Clinical trials: Tooth Bleaching
Tooth Whitening, Tooth Discoloration
Clinical Research Study to Evaluate Stain Removal and Whitening Improvement
The objective of this clinical research study is to evaluate the stain removal and whitening improvement of a toothpaste containing Vitamin C and 1100 ppm F as sodium fluoride as compared to a matching placebo toothpaste…
- Trial name
- NCT07870018
- Testing
- Vitamin C toothpaste
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dentin Sensitivity
Longevity and Effectiveness of Bleaching in Healthy and Smokers Patients
The main objective of this study is to evaluate the effectiveness and longevity of color and Tooth sensitivity of patients undergoing home whitening peroxide 10% carbamide ( Whiteness Perfect , FGM , Joinville , Santa Catarina …
- Trial name
- BLESMOK (NCT02017873)
- Testing
- Peroxide Carbamide 10% - Dental bleaching treatment
- Where
- 2 sites in Brazil, Chile
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Chile
Tooth Sensitivity
Different Concentrations of Potassium Nitrate in In-office Tooth Bleaching Sensitivity
The aim of this randomized, double-blind controlled clinical study was to evaluate the absolute risk and intensity of sensitivity to dental bleaching in adults on the application of two different gels based on potassium nitrate…
- Trial name
- NCT03323372
- Testing
- 3% potassium nitrate and 0.25% sodium fluoride, 5% potassium nitrate and 2% sodium fluoride
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Amazonas
Tooth Bleaching Pain
The Effect of an Experimental Gel Based on Copaiba Oil Resin in Reducing Post-bleaching Tooth Sensitivity
This randomized, double-blind clinical trial aimed to evaluate the effect of an experimental gel containing copaiba oil resin in reducing postoperative tooth sensitivity caused by bleaching with 35% hydrogen peroxide.
- Trial name
- NCT06066671
- Testing
- GCO (Experimental copaiba oil resin gel)
- Where
- Brazil
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Hypersensitivity, Hypersensitivity, Immediate
Assessment of Er:YAG Laser for the Control of Hypersensitivity During Tooth Whitening With Hydrogen Peroxide
Introduction: Tooth whitening is an aesthetic procedure with rapid results that improves the self-esteem and self-image of patients. However, one of the side effects is dentinal hypersensitivity.
- Conditions
- Hypersensitivity, Hypersensitivity, Immediate, Hypersensitivity Response
- Trial name
- NCT06538129
- Testing
- Hypersensitivity prevention protocol with Er:YAG laser, Hypersensitivity prevention protocol with neutral sodium fluoride gel
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Tooth Sensitivity
Evaluation of In-office Bleaching-induced Sensitivity With 2 or 7 Days Interval Between Sessions
Clinical randomized single-blind trial, used to measure the level of tooth sensitivity (TS) after in-office dental bleaching sessions, on volunteers using a modified visual analog scale (VAS).
- Trial name
- NCT06394557
- Testing
- In-office Dental Bleaching Conventional, In-office Dental Bleaching Alternative
- Where
- Brazil
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Tooth Bleaching
Whitening Efficacy of Dentifrice Containing 10% High Cleaning Silica, 0.5% Sodium Phytate and 0.5% Sodium Pyrophosphate
The objective of the present study was to compare the effects of a commercially available dentifrice containing 10% high cleaning silica base, 0.5% sodium phytate and 0.5% sodium pyrophosphate versus a negative control dentifrice…
- Trial name
- NCT04238429
- Testing
- Toothpaste containing 10% high cleaning silica base, 0.5% sodium phytate and 0.5% sodium pyrophosphate, Control toothpaste
- Where
- China
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Tooth Bleaching
The Efficacy and Safety of Tooth Bleaching Procedure Using Y10 Whitening Toothpaste and RF Current
Study title: The Efficacy and Safety of tooth bleaching procedure using Y10 Whitening toothpaste and RF current The Device: The Brighttonix Y10 Tooth Whitening system is indicated for use in painless non-invasive tooth whitening…
- Trial name
- NCT02841514
- Testing
- The Y10 Tooth Whitening system including the Y10 toothpaste and the Y10 device, OTC toothpaste and an unoperated Y10 device
- Volunteers
- healthy volunteers welcome
- Sponsor
- Brighttonix Medical Ltd.
Dental Hypersensitivity, Teeth Whitening
Effectiveness of 16% Carbamide Peroxide in Reducing Hypersensitivity During Alternate-day Home Bleaching
The concentration of 16% carbamide peroxide is the highest concentration that European regulations allow for use in home whitening (Council directive 2011/84/EU).
- Trial name
- NCT06035588
- Testing
- Daily whitening, Alternate whitening
- Where
- Spain
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Inflammation
Anti-inflammatory Steroids in the Prevention of Tooth Sensitivity
Clinical randomized, triple-blind, used to measure the level of tooth sensitivity on volunteers using a modified virtual analog scale (VAS).
- Trial name
- NCT02956070
- Testing
- Dexamethasone acetate, Potassium Nitrate
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Tooth Discoloration
A Comparative Study Between the Efficacy of Diode Laser and Nano-chitosan Gel on Activation of Non-vital in- Office Bleaching Agent
The growing demand for white smile between patients has increased over recent years, the development of techniques and improvement of materials permits searching for beautiful natural smile.
- Trial name
- NCT06782087
- Testing
- nano chitosan
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Misr University for Science and Technology
Tooth Bleaching, Tooth Sensitivity
Prevention of Bleaching Induced Sensitivity
This study aims to evaluate the use of different desensitizing agents before in-office bleaching. A total of 64 volunteers were randomly divided into four groups.
- Trial name
- NCT04855279
- Testing
- neutral sodium fluoride, ACP-CCP gel, nano-hydroxyapatite solution
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Medipol University
Consumption, Toxicity
Assessment of Peroxide Level in Saliva During Teeth Bleaching With 9.5% Hydrogen Peroxide Gel
Assessment of peroxide level in saliva during teeth bleaching with 9.5% hydrogen peroxide gel using a tray with reservoir versus a tray without reservoir. A randomized clinical trial
- Trial name
- NCT05605834
- Testing
- 9.5% hydrogen peroxide bleaching (POLA DAY advanced tooth whitening system, SDI) using a tray with reservoir, 9.5% hydrogen peroxide bleaching (POLA DAY advanced tooth whitening system, SDI) using a tray without reservoir.
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pulp Inflammation
Analysis of the Influence of Desensitizing Treatments on the Pulp Inflammatory Response in Bleached Teeth
This randomized, controlled, blinded clinical trial evaluated the effectiveness of different desensitizing protocols in preventing pulp inflammation after bleaching treatment with 35% hydrogen peroxide (PH) (Whiteness PH 35%).
- Trial name
- NCT04548674
- Testing
- Whiteness HP 35%, Whiteness HP 35% + LASER, Whiteness HP 35% + CPP
- Where
- Brazil
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Universidade Federal do Para
Staining
Clinical Study to Assess the Efficacy of Professional Tooth Whitening Maintenance System
Clinical study to assess the efficacy of professional tooth whitening maintenance system of a Colgate toothpaste containing 5% Hydrogen Peroxide with a stain-fighter mouthwash as compared to only the stainfighter mouthwash and a…
- Trial name
- NCT06613347
- Testing
- whitening maintenance, whitening maintenance MW, negative control
- Where
- United States
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Colgate Palmolive
Dental Atraumatic Restorative Treatment
Clinical Evaluation of Enamel Microhardness Using Tooth Whitening Agents
The investigator will review the medical history taken by the participants' orthodontist that determined participants eligibility to participate in this study on the first appointment.
- Trial name
- NCT07165366
- Testing
- Carbamide Peroxide 10%, Hydrogen Peroxide
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ultradent Products, Inc.
Dentin Hypersensitivity, Tooth Discoloration
Management of Dentinal Hypersensitivity Using Two Dentifrice Technologies
This study evaluates the effectiveness of Scigates foam mouth sanitizer 2 in 1 toothpaste and mouthwash in reducing tooth sensitivity and improving tooth whitening compared to Lacalut® White \& Repair toothpaste.
- Trial name
- NCT07511530
- Testing
- Scigates Foam Mouth Sanitizer 2 in 1 Toothpaste and Mouthwash, Lacalut White and Repair Toothpaste
- Where
- Jordan
- Volunteers
- 57 people, healthy volunteers welcome
- Sponsor
- Prof. Mayyas Al-Remawi
Tooth Sensitivity, Toothache
Piroxicam-beta-Cyclodextrin on Tooth Sensitivity Caused by In-office Bleaching
Objectives: This study aims to evaluate the effectiveness of preemptive administration of non-steroidal anti-inflammatory Piroxicam-beta-Cyclodextrin on risk and level of tooth sensitivity caused by in-office bleaching procedures…
- Trial name
- NCT03153657
- Testing
- Piroxicam-Beta-Cyclodextrin
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sergipe