Clinical trials: Transcranial Electric Stimulation
Parkinson' Disease
Effects of Physical Exercise Combined With Transcranial Direct Current Stimulation in Parkinson's Disease
A controlled, blinded, and randomized clinical study will be carried out in a large sample of people with Parkinson's disease, where the combined effects of physical exercise and transcranial direct curren stimlation (tDCS) on…
- Trial name
- ExtDCSPARK (NCT07524400)
- Testing
- real tDCS and exercise, Exercise
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Parkinson Disease, Depressive Symptoms
Low Voltage Electrical Stimulation for Depression in Parkinson's Patients
The goal of this clinical trial is to determine the relative efficacy of fMRI model guided Transcranial Direct Current Stimulation (mgTDCS) in improving the depressive symptoms of patients with Parkinson's Disease (PD).
- Trial name
- LVESDIPP (NCT06467695)
- Testing
- BIOPAC Stimsola
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of South Alabama
Stroke, Acute
Transcranial Direct Current Stimulation as a Neuroprotection in Acute Stroke
This proposal is a prospective, single-center, dose-escalation safety, tolerability, feasibility and potential efficacy study of transcranial direct current stimulation (tDCS) in acute stroke patients with substantial salvageable…
- Trial name
- TESSERACT (NCT03574038)
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of California, Los Angeles
Traumatic Brain Injury
Application of Trans Cranial Direct Current Stimulation for Executive Dysfunction After Traumatic Brain Injury
Traumatic brain injury (TBI) particularly affects the frontal lobes and patients often suffer from executive dysfunction and behavioral disturbances.
- Trial name
- NCT02331615
- Testing
- neuroConn_CE_DC-STIMULATOR
- Where
- Israel
- Volunteers
- 8 people
- Sponsor
- Loewenstein Hospital
Cognitive Impairment, Motoric Cognitive Risk Syndrome
Pre-FRONTal Brain STability, Key for Action Against Disability in AGing
Cognitive and mobility impairments are critical contributors to dementia and disability in older adults, and can be caused by neurodegenerative and neurovascular changes at the pre-frontal (PF) brain areas.
- Trial name
- FRONT STAGE (NCT04115215)
- Testing
- Physical exercise (PE), Transcranial current stimulation (tCS), Control
- Where
- 5 sites in Spain
- Volunteers
- 93 people
- Sponsor
- Parc Sanitari Pere Virgili
Healthy Volunteers
Measuring the Latency Connectome in the Central Nervous Systems Using Neuroimaging and Neurophysiological Techniques
Background: Little is known about the time it takes for nerve signals to go from one area of the brain to another. Using advanced methods for brain research, researchers want to look at the time it takes to send messages between…
- Trial name
- NCT03223636
- Testing
- TMS, MRI
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Migraine Disorders
tDCS for the Treatment of Migraine
The aim of this study is to evaluate an optimized protocol of tDCS that normalize the lack of habituation and efficiency of inhibitory cortical circuits in migraine patients.
- Trial name
- NCT02562196
- Testing
- tdcs
- Where
- Brazil
- Volunteers
- 14 people
- Sponsor
- Universidade Federal de Pernambuco
Self-Injurious Behavior, Self Harm
Treating Self Injurious Behavior: A Novel Brain Stimulation Approach
The purpose of this study is to explore the tolerability and effectiveness of transcranial direct current stimulation (tDCS) as a potential treatment for non-suicidal self-injury (NSSI).
- Conditions
- Self-Injurious Behavior, Self Harm, Self-injury, Self-inflicted Injury
- Trial name
- NCT04244786
- Testing
- Transcranial direct current stimulation, No intervention
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- New York State Psychiatric Institute
Healthy, Schizophrenia
Modulating Human Cortical Plasticity With Transcranial Electrical Stimulation
Experience dependent plasticity is a fundamental property of the brain. It allows neural systems to adapt in response to environmental input and subserves the vital functions of learning and memory.
- Trial name
- NCT03114488
- Testing
- tDCS
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Stroke, Cognition Disorders
The Effect of tDCS Combined With TMS on Cognitive Impairment and Motor Function After Stroke
This clinical trial aims to investigate whether transcranial electrical stimulation (tDCS) combined with transcranial magnetic stimulation(TMS) has an impact on the cognitive and motor functions of stroke patients, and to…
- Trial name
- NCT07573475
- Testing
- occupational therapy, real tDCS, real TMS
- Where
- China
- Volunteers
- 24 people
- Sponsor
- Ke Dong, MD
Stroke
High-definition Transcranial Electrical Stimulation for Upper Extremity Rehabilitation
Transcranial electrical stimulation (tCES) is a non-invasive and safe treatment, which uses a low direct current or alternating current to change the excitability of the cerebral cortex.
- Trial name
- NCT04278105
- Testing
- HD-tCES, Upper extremity rehabilitation
- Where
- 3 sites in Taiwan
- Volunteers
- 24 people
- Sponsor
- Taipei Medical University
Alzheimer Disease
Digital Twins for Model-driven Non-invasive Electrical Brain Stimulation
The purpose of this study is to obtain preliminary data in advance of a larger clinical trial designed to test whether repeated, daily sessions of at-home transcranial alternating current stimulation (tACS) can lead to a…
- Trial name
- NEUROTWIN (NCT06826261)
- Testing
- transcranial alternating current stimulation
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Major Depression Disorder
Home tDCS for the Treatment of Major Depression.
The purpose of this multicentric randomized controlled trial is to compare the effectiveness and safety of home-based tDCS for the treatment of major depression versus tDCS treatment in a healthcare centre, and explore the…
- Trial name
- NCT07510880
- Testing
- Accelerated protocol of home Transcranial direct current stimulation, Conventional protocol of home Transcranial direct current stimulation, Conventional protocol of in person Transcranial direct current stimulation
- Where
- 3 sites in Spain
- Volunteers
- 198 people
- Sponsor
- Ionclinics & Deionic SL
Acute Ischemic Stroke
Transcranial Direct Current Stimulation as a Neuroprotection in Acute Stroke Before and After Thrombectomy
This proposal is a prospective, single-center, dose-escalation safety, tolerability, feasibility and potential efficacy study of transcranial direct current stimulation (tDCS) in acute stroke patients with substantial salvageable…
- Trial name
- TESSERACT-BA (NCT04061577)
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- University of California, Los Angeles
Cerebrovascular Accident
Neural Mechanisms and Efficacy of Dual Neurotechnology-aided Mirror Therapy in Chronic Stroke: Neural and Motor Plasticity, Movement Performance, Daily Function, and Quality of Life
Mirror therapy (MT) has been demonstrated, in terms of neuroplasticity, to improve sensorimotor function of paretic upper extremity (UE) in chronic stroke patients.
- Trial name
- NCT04326205
- Testing
- transcranial direct current stimulation, tDCS, functional electrical stimulation, FES, no stimulation
- Where
- Taiwan
- Volunteers
- 112 people
- Sponsor
- Chang Gung Memorial Hospital
Dystonic Disorders
Transcranial Magnetic Stimulation and Electrical Stimulation of Nerves to Study Focal Dystonia
This study will use transcranial magnetic stimulation (TMS) and electrical stimulation of nerves to examine how the brain controls muscle movement in focal hand dystonia (writer's cramp).
- Trial name
- NCT00050024
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Healthy Subjects (HS)
Aftereffects of PES Preconditioned with RTMS on the Human Pharyngeal Motor Cortex
The goal of this interventional study is to optimize the excitatory brain effects of combined neuromodulatory therapies on swallowing areas of the brain.
- Trial name
- NCT06884488
- Testing
- repetitive transcranial magnetic stimulation (Magstim Super Rapid stimulator, The Magstim Company Ltd, Whitland, UK), pharyngeal electrical stimulation (Digitimer model DS7; Welwyn-Garden City, Herts, UK)
- Where
- United Kingdom
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Stroke, Cognitive Deficit
Transcranial Direct Current Stimulation (tDCS) in Post-Stroke Working Memory Deficits
The purpose of this study is to test the effects of tDCS (Transcranial Direct Current Stimulation) on stroke patients with working memory problems.
- Conditions
- Stroke, Cognitive Deficit, Cognitive Impairment, Short-Term Memory Impairment
- Trial name
- TDCS-PSMWD (NCT03034109)
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Stony Brook University
Pontine Infarction
Effect of TDCS Combined with Intraoral Electrical Stimulation
Objective: To investigate the clinical efficacy of transcranial direct current stimulation (tDCS) combined with intraoral electrical stimulation in patients with dysphagia after pontine infarction.
- Trial name
- NCT06852040
- Testing
- Intraoral induction electrical stimulation therapy, tDCS treatment, tDCS combined with intraoral induction electrical stimulation
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Xuehai Lv
Pain, Visceral Pain
TMS for the Treatment of Pancreatic Cancer Pain
This is a phase II study that aims to investigate prospectively a new therapy for a cohort of patients with chronic pain attributed to pancreatic cancer.
- Conditions
- Pain, Visceral Pain, Pancreatic Cancer
- Trial name
- NCT00324428
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Beth Israel Deaconess Medical Center