Clinical trials: Tooth Bleaching
Teeth Sensitivity, Tooth Discoloration
Efficacy of CPP-ACP on Bleaching Related Sensitivity
Objective: The purpose of this randomized controlled split-mouth clinical trial was to evaluate the effectiveness of MI paste in reducing sensitivity associated vital bleaching.
- Trial name
- NCT04112706
- Testing
- CPP-ACP
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of New England
Whitening
Clinical Study to Evaluate the Tooth Whitening Efficacy
Optic White 5%HP ActivShine TP vs Crest3D White TP (head-to-head whitening clinical) The objective of this study is to evaluate the tooth whitening efficacy of a Colgate toothpaste with 5% Hydrogen Peroxide and Fluoride compared…
- Trial name
- NCT06957249
- Testing
- Optic White 5%HP ActivShine Toothpaste, Crest3DWhite Advanced Radiant Mint Toothpaste
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Tooth Discoloration
Impact of Dietary Counseling on Efficacy of Tooth Bleaching
The aim of this study will be to evaluate if subjects submitted to a white diet counseling during home dental bleaching will present better results than subjects that maintained their usual diets.
- Trial name
- NCT03528356
- Testing
- Regular diet
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Federal University of Pelotas
Tooth Whitening, Sensitivity
Effects of Desensitizing Dentifrices on the Reduction of Pain Sensitivity Caused by In-office Dental Whitening
Introduction: The pain sensitivity associated with whitening is the main problem reported by patients during dental whitening, and the use of desensitizing dentifrices is an alternative for the treatment of sensitivity.
- Trial name
- NCT03019224
- Testing
- Selection and preparation of the volunteers, Evaluation of the tooth color, Relative isolation
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Discoloration, Tooth
Bleaching Effect of Solo and Combined Kiwi Extract and Ozone and Their Impact on Enamel
ozone therapy has been extensively used in dentistry to manage wounds healing, dental caries, oral lichen planus, gingivitis and periodontitis, halitosis, osteonecrosis of the jaw, post-surgical pain, plaque and biofilms, root…
- Trial name
- NCT06582069
- Testing
- Bleaching
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Tooth Sensitivity, Tooth Bleaching
Photobiomodulation Before or After Tooth Whitening
The objective is to evaluate the effect of photobiomodulation (PBM) applied before or after in-office tooth whitening in reducing tooth sensitivity (TS) and color change.
- Conditions
- Tooth Sensitivity, Tooth Bleaching, Laser Therapy
- Trial name
- NCT06518629
- Testing
- Photobiomodulation with low power laser
- Where
- Brazil
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Bleaching; Satisfactory
The Correlation and Relationship Between Chromaticity Parameters and Treatment Satisfaction Before and After Tooth Bleaching
Explore the correlation and specific relationship between chromaticity parameters and treatment satisfaction before and after tooth bleaching, compare the curative effect of different tooth bleaching programs.
- Trial name
- NCT03153605
- Testing
- Common toothpaste
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Fujian Medical University
Sensitivity, Tooth
The Association of CPP-ACPF Associated With LASER in the Treatment of Tooth Sensitivity After at Home Bleaching
Tooth whitening is a procedure that has been increasingly requested by patients around the world, whether at home or in office bleaching. Tooth sensitivity is the main side effect of bleaching.
- Trial name
- NCT05298059
- Testing
- Laser of low frequncy, CPP-ACPF
- Where
- 2 sites in Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Medicaments Substances in Therapeutic Use
Potassium Oxalate and Potassium Nitrate and Post-bleaching Sensitivity
Objectives: This study will determine the effectiveness of the use of desensitivity gels prior in office bleaching on risk and intensity of tooth sensitivity caused by in-office bleaching using 35% hydrogen peroxide.
- Trial name
- NCT02941653
- Testing
- Potassium nitrate 2% gel, Potassium oxalate 5% gel
- Where
- Brazil
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe
Dental Devices, Home Care
Two Week Cumulative Extrinsic Stain Removal of a Battery-powered Toothbrush and a Manual Toothbrush
To evaluate and compare the extrinsic stain removal efficacy of a battery-powered toothbrush and a manual toothbrush following two weeks of brushing.
- Trial name
- NCT06292611
- Testing
- Battery operated toothbrush, Manual toothbrush
- Where
- United States
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Church & Dwight Company, Inc.
Tooth Discoloration
Clinical Effectiveness of In-office Bleaching Activated With a LED/Laser Device
There is a controversy in the dentistry literature about how the use of associated light to activate 35% hydrogen peroxide gel during in-office tooth bleaching may increase the bleaching effectiveness.
- Trial name
- NCT01231243
- Testing
- in-office bleaching with/without light
- Where
- Brazil
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidade Estadual de Ponta Grossa
Tooth Discoloration
Efficacy of Teeth Whitening Product Offerings in Adults
This is a 30 day randomized, parallel comparative trial where participants with tooth shade of C2 or darker will be assigned to one of five groups.
- Trial name
- NCT04124068
- Testing
- Hydrogen peroxide teeth whitening gel, GLO Brilliant Teeth Whitening Device, GLO Lit Teeth Whitening Device
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Glo Science, Inc.
Tooth Bleaching, Pain
Effects of an Experimental Propolis Gel on Tooth Sensitivity Control and Post-bleaching Color Change: a Randomized Clinical Trial
This randomized, parallel, double-blind, placebo-controlled clinical study aims to investigate the effects of an experimental 0.5% propolis gel on controlling tooth sensitivity and discoloration after in-office dental bleaching.
- Conditions
- Tooth Bleaching, Pain, Dentin Desensitizing Agents
- Trial name
- NCT07569276
- Testing
- Propolis gel, KF2- Potassium nitrate
- Where
- Brazil
- Volunteers
- 66 people
- Sponsor
- Universidade Federal do Para
Color, Bleaching Sensitivity
Whitening Efficacy and Tooth Sensitivity of Different Concentrations of Hydrogen Peroxide Photoactivated With Violet or Blue LEDs
This is a randomized, controlled, double-blind and repeated-measures clinical trial evaluated the photoactivation of hydrogen peroxide gels in different concentrations with blue or violet LED in terms of whitening efficacy and…
- Trial name
- NCT06165458
- Testing
- 6% hydrogen peroxide gel + violet LED, 6% hydrogen peroxide gel + blue LED, 35% hydrogen peroxide gel + violet LED
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Pulp Inflammation
Analysis of the Influence of Desensitizing Treatments on the Pulp Inflammatory Response in Bleached Teeth
This randomized, controlled, blinded clinical trial evaluated the effectiveness of different desensitizing protocols in preventing pulp inflammation after bleaching treatment with 35% hydrogen peroxide (PH) (Whiteness PH 35%).
- Trial name
- NCT04548674
- Testing
- Whiteness HP 35%, Whiteness HP 35% + LASER, Whiteness HP 35% + CPP
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Dentin Hypersensitivity
The Effect of Desensitizing Agents in In-home or In-office Dental Bleaching
The aim of this project is to evaluate in vitro and in vivo the effect of dental bleaching agents, carbamide peroxide 16% (T1) and hydrogen peroxide 35% (T2) together with desensitizers/remineralizer agents, Sensodyne® dentifrice…
- Trial name
- NCT02316080
- Testing
- Dental bleaching, Desensitizing therapy
- Where
- Brazil
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Tooth Discoloration
Efficacy of a Whitening Dentifrice on Tooth Discoloration
The purpose of this study was to compare the whitening effect of a toothpaste containing blue pigment with a conventional toothpaste and with at-home tooth bleaching; evaluate the subject's perception about tooth color…
- Trial name
- NCT02741427
- Testing
- Conventional toothpaste, Whitening toothpaste, 10% carbamide peroxide
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Federal University of Paraíba
Dental Caries, Tooth Discoloration
Color Stability of Darkly Discolored Arrested Caries Lesions Following Bleaching Treatment
This observational study evaluated the color stability of darkly discolored arrested caries lesions (DDACL) on anterior teeth following in-office bleaching with 40% hydrogen peroxide, in comparison with healthy teeth.
- Trial name
- NCT07886255
- Where
- Turkey (Türkiye)
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Discolored Teeth
In-office and At-home Tooth Bleaching Using Low Concentration Peroxides.
To evaluate the efficacy, safety and impact on quality of life related to oral health of home and office tooth whitening techniques in young individuals.
- Trial name
- NCT02816593
- Testing
- hydrogen peroxide 6%, hydrogen peroxide 15%, Carbamide Peroxide 10%
- Where
- Brazil
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Federal University of Minas Gerais
Teeth Whitening
Tooth Whitening Evaluation With Cytotoxic and Genotoxic Effect of Commercial Whitening Toothpastes on Oral Mucosal Cells
Bleaching discolored vital teeth is one of the most popular aesthetic treatment in dentistry in the last decade. Teeth whitening can be performed by professionals/dentists in the dental office ("in-office") and by the patients…
- Trial name
- NCT04460755
- Testing
- Control group, Whitening toothpaste 1, Whitening toothpaste 2
- Where
- Croatia
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Zagreb