Clinical trials: Transcranial Direct Current Stimulation
Stroke
Cortical Priming to Optimize Gait Rehabilitation Post Stroke
Over four million stroke survivors currently living in the United States are unable to walk independently in the community. To increase the effectiveness of gait rehabilitation, it is critical to develop therapies that are based…
- Trial name
- NCT03492229
- Testing
- tDCS, AMT, Treadmill training
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of Illinois at Chicago
Post-traumatic Stress Disorder
Post-traumatic Stress Disorder Treatment Using Transcranial Direct Current Stimulation (tDCS) Enhancement of Trauma-focused Therapy : a Two-arm Randomized Controlled Multicentric Study.
Post-Traumatic Stress Disorder (PTSD) is an anxiety disorder that can develop after exposure to a terrifying event or ordeal in which there was the potential for or actual occurrence of grave physical harm.
- Trial name
- T-TREAt (NCT02900053)
- Testing
- tDCS
- Where
- 5 sites in France
- Volunteers
- 63 people
- Sponsor
- University Hospital, Tours
Obesity
Noninvasive Neuromodulation of the Prefrontal Cortex in Subjects With Obesity
The overall goal of this proposal is to evaluate the efficacy of transcranial direct current stimulation (tDCS), a noninvasive neuromodulation technique, to facilitate weight loss and weight loss maintenance in obesity.
- Trial name
- NCT02953353
- Testing
- Active transcranial direct current stimulation (tDCS), Hypocaloric diet
- Where
- 3 sites in United States, Brazil
- Volunteers
- 38 people
- Sponsor
- University of Sao Paulo
Parkinson's Disease
Open Label Treatment With tDCS for Parkinson's and Related Disorders for Improvement of Speech, Gait and Mood
This research will help us to understand whether transcranial direct current stimulation (tDCS) can safely improve recovery of speech and language abilities, gait , and mood in people with Parkinson's disease and related…
- Trial name
- NCT02104401
- Testing
- tDCS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Georgetown University
Chronic Migraine
Cathodal tDCS in Chronic Migraine: Neurophysiological Study and Pilot Therapeutic Trial
Cathodal tDCS decreases the excitability of the cerebral cortex and its daily application during intercritical phase, may have a therapeutic effect in chronic migraine.
- Trial name
- CATCHROMIG (NCT02122237)
- Testing
- Cefaly tDCS
- Where
- Belgium
- Volunteers
- 14 people
- Sponsor
- University of Liege
Major Depressive Disorder, Anxiety
Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious Depression
This is an add-on study to an existing multimodal neuroimaging study in MDD by investigating the acute effects of DLPFC tDCS on threat vigilance in 24-44 patients with MDD, as part of an open-label treatment intervention study.
- Trial name
- NCT03999736
- Testing
- transcranial direct current stimulation using a Soterix mini-CT device
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Mclean Hospital
Pelvic Pain, Healthy
Transcranial Direct Stimulation in Chronic Pelvic Pain
The purpose of this study is to determine whether transcranial direct current stimulation (tDCS) is effective in reducing pain in subjects with chronic pelvic pain.
- Trial name
- NCT01143636
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Alzheimer Disease, Dementia, Mixed
Targeting Brain Physiology to Treat Neuropsychiatric Symptoms of Dementia Using TMS-EEG and tDCS
Agitation and aggression impose a tremendous burden on the individuals living with dementia, their families, caregivers, and healthcare systems.
- Conditions
- Alzheimer Disease, Dementia, Mixed, Dementia, Behavior Problem
- Trial name
- tTED (NCT03846492)
- Testing
- Transcranial Direct Current Stimulation (tDCS)
- Where
- Canada
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
Primary Progressive Aphasia, Logopenic Progressive Aphasia
Transcranial Direct Current Stimulation in the Treatment of Primary Progressive Aphasia
While many have strongly suggested that transcranial direct current stimulation (tDCS) may represent a beneficial intervention for patients with primary progressive aphasia (PPA), this promising technology has not yet been…
- Conditions
- Primary Progressive Aphasia, Logopenic Progressive Aphasia, Non-Fluent Primary Progressive Aphasia
- Trial name
- NCT05386394
- Testing
- Active tDCS + Language Therapy
- Where
- 3 sites in United States, Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Schizophrenia
Transcranial Direct Current Stimulation Influences on Cognitive Inhibition in Schizophrenia
A deficit in cognitive suppression is a trait of patients with schizophrenia. Cognitive suppression is the ability to control or suppress irrelevant responses and to adopt relevant responses instead.
- Trial name
- NCT01971073
- Testing
- transcranial direct current stimulation
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
Insulin Resistance, Obesity
Enhancing Brain Health by TDCS in Persons with Overweight and Obesity
Disturbances in the hypothalamus communication pathways with other regions in the brain and the periphery may represent a potential link between metabolic and cognitive health.
- Conditions
- Insulin Resistance, Obesity, Diabetes Type 2
- Trial name
- STIM (NCT05228067)
- Testing
- anodal transcranial direct current stimulation, cathodal transcranial direct current stimulation
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Chronic Stroke
Brain Stimulation and Robotics in Chronic Stroke Motor Recovery
Motor skill training and transcranial direct current stimulation (tDCS) have separately been shown to alter cortical excitability and enhance motor function in humans.
- Trial name
- NCT03562663
- Testing
- Transcranial direct current stimulation, Upper extremity robotics
- Volunteers
- 82 people
- Sponsor
- Burke Medical Research Institute
ASD
Neuroregulatory Effect and Mechanism of tDCS on Medial Prefrontal Cortex in ASD
In this proposed study, a transcranial direct current stimulator is used to intervene in the medial prefrontal cortex of children with autism, and the efficacy of this intervention method is evaluated, as well as the internal…
- Trial name
- NCT06305988
- Testing
- Transcranial direct current stimulation
- Where
- China
- Volunteers
- 36 people
- Sponsor
- Jian-Jun Ou
Epilepsy, Seizures
Closed-loop System Using Transcranial Direct Current Stimulation (tDCS) for Epilepsy
In this pilot study, the researchers investigated the feasibility of a closed-loop electroencephalography (EEG) / transcranial direct current stimulation (tDCS) system for treatment of epilepsy.
- Trial name
- NCT01415362
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Spaulding Rehabilitation Hospital
Accidental Falls, Aging
tDCS in Elderly Fallers Study
The objective of this study is to determine if a four-week, 20-session intervention of transcranial direct current stimulation (tDCS), as compared to sham intervention, improves dual task standing and walking performance (Aim 1)…
- Trial name
- NCT03814304
- Testing
- tDCS
- Where
- United States
- Volunteers
- 99 people
- Sponsor
- Hebrew SeniorLife
Depression, Anxiety
Modulating Default Mode Network Function: A Transcranial Direct Current Stimulation (TDCS) Pilot Study
The primary purpose of this research is to gather scientific information about how different people's brains work when they look at different types of pictures.
- Trial name
- MDMN (NCT04598152)
- Testing
- TDCS - transcranial direct current stimulation
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Jay Fournier
Stroke
Improving Measurement and Treatment of Post-stroke Neglect
This study examines how to best assess and treat post-stroke neglect. This study will examine the preliminary effects of an innovative intervention (repetitive task-specific practice + transcranial direct current stimulation) for…
- Trial name
- NCT03317860
- Testing
- Active direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- VA Office of Research and Development
Healthy
Effects of tDCS Over the Cerebellum on Motor Function
This study will evaluate whether applying electrical stimulation on the cerebellum (posterior and lower part of the brain) can influence brain excitability and hand movement performance.
- Trial name
- NCT00413842
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Incomplete Spinal Cord Injury
A Telerehabilitation Program for SCI
This study evaluates a remotely supervised, home-based therapeutic program to improve upper-limb voluntary movement in adults with tetraplegia caused by incomplete spinal cord injury (iSCI).
- Trial name
- NCT04977037
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- The University of Texas Health Science Center, Houston
Stroke, Upper Extremity Dysfunction
Dual Channel Rehabilitation Technology Promotes Rapid Recovery of Upper Limbs After Stroke
The injury and remodeling mechanism about upper extremity motor network after stroke is not clear. There are few studies on the motor network covering cortex, white matter and blood perfusion at the time.
- Conditions
- Stroke, Upper Extremity Dysfunction, Transcranial Direct Current Stimulation, Image, Body
- Trial name
- NCT04944680
- Testing
- Transcranial Direct Current Stimulation therapy, Motor imagery therapy, Transcranial Direct Current Stimulation and motor imagery therapy
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Fu Xing Hospital, Capital Medical University