Clinical trials: Transcutaneous Spinal Stimulation
Cerebral Palsy, Spasticity
Spinal Cord Stimulation for Children With Cerebral Palsy
The goal of this clinical trial is to help understand spinal cord excitability in children with cerebral palsy compared to neurologically typical children.
- Trial name
- NCT07516067
- Testing
- Transcutaneous Spinal Cord Stimulation (tSCS)
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Martin Piazza
Stroke, Spinal Cord Injury
Synergistic Effect of Non-invasive Brain and Spinal Cord Stimulation
The goal of this clinical study is to investigate the potential synergy between non-invasive brain and spinal cord stimulation administered during a cognitive-motor task, in terms of their immediate effects on sensorimotor and…
- Conditions
- Stroke, Spinal Cord Injury, Able Bodied
- Trial name
- BrainSpineStim (NCT07334977)
- Testing
- tDCS, tSCS, Cognitive-Motor Task
- Where
- 2 sites in France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Centre National de la Recherche Scientifique, France
Spinal Cord Injuries (SCI), Spinal Cord Injury
Transcutaneous Spinal Electrical Stimulation to Improve Exercise Function After Spinal Cord Injury.
Our overall objective is to decrease the prevalence of multiple sedentary-related diseases that are secondary consequences of spinal cord injury (SCI).
- Conditions
- Spinal Cord Injuries (SCI), Spinal Cord Injury, Spinal Injury
- Trial name
- NCT07692191
- Testing
- Transcutaneous spinal electrical stimulation (TSES)
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Traumatic Brain Injury, TBI (Traumatic Brain Injury)
Cervical Transcutaneous SCS for TBI
The goal of this study is to test the effects of non-invasive electrical stimulation of the spinal cord (called transcutaneous spinal cord stimulation, or tSCS) on arm and hand movement in people with motor impairments after a…
- Trial name
- NCT07147816
- Testing
- Transcutaneous electrical stimulation of the cervical spinal cord (tSCS)
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Roberto de Freitas
Inspiratory Strength Training (IST), Transcutaneous Spinal Stimulation
Rehab and Mechanical Ventilation
The goal of this research study is to evaluate the effects of a single session of rehabilitation in healthy adults, before noninvasive mechanical ventilation (MV). MV can help support breathing function during sleep or illness.
- Conditions
- Inspiratory Strength Training (IST), Transcutaneous Spinal Stimulation, Sham Spinal Stimulation
- Trial name
- REHAB-MV (NCT07427121)
- Testing
- Spinal cord stimulation, Inspiratory Strength Training
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Florida
Healthy Participants
Testing Non-Invasive Spinal Stimulation Devices
The purpose of this study is to compare updated spinal stimulation devices with the spinal stimulation device that is currently used.
- Trial name
- STEPSS/ARC-ex (NCT07217314)
- Testing
- Spinal Stimulation
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Gail Forrest
Spinal Cord Injuries (SCI), Orthostatic Hypotension, Dysautonomic
Cardiovascular Function and Response to Stimulation Within the First Year After Spinal Cord Injury
The study aims to explore how cardiovascular function changes in the first year after a spinal cord injury, and to see how different treatments, like spinal stimulation through the skin (transcutaneous spinal stimulation), affect…
- Conditions
- Spinal Cord Injuries (SCI), Orthostatic Hypotension, Dysautonomic, Cardiovascular, Transcutaneous Spinal Stimulation
- Trial name
- NCT06841198
- Testing
- spinal cord transcutaneous stimulation, Ice testing
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Spinal Cord Injury
AI-Powered Closed-Loop Multielectrode Transcutaneous Spinal Cord Stimulation: Real-Time Adjustments for Enhanced Motor Recovery in Spinal Cord Injury (AIM RECOVER)
Spinal cord injury (SCI) often results in persistent motor deficits that are inadequately addressed by conventional rehabilitation.
- Trial name
- AIM RECOVER (NCT07452133)
- Testing
- Dynamic stimulation, Static stimulation
- Where
- Singapore
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Singapore General Hospital
Hypotension
Transcutaneous Electrical Acupoint Stimulation (TEAS) on Prevention Hypotension in Elderly
Despite prophylactic measures, hypotension remains a common side-effect of spinal anesthesia. Electroacupuncture influences hemodynamics.
- Trial name
- NCT05272033
- Testing
- Transcutaneous Electrical Acupoint Stimulation
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Konya Meram State Hospital
Spinal Cord Injuries
EMG Triggered Closed-Loop Stimulation for Spinal Cord Injury Individuals
Most individuals with spinal cord injury (SCI) have residual nerve circuits. The investigators aim to strengthen those circuits to improve motor recovery after injury.
- Trial name
- NCT03806023
- Testing
- hand movements (signals from thumb muscle) triggered PNS and TMS
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Bronx VA Medical Center
Healthy
Non-invasive Stimulation on Central Nervous System Excitability
A crossover trial with healthy volunteers will be conducted. Six sessions will be performed once a week in a counterbalanced order and at least with seven days washout period to minimize carry-over effects.
- Trial name
- NCT02659826
- Testing
- anodal tsDCS, cathodal tsDCS, Gait training
- Where
- Brazil
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Pernambuco
Spinal Cord Injuries
Spinal Stimulation + FES-Assisted Cough Training in SCI
The overall objective of this proposal is to determine if transcutaneous spinal cord stimulation (tSCS) delivered concurrently with functional electrical stimulation (FES)-assisted cough training (FES-Cough) is an effective…
- Trial name
- NCT07683780
- Testing
- tSCS combined with FES-Cough
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Milap Sandhu
Spinal Cord Injuries
Segmental Mechanisms of Transcutaneous Spinal Cord Stimulation for Spasticity Control
The aim of the pilot study is to gain first insights into the interaction of transcutaneous spinal cord stimulation with the altered activity of intraspinal circuits associated with spinal spasticity.
- Trial name
- SCS_CorE_AT (NCT03886857)
- Testing
- transcutaneous spinal cord stimulation
- Where
- 2 sites in Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Peter Lackner
Amyotrophic Lateral Sclerosis
Cervical Electrical Stimulation for ALS
Veterans are at higher risk than non-Veterans of falling ill with amyotrophic lateral sclerosis (ALS). ALS causes degeneration of motor neurons in both the brain and the spinal cord.
- Trial name
- NCT03411863
- Testing
- CES at rest, CES plus active hand or wrist movements
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Healthy Aging, Fatigue
Neuromodulation and Fatigue
In this project, we aim to determine any potential effects of a weak electrical current applied to the neck or thoracic area on functional capacity and muscle activation.
- Trial name
- NCT05487131
- Testing
- electrical stimulation
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Chronic Low-back Pain
Transcutaneous Spinal Cord Stimulation for Chronic Low Back Pain
As a leading cause of disability worldwide, chronic low back pain (cLBP) represents a significant medical and socioeconomic problem with estimated health care spending of $87 billion/annually.
- Trial name
- NCT05265000
- Testing
- tSpinalStim
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Pain
Non-invasive Modulation of Spinal Cord Nociceptive Reflexes
The aims of this study are threefold. First, to investigate whether spinal nociceptive processing - represented here by the nociceptive flexion reflex (NFR) - is influenced by thoracic transcutaneous spinal direct current…
- Trial name
- NCT05711498
- Testing
- Transcutaneous spinal direct current stimulation (tsDCS)
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Max Planck Research Group Pain Perception
Transcutaneous Electrical Nerve Stimulation, Spinal Cord Stimulation
Therapist-dependent Dose of Spinal TENS
The intensity used during transcutaneous electrical nerve stimulation (TENS) in both, clinical practice and research studies, is often based on subjective commands such as "strong but comfortable sensation".
- Conditions
- Transcutaneous Electrical Nerve Stimulation, Spinal Cord Stimulation, Dose-response Relationship
- Trial name
- NCT03179488
- Testing
- Spinal TENS
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Motor Activity
Transcutaneous Spinal Cord Stimulation in Healthy Subjects to Activate Central Pattern Generator
The purpose of this study is to determinate whether the application of transcutaneous spinal cord stimulation produce changes in the excitability of alpha moto neurone in healthy volunteers.
- Trial name
- NCT04241406
- Testing
- Transcutaneous spinal cord stimulation
- Where
- 3 sites in Spain
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Healthy Volunteers, Spinal Cord Injury
Chronic Transcutaneous Stimulation to Promote Motor Function and Recovery in Individuals With Paralysis or Paresis
This is an early feasibility trial to determine whether transcutaneous neuromuscular electrical stimulation, with or without transcutaneous spinal cord stimulation, using an investigational neurostimulation device improves…
- Conditions
- Healthy Volunteers, Spinal Cord Injury, Stroke, Paralysis
- Trial name
- NCT04755699
- Testing
- Transcutaneous Electrical Stimulation
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Northwell Health