Clinical trials: Tooth Extraction
Healthy, Maxillary First Premolar Tooth Extraction
Gingival Crevicular Fluid Characterization During Orthodontic Treatment
During Orthodontic tooth movement, teeth are moved through alveolar bone under applied forces. The applied mechanical loading force must be transferred to the alveolar bone via periodontal ligament (PDL).
- Conditions
- Healthy, Maxillary First Premolar Tooth Extraction, Canine Retraction
- Trial name
- NCT04226469
- Testing
- Tooth movement
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Dental Pain
Evaluation of EXPAREL for Prolonged Postsurgical Analgesia in Subjects Undergoing Third Molar Extraction
This is a Phase 3, randomized, double-blind, placebo-controlled study in subjects scheduled to undergo elective bilateral third molar extraction under local anesthesia.
- Trial name
- NCT02517905
- Testing
- Bupivacaine liposome
- Where
- United States
- Volunteers
- 166 people
- Sponsor
- Pacira Pharmaceuticals, Inc
Healthy Volunteers
Effect of CYP2C9*3 Polymorphism on Ibuprofen in Pakistani Population
The goal of the study was to identify the effect of CYP2C9 gene polymorphism in the Pakistani population. The main question it aims to answer were: to evaluate the effect of this genetic polymorphism on the clinical efficacy of…
- Trial name
- NCT05983042
- Testing
- Ibuprofen 400 mg
- Where
- Pakistan
- Volunteers
- 200 people
- Sponsor
- Riphah International University
Dental Plaque
Ability of Four Toothpastes to Remove Plaque
The aim of this study is to evaluate and compare the plaque removal efficacy of four experimental toothpastes following a single timed brushing.
- Trial name
- NCT03285984
- Testing
- 67% Sodium Bicarbonate with 6 herbs plus 923parts per million (ppm) Sodium Fluoride, 67% Sodium Bicarbonate without herbs plus 923 ppm Sodium Fluoride, 62% Sodium Bicarbonate with 6 herbs and 5% w/w silica plus 923 ppm Sodium
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Post-operative Pain
Ibuprofen/Acetaminophen Versus Nurofen Plus® and Panadeine® Extra Dental Pain Study
The objective is to assess the efficacy and tolerability of a combination of 400 mg ibuprofen plus 1000 mg acetaminophen, 200 mg ibuprofen plus 500 mg acetaminophen compared with Nurofen Plus® and Panadeine® Extra.
- Trial name
- NCT01229449
- Testing
- Ibuprofen/acetaminophen, Ibuprofen/acetaminophen (higher dose), Nurofen Plus®
- Where
- United States
- Volunteers
- 678 people
- Sponsor
- Reckitt Benckiser LLC
Complications of Extraction of Impacted Teeth
Effect of LLLT and Ozone to Reduce Complications After Extraction of Impacted Lower Molar
Many factors cause third molars to stay impacted in the jaws, hence the extraction of impacted wisdom teeth occurs often in dental clinics.
- Trial name
- NCT05922150
- Testing
- low level laser therapy, ozone gel
- Where
- Iraq
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Alveolar Bone Grafting, Bone Regeneration Following Wisdom Teeth Extraction
Autogenous Tooth Bone Graft for Alveolar Socket Preservation
The purpose of this clinical experiment is to assess how well autogenous tooth bone grafting preserves the alveolar socket after surgical tooth extraction.
- Conditions
- Alveolar Bone Grafting, Bone Regeneration Following Wisdom Teeth Extraction, Tooth Extraction Site Healing
- Trial name
- ATBG (NCT07267637)
- Testing
- "Autogenous Tooth Bone Graft"
- Where
- Yemen
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Haifaa Mohammed Al-hussini
Alveolar Bone Resorption, Alveolar Ridge Enlargement
Is Cross-linked Hyaluronic Acid a Biologic Alternative for Alveolar Ridge Preservation?
Even after atraumatic tooth removal and/or immediate implant placement, some reduction of the alveolar ridge dimension is expected.
- Conditions
- Alveolar Bone Resorption, Alveolar Ridge Enlargement, Tooth Extraction, Hyaluronic Acid
- Trial name
- NCT07496437
- Testing
- DBBM + FGG, Hyaluronic acid + collagen sponge + FGG
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Stomatognatic, Tooth Diseases
Oral Specimen and Data Acquisition Study of Subjects Requiring Third Molar Removal
Background: The third molars (wisdom teeth) normally grow in during late adolescence or early adulthood. Many people need or choose to have these teeth removed with oral surgery.
- Conditions
- Stomatognatic, Tooth Diseases, Diseases, Tooth
- Trial name
- NCT01805869
- Where
- United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Tooth Extraction Status Nos, Tooth Fracture
The Assessment of Curcuma Longa Potentials for Soft and Hard Tissue Healing in Fresh
The study will be conducted on 30 patients with split mouth design patients will be divided into curcumin and PRF groups patients will have bilateral tooth extraction one side will receive curcumin/PRF and the other side will be…
- Trial name
- NCT05816707
- Testing
- PRF, Curcuma Longa gel, extraction socket
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Rania Farouk Mohamed Abdulmaguid
Pain During Caries Excavation
Comparison of Intraoperative Pain Perception During Caries Excavation Using Smart Burs and Carisolv to Conventional Diamond Burs
The goal of this randomized controlled trial is to compare the amount of pain experienced during removal of dental caries using Smart burs, Carisolv, and conventional diamond burs in adults aged 18-45 years with active caries in…
- Trial name
- NCT07869407
- Testing
- polymer burs, Carisolv, Conventional Diamond Burs
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Rehman Medical Institute - RMI
Dental Anxiety, Impacted Third Molar Tooth
Anxiety Control by Erythrina Mulungu
This study evaluated the effectiveness of the Erythrina mulungu in controlling anxiety in patients undergoing bilateral extraction of asymptomatic, impacted mandibular third molars.
- Trial name
- NCT01948622
- Testing
- Mulungu
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Liane Maciel de Almeida Souza
Tooth Impacted
Acute Inflammation After Wisdom Tooth Removal
Third molar (wisdom teeth) extraction is one of the most frequent intervention in dentistry. Nevertheless, little is known about the level of general body inflammation of subjects with impacted or semi-impacted third molars.
- Trial name
- OTTO-SYST (NCT03048175)
- Testing
- Wisdom tooth removal
- Volunteers
- 40 people
- Sponsor
- University of Pisa
Implant Site Reaction, Tooth Extraction Status Nos
Elamrousy Modified Approach for Socket Shield Technique
The current trial aim was to evaluate clinically and radiographically the changes around dental implants inserted immediately in maxillary anterior esthetic zone using a novel combination of autogenous demineralized dentin graft…
- Conditions
- Implant Site Reaction, Tooth Extraction Status Nos, Dental Implant Failed
- Trial name
- NCT06043037
- Testing
- Elamrousy Novel Approach for Immediate Implant Placement Using Socket Shield Technique, Immediate Implant Placement Using Socket Shield Technique alone
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Kafrelsheikh University
TEETH EXTRACTION, Esthetic Zone Implantology
Guided Root Slice Replantation vs. Socket Shielding for Immediate Implant Placement in Esthetic Zone
The goal of this clinical trial is to learn whether two different tooth-preservation techniques work equally well when placing a dental implant right after a tooth is removed in the front of the mouth (the "esthetic zone").
- Conditions
- TEETH EXTRACTION, Esthetic Zone Implantology, Socket Shield Technique Implant Placement, Root Slicing
- Trial name
- NCT07845019
- Testing
- Guided socket shield with immediate implant, Guided Autogenous Root Slicing Replantation with Immediate Implant, Conventional Bone Augmentation with Immediate Implant
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Minia University
Direct Oral Anticoagulants (DOACs)
LED Application Following Dental Extraction in Patients Taking Direct Oral Anticoagulants.
The DENT-DOAC trial is a single-blinded RCT investigating the effectiveness of LED application following dental extractions in patients taking direct oral anticoagulants (DOACs) .
- Trial name
- DENT-DOAC (NCT06971081)
- Testing
- LED light
- Where
- United Kingdom
- Volunteers
- 50 people
- Sponsor
- University College, London
Tooth Extraction, Molar, Third
Acupuncture on Anxiety and Inflammatory Events Following Surgery of Mandibular Third Molars
The aim of this study was to compare the effect of acupuncture and placebo acupuncture for the control of pain, edema, and trismus following the extraction of third molars and control of preoperative anxiety.
- Conditions
- Tooth Extraction, Molar, Third, Pain, Postoperative, Trismus
- Trial name
- NCT03545022
- Testing
- Acupuncture
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Dental Anxiety, Pain
SleeperOne vs. Conventional Infiltration: Pain Perception in Mandibular Primary Molar Extraction
This clinical trial is being conducted in the Department of Pediatric Dentistry, Faculty of Dentistry, Cairo University. The purpose of the study is to compare the pain perception and comfort of children during tooth extraction…
- Conditions
- Dental Anxiety, Pain, Pain Management, Extraction, Tooth
- Trial name
- SOTIMAN (NCT07156396)
- Testing
- SleeperOne®, dental Hitec, France, Conventional Infiltration
- Volunteers
- 28 people
- Sponsor
- Ameera Alaa Eldin Abdalazim Khalifa
Abrasion, Discoloration, Tooth
Enamel Abrasion and Stain Removal Efficacy
Enamel abrasion and stain removal efficacy of two whitening toothpastes
- Trial name
- NCT05619315
- Testing
- Charcoal -based whitening toothpaste, Calcium carbonate /perlite containing whitening toothpaste.
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Cairo University
Alveolar Bone Loss
A Clinical Investigation to Evaluate the Healing of Tooth Extraction Sites Filled With BioRestore™
The aim of this study was to evaluate by histology and MSCT scans during a 7-month period, the efficacy of a bioactive glass (Inion BioRestore™) placed in human extraction sockets in the maintenance of alveolar ridge.
- Trial name
- NCT01105026
- Testing
- Alveolar Bone Defect Regeneration Following Tooth Extraction
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Trieste