Clinical trials: Transferrin
Alcohol Abuse
Benefit of Carbohydrate Deficient Transferrin to Detect Chronic Alcohol Abuse in the Elderly
Alcohol misuse affects 5 million people in France. Even though the elderly are also concerned by this pathology, there is not much information about chronic alcohol misuse of this population in particular.
- Trial name
- Caesar (NCT02822911)
- Testing
- Alcohol Used Disorders Identification Test (AUDIT C), Carbohydrate deficient transferrin, Gamma glutamyl transpeptidase
- Where
- 2 sites in France
- Volunteers
- 194 people
- Sponsor
- Groupe Hospitalier de la Region de Mulhouse et Sud Alsace
Anemia, Iron Deficiency
Is Iron Deficiency the Cause of Anemia Among Women in Cambodia?
Globally, the most common cause of anemia is thought to be iron deficiency anemia (IDA). This was assumed to be the major cause of anemia in Cambodia, because Cambodian diets, which consist mainly of rice, lack iron-rich animal…
- Conditions
- Anemia, Iron Deficiency, Hemoglobin Disorder, Infection
- Trial name
- NCT02481375
- Testing
- Multiple micronutrients, Iron
- Where
- Cambodia
- Volunteers
- 809 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Iron Deficiency, Latent Iron Deficiency
Reticulocyte Hemoglobin Equivalent (RET-He) in Early Detection of Iron Deficiency Among Blood Donors and Its Potential Impact on Donor Eligibility and Transfusion Safety
Blood donation is essential for healthcare, but repeated whole-blood donation can deplete the body's iron stores. Standard pre-donation screening relies on hemoglobin levels to ensure donor safety; however, a drop in hemoglobin…
- Conditions
- Iron Deficiency, Latent Iron Deficiency, Blood Donors, Iron Deficiency Anemia
- Trial name
- NCT07861607
- Volunteers
- 300 people
- Sponsor
- Assiut University
Glioblastoma
Comparison of TransMID vs Standard Treatment of Cancerous Brain Tumors
Study Objectives: Primary Objective: To evaluate the efficacy of intratumoral/interstitial therapy with TransMID compared to best standard of care in patients with progressive and/or recurrent, non-resectable glioblastoma…
- Trial name
- NCT00088400
- Testing
- TransMID
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cardiac Glycogenosis, Cardiomyopathy
ATR 1072 in Participants With PRKAG2 Syndrome
ATR 1072 is an investigational medicine being studied in adults with PRKAG2 Syndrome. This study will evaluate the safety of ATR 1072 and how the body processes the drug.
- Conditions
- Cardiac Glycogenosis, Cardiomyopathy, Hypertrophic, Wolff-Parkinson-White Syndrome
- Trial name
- NCT07738107
- Testing
- ATR 1072
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Atrium Therapeutics
Iron-deficiency, Iron Deficiency Anemia
Iron Metabolism Disorders in Patients With Sepsis or Septic Shock.
Anemia is a common health problem. Depending on a geographical region, anemia affects even 50% of population. Among patients admitted to the intensive care unit (ICU) anemia may affect as much as 66% of patients.
- Conditions
- Iron-deficiency, Iron Deficiency Anemia, Anemia of Chronic Disease, Sepsis
- Trial name
- NCT05217836
- Testing
- ferritin; iron; transferrin; transferrin saturation; hemoglobin in reticulocyte; hepcidin
- Where
- Poland
- Volunteers
- 90 people
- Sponsor
- Medical University of Silesia
Hemochromatoses, Genetic
Transferrin Saturation and Asthenia in Hemochromatosis
Observational study.
- Trial name
- HEMOSAT (NCT03356548)
- Where
- France
- Volunteers
- 260 people
- Sponsor
- Rennes University Hospital
Alteration of Mitochondrial Membrane, Type2 Diabetes
Mitochondrial Effects of C18:0 Supplementation in Humans
The purpose of this crossover study is to determine whether nutritional supplementation of C18:0 in humans has mitochondrial effects as shown in Drosophila and human cell culture.
- Conditions
- Alteration of Mitochondrial Membrane, Type2 Diabetes, Fatty Acid Deficiency
- Trial name
- NCT02957838
- Testing
- C18:0, mock
- Where
- Germany
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Anemia, Critical Illness
Hepcidine and Iron Deficiency in Critically Ill Patients
Anaemia is very frequent among critically ill patients, concerning more than 60 % of them at admission and more than 80% at intensive care unit discharge.
- Conditions
- Anemia, Critical Illness, Hospitalized for 5 Days or More
- Trial name
- HEPCIDANE (NCT02276690)
- Testing
- hepcidin, ferritin and transferrin saturation
- Where
- France
- Volunteers
- 408 people
- Sponsor
- University Hospital, Montpellier
Chronic Myeloproliferative Disorders, Leukemia
Monoclonal Antibody Therapy in Treating Patients With Advanced Cancer
RATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00003082
- Testing
- monoclonal antibody A27.15, monoclonal antibody E2.3
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- University of Arizona
Kidney Failure, Anemia
Iron Sucrose in Stage 3/4 Kidney Disease
One of the complications of late stage kidney disease is the development of a low red blood cell count (anaemia/low haemoglobin concentration).
- Trial name
- NCT00202345
- Testing
- Iron sucrose
- Where
- 6 sites in Australia
- Volunteers
- 120 people
- Sponsor
- Melbourne Health
Beta Thalassemia Major
An Algorithm to Start Iron Chelation in Minimally Transfused Young Beta-thalassemia Major Patients
A prospective randomized study on Safety, Tolerability and Efficacy of oral Low dose DFP (50 mg/kg/day) in minimally transfused B-TM after 5 transfusions when SF reaches 500 ng/m and with either appearance of LPI > 0.2 or TSAT…
- Trial name
- NCT02173951
- Testing
- Deferiprone
- Where
- Egypt
- Volunteers
- 64 people
- Sponsor
- Ain Shams University
Effect of Iron Status on Occurrence of NTBI
Effect of Iron Status on Occurrence of Non-transferrin-bound Iron (NTBI) in Serum in Response to an Oral Iron Load
This study aims to investigate a possible effect of iron status on temporary build-up of non-transferrin bound iron (NTBI) in healthy volunteers upon iron supplementation.
- Trial name
- NCT02831712
- Testing
- Ferrous Fumarate
- Where
- Singapore
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Thomas Walczyk
Parkinson's Disease (PD), Parkinsonism
Identifying Biomarkers of Parkinson's Disease Using Magnetic Resonance Imaging (MRI)
This study is designed to determine if magnetic resonance imaging (MRI) measures can be used to diagnose and monitor the progression of Parkinson's disease (PD) while distinguishing between PD and parkinsonisms [conditions that…
- Conditions
- Parkinson's Disease (PD), Parkinsonism, Progressive Supranuclear Palsy (PSP), Multiple System Atrophy (MSA)
- Trial name
- NCT01888185
- Where
- United States
- Volunteers
- 290 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Hemodialysis, Anemia in End Stage Renal Disease
Comparing Reticulocyte Hemoglobin and Transferrin Saturation to Guide Iron Treatment in People on Dialysis
The goal of this clinical trial is to find out which method is better for guiding iron treatment in adult patients with end-stage kidney disease (ESKD) on hemodialysis who have anemia.
- Trial name
- NCT06906835
- Testing
- RET-He-Guided Iron Supplementation, TSAT-Guided Iron Supplementation, Common
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- King Chulalongkorn Memorial Hospital
End Stage Renal Disease, Chronic Kidney Diseases
Ferric Citrate in ESRD Pilot Project
This research study is for participants that have End Stage Renal Disease (ESRD). ESRD is the last stage of chronic kidney disease.
- Trial name
- NCT03055598
- Testing
- Ferric Citrate
- Where
- 2 sites in United States
- Volunteers
- 30 people
- Sponsor
- Sreedhar Mandayam
Anemia, Renal Failure
Heme Iron Polypeptide for Iron Deficiency Anemia in Chronic Renal Failure
The purpose of this study is to determine if oral Heme Iron Polypeptide is as effective as intravenous (IV) iron sucrose in the treatment of iron-deficiency anemia for patients with chronic kidney disease.
- Trial name
- NCT00318812
- Testing
- Heme Iron Polypeptide (Proferrin), Iron sucrose (Venofer)
- Where
- Canada
- Volunteers
- 55 people
- Sponsor
- Ottawa Hospital Research Institute
Haemochromatosis
Impact of Transferrin Saturation Guided Maintenance Treatment on Quality of Life in HFE Haemochromatosis
Patients in maintenance treatment for HFE hemochromatosis since at least one year will be included in a two year study period and randomized in two groups experimental and control group.
- Trial name
- Quali-SAT (NCT04779593)
- Testing
- Clinical examination, SF36 questionnaire, AIMS2_SF questionnaire
- Where
- 12 sites in France
- Volunteers
- 239 people
- Sponsor
- Rennes University Hospital
Iron Deficiency Anemia
Efficacy and Safety Study of Iron Sucrose and Oral Iron Acetyl-transferrin Hydroglycerin
multi-center, prospective, randomized, open-labeled, active-drug-controlled, two-parallel-group-comparison(venoferrun group vs Bolgre group)study
- Trial name
- NCT00802139
- Testing
- venoferrum(iron sucrose), Bolgre (Iron acetyl-transferase)
- Where
- 3 sites in South Korea
- Volunteers
- 58 people
- Sponsor
- JW Pharmaceutical
Alcohol Dependence, Chronic Hepatitis C
Study of the Effects of Motivational Enhancement Therapy on Alcohol Use in Chronic Hepatitis C Patients
The purpose of this study is to determine whether motivational enhancement therapy (MET) reduces alcohol use in a population of HCV-infected veterans who are currently drinking alcohol and have alcohol disorders.
- Trial name
- NCT00596960
- Testing
- Motivational Enhancement Therapy (MET), Health education
- Where
- 2 sites in United States
- Volunteers
- 139 people
- Sponsor
- US Department of Veterans Affairs