Clinical trials: Tooth Loss
Tooth Loss, Edentulousness
Soft Tissue Thickness on Submerged and Non Submerged Implants
Changes in the marginal bone level surrounding the implant are the frequently used parameters in assessing the short- and long-term success.
- Trial name
- NCT02842385
- Testing
- Implant
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ege University
Alveolar Bone Loss
A Clinical Investigation to Evaluate the Healing of Tooth Extraction Sites Filled With BioRestore™
The aim of this study was to evaluate by histology and MSCT scans during a 7-month period, the efficacy of a bioactive glass (Inion BioRestore™) placed in human extraction sockets in the maintenance of alveolar ridge.
- Trial name
- NCT01105026
- Testing
- Alveolar Bone Defect Regeneration Following Tooth Extraction
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Trieste
Tooth Loss
Immediate Implant Placement by Drilling Through Roots
This randomized clinical trial compared two techniques for immediate dental implant placement in molar extraction sites. In the intervention group, implant osteotomy preparation was performed through the interradicular bone…
- Trial name
- NCT07827976
- Testing
- Immediate Implant Placement in fresh extraction socket, Interradicular Bone Drilling Before Molar Extraction
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Cairo University
Dental Caries, Inlays
Ceramic Versus Composite in the Treatment of Posterior Teeth by Inlays or Onlays
The main purpose of this trial is to determine which material, between ceramic and composite, is best to manufacture dental inlays and onlays in the treatment of moderate dental substance losses, generally due to dental caries.
- Trial name
- CECOIA (NCT01724827)
- Testing
- ceramic (Empress CAD, Ivoclar Vivadent), composite (Lava Ultimate, 3M Espe)
- Where
- 6 sites in France
- Volunteers
- 355 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Tooth Loss, Bone Loss
Effect of I-Shape Incısıon Technique on Inter-Implant Papilla: A Prospective Randomized Clinical Trial
Regenerating a predictable inter-implant papilla is the most complex and challenging aspect of implant dentistry. The aim of the study was to compare the efficacy of I shaped incision technique and conventional midcrestal…
- Trial name
- NCT02996370
- Testing
- papilla fill index, crestal bone loss, probing depth
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Ege University
Bone Loss, Tooth Movement
The Introduction of a Novel PAOO Technique
The aim of this study is to evaluate in a prospective, randomized, controlled clinical trail the effectiveness of preorthodontic piezotomy combined with a buccal bone augmentation (in other name periodontlly accelerated…
- Trial name
- NCT05264480
- Testing
- Bone augmentation with minimally invasive corticotomy (piezotomy), Bone augmentation without corticotomy
- Where
- Hungary
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Bone Loss
Artificial Intelligence-Enhanced Three-Dimensional Reconstruction of Ridge Deficiencies
n the current study, AI-assisted 3D ridge augmentation of combined vertical and horizontal deficient ridges utilizing allogenic dentin block versus allogenic dentin shell graft will be assessed.
- Trial name
- NCT06693921
- Testing
- AI/guided block graft, AI/guided shell graft
- Where
- 2 sites in Egypt
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
Gingival Recession, Localized, Sensitivity, Tooth
Two Different Graft Harvesting Techniques Applied in Localized Gingival Recessions
The primary purpose of this study is to compare the root coverage rate of the gingival unit-shaped connective tissue graft, obtained by intraoral de-epithelization, with the traditional de-epithelialized free gingival graft in…
- Conditions
- Gingival Recession, Localized, Sensitivity, Tooth, Attachment Loss, Periodontal
- Trial name
- NCT05923294
- Testing
- Coronally advanced flap with connective tissue graft
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Kutahya Health Sciences University
Tooth Loss
A Comparison of Two Socket Sealing Collagen Matrices for Extraction Socket Management
A prospective RCT of intact extractions with delayed implant placement comparing extraction socket management effectiveness and office economics of two collagen matrices.
- Trial name
- NCT03003819
- Testing
- Control Collagen Wound Dressing, Test Collagen Matrix
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- McGuire Institute
Single Tooth Lost, Dental Implant
Immediate and Early Single Dental Implants
The objective of the research project will be to compare immediate and early unitary implants for the rehabilitation of missing teeth in the upper aesthetic region.
- Trial name
- NCT04075383
- Testing
- immediate dental implant, immediate-delayed dental implant
- Where
- Brazil
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Immediate Dental Implant Placement, Connective Tissue Graft
Immediate Implants in Front Teeth With Bone Loss: Regeneration and Temporary Crown in a Randomized Clinical Study
This clinical trial investigates the biological and clinical outcomes of immediate implant placement in aesthetic areas presenting with buccal bone dehiscence.
- Conditions
- Immediate Dental Implant Placement, Connective Tissue Graft, Connective Tissue Graft Harvesting, Soft Tissue Management in Subcrestal Dental Implants
- Trial name
- GBR / RCT (NCT07415486)
- Testing
- immediate implant placement with DBBM-C and connective tissue graft, immediate implant placement with DBBM-C with collagen membrane
- Volunteers
- 24 people
- Sponsor
- Universitat Internacional de Catalunya
Partial Edentulism, Tooth Loss / Rehabilitation
In Vivo Evaluation of the Accuracy of Immediate Screw-Retained Provisional Crowns Fabricated Using Digital Planning and Guided Surgery
This clinical trial aims to evaluate the in vivo accuracy of a fully digital workflow for the immediate placement of a previously fabricated screw-retained provisional crown using digital planning and guided implant surgery.
- Trial name
- NCT07315607
- Testing
- Fully Guided Implant Placement and Immediate Provisionalization
- Where
- Spain
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Tooth Loss
Tooth Loss Rate and Its Associated Factors: a Retrospective Cross-sectional Study With up to 50 Years of Follow-up.
This study will evaluate, in an adult population (n=448) previously diagnosed with gingivitis and/ or periodontitis, the tooth loss rate and its potential associated factors such as diabetes, smoking, bruxism, cardiovascular…
- Trial name
- NCT06578806
- Volunteers
- 448 people
- Sponsor
- Saint-Joseph University
Periodontal Pocket, Periodontal Bone Loss
Using Xenograft Combined With Barrier Membrane to Improve the Formation of Deep Periodontal Pockets
To evaluate the clinical effect of site preservation after third molars extraction by using tooth extraction of third molars with site preservation using bio-oss and bio-guide in preventing the formation of deep periodontal…
- Conditions
- Periodontal Pocket, Periodontal Bone Loss, Impacted Third Molar Tooth
- Trial name
- NCT06318247
- Testing
- site preservation
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Alveolar Bone Loss
Demineralized Whole-tooth vs Demineralized Particulate Dentin Grafts in Alveolar Ridge Preservation
The aim of this trial is to compare whole-tooth vs particulate dentin for their effects in alveolar ridge preservation.
- Trial name
- NCT05336149
- Testing
- Alveolar ridge preservation using whole-tooth dentin graft, Alveolar ridge preservation using particulate dentin graft
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Periodontal Diseases, Tooth Loss
Effect of Periodontal Maintenance Therapy on Tooth Loss in Regular and Irregular Compliant Smokers and Non-Smokers: A Cohort Retrospective Analysis With a Follow-up Up to 40 Years
Periodontal diseases are infections cause by dental plaque (Socransky, 1970). Risk factors are present which modify the course of disease progression.
- Conditions
- Periodontal Diseases, Tooth Loss, Compliance, Smoking
- Trial name
- NCT04938089
- Testing
- Maintenance
- Where
- Lebanon
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Saint-Joseph University
Tooth Loss
Case Series Evaluation of a Short Dental Implant
Following the loss of teeth, the alveolar bone formed in response to the eruption of the teeth is gradually resorbed by the body.
- Trial name
- Short implant (NCT00798031)
- Testing
- A minimum of two but up to three Astra Tech Dental Implant, Fixture Osseospeed will be placed in the posterior upper jaw of 20 eligible subjects., Placement of dental implant, dental implant
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Clark Stanford
Missing Teeth
Clinical Trial of Zirconia and Metal Adhesive Bridges
Adhesive bridges are becoming popular in patients with congenitally missing teeth and these are type of bridges that can be done with only minimal or with no preparation to replace the missing tooth/teeth.
- Trial name
- NCT01347177
- Testing
- Zirconia-based adhesive bridge, Metal-based adhesive bridge
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- Queen Mary University of London
Tooth Loss
Effect of Zirconia Implant Supported PEKK Crowns Versus Lithium Disilicate Crowns on Esthetics
aim of study is to evaluate esthetic and biomechanical outcome of maxillary anterior single-tooth zirconia implant supported PEKK crowns compared to lithium disilicate crowns on PEKK abutments .
- Trial name
- NCT03521024
- Testing
- poly ether ketone ketone, lithium disilicate
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Dental Crowding, Alveolar Bone Loss
Bone Level Changes Using Clear Aligners Compared to Fixed Appliances in Non-Extraction Treatment of Adults
This study compares two common ways of straightening teeth in adults who have mild-to-moderate crowding of the lower front teeth and do not need any teeth removed: clear aligners and traditional fixed braces.
- Conditions
- Dental Crowding, Alveolar Bone Loss, Malocclusion
- Trial name
- NCT07716007
- Testing
- Fixed orthodontic appliance, Clear aligners
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt