Clinical trials: Transanal Endoscopic Surgery, open to volunteers
Rectal Neoplasms
Endoscopic Submucosal Dissection vs. Transanal Endoscopic Surgery for Rectal Neoplasia
This prospective observational cohort study aims to compare the clinical and procedural outcomes of Endoscopic Submucosal Dissection (ESD) and Transanal Minimally Invasive Surgery (TAMIS) for the treatment of early-stage rectal…
- Trial name
- ESTER (NCT06902701)
- Testing
- Endoscopic Submucosal Dissection (ESD), Transanal Endoscopic Surgery (TES)
- Where
- 5 sites in Turkey (Türkiye)
- Volunteers
- 156 people
- Sponsor
- Turkish Society of Colon and Rectal Surgery
Rectal Cancer Stage I
Preoperative Chemoradiotherapy and Transanal Endoscopic Microsurgery Versus Ttransanal Endoscopic Microsurgery in T1 N0, M0 Rectal Cancer (TAUTEM-T1 Study)
Introduction: The standard treatment for rectal adenocarcinoma is total mesorectal excision (TME), a technique involving resection of the rectum, with or without a temporary or permanent stoma.
- Trial name
- TAUTEM-T1 (NCT06450574)
- Testing
- Capecitabine (Xeloda), 50.4 Gy, Transanal Endoscopic Microsurgery (TEM)
- Volunteers
- 106 people
- Sponsor
- Corporacion Parc Tauli
Rectal Cancer, Colo-rectal Cancer
Pre-therapeutic MRI Assessment of Early-Stage Rectal Cancer and Significant Rectal Polyps to Avoid Major Resectional Surgery
When a patient is diagnosed with a rectal (bowel) polyp or cancer, radiology doctors read MRI scans to describe how deeply the cancer invades into the bowel wall (this is the 'stage' of the cancer).
- Trial name
- PRESERVE (NCT04103372)
- Testing
- MRI scan, Radiologist training
- Where
- 23 sites in United Kingdom
- Volunteers
- 200 people
- Sponsor
- Imperial College London
Rectal Cancer Stage I
Endoscopic (EID) Versus Surgical (TAMIS) Local Excision for Early Stage Rectal Cancer
In this clinical trial, we compare the endoscopic technique, endoscopic intermuscular dissection (EID), with the surgical technique, transanal minimally invasive surgery (TAMIS) for the treatment of early stage rectal cancer.
- Trial name
- ENSURE (NCT07846046)
- Testing
- Endoscopic Intermuscular Dissection (EID), Transanal Minimally Invasive Surgery (TAMIS)
- Where
- 19 sites in Netherlands
- Volunteers
- 246 people
- Sponsor
- Amsterdam UMC, location VUmc
Colorectal Neoplasms, Surgery
TES RCT Fleet Enema vs Oral Mechanical Bowel Prep
There is no consensus about the best bowel preparation prior to transanal endoscopic surgery TES). Cleanliness and visibility in the rectosigmoid and rectum are of utmost importance, possibly even more so than during colonoscopy…
- Trial name
- TESEO (NCT05148494)
- Testing
- Fleet Enema, Pico-Salax
- Where
- Canada
- Volunteers
- 66 people
- Sponsor
- Nova Scotia Health Authority
Rectal Cancer, Rectal Adenocarcinoma
SCARLET - Italian proSpeCtionAl obseRvationaL multicEntre Study on Treatment for recTal pT1 Cancer
The purpose of this prospective, observational, multicenter study is to evaluate the impact of adjuvant radiotherapy or chemoradiotherapy on disease-free survival (DFS) in patients with pathological T1 (pT1) rectal cancer…
- Conditions
- Rectal Cancer, Rectal Adenocarcinoma, Rectal Cancer Patients, Rectal Cancer, Radiotherapy
- Trial name
- SCARLET (NCT07695519)
- Where
- Italy
- Volunteers
- 196 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS