Clinical trials: Transcranial Direct Current Stimulation
Chronic Schizophrenia
The Effect of Transcranial Direct Current Stimulation on Human Brains: A Neuroimaging Study
The purpose of this project is to examine brain function before, during, and after the administration of tDCS (Transcranial Direct Current Stimulation). The brain can perform its job well or poorly depending on many things.
- Trial name
- NCT02421146
- Testing
- Transcranial direct current stimulation
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Chronic Pain, Osteoarthritis
Effects of tDCS and tUS on Pain Perception in OA of the Knee
The purpose of this study is to investigate the effects of transcranial direct current stimulation (tDCS) in conjunction with transcranial ultrasound (TUS) on pain perception and functional limitations in people with…
- Trial name
- NCT02723929
- Testing
- active low-intensity transcranial electrical stimulation/active transcranial ultrasound
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Spaulding Rehabilitation Hospital
Schizophrenia
The Effects of tDCS on the Neuronal Mechanisms of Cognitive Control in Schizophrenia
The purpose of this study is to better understand the neural correlates of cognitive control (CC) deficits in schizophrenia and determine how these mechanisms can be modulated by transcranial direct current stimulation (tDCS).
- Trial name
- NCT03077347
- Testing
- Transcranial Direct Current Stimulation
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Healthy
4 mA tDCS, Estrogen, and Leg Muscle Fatigability
The majority of transcranial direct current stimulation (tDCS) studies have failed to consider sex as a modulating factor. This neglect may partly account for the high inter-subject variability bemoaned by many tDCS investigators…
- Trial name
- NCT04471805
- Testing
- Transcranial direct current stimulation 4 mA
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Aphasia, Non-fluent Aphasia
Combining tDCS and CILT in Non-fluent Aphasia
The long-term goal of this work is to determine if combining a highly intensive, task-specific behavioral language intervention with modulation of the efferent cerebellar-cortical pathway using transcranial direct current…
- Conditions
- Aphasia, Non-fluent Aphasia, Stroke, Brain Injuries
- Trial name
- NCT05561400
- Testing
- tDCS
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Minnesota
Mild Cognitive Impairment, Alzheimer's Disease
Enhancing Spatial Navigation Using Non-Invasive Brain Stimulation
Remembering how to travel from one location to another is critical in everyday life, yet this vital ability declines with normal aging and can be further affected by conditions that disproportionately affect the elderly, such as…
- Trial name
- NCT01958437
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Reflex Sympathetic Dystrophy
Investigation of the Efficacy of tDCS in the Treatment of Complex Regional Pain Syndrome (CRPS) Type 1
The efficacy of the current standard non-pharmacological treatments for complex regional pain syndrome (CRPS), a painful syndrome mostly occurring after musculoskeletal trauma, is suboptimal.
- Trial name
- NCT01960400
- Testing
- Graded motor imagery (GMI)
- Where
- Canada
- Volunteers
- 22 people
- Sponsor
- Université de Sherbrooke
Stroke
Optimizing Current and Electrode Montage for Transcranial Direct Current Stimulation in Stroke Patients
The purpose of this study is to determine the optimal transcranial direct current stimulation (tDCS) amplitude and electrode montage that is both safe and efficacious
- Trial name
- COBRE_JIpro3 (NCT02763826)
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Medical University of South Carolina
Schizophrenia, Bipolar Disorder
Restoration of Cognitive Function With TDCS and Training in Serious Mental Illness
Development of interventions that can effectively target and remediate the cognitive and functional impairment associated with serious mental illness is a treatment priority.
- Conditions
- Schizophrenia, Bipolar Disorder, Schizo Affective Disorder
- Trial name
- NCT03208036
- Testing
- TDCS, Cognitive Remediation, Bridging Group
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- VA Office of Research and Development
Stroke, Aphasia
Evaluating Anodal tDCS Preceding Aphasia Therapy
The purpose of this study is to determine if non-invasive brain stimulation (transcranial direct current stimulation) delivered prior to language therapy will improve word-finding in individuals with aphasia who are 6 months or…
- Trial name
- NCT02249819
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Northwell Health
Major Depressive Disorder
Intensive tDCS for MDD: Feasibility Study
This will be a prospective, open-label, single-arm study to determine the safety and feasibility of an intensive treatment of transcranial direct current stimulation (tDCS) for major depressive disorder (MDD).
- Trial name
- tDCSintensif (NCT05194267)
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Knee Osteoarthritis, Chronic Pain
Self Transcranial Direct Current Stimulation for Pain in Older Adults With Knee Osteoarthritis
The purpose of this study is to determine the feasibility and preliminary efficacy of two weeks of self Transcranial Direct Current Stimulation (tDCS) for pain in older patients with knee osteoarthritis (OA).
- Trial name
- NCT03425019
- Testing
- Soterix 1x1 tDCS mini-CT Stimulator device
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- The University of Texas Health Science Center, Houston
Social Anxiety
Augmenting Exposure Therapy for Social Anxiety With Transcranial Direct Current Stimulation
This study will examine whether transcranial direct current stimulation (tDCS) can be used to improve outcomes from exposure therapy for social anxiety disorder, and facilitate extinction of fear responding toward individuals…
- Trial name
- NCT03743571
- Testing
- transcranial direct current stimulation, exposure therapy
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Nevada, Reno
Schizophrenia, Schizoaffective Disorder
Remediation of Auditory Recognition in Schizophrenia With tDCS
The purpose of this study is to determine whether transcranial direct current stimulation (tDCS), when combined with different forms of computer based training, improves the ability to discriminate small differences between…
- Trial name
- NCT02869334
- Testing
- Active Transcranial direct current stimulation (tDCS), Auditory Remediation, Control computer activities
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- New York State Psychiatric Institute
Stroke
Targeted High-definition Transcranial Direct Current Stimulation (HD-tDCS) for Reducing Post-stroke Movement Impairments
Stroke is the leading cause of serious, long-term disability. The emergence of abnormal muscle synergies following a stroke presents a major limitation to the recovery of independent function.
- Trial name
- NCT05174949
- Testing
- Transcranial direct current stimulation (high-definition)
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- University of Oklahoma
Opioid Dependence, Craving
tDCS to Decrease Opioid Relapse (UG3)
In the current proposal, the investigators will measure behavioral and brain responses following transcranial direct current stimulation (tDCS) to the dorsolateral prefrontal cortex (DLPFC) (anode on right DLPFC, cathode on the…
- Trial name
- NCT03842137
- Testing
- tDCS
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Butler Hospital
Brain Infarction, Brain Ischemia
Transcranial Direct Current Stimulation, Improve Functional Motor Recovery, Affected Arm
Overall goal of this study is to determine if transcranial direct current stimulation (tDCS) plus conventional occupational therapy improves functional motor recovery in the affected arm-hand in patients after an acute ischemic…
- Trial name
- NCT01201629
- Testing
- t DC stimulation, tDCStimulation
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Oklahoma
Stuttering, Developmental
Non-invasive Brain Stimulation in Adults Who Stutter
Research studies in stuttering have shown that activity patterns in certain brain areas differ in people who stutter compared to people who do not stutter when speaking.
- Trial name
- NCT03437512
- Testing
- Anodal tDCS, Fluency training
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- University of Michigan
Multiple Sclerosis
tDCS and Glucose Uptake in Leg Muscles
This study is to examine the efficacy of tDCS to improving walking in people with Multiple Sclerosis (PwMS). Our study compromises 1 group of subjects with MS which will attend the lab for three sessions.
- Trial name
- NCT04016844
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Iowa
Stroke, Fatigue
Post-stroke Fatigue, Inflammation, tDCS
Fatigue is a common condition after an individual has a stroke. While the negative impacts of post-stroke fatigue are well known, the knowledge of the causes of post-stroke fatigue and effective treatments for post-stroke fatigue…
- Conditions
- Stroke, Fatigue, Chronic Stroke, Stroke Sequelae
- Trial name
- NCT05330988
- Testing
- anodal transcranial direct current stimulation (a-tDCS)
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Medical University of South Carolina