Clinical trials: Tooth Bleaching
Dentin Sensitivity
Effect of Laser and Potassium Nitrate Application on the Sensitivity Control in Bleached Teeth
To investigate the effects of desensitizing agents on the dental bleaching process, testing the hypothesis that they may control dental sensitivity.
- Trial name
- NCT03434782
- Testing
- In-office dental bleaching, Low Level Laser Therapy, 5% potassium nitrate / 2% sodium fluoride gel
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dentin Hypersensitivity
A Study to Investigate the Tooth Whitening and Dentin Hypersensitivity Effectiveness of Two Experimental Toothpastes
The aim of this exploratory clinical study is to investigate the tooth whitening potential, Dentin Hypersensitivity (DH) efficacy, and oral tolerability of two experimental toothpastes in a DH population with appropriate tooth…
- Trial name
- NCT07297732
- Testing
- Test Toothpaste 1, Test Toothpaste 2, Reference Toothpaste
- Where
- United States
- Volunteers
- 254 people, healthy volunteers welcome
- Sponsor
- HALEON
Dentin Sensitivity
The Strontium Chloride Associated With Photobiomodulation in the Control of Post-bleaching Sensitivity
This study investigated the effects of the association of strontium chloride with photobiomodulation on the dental bleaching process, testing the hypothesis that they may control dental sensitivity post-bleaching teeth.
- Trial name
- NCT04356911
- Testing
- FBM, ESTRÔNCIO, FBM+ESTRÔNCIO
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dentin Sensitivity
Evaluation of the Effect of Fluoride and Laser Application on the Prevention of Sensitivity in Bleached Teeth
To investigate the effects of desensitizing agents on the dental bleaching process, testing the hypothesis that they may prevent dental sensitivity.
- Trial name
- NCT03044171
- Testing
- Low Level Laser Therapy, 1.1% Sodium Fluoride, In-office dental bleaching
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Discoloured Teeth
High Light Intensity Bleaching Versus Descending Light Intensities Bleaching on Post Bleaching Teeth Sensitivity
Compare teeth sensitivity using bleaching protocol with different light intensities (Philips Zoom!™ White Speed whitening gel and lamp, Discus Dental, Inc., Culver City, CA, USA.) versus bleaching protocol with the same light…
- Trial name
- NCT02888847
- Testing
- Philips Zoom! White Speed whitening lamp, Philips Zoom! Advanced power whitening lamp
- Where
- Egypt
- Volunteers
- 24 people
- Sponsor
- Cairo University
Tooth Whitening
Investigation of the Instant Tooth Whitening Effect of a Silica Toothpaste Containing Blue Covarine
The study investigates the effect of toothbrushing with a toothpaste containing blue covarine compared to a control toothpaste without blue covarine on tooth color.
- Trial name
- NCT03760367
- Testing
- Blue covarine toothpaste, Control toothpaste
- Where
- Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Molar Incisor Hypomineralisation
Etch-bleach-seal Technique in Managing Opacities Related MIH Using Icon®
Objectives: to compare aesthetic effectiveness of resin infiltration with/without using sodium hypochlorite in managing opacities of MIH on incisors, and to compare parent's satisfaction with results of both application…
- Trial name
- NCT07162077
- Testing
- Sodium hypochlorite 5.25%, ICON resin infiltration Material group in vivo
- Where
- Syria
- Volunteers
- 15 people
- Sponsor
- Latakia University
Tooth Discoloration, Morphologic Change
Influence of Polishing After Bleaching on Color Change and Enamel Morphology
This trial evaluated the influence of polishing on enamel color change after in-office bleaching treatment. It also evaluated the influence of polishing on tooth morphology and sensitivity.
- Conditions
- Tooth Discoloration, Morphologic Change, Tooth Sensitivity
- Trial name
- NCT05635253
- Testing
- Hydrogen Peroxide 35%, Hydrogen Peroxide 35% + Polishing whitened teeth
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Pulp Inflammation
Analysis of the Influence of Desensitizing Treatments on the Pulp Inflammatory Response in Bleached Teeth
This randomized, controlled, blinded clinical trial evaluated the effectiveness of different desensitizing protocols in preventing pulp inflammation after bleaching treatment with 35% hydrogen peroxide (PH) (Whiteness PH 35%).
- Trial name
- NCT04548674
- Testing
- Whiteness HP 35%, Whiteness HP 35% + LASER, Whiteness HP 35% + CPP
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dentin Sensitivity
Effect of 1.5% Potassium Oxalate on the Control of Tooth Sensitivity and Color Change After Home Bleaching
This double-blind randomized clinical trial evaluated the effect of 1.5% potassium oxalate on pain sensitivity control and color change after home tooth whitening.
- Trial name
- NCT05028335
- Testing
- Carbamide Peroxide (PC) 22%) + Potassium Oxalate gel 1.5%
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Tooth Sensitivity, Tooth Bleaching
Photobiomodulation Before or After Tooth Whitening
The objective is to evaluate the effect of photobiomodulation (PBM) applied before or after in-office tooth whitening in reducing tooth sensitivity (TS) and color change.
- Conditions
- Tooth Sensitivity, Tooth Bleaching, Laser Therapy
- Trial name
- NCT06518629
- Testing
- Photobiomodulation with low power laser
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Tooth Discoloration
Tooth Bleaching for Young Patients Using a Hydrogen Peroxide-based Gel
The aim of the present study was to evaluate colorimetric changes and tooth sensitivity in young patients submitted to tooth bleaching with 20% and 35% hydrogen peroxide.
- Trial name
- NCT02414464
- Testing
- 35% hydrogen peroxide, 20% hydrogen peroxide
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Tooth Sensitivity
The Effect of Bleaching Application Mode on Bleaching-induced Tooth Sensitivity.
The aim of this study is to evaluate the effect of single versus multiple application protocols for in-office dental bleaching using two different bleaching gels (Pola Office Plus, SDI, 37.5% HP and Opalescence Boost, Ultradent…
- Trial name
- NCT07173296
- Testing
- Opalescence XTra Boost 40% HP, Pola Office Plus 37.5% HP
- Where
- Jordan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Tooth Hypersensitivity
Effect of Different Desensitizing Agents on Post-bleaching Hypersensitivity and Shade Stability
This study compared the effect of four different desensitizing agents on shade stability and dental hypersensitivity following dental bleaching procedure. The follow-up periods ranged from 24 hours to 1 year.
- Trial name
- NCT06358924
- Testing
- Potassium nitrate with fluoride, Casein phosphopeptide-amorphous calcium phosphate with fluoride, Hydroxyapatite with fluoride
- Where
- Egypt
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Tooth Bleaching, Pain
The Effect of an Experimental Gel Based on Acmella Oleracea Extract in Reducing Post-bleaching Tooth Sensitivity
This randomized, double-blind clinical trial aimed to evaluate the effect of an experimental gel containing 10% jambu extract (Acmella Oleracea) in reducing postoperative tooth sensitivity caused by bleaching with 35% hydrogen…
- Conditions
- Tooth Bleaching, Pain, Dentin Desensitizing Agents
- Trial name
- NCT05725850
- Testing
- EG (Experimental A. Oleracea extract gel)
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Hypersensitivity, Hypersensitivity, Immediate
Assessment of Er:YAG Laser for the Control of Hypersensitivity During Tooth Whitening With Hydrogen Peroxide
Introduction: Tooth whitening is an aesthetic procedure with rapid results that improves the self-esteem and self-image of patients. However, one of the side effects is dentinal hypersensitivity.
- Conditions
- Hypersensitivity, Hypersensitivity, Immediate, Hypersensitivity Response
- Trial name
- NCT06538129
- Testing
- Hypersensitivity prevention protocol with Er:YAG laser, Hypersensitivity prevention protocol with neutral sodium fluoride gel
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Tooth Sensitivity
Evaluation of In-office Bleaching-induced Sensitivity With 2 or 7 Days Interval Between Sessions
Clinical randomized single-blind trial, used to measure the level of tooth sensitivity (TS) after in-office dental bleaching sessions, on volunteers using a modified visual analog scale (VAS).
- Trial name
- NCT06394557
- Testing
- In-office Dental Bleaching Conventional, In-office Dental Bleaching Alternative
- Where
- Brazil
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Medicaments Substances in Therapeutic Use
Potassium Oxalate and Placebo and Post-bleaching Sensitivity
Purpose: This study will determine the effectiveness of the use of desensitivity gels prior in office bleaching on risk and intensity of tooth sensitivity caused by in-office bleaching using 35% hydrogen peroxide.
- Trial name
- NCT03065673
- Testing
- Potassium oxalate 5% gel
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Flavia Pardo Salata Nahsan
Dental Hypersensitivity, Teeth Whitening
Effectiveness of 16% Carbamide Peroxide in Reducing Hypersensitivity During Alternate-day Home Bleaching
The concentration of 16% carbamide peroxide is the highest concentration that European regulations allow for use in home whitening (Council directive 2011/84/EU).
- Trial name
- NCT06035588
- Testing
- Daily whitening, Alternate whitening
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Tooth Whitening, Sensitivity
Effects of Desensitizing Dentifrices on the Reduction of Pain Sensitivity Caused by In-office Dental Whitening
Introduction: The pain sensitivity associated with whitening is the main problem reported by patients during dental whitening, and the use of desensitizing dentifrices is an alternative for the treatment of sensitivity.
- Trial name
- NCT03019224
- Testing
- Selection and preparation of the volunteers, Evaluation of the tooth color, Relative isolation
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil