Clinical trials: Trauma, Brain
Hemiplegic Cerebral Palsy, Non-Accidental Traumatic Head Injury to Child
Intensive Group Based CIMT for Young Children
This project aims to investigate the effectiveness of an intensive, group-based Constraint Induced Movement Therapy (CIMT) program for young children ages 2-6 years with unilateral hemiparesis, or weakness on one side of the…
- Trial name
- NCT06330831
- Testing
- Intensive, Group Based Constraint Induced Therapy (CIMT)
- Volunteers
- 35 people
- Sponsor
- Rockhurst University
Brain Edema, Craniocerebral Trauma
A Comparison Between Two Techniques for Performing Decompressive Craniectomy
The purpose of this study is to compare two surgical techniques for a neurosurgical procedure used to treat cerebral edema (decompressive craniectomy): with watertight duraplasty vs.
- Conditions
- Brain Edema, Craniocerebral Trauma, Infarction, Middle Cerebral Artery
- Trial name
- NCT02594137
- Testing
- Without watertight duraplasty
- Volunteers
- 58 people
- Sponsor
- Hospital of the Restoration, Recife
Tinnitus
Telephone Tinnitus Education for Patients With Traumatic Brain Injury (TBI)
This study continues the investigators' efforts to develop tinnitus management protocols for Veterans. More specifically, this study developed and evaluated an adaptation of Progressive Tinnitus Management (PTM) for use as a…
- Trial name
- NCT01129141
- Testing
- Tele-PTM, Wait List Control
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- VA Office of Research and Development
Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE)
Intranasal AAV9-PHP.eB Gene Therapy in Cerebral Palsy (CP) & Hypoxic Ischemic Encephalopathy (HIE)
This international study, organized by Healing Hope International, is an observational registry designed to collect real-world data on participants living with chronic hypoxic ischemic encephalopathy (HIE) who receive an emerging…
- Conditions
- Hypoxic Brain Damage, Hypoxic Ischaemic Encephalopathy (HIE), Hypoxic Ischaemic Encephalopathy Due to Cardiac Arrest, Hypoxic Ischemic Encephalopathy of Newborn
- Trial name
- GEN-HOPE (NCT07264166)
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Healing Hope International
Disorder of Consciousness, Consciousness, Loss of
SeeMe: An Automated Tool to Detect Early Recovery After Brain Injury
Early prediction of outcomes after acute brain injury (ABI) remains a major unsolved problem. Presently, physicians make predictions using clinical examination, traditional scoring systems, and statistical models.
- Conditions
- Disorder of Consciousness, Consciousness, Loss of, Trauma, Brain, Traumatic Brain Injury
- Trial name
- NCT06083441
- Testing
- SeeMe, Coma Recovery Scale-Revised (CRS-R)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Traumatic Brain Injury
Effects of Exercise on Memory in Healthy and Brain-Injured Individuals
Background: Research has shown that one exercise session may improve a person s ability to recall information they learned before the exercise.
- Trial name
- NCT01939769
- Testing
- Exercise - Low-intensity exercise, Exercise - High-intensity exercise
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Sport Related Concussion
Salivary Biomarkers for Concussion
Concussion (CC) (also called mild head trauma), which accounts for 85% of all head injuries, is very common in professional and amateur athletes.
- Trial name
- SportCo (NCT06149351)
- Testing
- Bio-fluid analysis for the implementation of a diagnostic test for sport related concussion
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sys2Diag
Traumatic Brain Injury
Different Feeding in Traumatic Brain Injury Patients
This was a multicenter randomized controlled study of 98 severe Traumatic Brain Injury patients with tracheostomy. Patients enrolled were divided randomly into the observation group with Intermittent Oro-esophageal Tube Feeding…
- Trial name
- NCT06249022
- Testing
- Rehabilitation therapy, Intermittent Oro-esophageal Tube Feeding, Nasogastric tube feeding
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Zeng Changhao
Traumatic Brain Injury
Evaluation of Biomarkers of Traumatic Brain Injury
The primary objective of this study is to evaluate the utility of the Banyan UCH-L1/GFAP Detection Assay as an aid in the evaluation of suspected traumatic brain injury (Glasgow Coma Scale score 9-15) in conjunction with other…
- Trial name
- ALERT-TBI (NCT01426919)
- Testing
- Head CT scan and blood draw within 12 hours of injury
- Where
- 24 sites in United States, Germany and 1 more
- Volunteers
- 2,011 people
- Sponsor
- Banyan Biomarkers, Inc
Brain Injuries, Focal
VR Versus Task-Oriented Circuit Training on UL Sensorimotor in Children With Immature Brain Injury
To investigate and compare the effect of virtual reality and task-oriented circuit training on pinch grip and quality of life in children with with immature brain injury.
- Trial name
- NCT07827365
- Testing
- Virtual reality, Task-oriented circuit training
- Volunteers
- 44 people
- Sponsor
- October 6 University
Traumatic Brain Injury
A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury
The study is intended to cover two purposes: first, to develop a blood-based biomarker test for aiding the diagnosis of traumatic brain injury (TBI) in adult participants and for prognosis of outcome of TBI (CLIN12.1); and…
- Trial name
- NCT07455136
- Testing
- Blood sample collection
- Where
- 14 sites in United States
- Volunteers
- 2,000 people
- Sponsor
- Hoffmann-La Roche
Ventilator Associated Pneumonia
Antibiotic Prophylaxis for Early Ventilator-associated Pneumonia in Neurological Patients
This study seeks to assess whether coma patients really benefit from the use of antibiotics as a prophylactic for reducing the incidence of early ventilator-associated pneumonia in this population group.
- Trial name
- NAVPRO (NCT01118403)
- Testing
- Sultamicillin
- Where
- Colombia
- Sponsor
- Hospital Pablo Tobón Uribe
Bladder Outlet Obstruction, Multiple Sclerosis
GentleCath™ for Men Intermittent Catheter With FeelClean™ Technology
Male self catherterisng observational study.
- Conditions
- Bladder Outlet Obstruction, Multiple Sclerosis, Cauda Equina Syndrome, Enlarged Prostate With Lower Urinary Tract Symptoms
- Trial name
- NCT05470751
- Testing
- Intermittent self-catheterisation
- Where
- 16 sites in United States, France and 1 more
- Volunteers
- 72 people
- Sponsor
- ConvaTec Inc.
Traumatic Brain Injury, Posttraumatic Stress Disorder
Strategic Memory and Reasoning Training for Cognitive Problems
The focus of this study is to test a treatment program (Strategic Memory Advanced Reasoning Training; SMART) that was developed to address specific brain functions found to be crucial for the recovery following traumatic brain…
- Trial name
- SMART (NCT04554537)
- Testing
- SMART, Brain Health Workshop
- Volunteers
- 100 people
- Sponsor
- Dr. Kristin Samuelson
Brain Injuries
Noninvasive Brain Stimulation Training
Non-invasive cerebral stimulation techniques have shown potential in the treatment of neurological disorders such as chronic pain, Parkinson's disease, neglect, aphasia, memory, engine deficit and epilepsy In general…
- Trial name
- TrainingNIBS (NCT03228472)
- Testing
- non invasive brain stimulation
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Neuromed IRCCS
Stroke, Hip Fractures
Outcome of Rehabilitation of Older People in Primary Health Care
The Outcome of Multi-Disciplinary, Structured Rehabilitation of Older People in a District Inpatient Rehabilitation Centre is better than in a Standard Primary Health Care Rehabilitation Programme in Short Term Beds in Nursing…
- Conditions
- Stroke, Hip Fractures, Osteoarthritis, Chronic Disease
- Trial name
- NCT01457300
- Testing
- Rehabilitation
- Where
- 2 sites in Norway
- Volunteers
- 302 people
- Sponsor
- University of Oslo
Hemianopia, Brain Injuries, Traumatic
Restoration vs. Compensation in Neurovisual Rehabilitation of Visual Field Defects
Visual field defects (VFD) are a frequent effect of cerebral lesions especially after posterior cerebral artery stroke. The present study was conducted to compare effects of vision restoration training (VRT) and compensation…
- Trial name
- NCT04043429
- Testing
- Vision Restoration Training (VRT), Vision Exploration Training (VET)
- Where
- Germany
- Volunteers
- 86 people
- Sponsor
- University of Magdeburg
Aphasia, Traumatic Brain Injury
Narrative Comprehension by People With Acquired Brain Injury
The purpose of this two phase study is to evaluate comprehension by people with acquired brain injury. The phase 1 portion of the study will examine comprehension of narrative paragraphs under 3 conditions: (a) written text only…
- Trial name
- NCT03309930
- Testing
- Comprehension Acquired Brain Injury
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Miami University
Traumatic Brain Injury
Allogeneic Umbilical Cord Blood Therapy for Chronic TBI
This open label trial is conducted to investigate the efficacy and safety of umbilical cord blood therapy for chronic traumatic brain injury patients.
- Trial name
- NCT01451528
- Testing
- Allogeneic Umbilical Cord Blood
- Where
- South Korea
- Sponsor
- Bundang CHA Hospital
Bronchopulmonary Dysplasia
Ascorbyl Peroxide Association With Bronchopulmonary Dysplasia
Urinary ascorbyl peroxide level in the first week of life will be a good predictor of Bronchopulmonary dysplasia (BPD) in preterm infants less than 33 weeks of gestation.
- Trial name
- NCT01439295
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- St. Justine's Hospital