Clinical trials: Tooth Caries
Decay, Dental
Evaluating the Efficiency of Newly Designed Prefabricated PMMA Crowns for Restoring Primary Teeth in Comparison to Stainless Steel and Zirconia Crowns
Evaluation of PMMA pediatric crowns
- Trial name
- NCT04479046
- Testing
- PMMA crowns
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Pediatric Obesity, Pediatric Dentistry
Oral Health in Children and Adolescents With Obesity and Normal Weight
We aimed to compare the oral health status (dmft/DMFT index, IDCAS-II, BEWE, plaque index, gingival index, probing depth) between normal-weight (NW) and obese (OW) children/adolescents.
- Trial name
- NCT06283602
- Testing
- oral health status
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Dental Caries
The Use of Pit and Fissure Sealants in Children Requiring Caries Related Dental Extractions
The purpose of thus study is to assess the feasibility and inform the planning of a proposed definitive randomised controlled clinical trial to investigate the efficacy of sealing permanent molars in children requiring caries…
- Trial name
- NCT02443896
- Testing
- Pit and Fissure Sealant of permanent molars, No sealant of permanent molars
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- University of Birmingham
Dental Caries
Glass Ionomer Sealant and Fluoride Varnish Study to Prevent Early Childhood Caries
The goal of this project is to conduct a community-based randomized clinical trial to compare the caries prevention efficacy of fluoride varnish applied every six months vs.
- Trial name
- GIFVT (NCT01129440)
- Testing
- Fluoride Varnish, Glass Ionomer Sealant
- Where
- United States
- Volunteers
- 597 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Caries
The Preventive Effect of 2-years Use of Hydroxyapatite Containing Toothpastes in Children.
The aim of this RCT was to verify the caries preventive efficacy of toothpastes containing biomimetic hydroxyapatite (H.A.) complex in children compared to traditional fluoridated toothpastes.
- Trial name
- NCT04906291
- Testing
- Toothpaste use
- Where
- Italy
- Volunteers
- 610 people, healthy volunteers welcome
- Sponsor
- Università degli Studi di Sassari
Dental Caries
Evaluation in Vivo of Dentifrice With Nanoencapsulated Fluoride
The literature recognizes that fluoride is the most widely used and studied means for dental remineralization. The use of fluoride toothpaste in brushing is considered more rational method for the prevention of caries.
- Trial name
- NCT03008759
- Testing
- Dentifrice 100% Nano-F, Dentifrice 50% Nano-F, Dentifrice standard
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Fabio Correia Sampaio
Dental Caries
Evaluation of a Low Fluoride Dentifrice for Caries Control
The aim of this randomized clinical trial is to evaluate the effect of pH and fluoride concentration in liquid dentifrices in the control of dental caries in early childhood, in non-fluoridated area.
- Trial name
- NCT01623362
- Testing
- Low-fluoride acidic dentifrice, conventional dentifrice, neutral pH and low-fluoride dentifrice
- Where
- Brazil
- Volunteers
- 212 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Preterm Birth, Periodontal Disease
Saving Lives at Birth: Primary Prevention of Periodontal Disease in Relation to Preterm Birth in Malawi
The hypothesis of the investigators' project is that comprehensive primary preterm birth prevention, inclusive of maternal oral health with xylitol chewing gum (the intervention), will reduce the rate of periodontal disease and…
- Conditions
- Preterm Birth, Periodontal Disease, Caries, Dental
- Trial name
- PPaX (NCT02333227)
- Testing
- Xylitol gum
- Where
- United States
- Volunteers
- 10,069 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Caries Active, Tooth Decay
Effects of Platelet and Leukocyte-rich Fibrin on Alveolar Ridge Maintenance Through Three-dimensional Analysis
Understanding, through accurate and reliable volumetric analysis, how the biomaterial (LPRF) and the thickness of the vestibular bone plate influence changes in bone volume after extraction, is essential for making clinical…
- Conditions
- Caries Active, Tooth Decay, Tooth Loss / Rehabilitation
- Trial name
- NCT07278180
- Testing
- Alveolar socket preservation with graft and flap surgery
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Guarulhos
Dental Caries, Quality of Life
Impact of Two Recall Intervals on Dental Caries Incidence, Anxiety and Quality of Life of Preschool Children
Objectives: To assess the effectiveness of two recall intervals on dental caries incidence (primary outcome) in preschool children with low and moderate caries risk.
- Conditions
- Dental Caries, Quality of Life, Anxiety
- Trial name
- NCT02263768
- Testing
- Oral clinical conditions
- Where
- Brazil
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Caries, Dental
Anterior Zirconia vs. Resin Strip Crowns
This study is comparing the effectiveness of two different dental crown fillings (resin crowns and zirconia crowns) for primary front teeth (incisors).
- Trial name
- NCT03889535
- Testing
- Resin strip crowns, Zirconia crowns
- Where
- Canada
- Volunteers
- 59 people
- Sponsor
- The Hospital for Sick Children
Dental Caries
Er:YAG Laser for Dental Cavity Preparation
The goal of this clinical trial is to compare Er:YAG laser cavity preparation with conventional rotary instruments in adults who have permanent premolars planned for extraction as part of orthodontic treatment.
- Trial name
- NCT07831720
- Testing
- Er:YAG Laser, Conventional Rotary Cavity Preparation
- Where
- Vietnam
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ho Chi Minh City Odonto-Stomatology Hospital
Early Childhood Caries
Effectiveness of Dental Caries Arrest Treatment in Primary Teeth Using AgNO3 Followed by NaF Varnish
Aim: This randomised controlled trial will systematically compare the efficacy of a 25% AgNO3 solution followed by 5% NaF varnish with that of a 38% SDF solution in arresting caries teeth among preschool children when applied at…
- Trial name
- NCT02019160
- Testing
- 25% AgNO3 solution followed by 5% NaF varnish
- Where
- China
- Volunteers
- 1,070 people
- Sponsor
- The University of Hong Kong
Tooth Disease
Clinical Evaluation of a Restorative Glass Ionomer and a Composite Resin for the Restoration
The clinical performances of a restorative glass ionomer and a composite resin will be compared in the restoration of non-carious cervical lesions (NCCLs) at patients with systemic diseases.
- Trial name
- NCT04266210
- Testing
- Fuji Bulk, G-ænial Posterior
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Hacettepe University
Dental Caries Extending to Pulp, Dental Implant Failed
Effect of Local Application of Simvastatin Versus Bone Powder on Implant Bone Changes
This study is conducted A- To investigate that PRF loaded with osteopromotive pharmacological drug can be a great aid in implant rehabilitation, and whether it could be a replacement for the other high price bone graft materials…
- Trial name
- NCT06016218
- Testing
- Simvastatin
- Where
- Egypt
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Caries,Dental
Nano-hydroxyapatite and Ozone - Effect on Approximal Initial Caries
Objectives: to assess the efficiency of three methods of enamel remineralization on initial approximal caries: 1. a nano-hydroxyapatite gel, 2. gaseous ozone therapy 3. combination of a nano-hydroxyapatite gel and ozone.
- Trial name
- NCT04147091
- Testing
- ApaCare & Repair
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Pomeranian Medical University Szczecin
Dental Caries, Caries Arrested
CARIES ARREST USING SILVER DIAMINE FLUORIDE VERSUS FISSURE SEALANT IN OCCLUSAL DENTAL CARIOUS LESIONS
The goal of this randomized clinical trial is to evaluate if Silver Diamine Fluoride (SDF) is a more conservative and effective treatment in preventing the progression of mild occlusal caries compared to fissure sealant in…
- Conditions
- Dental Caries, Caries Arrested, Silver Diamine Fluoride, Fissure Sealant
- Trial name
- NCT06861725
- Testing
- Silver Diamine Fluoride (SDF), VOCO Fissurit
- Where
- Egypt
- Volunteers
- 76 people
- Sponsor
- Cairo University
Dental Caries, Secondary Dental Caries
Influence of the Number of Layers of a One Bottle Adhesive on the Longevity of Composite Restorations in Primary Molars
The aim of this study is to determinate the influence of an alternative adhesive application protocol (i.e. consecutive application of an extra adhesive layer)on restoration longevity in primary molars.
- Trial name
- NCT01680289
- Testing
- Three adhesive coats, Two adhesive coats
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Rio de Janeiro
Dental Caries, Pulpotomies Primary Teeth
Ferric Sulfate and Sodium Hypochlorite Pulpotomies in Vital Primary Teeth
This study aims to compare the clinical and radiographic success of two commonly used pulpotomy agents, ferric sulfate (FS) and sodium hypochlorite (NaOCl), in vital primary molars.
- Trial name
- NCT07548008
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Marmara University
Caries, Dental
Clinical Evaluation of ELS Versus ELS Extra Resin Composite
Adhesive restorative materials are routinely used in operative dentistry to improve tooth tissues with minimal preparation, achieve more esthetic and long term restorations.
- Trial name
- NCT03306576
- Testing
- ELS Extra composite, ELS composite
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Istanbul Medipol University Hospital