorphone
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Traumatic Brain Injury, Trauma
Corticosteroid Therapy for Glucocorticoid Insufficiency Related to Traumatic Brain Injury
Traumatic brained injured (TBI) patients frequently suffered from glucocorticoid insufficiency that is associated with a raise in the rate of pneumonia.
- Conditions
- Traumatic Brain Injury, Trauma, Adrenal Insufficiency, Pneumonia
- Trial name
- Corti-TC (NCT01093261)
- Testing
- Hydrocortisone Fludrocortisone
- Where
- 18 sites in France
- Volunteers
- 336 people
- Sponsor
- Nantes University Hospital
Multiple Organ Failure, Sepsis
Pharmacokinetics of Two Different High-dose Regimens of Intravenous Vitamin C in Critically Ill Patients
The purpose of this study is to determine the pharmacokinetic properties of two different dosage regimens of intravenous vitamin C in patients admitted to the Intensive Care Unit with life-threatening illness.
- Conditions
- Multiple Organ Failure, Sepsis, Systemic Inflammatory Response Syndrome, Trauma
- Trial name
- NCT02455180
- Testing
- Ascorbic Acid
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Amsterdam UMC, location VUmc
Wounds and Injuries, Multiple Trauma
Normal Saline Versus Plasmalyte in Initial Resuscitation of Trauma Patients
The purpose of this study is to determine whether an intravenous salt solution called "Plasmalyte" causes less abnormality of the body's acid levels than a solution called "Normal Saline."
- Conditions
- Wounds and Injuries, Multiple Trauma, Disorder of Fluid Balance
- Trial name
- NCT01270854
- Testing
- Plasmalyte A, Normal Saline
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- University of California, Davis
Distal Radius Fracture, Multiple Trauma
Dynamic External Fixation in Treatment Distal Radius Fractures - Elderly Patients
A single center, parallel group, prospective, randomized clinical trial was conducted at the department of Hand Surgery, ABC (Andre, Bernardo, Caetano) Foundation University Hospital, Santo Andre, Brazil.
- Conditions
- Distal Radius Fracture, Multiple Trauma, Elderly Person Maltreatment
- Trial name
- NCT03154424
- Testing
- External fixation in treatment the distal radius fracture
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Faculdade de Medicina do ABC
Trauma, Multiple, Lactate Blood Increase
Feasibility of Lactate Level Evaluation in Prehospital Care in Trauma
Capillary or venous lactate level evaluation in prehospital care could be simple and beneficial tool for optimising prehospital care in patients with severe trauma.
- Trial name
- NCT03115970
- Testing
- capillary and venous lactate level measurement
- Volunteers
- 30 people
- Sponsor
- Masaryk Hospital Usti nad Labem
Trauma, Multiple
Shock Index To DEtect Low Plasma Fibrinogen In Trauma (SIDE)
Shock-index is potentially an easy tool to estimate the risk of hypofibrinogenemia without the need to perform other potentially time consuming investigations.
- Trial name
- SIDE (NCT02619539)
- Testing
- plasma fibrinogen measurement
- Where
- 2 sites in Czechia
- Volunteers
- 280 people
- Sponsor
- Masaryk Hospital Krajská zdravotní a.s.
Mental Disorders, Multiple Trauma
Microfinance Intervention to Improve Health of Trauma Survivors in DRC
The objective is to test the effectiveness of a village-led microfinance program, Pigs for Peace, on health, household economic stability, and reintegration of trauma survivors to family and community.
- Trial name
- NCT02008708
- Testing
- Livestock Microfinance, Delayed Control Group
- Where
- Republic of the Congo
- Volunteers
- 878 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Clavicle Fracture, Chest Injury
Operative Versus Non-Operative Treatment of Clavicle Fracture in PolyTrauma
About 90% of chest injuries in America are due to blunt forces, mostly as a result of motor vehicle collisions and falls. Severity varies from minor bruising to severe chest injuries.
- Trial name
- NCT01133769
- Where
- United States
- Sponsor
- Anna Rockich
Multiple Trauma
Tissue Perfusion Indices as Predictor of Outcome in Poly Trauma Patients
Early intervention and resuscitation based upon a lot of clinical, laboratory findings make a big difference regarding outcome in poly trauma patients, the study uses the dynamic lactate change and the difference between arterial…
- Trial name
- NCT02727946
- Testing
- optimal resuscitation
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Assiut University
Humeral Fractures, Multiple Trauma
Plating of Humeral Shaft Fractures in Multiple Trauma Patients.
The purpose of this study is to review our experience with the operative management of acute diaphyseal fractures of the humerus via an anterolateral approach with the use of small fragment fixation at a Level I, urban, trauma…
- Trial name
- HUMERUS (NCT00720681)
- Volunteers
- 96 people
- Sponsor
- OhioHealth