Clinical trials: Tracheostomy Patients
Tracheostomy, Mechanical Ventilation
Speech Effects of a Speaking Valve Versus External Positive End-expiratory Pressure (PEEP) in Tracheostomized Ventilator-Dependent Neuromuscular Patients
Background: Many patients with respiratory failure related to neuromuscular disease receive chronic invasive ventilation through a tracheostomy.
- Trial name
- NCT00978783
- Testing
- Passy Muir Valve, Positive end expiratory pressure
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University of Versailles
Tracheostomy
Cough Flow as a Criterion Decannulation Threshold in Prolonged Tracheostomy Patients
Background: International studies have proposed a cough peak flow (CPF) of ≥160 L/min as a reference threshold for safe decannulation.
- Trial name
- NCT07317791
- Testing
- standardized tracheostomy decannulation protocol
- Where
- 5 sites in China
- Volunteers
- 500 people
- Sponsor
- Hongying Jiang, MD
Prolonged Weaning
Impact of the Nature and Interface of the Tracheostomy Cannula on Dyspnea in Patients Weaning From Artificial Ventilation in Weaning Unit
This trial aims to assess dyspnea intensity in tracheostomized patients undergoing prolonged artificial ventilation weaning. The primary outcome is dyspnea measured by the Visual Analogue Scale (VAS-Dyspnea).
- Trial name
- DYSTRACH (NCT06185998)
- Testing
- low pressure tracheostomy cannulas, plated balloon tracheostomy cannulas
- Volunteers
- 76 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Mechanical Ventilator Weaning
Assessment of Cough Strength in Patients With Tracheostomies
The investigators propose to assess cough strength in patients undergoing spontaneous breathing trials in the Intermediate Intensive Care Unit (IICU) and compare their cough strength under two conditions, 1.
- Trial name
- NCT02566512
- Testing
- Tracheostomy cuff inflation., Tracheostomy cuff deflation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University of Manitoba
Other Tracheostomy Complication
LipoAerosol© Inhalation After Tracheostomy
Patients after tracheostomy represent a substantial part in the ear nose throat clinic. Long-term intubated patients in intensive care units also profit from tracheostomy due to an improved respiratory toilet.
- Trial name
- NCT02157129
- Testing
- LipoAerosol© inhalation, Physiologic saline inhalation
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- Technical University of Munich
Tracheostomy, Characteristics Disease
Early SARS-CoV-2 Tracheostomy
Objective of this case series was to evaluate the characteristics of early COVID-19 tracheostomy and its effect on laboratory parameters.
- Conditions
- Tracheostomy, Characteristics Disease, Metabolic Disturbance
- Trial name
- NCT05520957
- Testing
- Tracheostomy
- Where
- Bosnia and Herzegovina
- Volunteers
- 17 people
- Sponsor
- Cantonal Hospital Zenica
Swallowing Disorders, Dysphagia
The Objective is to Respond to Patients' Needs in the Field of Larynx Replacement
Supplement pharyngolaryngeal deficient functions by insertion of a prosthesis with valves in order to allow tracheotomy closing (when applicable) and / or to allow restoration of god swallowing capacity.
- Conditions
- Swallowing Disorders, Dysphagia, Laryngeal Neoplasms
- Trial name
- NCT00576134
- Testing
- Implantation of intralaryngeal prosthesis with a new double valve system, allowing tracheotomy closing
- Where
- France
- Volunteers
- 10 people
- Sponsor
- University Hospital, Strasbourg, France
Pneumonia
Improving Oral Care to Reduce Hospital-Acquired Pneumonia (HAP) in the Acute Neurologically Impaired Adult
Hypothesis: The investigators hypothesize that the current oral protocol is sub-optimal and an enhanced protocol will decrease the incidence of hospital acquired pneumonia (HAP)in the acute, non-intubated, care-dependent…
- Trial name
- NCT01498601
- Testing
- Enhanced oral care protocol
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Fraser Health
Respiratory Failure, Speech
Early Speech With One-Way Speaking Valve in Tracheostomy Patients
Patients with tracheostomy who are on and off of mechanical ventilation initially lose the ability to speak, and the use of one-way speaking valves (OWSV) is one method of restoring speech in these patients.
- Conditions
- Respiratory Failure, Speech, Aphonia
- Trial name
- NCT03008174
- Testing
- Early one-way speaking valve (OWSV) assessment
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Johns Hopkins University
Evaluate the Effect of a Talking Tracheostomy Tube on Quality of Life
Evaluation of a Tracheostomy Tube That Enables Communication
Verbal communication is vital to critically ill mechanically ventilated patient's quality of life (Hess, 2005). Patients who have a tracheostomy tube may be able to communicate using a speaking valve, however, some patients may…
- Trial name
- BLUSA (NCT02018562)
- Testing
- Portex Blueline Ultra Suctionaid Tracheostomy Tube
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Johns Hopkins University
Tracheostomy Complication, Tracheostomy Hemorrhage
Ultrasound-guided Versus Landmark-guided Percutaneous Dilational Tracheostomy in Pediatric Patients
Percutaneous dilatational tracheostomy is one of the most common procedures performed in pediatric intensive care units. The investigators aimed to compare traditional landmark-guided percutaneous dilatational tracheostomy (PDT)…
- Conditions
- Tracheostomy Complication, Tracheostomy Hemorrhage, Airway Trauma, Percutaneous Tracheostomy
- Trial name
- NCT05834972
- Testing
- Ultrasound-guided percutaneous dilatational tracheosyomy
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aksaray University
Tracheostomy Infection
Infection Control Program in Tracheostomized Patients
Healthcare-associated infections are infections that patients acquire during the course of receiving treatment for other conditions within a healthcare setting and are not present at the time of admission.
- Trial name
- NCT05113329
- Volunteers
- 52 people
- Sponsor
- Assiut University
Stroke, Diaphragm Injury
Effect of Body Tilting on Diaphragm Excursion and Thickness in the Stroke Patients With Tracheotomy by Ultrasonography
The purpose of this study was to examine whether if the effect of standing with assistance of the tilt table on diaphragm excursion and thickness in the stroke patients with tracheotomy.
- Conditions
- Stroke, Diaphragm Injury, Tracheostomy
- Trial name
- NCT05041894
- Testing
- tilt table
- Where
- China
- Volunteers
- 41 people
- Sponsor
- Shenzhen Second People's Hospital
Tracheostomy
Speaking Valve Influence on Breathing, Swallowing and Vocal Functions in Patients With Tracheostomy.
Speaking valve seems to have a beneficial influence on breathing and secretion management in certain patients with tracheostomy.
- Trial name
- NCT05482022
- Testing
- Shiley™ phonate speaking valve, control
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Loewenstein Hospital
Tracheostomy Complication
Percutaneous Dilatational Tracheostomy vs. Surgical Tracheostomy in Neurocritically Ill Patients - a Retrospective Study
The aim of the present quality study is to examine the relationship between choice of tracheotomy procedure and complications in a neurocritically ill patient population at a single center.
- Trial name
- NCT06018220
- Where
- Denmark
- Volunteers
- 383 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Tracheostomy, Mechanical Ventilation
Trcheal High-flow for Weaning From Mechanical Ventilation
Multicentre randomized trial to determine whether tracheal high-flow nasal oxygen can improve weaning outcome vs. conventional oxygen therapy in critically ill tracheostomized patients who are hypoxemic.
- Conditions
- Tracheostomy, Mechanical Ventilation, Hypoxemic Respiratory Failure
- Trial name
- TRACFLOW (NCT07714564)
- Testing
- Oxygen therapy
- Where
- Italy
- Volunteers
- 500 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Dysphagia, Oropharyngeal Dysphagia
Incidence of Dysphagia in Intensive Care Patients With Tracheostomy
This study will inform the feasibility of the High Resolution Impedance Manometry (HRIM) system combined with Automated Impedance Manometry (AIM) analysis as a screening tool for dysphagia and aspiration for the intensive care…
- Trial name
- NCT02874352
- Testing
- high resolution impedance manometry with Automated Impedance Manometry analysis
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Tracheostomy
Percutaneous Tracheostomy With COVID-19
Coronavirus disease 2019 (COVID-19) has brought about a requirement of intensive care and mechanical ventilation for a significant portion of patients.
- Trial name
- NCT04447638
- Testing
- Tracheostomy with aerosol box in COVID-19 positive patients
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Çanakkale Onsekiz Mart University
ICU Patients Dependant on Mechanical Ventilation : Safest Mode of Performing Percutaneous Tracheostomy Among ICU Ventilated Unweanable Patients
Percutaneous Dilatational Tracheostomy: Ultra-perc Versus Ciaglia Blue Dolphin
The aim of this study is to compare Ultra-perc single stage dilator technique with Ciaglia Blue Dolphin ballon dilatation technique for intubated unweanable ICU patients with respect to procedure difficulties and complications.
- Trial name
- NCT02754921
- Testing
- percutaneous dilatational tracheostomy using Ultra-Perc, Percutaneous dilatational tracheostomy using Ciaglia Blue Dolphin
- Volunteers
- 60 people
- Sponsor
- Mohamed Sayed Mohamed Abbas
Tracheostomized Patients, Mechanical Ventilation Weaning
High Flow Tracheal Oxygen for Weaning of Tracheostomized Patients
In this pilot randomized controlled trial (RCT), the investigators aim to explore the feasibility of conducting a powered RCT that examines the efficacy and safety of high flow tracheal oxygen (HFTO) in weaning critically ill…
- Conditions
- Tracheostomized Patients, Mechanical Ventilation Weaning, High Flow Oxygen Therapy
- Trial name
- HFTO-WEAN (NCT07559591)
- Testing
- High-flow tracheal oxygen (HFTO), Tracheal Mask (TM)
- Where
- Saudi Arabia
- Volunteers
- 88 people
- Sponsor
- King Faisal Specialist Hospital & Research Center