Clinical trials: Trauma, Multiple
Exanguination, NCTH
Abdominal Aortic Junction Tourniquet (AAJT-S) for Non-compressible Torso Haemorrhage
This study seeks to evaluate the feasibility of a Abdominal Aortic Balloon Occlusion of the Aorta (AAJT-S) in exanguinating trauma patients with non-compressible truncal haemorrhage in the emergency room and the pre-hospital…
- Conditions
- Exanguination, NCTH, Polytrauma
- Trial name
- NCT06622317
- Where
- Austria
- Volunteers
- 10 people
- Sponsor
- Medical University of Graz
Trauma, Trauma Injury
Whole Blood in Trauma Patients With Hemorrhagic Shock
This study aims to evaluate among trauma patients with hemorrhagic shock the clinical impact of hemostatic resuscitation between whole blood vs.
- Conditions
- Trauma, Trauma Injury, Trauma, Multiple
- Trial name
- WEBSTER (NCT05634109)
- Testing
- Transfusion of blood products
- Where
- Colombia
- Volunteers
- 220 people
- Sponsor
- Fundacion Clinica Valle del Lili
Trauma, Multiple, Trauma
Swiss Trauma Registry
The Swiss Conference of Cantonal Health Directors has transferred the planning of highly specialized medicine to a specialized body under the direction of the Swiss Academy of Sciences.
- Trial name
- NCT03526029
- Where
- 12 sites in Switzerland
- Volunteers
- 2,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Neurologic Disorder, Stroke
Home Based Tele-exercise for People With Chronic Neurological Impairments
To assess the impact of a 12-week virtual seated physical intervention on cardiovascular health and wellness in people with chronic neurological impairments (CNI).
- Conditions
- Neurologic Disorder, Stroke, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- Telex (NCT04564495)
- Testing
- Seated exercise
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Burke Medical Research Institute
Hemorrhage, Shock, Traumatic
The AT-REBOA Target Trial
Temporary aortic occlusion can limit haemorrhage, can help to maintain perfusion to the heart and brain, and may be associated with improved survival.
- Conditions
- Hemorrhage, Shock, Traumatic, Cardiac Arrest Due to Trauma, Polytrauma
- Trial name
- AT-REBOA (NCT06312436)
- Testing
- Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)
- Where
- 2 sites in Austria
- Volunteers
- 44 people
- Sponsor
- Medical University of Graz
SIRS, Sepsis
NT-proBNP in ICU Postoperative/Posttraumatic Patients With Shock
The purpose of this study is to determine the course of NT-proBNP plasma concentrations in the context of confounding parameters in postoperative/posttraumatic critically ill patients with severe SIRS/sepsis and shock.
- Conditions
- SIRS, Sepsis, Shock, Critically Ill
- Trial name
- NICUPS (NCT00736723)
- Where
- Germany
- Volunteers
- 51 people
- Sponsor
- University of Ulm
Flail Chest, Rib Fractures
Mortality Causes in Rib Surgery Patients
This study retrospectively investigates the causes of mortality and morbidity in patients undergoing rib fracture surgery due to blunt trauma.
- Conditions
- Flail Chest, Rib Fractures, Thoracic Injuries, Pulmonary Contusion
- Trial name
- NCT06755723
- Testing
- Rib fractures manangement
- Volunteers
- 112 people
- Sponsor
- Caner İşevi, MD
Pain, Traumatic Brain Injury
The NRC Dataset. Developing a Minimum Dataset for Multidisciplinary Rehabilitation: a Modified E-Delphi Study
Several rehabilitation datasets are presently in use for specific patient groups in England. The 'National Clinical Audit of Specialist Rehabilitation for patients with complex needs following major injury' (NCASRI) evaluated…
- Conditions
- Pain, Traumatic Brain Injury, Major Trauma, Multiple Sclerosis
- Trial name
- NCT06726135
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- ThomasCorbett
Augmented Renal Clearance, Critical Illness
Incidence and Associated Risk Factors of ARC in the Trauma Critically Ill Older Than 50 Years Old
This single-center prospective cohort study conducted at the adult trauma ICU of the Montreal General Hospital (MGH) affiliated with the McGill University Health Centre (MUHC) aims to determine the incidence and associated risk…
- Conditions
- Augmented Renal Clearance, Critical Illness, Polytrauma, Traumatic Brain Injury
- Trial name
- NCT04766944
- Testing
- No intervention
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Trauma, Trauma Blunt
Trauma Registry in Villavicencio, Colombia
Introduction: Injuries are a leading cause of mortality worldwide. It is necessary to know the incidence of injuries, mechanisms of wounds, therapy provided, and outcomes.
- Conditions
- Trauma, Trauma Blunt, Penetrating Wounds, Severe Trauma
- Trial name
- TRaVi (NCT05954936)
- Testing
- Risk factor
- Where
- Colombia
- Volunteers
- 250 people
- Sponsor
- Hospital Departamental de Villavicencio
Polytrauma
Comparing Exponential Injury Severity Score (EISS) With Injury Severity Score (ISS) and New Injury Severity Score (NISS)
Trauma is defined as a physical injury from an external source of sudden onset and severity, which require immediate medical attention.
- Trial name
- NCT06653816
- Where
- Egypt
- Volunteers
- 250 people
- Sponsor
- Assiut University
Pain, Acute, Rib Fractures
Mid-point to Pleura Transverse Process Block Versus Thoracic Intervertebral Foramen Block
The analgesic effect of continuous mid-point to pleura transverse process block compared to the analgesic effect of continuous thoracic intervertebral foramen block, in patients with multiple rib fractures.
- Conditions
- Pain, Acute, Rib Fractures, Polytrauma
- Trial name
- NCT05348330
- Testing
- Thoracic intervertebral foramen block, Mid-point to pleura transverse process block
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- San Salvatore Hospital of L'Aquila
Polytrauma, Traumatic Brain Injury
Age, Traumatic Brain Injury and Injury Severity as Independent Risk Factors for In-Hospital Mortality in Polytrauma Patients.
In this study patients who were admitted to our hospital with critical injuries were enrolled retrospectively from January 2012 to December 2015.
- Trial name
- NCT04335838
- Testing
- retrospective analysis
- Where
- Austria
- Volunteers
- 400 people
- Sponsor
- Medical University of Vienna
Polytrauma
25-Year Experience With Polytraumatized Patients in a Level 1 Trauma Center
In this study patients who were admitted to our hospital with critical injuries were enrolled retrospectively from January 1992 to December 2019.
- Trial name
- NCT04723992
- Testing
- retrospective analysis
- Where
- Austria
- Volunteers
- 1,400 people
- Sponsor
- Medical University of Vienna
Polytrauma, Red Blood Cell Distribution Width
Red Blood Cell Distribution Width and Charlson Comorbidity Indeces in the Frail Polytraumatized Patient.
In this study patients who were admitted to our hospital with critical injuries were enrolled retrospectively from January 2012 to December 2015.
- Conditions
- Polytrauma, Red Blood Cell Distribution Width, Comorbidities and Coexisting Conditions
- Trial name
- NCT05221476
- Testing
- retrospective
- Volunteers
- 400 people
- Sponsor
- Medical University of Vienna
Trauma, Trauma Injury
An Observational Study to Evaluate the Safety and Efficacy of Humacyte's HAV for Arterial Replacement or Reconstruction in Ukrainian Patients With Life or Limb-threatening Vascular Trauma
Humacyte provided HAVs as humanitarian aid to Ukraine. This retrospective observational study is designed to collect data from patients in whom the HAVs have already been implanted on a humanitarian basis between June 2022 and…
- Conditions
- Trauma, Trauma Injury, Trauma, Multiple, Trauma Blunt
- Trial name
- NCT05873959
- Testing
- HAV implantation
- Where
- 3 sites in Ukraine
- Volunteers
- 17 people
- Sponsor
- Humacyte, Inc.
Multiple Trauma, Injury Traumatic
The BIG Score and In-Hospital Trauma Mortality
This study investigated the efficacy and reliability of the BIG score, calculated based on the base deficit (BD), International Normalized Ratio (INR), and Glasgow coma scale (GCS), in comparison with the GCS, Revised trauma…
- Trial name
- BIGstd (NCT06574464)
- Testing
- BIG SCORE, Glasgow coma scale, Revised Trauma Score
- Where
- Turkey (Türkiye)
- Volunteers
- 563 people
- Sponsor
- Haseki Training and Research Hospital
Metabolism, Trauma
ImpACt of Very High Protein Content Enteral nUtrition Formulas on Critically Ill MUltipLe trAuma paTiEnts
This prospective observational randomized study aims to determine energy, protein intake and gastrointestinal tolerance while using enteral nutrition formulas with very high protein content and enteral nutrition formulas with…
- Conditions
- Metabolism, Trauma, Nutritional Deficiency, Protein Malnutrition
- Trial name
- ACCUMULATE (NCT05647135)
- Testing
- Medical food
- Where
- Romania
- Volunteers
- 70 people
- Sponsor
- Romanian Society for Enteral and Parenteral Nutrition
Multi-organ Failure After Severe Trauma
Metabolic Reprogramming in Renal Tubular Cells in Acute Kidney Injury Following Severe Trauma
Severe trauma remains the leading cause of death in people under 50, and is associated with high morbidity, including severe disability, with a substantial socio-economic impact.
- Trial name
- METAKIT (NCT06167512)
- Where
- 2 sites in France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Traumatic Brain Injury, Posttraumatic Stress Disorder
Cognitively Augmented Behavioral Activation for Veterans With Comorbid TBI/PTSD
The primary objective of this study is to evaluate the efficacy of Cognitively Augmented Behavioral Activation (CABA), a new hybrid treatment for Veterans diagnosed with comorbid mild Traumatic Brain Injury (mTBI) and…
- Trial name
- CABA (NCT02391402)
- Testing
- Cognitively Augmented Behavioral Activation, Treatment as Usual
- Where
- 2 sites in United States
- Volunteers
- 73 people
- Sponsor
- VA Office of Research and Development