Clinical trials: Transcranial Alternating Current Stimulation
Alzheimer Disease
Effect of Modulating Gamma Oscillations Using tACS
This study aims to implement an intervention based on multiple, individualized multifocal tACS stimulation sessions based on individual PET and MRI information in patients with amyloid-positive PET with the hope that this leads…
- Trial name
- NCT03412604
- Testing
- Transcranial Alternating Current Stimulation (tACS)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Massachusetts General Hospital
Bipolar Disorder, Bipolar and Related Disorders
Targeted Alternating Current and Cognitive Training Intervention for Cognitive Control in Bipolar Disorders
This study is testing whether a type of gentle brain stimulation, combined with computer-based brain training exercises, can help improve thinking skills in Veterans with bipolar disorder.
- Conditions
- Bipolar Disorder, Bipolar and Related Disorders, Veterans, Suicide
- Trial name
- TACTIC-BD (NCT07845409)
- Testing
- Soterix 1x1 tES mini-CT
- Where
- United States
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Working Memory
Modulation of Brain Oscillations Underlying Working Memory
This study will use novel transcranial alternating current stimulation (tACS) protocols and electroencephalography (EEG) to modulate and measure brain oscillations that underlie working memory.
- Trial name
- NCT05923606
- Testing
- Active tACS
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Adults With Variability in Their Mood
Restorative Neurophysiology: Backing up and Restoring the Brain (BandR)
Study to examine the extent to which neurophysiological states recorded for a specific person on one day can be induced on a subsequent day
- Trial name
- BandR (NCT07252011)
- Testing
- Transcranial alternating current stimulation (tACS), Neuro/biofeedback, Recall
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Disorders of Consciousness
Intervention Effect of Transcranial Alternating Current Stimulation (tACS) on Disorder of Consciousness (DOC)
To investigate the effect of high definition-transcranial alternating current stimulation(HD-tACS) on consciousness promotion in patients with chronic consciousness disorders and the underlying neural mechanism by EEG.
- Trial name
- NCT06076733
- Testing
- high definition-transcranial alternating current stimulation
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Anhui Medical University
Alcohol Use Disorder
A Pilot Study of Non-invasive Brain Stimulation to Boost the Efficacy of Psychotherapy in a Community Sample of People Who Drink Alcohol
The goal of this small (n=75) proof-of-concept randomized clinical trial is to test the effects of transcranial alternating current stimulation (tACS) during motivational interviewing (MI) sessions with participants who drink at…
- Trial name
- tACS-MI (NCT04770025)
- Testing
- High-density transcranial alternating current stimulation, Motivational interviewing
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- The Mind Research Network
Generalized Anxiety Disorder (GAD), Chronic Insomnia
Transcranial Alternating Current Stimulation for Generalized Anxiety Disorder and Insomnia: An Open-Label Pilot Study
This is an open-label pilot clinical trial to evaluate the effects of transcranial alternating current stimulation (tACS) in adults diagnosed with generalized anxiety disorder (GAD) and chronic primary insomnia.
- Trial name
- NewWaves (NCT07429578)
- Testing
- Transcranial Alternating Current Stimulation (tACS)
- Where
- Brazil
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo
Cannabis Use Disorder
Applying Neuromodulation to Boost the Efficacy of Motivational Interviewing
The goal of this clinical trial is to learn how adding brain stimulation to a brief counseling session affects adults with cannabis use disorder.
- Trial name
- NCT07787572
- Testing
- transcranial alternating current stimulation, Motivational interviewing (MI)
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- The Mind Research Network
Deep Brain Stimulation, Parkinson's Disease (PD)
Testing of an Interface for Synchronizing tACS-DBS With a Phase-locked-loop
The investigators aim to test an interface to phase-lock transcranial alternating current stimulation (tACS) and deep brain stimulation (DBS) for future studies investigating the effects of different time-lags between DBS and…
- Trial name
- NCT07139093
- Testing
- DBS-coupled tACS
- Where
- Germany
- Volunteers
- 2 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Amphetamine-Related Disorders
Treatment Effect of Cross-frequency Transcranial Alternating Current Stimulation on the MUD
The purpose of this research is to evaluate the efficacy of multiple sessions of theta-gamma cross-frequency transcranial alternating current stimulation in patients with methamphetamine (MA) use disorders.
- Trial name
- NCT06145698
- Testing
- Cross-frequency transcranial alternating current stimulation via the Neuroelectrics Starstim 32 transcranial electric stimulation device
- Where
- China
- Volunteers
- 32 people
- Sponsor
- Shanghai Mental Health Center
Schizophrenia, Schizoaffective Disorder
Theta tACS During Working Memory Training: A Pilot Study of the Effects on Negative Symptoms of Schizophrenia
In this randomized double-blind trial, we investigated whether externally induced left-hemispheric frontoparietal theta synchronization by multi-electrode online theta (6Hz) transcranial alternating current stimulation (tACS)…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Negative Symptoms, Working Memory Training
- Trial name
- NCT04545294
- Testing
- Theta tACS
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Stroke, Upper Limb Function
Investigating the Effects of Transcranial Stimulation to Advance Stroke Rehabilitation
Non-invasive brain stimulation (NIBS) has the potential to boost rehabilitation after stroke by creating a 'pro-plastic' environment, where the brain is more adaptable in response to movement (motor) training.
- Trial name
- T-STAR (NCT06842095)
- Testing
- Transcranial Alternating Current Stimulation (beta-tACS)
- Where
- United Kingdom
- Volunteers
- 60 people
- Sponsor
- University of Oxford
Mild Cognitive Impairment
Effects of tACS Combined With CCT for Patients With MCI
This goal of this study is to explore the effects of transcranial alternating current stimulation(tACS) combined with computerized cognitive training(CCT) on improving cognition for patients with mild cognitive impairment(MCI).
- Trial name
- NCT04135742
- Testing
- Transcranial Alternating Current Stimulation, Cognitive Training
- Where
- 2 sites in China
- Volunteers
- 195 people
- Sponsor
- Shanghai Mental Health Center
Delirium
Transcranial Alternating Current Stimulation on Patients with Delirium and Critical Illness (DeliTACS)
The goal of this clinical trial is to learn if transcranial alternating current stimulation can shorten the duration of delirium in intensive care setting.
- Trial name
- DeliTACS (NCT06460363)
- Testing
- Transcranial alternating current stimulation (TACS)
- Where
- Finland
- Volunteers
- 78 people
- Sponsor
- Kuopio University Hospital
Lewy Body Dementia (LBD), Transcranial Alternating Current Stimulation
Transcranial Alternating Current Stimulation in Lewy Body Dementia
The aim of the study is to evaluate the safety, feasibility, clinical and biological efficacy, and predictors of efficacy of an intervention consisting of transcranial alternating current stimulation (tACS) in patients with Lewy…
- Trial name
- TACSDLB2 (NCT07375771)
- Testing
- Transcranial Alternating Current Stimulation
- Where
- 2 sites in Italy
- Volunteers
- 40 people
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Autism Spectrum Disorder
The Validation and Biological Index Studies on the Improved Social Function of ASD by 40 Hz tACS
In this proposed study, tACS will be used to intervene in the autism spectrum disorders of children and adolescents, and the efficacy of this intervention method will be evaluated, as well as the internal mechanism of…
- Trial name
- NCT06362200
- Testing
- 40 Hz tACS intervention
- Where
- China
- Volunteers
- 47 people
- Sponsor
- Central South University
Schizophrenia / Schizoaffective Disorder
tACS for Self-Other Boundary in Schizophrenia
This clinical trial investigates whether a non-invasive brain stimulation technique called transcranial alternating current stimulation (tACS) can improve the ability to distinguish between "self" and "others" in patients with…
- Trial name
- NCT07818668
- Testing
- Transcranial Alternating Current Stimulation (tACS)
- Where
- China
- Volunteers
- 100 people
- Sponsor
- Chunyan Zhu
Schizophrenia With Auditory Hallucinations
Frequency- and Intensity-Dependent After-Effects of High-Definition Transcranial Alternating Current Stimulation on Resting-State Electroencephalography
This study aims to investigate the after-effects of high-definition transcranial alternating current stimulation (HD-tACS) with varying parameters on resting-state brain activity in patients with schizophrenia experiencing…
- Trial name
- NCT07798804
- Testing
- high-definition transcranial alternating current stimulation(HD-tACS)
- Where
- China
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Schizophrenia
Efficacy of tACS for Treatment of Auditory Hallucinations in Refractory Schizophrenia
The aim of this study is to evaluate the feasibility and efficacy of transcranial alternating current stimulation (tACS) as an add-on treatment for auditory hallucinations in refractory schizophrenia.
- Trial name
- NCT05282329
- Testing
- Transcranial alternating Current Stimulation (tACS)-active
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Tianjin Anding Hospital
Seizures
Boosting The Intervention Effect of Negative Memory Through tACS Stimulation
The objectives of this study include: 1) investigating the impact of negative memory substitution on an individual's other intellectual memories (i.e., neutral memories) and the underlying neurocognitive mechanisms; 2)…
- Trial name
- NCT06375395
- Testing
- Active tACS Device
- Volunteers
- 60 people
- Sponsor
- Xuanwu Hospital, Beijing