Clinical trials: Transcutaneous Spinal Stimulation
Spinal Cord Injury, Neurogenic Bladder
The Effects Upon the Bladder of Transcutaneous Tibial Nerve Stimulation in Acute Traumatic Spinal Cord Injury
The purpose of this research study is to evaluate the effects upon the bladder of electric stimulation of the leg's tibial nerve in people with acute spinal cord injury with an intervention called transcutaneous tibial nerve…
- Trial name
- NCT02573402
- Testing
- Transcutaneous Tibial Nerve Stimulation, Control
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Injury Cervical
Combining Spinal Cord Transcutaneous Stimulation and Activity-based Training in Inpatient Rehabilitation to Facilitate Upper Limb Function of Individuals with Acute to Subacute Cervical Spinal Cord Injury
The purpose of this clinical trial is to understand the safety and practicality of using spinal cord transcutaneous (through the skin) stimulation in an inpatient setting as well as how the combination of activity-based training…
- Trial name
- NCT06773286
- Testing
- Active Stimulation, Training only
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kessler Foundation
Spinal Cord Injuries
Transcutaneous Spinal Cord Stimulation Combined With Arm Bike for Cardiovascular Recovery in SCI
Spinal cord injury (SCI) can make it hard for the body to self-regulate some of its automatic functions like blood pressure, breathing, and heart rate.
- Trial name
- NCT06313515
- Testing
- Transcutaneous Spinal Cord Stimulation, Arm-crank bike exercise
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Washington
Spinal Cord Injuries
Neuromodulation of Spinal Locomotor Circuitry to Elicit Stepping After Pediatric Spinal Cord Injury
Spinal cord injury (SCI) results in damage to the descending neural pathways and leads to the immediate dysfunction of multiple physiological systems below the level of injury.
- Trial name
- NCT04077346
- Testing
- Biostim-5 transcutaneous spinal stimulator, Transcutaneous Spinal Stimulator + Activity Based Locomotor Training
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- University of Louisville
Stroke
Noninvasive Spinal Stimulation in Stroke
This is a randomized control trial that will evaluate the effectiveness of transcutaneous (non-invasive) spinal cord stimulation on gait and balance function for individuals with hemiplegia due to stroke.
- Trial name
- NCT03714282
- Testing
- Noninvasive spinal stimulation with gait training, Conventional gait training
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injuries
Influence of Transcutaneous Spinal Stimulation Intensity on Spasticity After SCI
Transcutaneous spinal stimulation (TSS) is a form of electrical stimulation delivered over the skin of the spine that may be valuable for reducing spasticity without the side effects of antispasticity medications.
- Trial name
- NCT04243044
- Testing
- Transcutaneous spinal stimulation
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Shepherd Center, Atlanta GA
Healthy Participants
Testing Non-Invasive Spinal Stimulation Devices
The purpose of this study is to compare updated spinal stimulation devices with the spinal stimulation device that is currently used.
- Trial name
- STEPSS/ARC-ex (NCT07217314)
- Testing
- Spinal Stimulation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Gail Forrest
Spinal Cord Injuries (SCI), Detrusor Overactivity
The Effectiveness of Transcutaneous Sacral Neuromodulation Techniques-Magnetic Stimulation and Electrical Stimulation-on Detrusor Overactivity in Patients With Spinal Cord Injury
The goal of this prospective, randomized clinical trial is to compare the efficacy and safety of transcutaneous sacral magnetic stimulation versus sacral electrical stimulation for detrusor overactivity in 40 male and female…
- Trial name
- NCT07578532
- Testing
- Transcutaneous Sacral Electrical Stimulation, Transcutaneous sacral magnetic stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Ankara City Hospital Bilkent
Spinal Cord Injuries (Complete and Incomplete), Spinal Cord Injury
Electrical Neuromodulation for Modifying Spinal Network Involved in Spasticity
Muscle stiffness and muscle spasms are common after spinal cord injury. They can interfere with washing and dressing, moving between the bed and a wheelchair, walking, and sleep, and they can cause pain.
- Conditions
- Spinal Cord Injuries (Complete and Incomplete), Spinal Cord Injury, Spinal Cord Injury Cervical, Spinal Cord Injury Thoracic
- Trial name
- NCT07792616
- Testing
- Transcutaneous spinal stimulation at 30 Hz, Transcutaneous spinal stimulation at 75 Hz, Tizanidine
- Where
- 2 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Mississippi Medical Center
Cervical Radiculopathy, Cervical Spondylosis
Transcutaneous Auricular Vagus Nerve Stimulation Combined With Cervical Epidural Injection for Cervical Radiculopathy
This is a prospective, randomized, double-blinded, sham-controlled trial conducted to investigate the efficacy and safety of transcutaneous auricular vagus nerve stimulation (taVNS) combined with cervical epidural injection in…
- Conditions
- Cervical Radiculopathy, Cervical Spondylosis, Radicular Pain
- Trial name
- NCT07557823
- Testing
- Transcutaneous Auricular Vagus Nerve Stimulation (taVNS), Cervical Epidural Injection
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Spinal Cord Injury
Exoskeletal-assisted Walking Combined With Transcutaneous Spinal Cord Stimulation: Effect on Imaging and Serum Biomarkers of Skeletal Muscle Mass and Bone Strength.
Immobilization following spinal cord injury (SCI) results in muscle and bone loss below the level of injury, which ultimately predisposes to fracture at several sites throughout the legs and can lead to several medical…
- Trial name
- NCT07418398
- Testing
- Exoskeleton-Assisted Walking (EAW), Active Transcutaneous Spinal Cord Stimulation (tSCS)
- Where
- 2 sites in United States
- Volunteers
- 24 people
- Sponsor
- VA Office of Research and Development
Spina Bifida
Transcutaneous Tibial Nerve Stimulation (TTNS) Treatment in Spina Bifida Pediatric Patients With Neurogenic Bladder
The purpose of this research study is to determine the effectiveness of a treatment called "transcutaneous tibial nerve stimulation" or "TTNS" in the treatment of urinary leakage for patients with spina bifida.
- Trial name
- NCT06025734
- Testing
- Transcutaneous Tibial Nerve Stimulation (TTNS) treatment
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Texas Southwestern Medical Center
Anesthesia
Effect of Acupoint Electrical Stimulation on Incidence of Hypotension After Spinal Anesthesia
This study is intended to include elderly patients who are selected to undergo lower limb and pelvic orthopedic surgery under spinal anesthesia.
- Trial name
- NCT05716399
- Testing
- Transcutaneous electric stimulation pretreatment, Transcutaneous acupoint electrical stimulation treatment, Transcutaneous acupoint pseudo electric stimulation
- Volunteers
- 111 people
- Sponsor
- Shanghai Tongji Hospital, Tongji University School of Medicine
Spinal Cord Injuries
tSCS + UL Robotics Training in SCI Patients
This study is aimed to evaluate whether transcutaneous spinal cord stimulation (tSCS) can augment upper limb robotic training (ULRT) to improve functional mobility in participants with chronic spinal cord injuries.
- Trial name
- NCT07432321
- Testing
- ULRT + tSCS + conventional occupational therapy, ULRT + conventional occupational therapy
- Where
- Singapore
- Volunteers
- 6 people
- Sponsor
- National University Hospital, Singapore
Stroke, Spinal Cord Injury
Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation
The goal of this clinical study is to investigate the potential synergy between non-invasive brain and spinal cord stimulation administered during a cognitive-motor task, in terms of their immediate effects on sensorimotor and…
- Conditions
- Stroke, Spinal Cord Injury, Able Bodied
- Trial name
- BrainSpineStim (NCT07334977)
- Testing
- tDCS, tSCS, Cognitive-Motor Task
- Where
- 2 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre National de la Recherche Scientifique, France
Major Depressive Disorder
Spinal Cord Stimulation for the Treatment of Major Depressive Disorder
This pilot clinical trial will evaluate the efficacy and safety of transcutaneous direct current stimulation (tsDCS) in major depressive disorder.
- Trial name
- SPIDEP (NCT03433339)
- Testing
- Active transcutaneous spinal direct current stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Cincinnati
Gait Disorders, Neurologic
Transcutaneous Magnetic Spinal Cord Stimulation for Freezing of Gait in Parkinson's Disease
Dopaminergic drugs partially alleviate gait problems in Parkinson's disease, but the effects are not sustained in the long-term.
- Trial name
- TMS (NCT04783493)
- Testing
- Non-invasive magnetic stimulation of the spinal cord, Coil will not be connected to the stimulation device
- Where
- Brazil
- Volunteers
- 38 people
- Sponsor
- University of Sao Paulo General Hospital
Spinal Cord Injuries, Neurogenic Detrusor Overactivity
TTNS in SCI Patients With Neurogenic Detrusor Overactivity
This is a prospective, single-arm, pilot study to assess effectiveness and tolerability of transcutaneous tibial nerve stimulation (TTNS) in managing neurogenic detrusor overactivity in spinal cord injury patients.
- Trial name
- NCT07785258
- Testing
- TTNS
- Where
- Singapore
- Volunteers
- 12 people
- Sponsor
- National University Hospital, Singapore
Spinal Cord Injury Cervical, Spinal Cord Injuries (SCI)
Transcutaneous Spinal Cord Stimulation for Blood Pressure Augmentation Immediately After Spinal Cord Injury
In the treatment of spinal cord injury (SCI) patients in the hyperacute setting, it is imperative to closely control mean arterial pressure (MAP) to ensure adequate spinal cord perfusion in the absence of properly functioning…
- Conditions
- Spinal Cord Injury Cervical, Spinal Cord Injuries (SCI), Spinal Cord Injury (SCI), Initial Encounter
- Trial name
- Stim for MAP (NCT07887373)
- Testing
- Spinal Cord Stimulation
- Volunteers
- 20 people
- Sponsor
- Markey Olson
Myelomeningocele, Spina Bifida
Transcutaneous Spinal Stimulation for Children and Youth With Spina Bifida
A study to use transcutaneous spinal cord stimulation to characterize sensorimotor deficits in a pediatric population of individuals with spina bifida.
- Trial name
- NCT06918119
- Testing
- Transcutaneous stimulation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic