Clinical trials: Tranexamic Acid Use
Knee Arthroplasty, Total, Knee Arthritis, Osteoarthritis
The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty Surgery
The aim of this clinical trial is to evaluate the effect of administering low-dose epinephrine and tranexamic acid on perioperative blood loss, thromboembolic complications, and hospitalization duration in patients undergoing…
- Conditions
- Knee Arthroplasty, Total, Knee Arthritis, Osteoarthritis, Total Knee Anthroplasty, Blood Loss
- Trial name
- NCT07089251
- Testing
- low-dose epinephrine and tranexamic acid, Tranexamic Acid (TXA) treatment
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- King Abdullah International Medical Research Center
Skin Neoplasms
Use of Tranexamic Acid in Reduction of Post-Op Complications in Mohs Micrographic Surgery
The purpose of this study is to evaluate the use of locally injected tranexamic acid (TXA) under the skin during Mohs micrographic surgery for removal of skin cancers in patients on anticoagulation.
- Trial name
- NCT04630886
- Testing
- Tranexamic acid injection, Lidocaine Epinephrine
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Riley McLean
Metastasis Spinal Tumor
Tranexamic Acid Use for Bleeding Prevention in the Surgical Treatment of Metastatic Spinal Tumor in Lung Cancer Patients
Massive blood loss occurs in metastatic spinal tumor resection and may cause severe complications. The objective of this study is to investigate whether the use of tranexamic acid will reduce perioperative and postoperative…
- Trial name
- NCT06023212
- Testing
- Tranexamic Acid, stroke-physiological saline solution (SPSS)
- Where
- China
- Volunteers
- 150 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Hemorrhage/Blood Loss During Myomectomies, Fibroids
Use of Intravenous Tranexamic Acid During Myomectomy
The purpose of this study is to determine the effect of the early administration of intravenous (IV) Tranexamic acid (TA) on perioperative bleeding (as defined by measured intraoperative estimated blood loss (EBL), change in pre…
- Trial name
- TA (NCT02620748)
- Testing
- Tranexamic Acid, Saline Solution
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- George Washington University
Fracture of Femur
Tranexamic Acid in Chinese Elderly Patients With Intertrochanteric Fracture RCT
Hip fracture posed a major challenge to the health care system, with the one-year mortality of hip fracture reported as being approximately 20%.
- Trial name
- NCT04290884
- Testing
- Tranexamic Acid
- Where
- Hong Kong
- Volunteers
- 120 people
- Sponsor
- The University of Hong Kong
Postoperative Hematoma, Postoperative Seroma
Investigating the Use of Intravenous Tranexamic Acid in Gender Affirming Mastectomy
Gender affirming surgeries (GAS) have been steadily increasing in the US, with the gender affirming mastectomy (GAM) being the most common surgery performed.
- Trial name
- IVTXA (NCT05794321)
- Testing
- Intravenous TXA
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Hematoma Postoperative, Venous Thromboembolism
Use of Tranexamic Acid in Reduction Mammoplasty
Breast reduction mammoplasty (BRM) is among the most commonly performed procedures in plastic surgery. However, postoperative hematoma is one of the most common complications following BRM.
- Trial name
- TREX-ARM (NCT04947514)
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Burns, Skin Graft Complications
Burn Study- Tranexamic Acid Versus Thrombin in Split Thickness Skin Graft
Investigators hypothesize that topical tranexamic acid will have better or comparable efficacy to topical thrombin in reducing hematoma formation at the wound base.
- Trial name
- NCT06379724
- Testing
- Tranexamic acid, Thrombin JMI, skin graft
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- University of Kansas Medical Center
Placenta Previa
Tranexamic Acid Use in Elective Cesarean Section for Women With Placenta Previa
Tranexamic Acid Use in Elective Cesarean Section for Women With Placenta Previa
- Trial name
- NCT03060889
- Testing
- Tranexamic acid
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Haemorrhage, Bariatric Surgery Candidate
the Use of Tranexamic Acid to Prevent the Bleeding in Bariatric Surgery
Our study aims at evaluating the role of tranexamic acid in bariatric surgery since, The effect of conservative therapy using tranexamic acid for postoperative hemorrhage after bariatric surgery is still very much a novel…
- Trial name
- NCT07187258
- Testing
- tranexamic acid (1 g diluted in 100 mL of 0.9% saline
- Where
- Egypt
- Volunteers
- 132 people
- Sponsor
- Cairo University
Episiotomy Wound, Anemia
Use of Tranexamic Acid After Vaginal Delivery with Episiotomy a RCT Placebo Control Trail
The objective of this study is to assess the effect of TA treatment on decline in Hb levels following vaginal delivery with an episiotomy, compared to a control group not receiving TA.
- Conditions
- Episiotomy Wound, Anemia, Early Postpartum Hemorrhage, Hemoglobin
- Trial name
- NCT05448456
- Testing
- Tranexamic acid
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Assuta Ashdod Hospital
Intraoperative Blood Loss, Pediatric
Tranexamic Acid in Pediatric Undergoing Proximal Femoral Osteotomies and/or Acetabular Osteotomy
Surgical hip reconstruction reduces the hip joint through soft tissue releases and osteotomies of the femur and/or pelvis. Blood loss and subsequent blood transfusion are normal consequences of hip reconstruction.
- Conditions
- Intraoperative Blood Loss, Pediatric, Orthopedic Disorder
- Trial name
- NCT04811313
- Testing
- Tranexamic acid, caudal epidural block
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Assiut University
Pelvic Mass
Tranexamic Acid in Reducing Blood Loss in Patients With Pelvic Tumors Undergoing Hemipelvectomy Surgery
This early phase I trial studies how well tranexamic acid works in reducing the loss of blood in patients with pelvic tumors undergoing hemipelvectomy surgery.
- Trial name
- NCT03128866
- Testing
- Hemipelvectomy, Tranexamic Acid
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- M.D. Anderson Cancer Center
Post Partum Hemorrhage
Use of TXA to Prevent Postpartum Hemorrhage
Postpartum hemorrhage (PPH) occurs in up to one in ten deliveries worldwide and is the leading cause of maternal morbidity and mortality.
- Trial name
- TAPPH-1 (NCT03069859)
- Testing
- TXA (1g)
- Where
- Canada
- Volunteers
- 31 people
- Sponsor
- Sunnybrook Health Sciences Centre